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"code": "N19",
"name": "Почечная недостаточность неуточненная",
"icd_name": "Почечная недостаточность неуточненная",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
3
],
"periodicity": 1,
"slug": "n19_pochechnaya_nedostatochnost_neutochnennaya",
"lead": "Нарушение здоровья, относящееся к группе почечная недостаточность",
"description": "\r\nПочечная недостаточность – это патологическое состояние, при котором частично или полностью утрачивается способность почек образовывать и (или) выделять мочу, и, как следствие, развиваются серьезные нарушения водно-солевого, кислотно-щелочного и осмотического гомеостаза организма, которые приводят к вторичному повреждению всех систем организма.\r\n",
"etiology": "<p>Причины острой почечной недостаточности</p>\r\n<ul>\r\n<li>Нарушение почечной гемодинамики (шок, коллапс и др.);</li>\r\n<li>Экзогенные интоксикации (яды, применяемые в народном хозяйстве и быту, укусы ядовитых змей и насекомых, лекарственные препараты);</li>\r\n<li>Инфекционные болезни (геморрагическая лихорадкас почечным синдромом и лептоспироз);</li>\r\n<li>Острые заболевания почек (острый гломерулонефрит и острый пиелонефрит);</li>\r\n<li>Обструкция мочевых путей (острое нарушение оттока мочи);</li>\r\n<li>Аренальное состояние (травма или удаление единственной почки).</li>\r\n</ul>\r\n<p>Хроническая почечная недостаточность (ХПН) может быть следствием:</p>\r\n<ul>\r\n<li>Заболеваний почек (хронический диффузный гломерулонефрит, хронический пиелонефрит, амилоидозпочек и др.);</li>\r\n<li>Динамических или механических нарушений проходимости мочевых путей (почечнокаменная болезнь, сужение уретрыи т. д.);</li>\r\n<li>Сердечно-сосудистых и коллагеновых болезней;</li>\r\n<li>Эндокринных нарушений (например, сахарный диабет) и др.</li>\r\n</ul>",
"pathogenesis": "<p>При острой почечной недостаточности, обусловленной преренальными факторами, причиной, запускающей патологический механизм, является недостаточность кровоснабжения (ишемия) почечной ткани. Даже кратковременное снижение артериального давления ниже 80 мм рт. ст. приводит к резкому снижению кровотока в паренхиме. Подобное состояние может возникнуть при шоке любой этиологии, а также в результате кровотечения, в том числе при хирургическом вмешательстве. В ответ на ишемию начинается гибель и отторжение эпителия проксимальных канальцев почки. Резко нарушается обратное всасывание натрия, что стимулирует выработку ренина, который поддерживает спазм приносящих кровь сосудов и недостаточность кровоснобжения почечной паренхимы.</p>\r\n<p>При токсическом поражении также чаще всего страдает эпителий проксимальных канальцев, при этом в случае токсического воздействия пигментов миоглобина и гемоглобина ситуация усугубляется обтурацией канальцев этими белками.</p>\r\n<p>При остром гломерулонефрите острая почечная недостаточность может быть обусловлена как отеком интерстициальной ткани, повышением давления в проксимальных канальцах, что приводит к резкому снижению клубочковой фильтрации, так и быстро развивающимися процессами разрастания соединительной ткани в клубочках со сдавлением канальцевых петель и высвобождением биологически активных веществ, вызывающих спазм сосудов и ишемию.</p>\r\n<p>При постренальной острой почечной недостаточности нарушение оттока мочи из почек вызывает перерастяжение мочеточников, лоханок, собирательных канальцев и дистального и проксимального отделов нефрона. Следствием этого является массивный интерстициальный отек. Если отток мочи восстанавливается достаточно быстро, изменения почек обратимы, однако при длительно существующей обструкции возникают тяжелые нарушения кровообращения почек, которые могут закончиться тубулярным некрозом.</p>\r\n<p>В результате хронического патологического процесса в почечной паренхиме происходят необратимые изменения, связанные с уменьшением количества функционирующих нефронов и замещением пораженных клеток соединительной тканью. На первых порах здоровые нефроны берут на себя функцию пораженных, однако со временем компенсаторные возможности почек истощаются, продукты обмена не выводятся с мочой, а накапливаются в организме, повреждая другие ткани и органы</p>",
"diagnostics": "<p>При ОПН наблюдается непрерывное повышение уровня азотистых метаболитов и калия в крови наряду с уменьшением количества выделяемой мочи.</p>\r\n<p>Выполняется УЗИ почек, которое позволяет определить или исключить факт двусторонней обструкции верхних мочевых путей по наличию или отсутствию дилатации чашечно-лоханочной системы.</p>\r\n<p>При необходимости может быть выполнена двусторонняя катетеризация почечных лоханок. При свободном проведении мочеточниковых катетеров до лоханок и при отсутствии выделения по ним мочи можно исключить обструкцию (закупорку) мочевых путей.</p>\r\n<p>Лабораторная диагностика включает измерение объема мочи, уровня креатинина, мочевины и электролитов сыворотки крови.</p>\r\n<p>Для характеристики почечного кровотока может применяться почечная ангиография.</p>\r\n<p>Биопсия почки выполняется по строгим показаниям: при подозрении на острый гломерулонефрит, канальцевый некроз или системное заболевание.</p>\r\n<p>При подозрении на развитие хронической почечной недостаточности пациенту необходимо проведение лабораторных исследований: биохимический анализ крови и мочи, проба Реберга. Основанием для постановки диагноза становится снижение уровня клубочковой фильтрации, возрастание уровня креатинина и мочевины.</p>\r\n<p>При проведении пробы Зимницкого выявляется снижение плотности мочи. УЗИ почек свидетельствует о снижении толщины паренхимы и уменьшении размера почек. Снижение внутриорганного и магистрального почечного кровотока выявляется на ультразвуковом исследовании сосудов почек.</p>\r\n<p>Рентгенконтрастную урографию следует применять с осторожностью из-за нефротоксичности многих контрастных препаратов.</p>\r\n<p> </p>\r\n<p> </p>",
"treatment": "<p>Ограничивается прием жидкости, при повышенном содержании воды в организме жидкость исключают почти полностью. Ограничивается прием калия, натрия, белка.</p>\r\n<p>Для стимуляции диуреза больному назначают фуросемид и осмотические диуретики. Для уменьшения спазма почечных сосудов вводят допамин.</p>\r\n<p>Консервативное лечение почечной недостаточности начинают уже на ранних стадиях её развития и определяют выраженностью основного заболевания и ХПН, наличием осложнений со стороны других органов и систем.</p>\r\n<p>Для небольшого уменьшения содержания азотистых шлаков в сыворотке крови можно использовать энтеросорбенты, связывающие креатинин, мочевину и другие токсичные продукты, секретируемые в желудочно-кишечном тракте.</p>\r\n<p>Лечение должно включать назначение препаратов кальция в сочитании с витамином Д для профилактики остеодистрофий.</p>\r\n<p>Применение ингибиторов АПФ способствует профилактике прогрессирования склеротических изменений в почках в следствие уменьшения кровоснабжения почки с снижения артериального давления.</p>\r\n<p>Ранняя корекция анемии включает назначение эритропоэтина бета.</p>\r\n<p>В лечении применяется гемодиализ (аппарат «искусственная почка») – метод внепочечного очищения крови. Во время гемодиализа происходит удаление из организма токсических продуктов обмена веществ, нормализация нарушений водного и электролитного балансов.</p>\r\n<p>Перитонеальный диализ. Брюшную полость человека выстилает брюшина, которая выполняет роль мембраны, через которую поступают вода и растворенные в ней вещества. В брюшную полость хирургическим путем устанавливают специальный катетер, через который поступает диализирующий раствор в брюшную полость. Происходит обмен между раствором и кровью пациента, в результате чего удаляются вредные вещества и избыток воды. Раствор находится там несколько часов, а затем сливается.</p>\r\n<p>Хирургическое лечение – трансплантация почки – оптимальный метод коррекции конечной стадии ХПН.</p>",
"prevention": "<p>Профилактикой развития данной патологии является воздержание от применения нефротоксичных препаратов, рентгенконтрастных веществ при наличии почечной патологии, применение мочегонных средств, своевременная диагностика и лечение заболеваний, которые могут приводить к развитию почечной недостаточности.</p>",
"clinical_picture": "<p>Острая почечная недостаточность</p>\r\n<p>В начальную стадию, когда изменения функций почек носят минимальный характер, о угрозе развития почечной недостаточности говорит только незначительное снижение количества диуреза (соотношение потребленной жидкости к выделенной). Этот факт необходимо учитывать, особенно, если он появляется на фоне какого-либо заболевания.</p>\r\n<p>На стадии олигоанурии нарушения функций почек становятся более заметными. Общий диурез снижен не менее чем на 75%. Повышение токсичных веществ в крови вызывает увеличение частоты дыхательных движений (тахипноэ) и сердечных сокращений (тахикардия). Снижение количества мочи, а значит и увеличение жидкости в организме, приводит к появлению отеков и повышению артериального давления.</p>\r\n<p>Больной в этот период отмечает анорексию, тошноту и рвоту, сопровождающуюся поносом, который через некоторое время сменяется запором. Пациенты сонливы, заторможены, нередко впадают в кому. Может развиться отек легкого, который проявляется одышкой, влажными хрипами, нередко возникает патологическое дыхание Куссмауля.</p>\r\n<p>Гиперкалиемия обусловливает выраженные нарушения сердечного ритма. Нередко на фоне уремии возникает перикардит. Другим проявлением повышения содержания мочевины сыворотки крови является уремический гастроэнтероколит, следствием которого являются желудочно-кишечные кровотечения, возникающие у 10% больных с острой почечной недостаточности.</p>\r\n<p>В этот период отмечается выраженное угнетение фагоцитарной активности, в результате чего больные становятся подверженными инфекции. Возникают пневмонии, паротиты, стоматиты, панкреатиты, инфицируются мочевые пути и послеоперационные раны. Возможно развитие сепсиса.</p>\r\n<p>В стадию полиурии массовая гибель нефронов, в том числе канальцев, плазма крови начинает переходить в мочевые протоки (так как канальце ее не всасывают), что приводит к резкому повышению диуреза значительно выше нормы. Это называется полиурией, что и послужило поводом для наименования данной стадии. Кроме полиурии, отмечается тахикардия более 120-150 ударов в минуту, тахипноэ 30 и более, дыхательных движений, сухость кожи и ее повышенное шелушение, угнетение сознания, вплоть до развития комы.</p>\r\n<p>В фазу полного выздоровления происходит дальнейшее восстановление функции почек. Продолжительность этого периода достигает 6-12 мес, по прошествии которых функция почек восстанавливается полностью.</p>\r\n<full></full>\r\n<p>Хроническая почечная недостаточность</p>\r\n<p>Для начальной стадии характерно типично латентное течение с полиурией (), никтурией, гипертонией, умеренно выраженной анемией.</p>\r\n<p>Консервативная стадия характеризуется увеличенным мочеиспусканием (полиурией) с преобладанием ночного диуреза (никтурия), слабостью, снижением трудоспособности, потерей массы тела. У большинства больных выявляется гипертония и анемия.</p>\r\n<p>При терминальной стадии полиурия часто сменяется олигурией (уменьшением количества выделяемой мочи). Больные вялы, апатичны. Отмечается резкое снижение аппетита (вплоть до анорексии), сухость и неприятный вкус во рту, частая тошнота. Типичны резкая слабость, зябкость, инверсия сна, кожный зуд, тонические судороги икроножных мышц. Гипертония часто приобретает трудноконтролируемое течение, приводит к резкому снижению зрения, острой левожелудочковой недостаточности с отеком легких. Характерна бледность. Кожа сухая, желтушная с серым оттенком, кровоизлияниями и следами расчесов. Нередко развиваются моноартриты вследствие вторичной подагры, боли в костях и позвоночнике, парестезии и резкая слабость в нижних конечностях (полинейропатия), носовые кровотечения.</p>\r\n<p>При далеко зашедшей уремии обнаруживается запах аммиака изо рта, периодическое дыхание (декомпенсированный метаболический ацидоз), перикардит, уремическая прекома.</p>\r\n<p> </p>",
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},
"code": "N23",
"name": "Почечная колика неуточненная",
"icd_name": "Почечная колика неуточненная",
"gender": 0,
"age_min": 10,
"age_max": 60,
"cause": [
"0"
],
"periodicity": 1,
"slug": "n23_pochechnaya_kolika_neutochnennaya",
"lead": "острый болевой приступ, обусловленный внезапным нарушением пассажа мочи, повышением внутрилоханочного давления",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Почечная колика – состояние, характеризующееся приступом очень резкой боли в области поясницы, которая возникает вследствие затруднения оттока мочи от почки до мочевого пузыря. Из-за затруднения оттока мочи чашечно-лоханочная система почки переполняется мочой, повышается давление в почечных лоханках и нарушается кровообращение в почке.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В подавляющем большинстве случаев блокирование оттока мочи происходит вследствие закупорки мочевых путей конкрементом. Таким образом, в 80-90% причина почечной колики связана с мочекаменной болезнью.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Факторами риска данного состояния являются:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отягощенная наследственность;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">хроническое обезвоживание организма;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">метаболические нарушения;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">подагра;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">аномальное строение мочевыводящих путей.</span></li>\r\n</ul>\r\n<p><strong id=\"docs-internal-guid-3bd6170c-7fff-fbbe-a76a-a40574653b49\" style=\"font-weight: normal;\"> </strong></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Менее распространенными (встречаются в 10% случаев почечной колики) фоновыми патологиями являются:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">воспалительный процесс в чашечно-лоханочной системе почек;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">опухолевый процесс в почке;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">туберкулезное поражение сосочков почки;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">травматическое повреждение органа;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">опухоли рядом расположенных органов, которые оказывают механическое давление извне;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">аллергические и аутоиммунные процессы.</span></li>\r\n</ul>",
"pathogenesis": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В результате нарушения оттока мочи повышается внутрипочечное давление – образно говоря, почку раздувает как шарик с водой. Давление мочи на паренхиму почки приводит к нарушению в ней микроциркуляции, развитию отека. Все это в совокупности воздействует на рецепторы чувствительных нервов ворот и фиброзной капсулы почки, которые имеют небольшой потенциал растяжимости, следствием чего является возникновение характерного приступа боли.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Установление диагноза почечной колики начинается с детальной оценки жалоб пациента. После этого уролог проводит объективный осмотр пациента. Нередко выявляется резкая болезненность в поясничной области, которая усиливается при глубоком надавливании и поколачивании.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Всем пациентам с урологическими жалобами обязательно проводится общеклинический анализ мочи. В случае мочекаменной болезни, которая привела к почечной колике в результатах этого исследования будет выявляться повышенное количество эритроцитов, при воспалительном генезе – повышается содержание лейкоцитов и т.д. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В программу диагностики также входит общеклинический анализ крови, в котором оцениваются воспалительные изменения. Биохимическое исследование плазмы по уровню креатинина, мочевины, натрия и калия дает информацию о функциональном состоянии почек и позволяет исключить почечную недостаточность (грозное осложнение колики).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В обязательном порядке проводятся также инструментальные исследования, которые направлены на визуализацию патологического процесса, в первую очередь возможных конкрементов. Из этих методов могут применяться:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">ультразвуковое сканирование почек и мочевых путей – является скрининговым методом, который дополняется другими исследованиями;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">обзорная рентгенография, а также прицельная с контрастом;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">компьютерная томография – это наиболее чувствительный метод, который позволяет визуализировать практически все типы камней, кроме индинавировых. КТ расценивается как первая линия диагностики.</span></li>\r\n</ul>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Главная задача лечения – это устранение обструкции и нормализация пассажа мочи. Для реализации этой цели в большинстве случаев достаточно консервативной терапии, однако иногда требуется проведение операции.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Консервативное лечение</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основными мероприятиями консервативного лечения, проводимого урологом, являются:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Назначение нестероидных противовоспалительных средств. Эти препараты помогают уменьшать выраженность боли и борются с воспалительным отеком мочевых путей. В современной урологии стараются минимально использовать наркотические анальгетики, которые могут оказывать неблагоприятное системное воздействие. Этот класс применяется только при резистентном болевом синдроме, когда нестероиды оказываются малоэффективными.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Использование спазмолитиков по показаниям. Некоторым пациентам требуется применение препаратов, которые помогают устранить спазм гладкой мускулатуры мочевых путей.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Применение адреноблокаторов, которые помогают выводить камни из мочевых путей. Это направление применяется только, если диаметр конкремента не превышает 7 мм. Поэтому всем пациентам с почечной коликой и проводиться детальное обследование перед началом лечения – оно позволяет узнать точные размеры камней.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">На этапе купирования боли можно принимать теплую ванну. Это дополнительно расслабляет гладкую мускулатуру и может создавать условия для отхождения конкремента.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Всем пациентам с инфекционными осложнениями урологи в индивидуальном порядке подбирают инфузионную и антибактериальную терапию. Для ее коррекции на этапе обследования обязательно проводится бактериологическое исследование мочи с определением чувствительности выделенных возбудителей к антибиотикам.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хирургическое лечение почечной колики</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В осложненных случаях почечной колики требуется немедленно восстановить пассаж мочи. Для этого проводится дренирование мочевых путей через кожу. Показаниями для этой манипуляции являются:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">острый пиелонефрит;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">незначительное выделение мочи или ее полное отсутствие (врачи расценивают такое состояние как недостаточность почек);</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">сепсис – присутствие патогенных микроорганизмов в кровеносном русле.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В некоторых случаях даже при неосложненной почечной колике методом выбора является оперативное вмешательство. Оно заключается в дроблении камней или их контактном извлечении.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Показанием для таких процедур является изначально известная бесперспективность консервативного лечения, т.е. когда уролог сразу понимает, что через естественные мочевые пути камень под действием медикаментов не выйдет.</span></p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Главное направление в предупреждении почечной колики – это своевременное лечение урологических заболеваний, которые могут являться фоном. В первую очередь это касается мочекаменной болезни. Для ее предупреждения рекомендуется:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">употреблять не менее 2 литров воды в сутки (это должна быть вода с минимальной или средней жесткостью);</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">правильно питаться – избегать частого употребления острых и соленых блюд, исключить из рациона копчения и фастфуды;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">своевременно опорожнять мочевой пузырь (при появлении первых позывов к мочеиспусканию).</span></li>\r\n</ul>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Главным признаком почечной колики является приступ острой боли, который появляется внезапно. Болевые ощущения имеют следующие характеристики:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">имеют периоды затихания и периода нарастания интенсивности;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отдают по ходу мочевых путей – боли ощущаются не только в пояснице, но также в боковых отделах живота, паху и наружных отделах половых органов;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отсутствует удобное положение, которое помогает уменьшить выраженность боли (человек буквально мечется в кровати);</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">учащается мочеиспускание, которое иногда может сопровождаться резью и дискомфортом;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">сопутствующие симптомы – тошнота и рвота без облегчения, учащенное сердцебиение, незначительное повышение температурных показателей тела.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">После острого приступа, который может проходить самостоятельно или под действием спазмолитиков, в поясничной области сохраняется неинтенсивная боль тупого характера, при этом самочувствие пациентов в целом удовлетворительное.</span></p>",
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"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В норме система потоотделения человека активно участвует в процессе терморегуляции организма. При повышении температуры окружающей среды активируется работа потовых желез, они начинают интенсивно выделять пот, что способствует некоторому охлаждению кожного покрова и защищает организм от перегревания. Этот же механизм срабатывает при повышении температуры самого тела. Например, при различных заболеваниях, протекающих с лихорадкой (ОРВИ, грипп, острый бронхит, пневмония, ангина, корь, ветряная оспа, краснуха и др.), интенсивной физической активности, тепловых процедурах, применении согревающих компрессов или укутываний.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Интенсивное потоотделение может привести к закупорке потовых желез и возникновению потницы. Особенно часто потница возникает у новорожденных и детей до года, поскольку их потовые железы не до конца сформированы и имеют узкие выводные протоки. Среди взрослых потница встречается чаще у людей с повышенной потливостью, избыточным весом или нарушениями в работе эндокринной системы.</span></p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Перегревание кожи, в том числе при лихорадочном состоянии, и повышенная влажность окружающей среды увеличивают образование пота.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Из-за воздействия причинных факторов (тесной одежды, избыточной массы тела и др.) перекрывается проток эккринных желёз. Закупорка может произойти на разной глубине. Когда проток закрывается, пот не выходит на поверхность тела, а попадает под кожу — в эпидермис или дерму. Из-за этого в клетках накапливается вода, возникает отёк и происходит закупорка протоков. Более глубокое поражение эккринной железы или протока может привести к их разрыву.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гистологическая картина кожных проявлений характеризуется перекрытием отверстий протоков эккринных желёз кератиновыми пробками, растяжением этих протоков в эпидермисе и иногда в дерме. Кератиновые пробки формируются, когда из-за повышенного потоотделения нарушается ороговение наружного слоя кожи.</span></p>",
"diagnostics": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагноз потницы обычно не вызывает затруднений у врача любой специализации. Поэтому для подтверждения диагноза достаточно визуального осмотра педиатра или терапевта. В сложных случаях может потребоваться консультация дерматолога.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В лечении потницы основное значение принадлежит устранению перегревания пациента. Этому способствует частое проветривание помещения, воздушные ванны, водные процедуры, ношение менее теплой одежды и хлопчатобумажного белья. Во избежание потницы в жаркое летнее время необходимо использовать охлаждение помещения при помощи вентилятора или кондиционера. Взрослым пациентам с потницей рекомендовано избегать физической активности в жарких условиях или теплой одежде. В подавляющем большинстве случаев симптомы потницы проходят в первые 1-3 дня после прекращения действия вызывающего ее фактора.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для ускорения выздоровления может применяться местное лечение. Хорошо помогают при потнице ванны с раствором перманганата кальция, ромашкой, чередой, после которых участки высыпаний можно обработать присыпкой с оксидом цинком или тальком. При выраженном зуде у взрослых применяют препараты с ментолом и камфорой, бетаметазоновую мазь. Появление инфекционных осложнений при потнице является показанием к местной противомикробной терапии антисептиками и антибиотиками.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Предупреждение потницы заключается в соблюдении гигиены кожи, поддержании оптимальной температуры помещения, регулярных водных процедурах, устранении ситуаций, приводящих к сильному потоотделению. Летом необходимо избегать длительного пребывания на открытом солнце. Для людей, переезжающих в более жаркие климатические условия, желательна постепенная адаптация.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отдельно необходимо сказать об одежде. Непосредственно контактирующее с кожей белье должно быть «дышащим» и не слишком тесным. Важно, чтобы одежда соответствовала погоде и физической активности человека. Так, при занятии спортом или физической работе, а также у подвижных детей одежда должна быть менее теплой.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для профилактики потницы у детей первого года жизни необходимо избегать тугого пеленания и слишком теплого укутывания. Большое значение имеет правильный уход за кожей малыша, регулярное проведение водных процедур и воздушных ванн, хорошее проветривание помещения, использование качественных подгузников, хлопчатобумажной одежды и белья.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Наиболее простой и безопасной формой является кристаллическая потница. Она проявляется небольшими (до миллиметра) безболезненными высыпаниями — это мелкие пузырьки, которые расположены рядом друг с другом и могут сливаться. Локализуются такие высыпания на шее, лице, лбу, туловище, а также в местах сгиба ног, рук. Часто эта потница возникает ненадолго и быстро исчезает при соблюдении привычной гигиены.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Более опасен такой вид потницы, как красная (воспалительная). Ее признаки, следующие:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Высыпания в виде более крупных пузырьков (до двух миллиметров) с красными воспаленными венчиками. В этих пузырьках наблюдается содержимое мутного вида.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Зуд, который может быть довольно сильным и беспокоить пациента неприятными ощущениями.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Мокрые корочки. Если они появились, это означает, что к обычной болезни у взрослого присоединилась бактериальная инфекция — то есть возникло осложнение.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Обычно красная разновидность недуга локализуется подмышками, на животе и коже между ягодицами, а также на сгибах локтя, предплечьях. У людей, страдающих ожирением, она часто появляется в паху. В отличие от предыдущего варианта, этот не проходит самостоятельно и всегда требует целенаправленного лечения.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если течение красной потницы осложняется, может развиться так называемая папулезная форма с острым воспалением. Тут уже появляются не только зуд, но и симптомы интоксикации. Кожа болезненная, состояние больного сложное. Вылечить такое заболевание можно только специально подобранными медикаментами — в ряде случаев для этого требуется не один месяц.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Еще один вариант потницы у взрослых — апокринная. Она связана с работой специальных желез, которые находятся на ареоле соска, в области анального отверстия, подмышками, а также у женщин в области больших половых губ. В этих местах появляется мелкая сыпь, а также специфические скопления в области желез. Эти образования часто лопаются прямо внутри кожи и к ним присоединяется инфекционный процесс. 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}
]
}
