ВОзвращает список болезней. Можно фильтр/искать

search, age, gender, parent, symptoms, sort_name, sort_by, rand, branches
GET /disease/?format=api&ordering=-block_rubric&page=530
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

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            },
            "code": "C74",
            "name": "Рак надпочечника",
            "icd_name": "Рак надпочечника",
            "gender": 0,
            "age_min": 0,
            "age_max": 94,
            "cause": [
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            "periodicity": 1,
            "slug": "c74_rak_nadpochechnika",
            "lead": "Нарушение здоровья, относящееся к группе злокачественное новообразование щитовидной железыи других эндокринных желез",
            "description": "Рак надпочечников – это злокачественное поражение ткани железы, которая размещается на верхней почечной поверхности. Опухоль надпочечника считается достаточно редким заболеванием и встречается в 5% онкологических больных. Новообразование очень часто метастазирует в такие органы как печень и легкие.",
            "etiology": "<p>Причины рака надпочечников наверняка не известны. Считается, что спровоцировать онкопроцесс могут факторы вроде:</p>\r\n<ul>\r\n<li>Употребления канцерогенных веществ, которые в больших количествах встречаются в некоторых напитках и пищевых продуктах;</li>\r\n<li>Нездоровых привычек типа употребления табакаили спиртного;</li>\r\n<li>Возрастных особенностей. Рак подобного характера поражает преимущественно маленьких детей и пациентов старшего возраста;</li>\r\n<li>Предрасположенности семейного характера, наличия генетической склонности к раковым надпочечниковым процессам;</li>\r\n<li>Множественных эндокринных опухолей;</li>\r\n<li>Наличие наследственных патологий вроде синдрома Ли-Фраумени, гиперпластического полипоза, Беквит-Видемана и пр.</li>\r\n</ul>",
            "pathogenesis": "<p>Основные теории, объясняющие патогенез опухолей:</p>\r\n<p>Мутационная теория канцерогенеза. Развитие опухолевого роста – следствие мутации. Химические канцерогенные вещества, излучения вызывают мутационный процесс – изменяется геном, изменяется структура клеток, идет малигнизация (озлокачествление).</p>\r\n<p>Эпигеномная теория канцерогенеза. Основой опухолевого процесса при этой теории является деперссия древних генов.</p>\r\n<p>Вирусная теория канцерогенеза. Вирусы длительно могут персистировать в клетках, находясь в латентном состоянии, под действием канцерогенов, физических факторов происходит их активация. Вирус встраивается в клеточный геном, внося дополнительную информацию в клетку, вызывая нарушение генома и нарушение жизнедеятельности клетки.</p>\r\n<p>Трансформированные клетки характеризуются:</p>\r\n<ul>\r\n<li>Нарушением дифференцировки;</li>\r\n<li>Неопределенно долгим делением без признаков старения;</li>\r\n<li>Дефектами апоптоза (генетически запрограммированного разрушения клетки).</li>\r\n</ul>",
            "diagnostics": "<p>Для диагностики гормонпродуцирующих опухолей надпочечников значение имеет определение содержания тех или иных гормонов в крови и в моче, а также определение содержания АКТГ (адренкортикотропного гормона) в крови - гормона гипофиза (железы, расположенной в головном мозге, регулирующей работу надпочечников).</p>\r\n<p>Используют визуализирующие методы, которые помогут выявить опухоль:</p>\r\n<p>компьютерную томографию (КТ) органов брюшной полости, надпочечников. Метод позволяет выявить образования размером более 5 мм. сцинтиграфию, которую используют, если есть подозрение на опухоль вне надпочечников. При проведении исследования нужно учитывать возможность ассиметричного накопления изотопа в нормальных надпочечниках. позитронно-эмиссионную томографию (ПЭТ). Этот метод более чувствителен, чем сцинтиграфия, в плане выявления метастатических поражений.</p>",
            "treatment": "<p>Основной метод терапии – хирургический. Проводится удаление надпочечника (адреналэктомия) вместе с близрасположенными лимфатическими узлами. При большой раковой опухоли, прорастающей в почку, может встать вопрос об удалении почки.</p>\r\n<p>Для лечения феохромоцитомы также применяется лечение радиоактивным изотопом. При инъекции в вену изотоп проникает в опухоль и вызывает гибель достаточного количества клеток для уменьшения размеров опухоли и даже для уменьшения размера метастазов. При некоторых опухолях хорошие результаты дает химиотерапия.</p>",
            "prevention": "<p>Поскольку причины развития опухолей надпочечников до конца не установлены, профилактика сводится к предупреждению рецидивов удаленных опухолей и возможных осложнений. После адреналэктомии необходимы контрольные обследования пациентов эндокринологом 1 раз в 6 мес. с последующей коррекцией терапии в зависимости от самочувствия и результатов исследований.</p>\r\n<p>Пациентам после адреналэктомии по поводу опухолей надпочечников противопоказаны физические и психические нагрузки, употребление снотворных средств и алкоголя.</p>\r\n<p> </p>",
            "clinical_picture": "<p>Альдостеромы проявляются тремя группами симптомов: сердечно-сосудистыми, почечными и нервно-мышечными. Отмечаются стойкое повышение артериального давления, не поддающееся гипотензивной терапии, головные боли, одышка, перебои в сердце, гипертрофия, а затем дистрофия миокарда. Стойкая гипертензия приводит к изменениям глазного дна.</p>\r\n<p>При резком выбросе альдостерона может развиваться криз, проявляющийся рвотой, сильнейшей головной болью, резкой миопатией, поверхностными дыхательными движениями, нарушением зрения, возможно - развитием вялого паралича или приступа тетании.</p>\r\n<p>Почечные симптомы альдостеромы развиваются при резко выраженном снижении уровня калия в крови: появляются жажда, повышенное образование мочи, преобладание ночного диуреза, щелочная реакция мочи.</p>\r\n<p>Нервно-мышечные проявления альдостеромы: мышечная слабость различной степени выраженности, парестезии (онемение) и судороги - обусловлены сниженным уровнем калия в крови, развитием внутриклеточного ацидоза и дистрофией мышечной и нервной ткани.</p>\r\n<p>У 6-10 % пациентов с данным видом опухолей надпочечников встречается бессимптомное течение альдостеромы.</p>\r\n<p>Клиника кортикостеромы соответствует проявлениям гиперкортицизма (синдрома Иценко-Кушинга). Развивается ожирение по кушингоидному типу, гипертензия, головная боль, повышенная мышечная слабость и утомляемость, стероидный диабет, половая дисфункция. На животе, молочных железах, внутренних поверхностях бедер отмечается появление стрий (растяжек) и петехиальных кровоизлияний. У мужчин развиваются признаки феминизации – увеличение грудных желез (гинекомастия), гипоплазия (уменьшение) яичек, снижение потенции; у женщин, напротив, признаки вирилизации – мужской тип оволосения, понижение тембра голоса, гипертрофия клитора.</p>\r\n<p>Развивающийся остеопороз может стать причиной компрессионного перелома тел позвонков. У четверти пациентов с данной опухолью надпочечников выявляется пиелонефрит и мочекаменная болезнь. Нередко отмечается нарушение психических функций: депрессия или возбуждение.</p>\r\n<p>Проявления кортикоэстеромы у девочек связаны с ускорением физического и полового развития (увеличением наружных половых органов и молочных желез, оволосением лобка, ускорением роста и преждевременным созреванием скелета, влагалищными кровотечениями), у мальчиков – с задержкой полового развития. У взрослых мужчин развиваются признаки феминизации – двустороннее увеличение грудных желез, атрофия полового члена и яичек, отсутствие роста волос на лице, высокий тембр голоса, распределение жировых отложений на теле по женскому типу, снижение уровня активных спермотозоидов, снижение или утрата потенции.</p>\r\n<p>У женщин эта опухоль надпочечников симптоматически никак себя не проявляет и сопровождается только увеличением концентрации в крови эстрогенов.</p>\r\n<p>Андростеромы, характеризующиеся избыточной продукцией андрогенов опухолевыми клетками (тестостерона, андростендиона, дегидроэпиандростерона и др.), вызывают развитие анаболического и вирильного синдромов. При андростероме у детей отмечается ускоренное физическое и половое развитие – быстрый рост и мышечное развитие, огрубение тембра голоса, появление угревой сыпи на туловище и лице. При развитии андростеромы у женщин появляются признаки вирилизации – прекращение менструаций, гирсутизм (повышенное оволосенение), снижение тембра голоса, гипотрофия матки и молочных желез, гипертрофия клитора, уменьшение подкожно-жирового слоя, повышение либидо. У мужчин проявления вирилизма выражены меньше, поэтому эти опухоли надпочечников часто являются случайными находками.</p>\r\n<p>Развитие феохромоцитомы сопровождается опасными гемодинамическими нарушениями и может протекать в трех формах: пароксизмальной, постоянной и смешанной. Течение наиболее частой пароксизмальной формы (от 35 до 85%) проявляется внезапной, чрезмерно высокой артериальной гипертензией (до 300 и выше мм рт. ст.) с головокружением, головной болью, мраморностью или бледностью кожных покровов, сердцебиением, потливостью, загрудинными болями, рвотой, дрожью, чувством паники, полиурией, подъемом температуры тела. Приступ пароксизма провоцируется физическим напряжением, пальпацией опухоли, обильной едой, алкоголем, мочеиспусканием, стрессовыми ситуациями (травмами, операцией, родами и др.).</p>\r\n<p>Пароксизмальный криз может длиться до нескольких часов, повторяемость кризов – от 1 в течение нескольких месяцев до нескольких в день. Криз прекращается быстро и внезапно, артериальное давление приходит к исходной величине, бледность сменяется покраснением кожных покровов, наблюдаются обильное потоотделение и секреция слюны. При постоянной форме феохромоцитомы отмечается стойко повышенное артериальное давление. При смешанной форме данной опухоли надпочечников феохромоцитомные кризы развиваются на фоне постоянной артериальной гипертензии.</p>\r\n<p> </p>\r\n<p> </p>",
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            "code": "C73",
            "name": "Рак щитовидной железы",
            "icd_name": "Рак щитовидной железы",
            "gender": 0,
            "age_min": 40,
            "age_max": 55,
            "cause": [
                "0",
                "3"
            ],
            "periodicity": 0,
            "slug": "c73_rak_schitovidnoy_zhelezy",
            "lead": "злокачественная опухоль щитовидной железы, развивающаяся из фолликулярных или из С-клеток.",
            "description": "<p>Самый распространенный тип онкологических заболеваний &ndash; это папиллярный рак щитовидной железы, встречающийся более чем в 75% случаях. Как правило, такая опухоль возникает из здоровой ткани щитовидной железы и показывает себя, как новообразование в виде кисты или неравномерной, солидной опухоли. Папиллярный рак можно считать одним из самых поддающихся лечению видов злокачественных опухолей. В 85% случаях онкобольные излечиваются полностью от данного вида рака.</p>",
            "etiology": "<p>Современная медицина не имеет точных и доказанных причин возникновения опухолей на щитовидной железе, в частности папиллярного рака. Наиболее вероятной причиной считается мутация клеток на уровне ДНК. Причины возникновения мутаций также не известны. Клеточная структура щитовидной железы образует опухоли после мутаций клеток, которые начинают активно расти. Рост злокачественных клеток происходит постепенно, поражая здоровые ткани органа. По мнению медиков, папиллярный рак щитовидной железы может возникать по следующим причинам:</p>\r\n<ul>\r\n<li>Дефицит йода в организме человека;</li>\r\n<li>Врожденный фактор;</li>\r\n<li>Влияние окружающей среды, плохой экологии;</li>\r\n</ul>",
            "pathogenesis": "",
            "diagnostics": "<p>Первичное диагностирование злокачественной опухоли в щитовидной железе может проводиться врачом путем пальпирования шейной области. При наличии уплотнений и узлов пациента направляют на ультразвуковое исследование. Однако окончательный и точный диагноз может быть поставлен только после проведения гистологического анализа узла, отсеченного из железы или удаленного лимфаузла. Выявление метастазов в костной ткани и легких осуществляется при помощи рентген-исследования.</p>\r\n<p>При возникновении небольших опухолей, которые не прощупываются, могут возникнуть затруднения в диагностировании заболевания, так как увеличение лимфатических узлов в шейном отделе указывает еще на ряд других заболеваний. Чтобы подтвердить или опровергнуть папиллярный рак щитовидной железы проводится гистологический анализ отсеченного лимфатического узла.</p>",
            "treatment": "<p>Современная медицина имеет в своем арсенале эффективный метод лечения рака щитовидной железы, который состоит из двух этапов:</p>\r\n<ol type=\"1\" start=\"1\">\r\n<li>Оперативное вмешательство хирургов;</li>\r\n<li>Проведение процедур с радиоактивным йодом.</li>\r\n</ol>\r\n<p>На первом этапе лечения проводится хирургическая операция по отсечению больных клеток органы или полное отсечение щитовидной железы. При поражении рядом находящихся лимфатических узлов выполняется полное или частичное удаление лимфаузлов в шейном отделе. Статистика указывает, что папиллярный рак чаще всего поражает лимфатические узлы, расположенные рядом с гортанью и трахеей.</p>\r\n<p>На втором этапе лечения проводятся процедуры с радиоактивным йодом. Такое лечение показано больным со злокачественной опухолью и наличием метастазов в лимфатических узлах, а так же при прорастании злокачественных образований через оболочку органа. Клетки, вырвавшиеся из железы, являются очень опасными. Терапия с радиоактивным йодом убивает оставшиеся после оперативного вмешательства раковые клетки. Обычно опухолевые клетки могут оставаться в самой щитовидной железе. Кроме этого, радиоактивный йод эффективно борется с метастазами, расположенными в легких, лимфатический системе.</p>",
            "prevention": "",
            "clinical_picture": "<p>Первый признак &ndash; появление на щитовидной железе небольшого узелка. Он заметен под кожей и имеет вид небольшого возвышения с одной стороны. На начальных этапах узелок может быть эластичный и безболезненный, его подвижность ограничена. Он не врос в кожу, а перекатывается под ней. Со временем узел становится более плотным и увеличивается в размерах.</p>\r\n<p>Еще один ранний симптом рака щитовидной железы &ndash; увеличение лимфатического узла на шее. Иногда это единственный признак болезни.<br /><br />На поздних этапах, когда опухоль становится более крупная, появляются и другие симптомы:<br /><br /></p>\r\n<ul>\r\n<li>боль в области шеи, которая может отдавать в ухо;</li>\r\n<li>затруднение глотания;</li>\r\n<li>ощущение комка в горле;</li>\r\n<li>осиплость голоса;</li>\r\n<li>кашель, который не связан с простудой или аллергией;</li>\r\n<li>одышка и затрудненное дыхание;</li>\r\n<li>набухание шейных вен.</li>\r\n</ul>\r\n<p><br />Эти симптомы вызваны тем, что опухоль достигла крупных размеров и начала сдавливать окружающие органы: пищевод, трахею. Метастазы в голосовых связках и возвратном гортанном нерве, который проходит рядом с железой &ndash; причина изменения <a title=\"Перейти на страницу симптома Слуховые галлюцинации\" href=\"/symptom/sluhovye_gallyucinacii/\">голоса</a>.</p>",
            "image": "http://api.symptomd.ru/storage/276b38be71ce24923c55309e1e056df6_fRNFVoQ.png",
            "image_alt": "Рак щитовидной железы",
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            "lead": "аномальные образования, которые развиваются в питуитарной железе",
            "description": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Опухоли гипофиза &ndash; это новообразования, возникающие вследствие аномального размножения клеток данной железы, приводящие к изменению уровня выработки гормонов, регулирующих важнейшие функции организма, а также появлению различных неврологических расстройств.</span></p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В большинстве своем опухоли гипофиза являются доброкачественными новообразованиями (так называемая аденома гипофиза). Такие опухоли локализуются исключительно в гипофизе и не распространяются на прилегающие ткани.</span></p>",
            "etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Аденома гипофиза может возникнуть, когда отдельные железистые клетки гипофиза вырождаются и начинают расти неконтролируемо. Почему это происходит, до сих пор не выяснено.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">У некоторых пациентов аденома гипофиза развивается в рамках множественного эндокринного новообразования. Это наследуемая картина болезни, при которой из-за дефекта гена несколько гормональных желез имеют патологические изменения.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ряд факторов, стимулирующих образование аденомы гипофиза:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">черепно-мозговая травма;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">туберкулез, бруцеллез;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нейросифилис;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">полиомиелит, энцефалит, менингит;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">абсцесс мозга;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">церебральная малярия;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">длительное применение оральных контрацептивов.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>",
            "pathogenesis": "",
            "diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Необходимыми исследованиями при подозрении на опухоль гипофиза являются тщательное офтальмологическое и гормональное обследования, нейровизуализация аденомы. Исследование мочи и крови на содержание гормонов позволяет установить вид опухоли гипофиза и степень ее активности. Офтальмологическое обследование включает оценку остроты и полей зрения, позволяющих судить о вовлеченности в процесс зрительных нервов.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нейровизуализацию опухоли гипофиза позволяет осуществить рентгенография черепа и зоны турецкого седла, МРТ и КТ головного мозга. Рентгенологически могут определяться увеличение размеров турецкого седла и эрозия его дна, а также увеличение нижней челюсти и пазух носа, утолщение костей черепа, и расширение межзубных промежутков. С помощью МРТ головного мозга возможно увидеть опухоли гипофиза диаметром менее 5 мм. Компьютерная томография подтверждает наличие аденомы и ее точные размеры.</span></p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При макроаденомах ангиография сосудов головного мозга указывает на смещение сонной артерии и позволяет дифференцировать опухоль гипофиза с внутричерепной аневризмой. В анализе спинномозговой жидкости может определяться повышенный уровень протеинов.</span></p>",
            "treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Не во всех случаях пациенты с аденомой гипофиза нуждаются в операции. Гормональные опухоли, такие как пролактинома, поддаются медикаментозному лечению. Терапия зависит от уровня дискомфорта, влияния на гормональный обмен организма и от и гормональной активности опухоли.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если аденома гипофиза не вызывает симптомов, ее не обязательно лечить. Но необходимо держать опухоль под постоянным контролем.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основные направления лечения опухоли гипофиза:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">заместительная гормонотерапия;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">оперативное вмешательство;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">лучевая терапия.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Некоторые типы аденом гипофиза не требуют оперативного вмешательства. Однако, если медикаментозная терапия не работает или у пациента замечена индивидуальная непереносимость лекарств, врачи рассматривают оперативное вмешательство.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Существует несколько способов хирургического лечения аденомы гипофиза:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">трансназальный (через нос);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">путем трепанации черепа;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">стереотаксический (радиохирургия).</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лучевая терапия используется для уменьшения опухоли в предоперационный период. При слишком сильных гормональных нарушениях больному назначается медикаментозное лечение перед хирургическим вмешательством. Радиохирургия дает возможность с максимальной точностью воздействовать на патологический очаг, не затрагивая при этом окружающие ткани.</span></p>",
            "prevention": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Первичной профилактики опухоли гипофиза не существует. Врачам до сих пор не удалось определить точного механизма развития патологии. Вторичная профилактика заключается в ранней диагностике болезни, регулярной сдаче крови на гормональное обследование, ведении здорового образа жизни.</span></p>",
            "clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Клиническое проявление аденомы связано с давлением опухолевого образования на определенные области мозга.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основные симптомы аденомы гипофиза:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">головная боль;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">ограничение поля зрения;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">вторичная аменорея;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">галакторея;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">импотенция/пониженное либидо;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">признаки болезни Кушинга;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">акромегалия.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В зависимости от того, какие гормоны вырабатывает опухоль, могут возникать и другие симптомы, т. к. происходит гормональный дисбаланс и возникает недостаточная или гиперфункция эндокринных органов. Но опухоль может протекать без симптомов. Многие из образований остаются незамеченными на протяжении всей жизни или обнаруживаются случайно.</span></p>",
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