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},
"code": "C57",
"name": "Рак других и неуточненных женских половых органов",
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"description": "Рак маточной трубы наблюдают достаточно редко. По данным мировой и отечественной литературы, встречаемость рака маточной трубы составляет 0,11–1,18% среди опухолей женских половых органов.\r\n\r\n",
"etiology": "<p>Считают, что предрасполагающими факторами, способствующими возникновению рака маточной трубы, служая воспалительные заболевания органов малого таза в анамнезе, <a href=\"/symptom/besplodie/\" title=\"Перейти на страницу симптома Бесплодие\">бесплодие</a>, возраст старше 40 лет. Воспалительные заболевания маточных труб отмечают более чем у 1/3 больных; большинство больных страдают бесплодием (40–71%).</p>\r\n<p>В последние годы появились сообщения, свидетельствующие о возможной вирусной этиологии рака маточных труб.</p>",
"pathogenesis": "<p>На ранних стадиях заболевания маточная труба макроскопически может быть не изменена. При запущенных стадиях она увеличивается в размерах и деформируется, приобретая колбасовидную, ретортообразную, яйцевидную и другие формы.</p>\r\n<p>При запаянном отверстии ампулы маточной трубы внешне характерна картина гидрогематопиосальпинкса. Поверхность опухоли обычно мелкобугристая, мелковорсинчатая, сероватобелого или розоватобелого цвета (напоминает цветную капусту). Большая часть поверхности поражённых маточных труб серосинюшного цвета, иногда темнобагрового, что наблюдают при перекруте трубы с резко выраженной дисциркуляцией. При открытом отверстии ампулы маточной трубы опухолевые массы чаще всего выступают в брюшную полость в виде опухолевых узлов или разрастаний бородавчатого вида.</p>",
"diagnostics": "<p>Правильная предоперационная диагностика рака маточной трубы крайне неинформативна (всего 10%). Даже интраоперационно правильный диагноз устанавливают только в 50% случаев. Следует подчеркнуть, что ни одна деформация маточной трубы не должна быть оставлена во время операции без обследования (исследовать следует весь операционный материал).</p>\r\n<p>Учитывая отсутствие высокоинформативного метода диагностики, большинство клиник применяют комплексный подход, включающий целый ряд клинических, лабораторных и инструментальных методов исследования. Среди них наиболее часто выполняют УЗИ и рентгеновскую КТ, лапароскопию, определение опухолеассоциированных маркёров.</p>",
"treatment": "<p>Первым этапом при раке маточной трубы проводят хирургическое лечение — выполнение радикальной операции, включающей экстирпацию матки с придатками, удаление большого сальника, биопсию парааортальных и подвздошных лимфатических узлов, биопсию и взятие смывов с брюшины таза, латеральных каналов и диафрагмы. При невозможности выполнения лимфаденэктомии выполняют биопсию этих узлов.</p>\r\n<p>Выборочные исследования и широкое применение различных химиопрепаратов, их комбинации, а также сочетание химиотерапии с лучевой терапией не позволяют провести адекватное сравнение различных подходов лечения. Высокая частота неэффективности лечения даже при ранних стадиях подчеркивает необходимость адъювантного лечения на каждой стадии заболевания.</p>",
"prevention": "<p>Профилактика рака маточной трубы мало изучена и сводится к своевременному лечению воспалительных процессов.</p>",
"clinical_picture": "<p>В отличие от рака яичников, в большинстве случаев характеризующегося долгим бессимптомным течением, при раке маточных труб существует достаточное разнообразие симптомов. Наиболее частыми симптомами бывают обильные водянистые и кровянистые выделения, боли внизу живота. Однако сочетание этих трёх признаков отмечают лишь в 12,5% случаев.</p>\r\n<p>Кровянистые выделения из половых путей на фоне менопаузы или ациклические кровянистые выделения у женщин репродуктивного возраста отмечают в 50–60% случаев. Кровянистые выделения преимущественно обусловлены прорастанием слизистой оболочки маточной трубы опухолью, а также распадом опухоли. В этом случае часто ошибочно ставят диагноз рака эндометрия и более чем в половине случаев производят диагностическое выскабливание матки (иногда повторно). Даже в повторно произведённых соскобах не всегда обнаруживают опухолевую ткань. Это приводит к задержке в постановке истинного диагноза.</p>\r\n<p>Подозрение на рак маточных труб вызывают также обильные, периодически возникающие водянистые выделения (иногда с примесью крови), совпадающие с уменьшением мешотчатой опухоли придатков матки. Этим выделениям предшествуют схваткообразные боли внизу живота. Симптом «перемежающейся водянки» маточной трубы считают патогномоничным для рака маточной трубы (наблюдают в 3–14% случаев).</p>\r\n<p>Метастатическое поражение лимфатических узлов (парааортальных, надключичных, шейных) может быть первым клиническим признаком рака. Такую клиническую картину наблюдают в 8–12,5% случаев. К объективным симптомам рака маточных труб относят <a href=\"/symptom/uvelichenie_zhivota/\" title=\"Перейти на страницу симптома Увеличение живота\">увеличение живота</a> в объёме вследствие скопления свободной жидкости в брюшной полости у больных с III и IV стадией заболевания или вследствие роста опухолей.</p>",
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},
"code": "C17.0",
"name": "Рак двенадцатиперстной кишки",
"icd_name": "Рак двенадцатиперстной кишки",
"gender": 0,
"age_min": 60,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "c17.0_rak_dvenadcatiperstnoy_kishki",
"lead": "злокачественное новообразование, формирующееся из клеток эпителиальной ткани кишки",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рак двенадцатиперстной кишки — это злокачественная опухоль в начале тонкого кишечника, куда поступает содержимое желудка и открывается проток для желчи и секрета поджелудочной железы. </span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К развитию онкологических новообразований в области ДПК приводит:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Дуоденит;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Язвенная болезнь;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Болезнь Крона;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Хеликобактерная инфекция;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Иммунодефицит.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Включая хронические заболевания поджелудочной железы и вирусные инфекции.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Способствовать развитию рака тонкого кишечника, также могут:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Нарушенный рацион питания (жирная мясная еда, недостаток клетчатки);</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Наследственный фактор;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Вредные привычки (этанол, табачные смолы неблагоприятно воздействуют на работу ЖКТ);</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Ожирение;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Малоподвижный образ жизни.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Люди, которые злоупотребляют глютеном и красным мясом, в два раза больше рискуют заболеть раком кишечника.</span></p>",
"pathogenesis": "",
"diagnostics": "<p>Диагностика рака ДПК предусматривает следующие мероприятия:</p>\r\n<ul>\r\n<li>сбор анализа, осмотр пациента,</li>\r\n<li>лабораторные исследования (общий и биохимический анализ крови, анализ на онкомаркеры, анализ мочи),</li>\r\n<li>ЭФГС (эзофагогастродуоденоскопия),</li>\r\n<li>биопсия с дальнейшим гистологическим исследованием (проводится во время ЭФГС),</li>\r\n<li>рентгенография с контрастным веществом,</li>\r\n<li>магнитно-резонансная томография (МРТ),</li>\r\n<li>компьютерная томография (КТ).</li>\r\n</ul>\r\n<p><span id=\"docs-internal-guid-bda54d75-7fff-9b95-4232-983f273cd23a\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Для определения наличия метастаз может назначаться рентгенография грудной клетки, УЗИ органов брюшной полости и др.</span></span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">К современным методам лечения рака тонкого кишечника относятся:</span></p>\r\n<ul style=\"margin-top: 0px; margin-bottom: 0px; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Химиотерапия.</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Лучевая терапия.</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">HIPEC-терапия (внутрибрюшная химиотерапия), в отдельных случаях.</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Оперативное вмешательство (удаление пораженного участка).</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">К профилактике онкозаболевания можно отнести:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">полноценное питание,</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отказ от крепких спиртных напитков и табакокурения,</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">своевременное лечение воспалительных и других заболеваний желудочно-кишечного тракта,</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">регулярные обследования у врача, особенно лицам старше 50 лет.</span></li>\r\n<li></li>\r\n</ul>\r\n<p> </p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Типичные симптомы рака двенадцатиперстной кишки практически не выявляются на ранних стадиях. Заболевание достаточно длительное время может протекать бессимптомно. Определить опухоль в это время можно случайно, при проведении обследований по поводу других заболеваний. В более поздней стадии возможны боли при раке двенадцатиперстной кишки. Но и они не всегда настораживают пациента, так как могут быть приняты за признаки несварения или переедания. Боль имеет тупой и разлитой характер, обычно она локализуется в верхней части живота, под ребрами или подложечкой. Возможно появление болезненных ощущений в ночные часы или после длительного голодания. По мере прогрессирования болезни может возникать интоксикация продуктами распада опухоли. Это проявляется потерей веса, резкой бледностью, постоянной слабостью.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Проявления рака во многом зависят от стадии рака, размера очага и дополнительных патологий, осложняющих состояние. На поздних стадиях рак может себя проявлять следующими признаками:</span></p>\r\n<ul style=\"margin-top: 0px; margin-bottom: 0px; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">апатия, депрессия, слабость с быстрой утомляемостью, заторможенностью;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">нарушения сна с сонливостью или бессонницей;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">головокружения и головная боль;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">резкое снижение аппетита, что приводит к резкому похудению, потере до 10% веса и более;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">бледность кожи с восковым или синюшным оттенком, желтизна склер;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">сухость слизистых рта, глаз и носа;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">постоянная субфебрильная температура;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">потливость в ночные часы;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">стойкая анемия;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">тошнота, приступы рвоты, дискомфорт в животе;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7.5pt; font-family: Verdana; color: #212529; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">частые простуды, снижение иммунитета.</span></p>\r\n</li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Если ткань опухоли распадается, повреждаются сосуды и открывается кровотечение, возможно появление черного стула.</span></p>",
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"code": "C50",
"name": "Рак груди",
"icd_name": "Рак молочной железы",
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"lead": " это заболевание, вызванное перерождением нормальных клеток железистой ткани в раковые. ",
"description": "Рак груди развивается так же, как и любая другая злокачественная опухоль в организме. Одна или несколько клеток железистой ткани в результате произошедшей в них мутации начинают аномально быстро делиться. Из них образуется опухоль, способная прорастать в соседние ткани и создавать вторичные опухолевые очаги.",
"etiology": "<p>1. Генетическая предрасположенность.Онкология молочной железы чаще всего возникает у женщин, чьи родственники были подвержены тому же заболеванию. Прежде всего, речь идет о матери и/или сестре, если она есть. В случае, если рак у одной из ближайших родственниц был выявлен, диагностику онкологии стоит проводить с раннего возраста.</p>\r\n<p>2. Начало менструаций до 12 лет и прекращение после 55 лет.Согласно статистике, наиболее часто рак молочной железы возникает у женщин с высоким уровнем эстрогенов. Чем дольше длятся менструальные циклы, тем больше и уровень женских гормонов и тем выше риск. Отсутствие родов и беременностей можно отнести к тому же фактору риска.</p>\r\n<p>3. Наличие рака половых органов (в том числе вылеченного).Прямая связь между женскими половыми органами и молочной железой делает свое дело: злокачественная опухоль шейки матки, матки и других органов чаще всего вызывает и рак груди.</p>\r\n<p>4. Курение, злоупотребление алкоголем.Канцерогены, содержащиеся в алкоголе и продуктах горения табака, снижают защитные силы организма и способны привести к раку. К подобным факторам можно отнести и радиационное воздействие, плохую экологическую обстановку в регионе и т.д.</p>\r\n<p>5. Сахарный диабет, , .</p>\r\n<p>6. Прием экзогенных гормонов на протяжении 10 лет и более.Выявлено, что при длительном употреблении подобных препаратов для контрацепции или в терапевтических целях риск появления рака выше.</p>\r\n<p>7. Травмы, мастит.Более высокий риск - у тех, кто перенес заболевание или травму молочной железы.</p>\r\n<p>Даже если нет ни одного фактора риска из перечисленных выше, полностью исключить вероятность возникновения этого заболевания невозможно.</p>",
"pathogenesis": "",
"diagnostics": "<p>Для подтверждения или исключения диагноза в первую очередь проводится мануальное обследование груди. Затем, при наличии подозрений или в качестве скрининговой процедуры, может быть назначена маммография, рентгенологическое исследование молочных желез. Как правило, женщинам до 35 лет ее выполнение не рекомендуется, в молодости ткань молочных желез особенно чувствительна к радиоактивному облучению. Ультразвуковое исследование (УЗИ) молочных желез позволяет оценить структуру их ткани и отличить, например, опухоль от кисты, наполненной жидкостью. Если результаты маммографии или УЗИ указывают на наличие новообразований в молочной железе, врач, как правило, назначает биопсию, лабораторное исследование образца тканей из молочной железы. Биопсия позволяет выяснить, является ли опухоль злокачественной, а также определить ее тип и стадию. Кроме того, исследование биопсийного материала дает ответ на вопрос, является ли опухоль гормонозависимой, что также влияет на схему лечения. При необходимости могут использоваться и другие диагностические методы, например, магнитно-резонансная томография (МРТ). После постановки диагноза основной задачей лечащего врача является определение стадии онкологического заболевания, то есть размера опухоли, ее расположения, наличия метастазов и агрессивности. От этих факторов зависит прогноз лечения и подбор оптимальных методов терапии. Как правило, для уточнения стадии проводятся анализы крови, маммография другой молочной железы, сканирование костей, а также компьютерная или позитронно-эмиссионная томография. В некоторых случаях определить стадию опухоли можно только при проведении операции.<br /><br /><br /></p>",
"treatment": "<p>Если симптомы при онкологии молочной железы подтвердили ваши подозрения, вам необходимо сразу же приступить к лечению в онкологической клинике. Запускать это . Промедление может оказаться чрезвычайно опасным и привести к смерти в течение нескольких лет.</p>\r\n<p>На данный момент существуют следующие типы лечения:</p>\r\n<p>1. Оперативное (радикальное)</p>\r\n<p>Это лечение направлено на полное удаление опухоли во время операции. Хирургическое вмешательство - единственный способ полностью излечить данное заболевание. Но и оно не всегда дает положительный результат: многое зависит от характера и стадии рака.</p>\r\n<p>2. Вспомогательное (условно радикальное)</p>\r\n<p>Эти методы терапии могут применяться до, во время и после операции, либо, в редких случаях, вместо нее. К ним относятся лучевая терапия, химиотерапия, таргетная и иммунотерапия.</p>\r\n<p>3. Паллиативное</p>\r\n<p>Если диагностика онкологии была проведена слишком поздно, либо вы запустили болезнь, даже полное удаление груди не подарит здоровье. При отказе от операции, наличии метастазирования, которое уже невозможно остановить, онкологу остается назначить паллиативное лечение. Оно снимет симптомы и поможет продлить жизнь.</p>\r\n<full></full>\r\n<p>Радикальные методы лечения онкологии молочной железы</p>\r\n<p>Несколько десятилетий назад для лечения данного заболевания требовалось полное удаление груди. Это вынуждало многих отказываться от наиболее эффективной терапии. На данный момент полное удаление не всегда требуется: появились новые типы операций и новое оборудование, позволяющее сохранить грудь хотя бы частично.</p>\r\n<p>1. Лампэктомия</p>\r\n<p>Этот тип операции подразумевает под собой удаление самой опухоли. Проводится при условии, что опухоль есть только в одной области и не имеет больших размеров (до 4 см). После лампэктомии грудь сохраняет свою форму и чувствительность. После операции необходимо пройти лучевую терапию (5-7 недель). К сожалению, лампэктомия не исключает рецидивы - возникают они чаще, чем после других операций.</p>\r\n<p>2. Радикальная секторальная резекция по Блохину</p>\r\n<p>Этот тип операции позволит сохранить грудь, но не ее форму и размеры: удаляется от 33 до 25% тканей, включая малую грудную мышцу, а также ткани (лимфоузлы и клетчатку) в областях под мышкой, под лопаткой, под ключицей. Последнее необходимо, чтобы позднее исключить развитие метастаз, если рак молочной железы возникнет снова.</p>\r\n<p>3. Мастэктомия</p>\r\n<p>Радикальная мастэктомия подразумевает полное удаление молочной железы и некоторых других тканей. Подобная операция исключает рецидивы (в большинстве случаев). Дает эффект в случае, если нет метастаз. Впрочем, и при их наличии мастэктомия позволяет продлить срок жизни пациента, улучшить ее качество. Косметический эффект от мастэктомии довольно серьезный, но это единственный способ сохранить жизнь при крупных опухолях.</p>\r\n<p>Помимо традиционного хирургического вмешательства могут использоваться и дополнительные методики: криомаммотомия и абляция (лазерная, радиочастотная и т.д.). Эти методики позволяют провести операцию женщинам, имеющим противопоказания к хирургическому вмешательству (например, пациенткам с сахарным диабетом). В этом случае возможно более успешное и менее травматичное лечение рака молочной железы, но также не исключены рецидивы.</p>\r\n<p class=\"title\">Условно радикальное лечение рака молочной железы</p>\r\n<p>Условно радикальным называют лечение, требующее длительной реабилитации и имеющее достаточно высокую эффективность. К таким методам относят:</p>\r\n<p>1. Лучевую терапию. Радиационное облучение применяют исключительно в качестве дополнения к операции. Во время процедуры уничтожаются раковые клетки непосредственно на месте опухоли. Главная задача такой терапии – исключить рецидивы после операции.</p>\r\n<p>2. Химиотерапия. Подразумевает под собой прием химических препаратов, оказывающих негативное воздействие на раковые клетки. Это яды и токсины, которые имеют побочное действие и вместе с клетками опухоли уничтожают и клетки крови и тканей организма, которые могут быть чувствительны к тому или иному препарату. Выпускаются химиопрепараты в форме таблеток или растворов для внутривенного переливания. Химиотерапия проводится периодически, в несколько этапов. Применяются и до, и после операции, иногда заменяют собой хирургическое вмешательство. После химиотерапии организм может восстановиться в течение нескольких месяцев.</p>\r\n<p>3. Таргетная терапия. Направлена на блокировку гена HER2, если его активность вызывает рост раковой опухоли. Препараты позволяют замедлить рост опухоли или предотвратить рецидив после операции. </p>\r\n<p>4. Иммунотерапия. Метод задействует собственные защитные механизмы организма пациента. Стимулируя иммунитет, препараты помогают в ликвидации раковых клеток. Сама по себе иммунотерапия недостаточно эффективна, поэтому ее используют только в сочетании с другими методами (например, с химическими препаратами.)</p>\r\n<p>Онкология молочной железы, лечение которой было проведено только условно радикальными методами, чаще всего возникает снова, даже если результат оказался удачным. На данный момент эти методы используют в большинстве случаев как вспомогательные. Также с помощью химио- и лучевой терапии можно задержать рост метастаз.</p>\r\n<p class=\"title\">Паллиативное лечение</p>\r\n<p>Паллиативным называют лечение, направленное на облегчение страданий пациента, которого невозможно вылечить полностью. Применяют сильнодействующие анальгетики, операции, направленные на удаление очага рака молочной железы, препараты, усиливающие иммунитет и устраняющие симптомы. Назначается такое лечение на последних стадиях рака.</p>",
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"clinical_picture": "<p>Признаки онкологии молочной железы достаточно специфичны: в груди появляется небольшое , как правило, безболезненное и не меняющее размеры и плотность в течение месяца. Это можно прощупать самостоятельно.</p>\r\n<p>Обратите внимание на:</p>\r\n<ul>\r\n<li>форму соска: если сосок \"втянулся\", стал меньше, это может говорить об онкологическом заболевании;</li>\r\n<li>форму груди: сохранилась ли она, нет ли неровностей, которые можно принять за ;</li>\r\n<li>структуру молочных желез: прощупываются ли какие-то уплотнения;</li>\r\n<li>размеры лимфатических узлов под мышками: их увеличение - частый симптом онкологии;</li>\r\n<li>цвет кожи;</li>\r\n<li>собственные ощущения: болит ли грудь, испытываете ли вы неприятные ощущения в течение всего менструального цикла.</li>\r\n</ul>\r\n<p>Самостоятельная диагностика онкологии молочной железы не займет много времени. Во время проверки встаньте перед зеркалом, поднимите руки над головой, взгляните на грудь. О наличии уплотнений могут говорить характерные \"ямки\" на коже.</p>\r\n<p>Если вы обнаружили , если один из сосков или оба начали кровоточить, если изменилась форма соска или груди, появились неприятные ощущения, необходимо срочно посетить маммолога, который сможет точно определить, есть ли у вас онкологическое заболевание.</p>",
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}
]
}
