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},
"code": "J35",
"name": "Хронические болезни миндалин и аденоидов",
"icd_name": "Хронические болезни миндалин и аденоидов",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
4
],
"periodicity": 4,
"slug": "j35_hronicheskie_bolezni_mindalin_i_adenoidov",
"lead": "Нарушение здоровья, относящееся к группе другие болезни верхних дыхательных путей",
"description": "Хронические болезни миндалин и аденоидов бывают воспалительного и невоспалительного характера. При этом к воспалительным относят хронические тонзиллиты (поражение небных миндалин) и аденоидит (поражение глоточной миндалины), к невоспалительным – патологическая гипертрофия небных и трубной (аденоиды) миндалин.",
"etiology": "<p>Хронический тонзиллит может быть вызван различными инфекциями. Среди патогенов при хроническом тонзиллите наиболее часто обнаруживают стафилококки, стрептококки, пневмококки, гемофильную палочку, моракселлу, аденовирусы, вирус Эпштейна — Барр, вирусы Коксаки, вирус герпеса, различные анаэробы, микоплазмы, хламидии, грибы.</p>\r\n<p>Основным этиологическим фактором в развитии хронического тонзиллита является бета-гемолитический стрептококк группы А. У большинства больных хроническим тонзиллитом бета-гемолитические стрептококки встречаются в ассоциации с золотистым стафилококком.</p>\r\n<p>Существует наследственная предрасположенность к разрастанию небной и носоглоточной миндалин, обусловленная отклонением в строении эндокринной и лимфатической системы (лимфатико-гипопластический диатез). Располагающими к гипертрофии лимфоидной ткани факторами могут быть возрастная несовершенность иммунологических процессов, воспалительные заболевания глотки, различные детские инфекционные заболевания и повышенная аллергизация детского организма в связи с частыми острыми респираторно-вирусными заболеваниями, эндокринные нарушения, гиповитаминозы, аномалии конституции, грибковая инвазия, неблагоприятные социальные и бытовые условия, радиационное и другие виды воздействия, снижающие реактивность организма.</p>",
"pathogenesis": "<p>Общепринятой теории патогенеза хронического тонзиллита и хронического аденоидита не существует. Основное значение имеет наличие патогенной микрофлоры в лакунах небных миндалин (Streptococcus pyogenes группы А, Haemophilus influenzae, Streptococcus pneumonia и аденовирусов). Особенности строения небных миндалин, имеющих глубокие извитые лакуны, проникающие в толщу паренхимы, создают условия для длительного контакта ткани миндалин с чужеродными белками и токсинами патогенных микроорганизмов. После перенесенных ангин возникают спайки и сращения, которые перекрывают просвет лакун и препятствуют удалению их содержимого — остатков пищи, слущенного эпителия и микроорганизмов. На фоне изменений иммунной реактивности организма это приводит к стойкой воспалительной реакции в небных миндалинах, хронической интоксикации и сенсибилизации (аллергия к антигенам S. pyogenes группы А выявляется у 83% больных хроническим тонзиллитом), вызывающей развитие системных инфекционно-аллергических заболеваний с поражением сердца, сосудов, суставов, почек и др.</p>\r\n<p>В основе механизма развития аденоидов лежит повторное усиление функциональной активности глоточной миндалины под влиянием часто повторяющихся местных воспалительных изменений при различных инфекционных заболеваниях, особенно протекающих на фоне аллергии и при несовершенстве иммунологических процессов у детей младшего возраста.</p>",
"diagnostics": "<p>Диагностика тонзиллита проводится с помощью следующих методов:</p>\r\n<ul>\r\n<li>осмотр ЛОР-врача, сбор анамнеза заболевания;</li>\r\n<li>мазок из глотки на флору с определением чувствительности к антибиотикам и бактериофагам;</li>\r\n<li>общий анализ крови, общий анализ мочи;</li>\r\n<li>анализ крови на антистрептолизин -О, ревматоидный фактор, С-реактивный белок;</li>\r\n<li>ЭКГ;</li>\r\n<li>По показаниям, УЗИ почек, Эхо-КГ, консультация кардиолога, уролога.</li>\r\n</ul>\r\n<p>Диагностика аденоидов:</p>\r\n<p>Ребенка с гипертрофированной глоточной миндалиной узнают по характерному внешнему виду. Размеры и консистенцию аденоидов определяют при задней риноскопии, фиброэндоскопии и с помощью пальцевого исследования носоглотки. Степень аденоидных разрастаний уточняют при боковой рентгенографии полости носа и носоглотки.</p>\r\n<p>Непосредственный детальный осмотр носоглотки проводят методом задней риноскопии, при которой аденоидные вегетации визуализируются как образования неправильной формы с широким основанием, расположенные на своде носоглотки Видно слизистое отделяемое, заполняющее носоглотку и носовые ходы, набухание или гипертрофия носовых раковин. После анемизации слизистой оболочки полости носа, во время фонации при передней риноскопии можно увидеть, как аденоидные разрастания перемещаются по задней стенке глотки. Характерно ограничение подвижности мягкого неба.</p>\r\n<p>Эндоскопический метод — «золотой стандарт» в диагностике аденоидов, проводится как через нос —так и через полость рта.</p>\r\n<p>Диагностика гипертрофии небных миндалин</p>\r\n<p>Диагноз «гипертрофия небных миндалин» ставится на основании жалоб пациента и фарингоскопии или УЗИ области глотки. При фарингоскопии видно, что миндалины увеличены, бледно-розового цвета, мягкие, но воспаления нет. Также делают общий анализ крови.</p>",
"treatment": "<p><strong>Лечение хронического тонзиллита включает:</strong></p>\r\n<p>Консервативную терапию с сохранением самой лимфоидной ткани миндалин как иммунного органа. Терапия включает промывание миндалин и орошение горла растворами антисептиков, ингаляции, системную антибактериальную терапию и иммуностимуляцию. При выборе антибактериального препарата первостепенное значение имеет чувствительность к нему типичных возбудителей. Растущая резистентность различных микроорганизмов ко многим основным антибиотикам является главной проблемой при лечении бактериальных инфекций.</p>\r\n<p>Курсы консервативного лечения обычно проводят 2 раза в год, лучше весной и осенью. При частых рецидивах ангин число курсов консервативного лечения может быть доведено до четырех в год.</p>\r\n<p>Хирургическое лечение: радикальный метод лечения хронического тонзиллита. Характеризуется полным или частичным удаление миндалин, назначается в случае неэффективности консервативного лечения либо при наличии серьезных осложнений со стороны внутренних органов либо при переходе тонзиллита в декомпенсированную форму, когда миндалины перестают выполнять свои функции и превращаются исключительно в хронический очаг инфекции.</p>\r\n<p><strong>Лечение аденоидов</strong></p>\r\n<p>Консервативный способ лечения аденоидов у детей:</p>\r\n<p>Консервативное лечение назначается ребёнку с аденоидитами (с хроническим воспалением аденоидов). Детям с предрасположенностью к разрастанию аденоидов прописывается:</p>\r\n<ul>\r\n<li>промывания носа и носоглотки;</li>\r\n<li>особая диета;</li>\r\n<li>особый климат;</li>\r\n<li>лечение различными фитосборами;</li>\r\n<li>ароматерапия;</li>\r\n<li>массаж различных зон, связанных с данной особенностью;</li>\r\n<li>занятия дыхательной гимнастикой</li>\r\n<li>местные глюкокортикоиды в нос</li>\r\n</ul>\r\n<p>Если данные способ лечения неэффективен, то врач назначает хирургическое лечение</p>\r\n<p>Хирургическое лечение:</p>\r\n<p>Причиной для удаления аденоидов является увеличение более второй степени (если они закрывают просвет носоглотки больше чем на две трети) и связанное с этим нарушение носового дыхания, а также искривление перегородки носа, воспалительный или аллергический отёк слизистой оболочки носовых раковин (наиболее частые), полипоз, новообразования полости носа (более редкие).</p>\r\n<p>Кроме того, аденоиды удаляют при закрытии ими выводного соустья евстахиевых труб и связанного с этим нарушения дренажной функции евстахиевой трубы. При этом из среднего уха не выходит слизь, которая там в норме образуется, и скопление этой слизи нарушает проведение звуков, в результате чего нарушается слух.</p>\r\n<p> <strong>Лечение гипертрофии небных миндалин</strong></p>\r\n<p>При начальных формах гипертрофии достаточно полосканий горла, прижиганий, санаторно-курортного лечения, климатотерапии. Особенно хорошо действует на миндалины морской и горный воздух. Часто назначают кислородные коктейли и физиотерапию: УВЧ на подчелюстные узлы, электрофорез грязевых растворов на подчелюстную область.</p>\r\n<p>При II и III стадиях заболевания, если у ребенка есть трудности с дыханием и глотанием пищи, проводят тонзилэктомию (частичное удаление миндалин). Операцию проводят амбулаторно, под местным обезболиванием.</p>",
"prevention": "<p>Профилактика обострений хронического тонзиллита:</p>\r\n<ul>\r\n<li>Общегигиенические мероприятия;</li>\r\n<li>Закаливание;</li>\r\n<li>Рациональное питание;</li>\r\n<li>Соблюдение правил гигиены жилища и рабочих помещений;</li>\r\n<li>Устранение запылённости, загазованности воздуха;</li>\r\n<li>Санационные мероприятия: выявление и лечение заболеваний дёсен и зубов, синуситов, отитов, нарушений носового дыхания.</li>\r\n</ul>\r\n<p> В качестве профилактики гипертрофии небных миндалин и аденоидов можно порекомендовать закаливание детей, правильное рациональное питание, активный образ жизни. Детям с первой стадией заболевания нужно периодически проходить осмотр у оториноларинголога.</p>",
"clinical_picture": "<p>Для хронического тонзиллита характерно: </p>\r\n<ul>\r\n<li>покраснение и валикообразное утолщение краёв нёбных дужек.</li>\r\n<li>рубцовые спайки между миндалинами и небными дужками.</li>\r\n<li>разрыхленные или рубцово-измененные и уплотненные миндалины.</li>\r\n<li>творожисто-гнойные пробкиили жидкий гной в лакунах миндалин.</li>\r\n<li>увеличение и болезненность поднижнечелюстных (чаще) и шейных лимфоузлов;</li>\r\n<li>боль в горле;</li>\r\n<li>неприятные ощущения в глотке, боль при глотании;</li>\r\n<li>боль в мышцах, суставах;</li>\r\n<li>слабость, вялость, быстрая утомляемость;</li>\r\n<li>субфебрильная температура.</li>\r\n</ul>\r\n<p>Для гипертрофии небных миндалин характерно:</p>\r\n<ul>\r\n<li>затруднение дыхания, глотания;</li>\r\n<li>затруднение речи;</li>\r\n<li>храп ночью;</li>\r\n<li>частые простудные заболевания;</li>\r\n<li>рефлекторный кашель.</li>\r\n</ul>\r\n<p>Для аденоидов характерно:</p>\r\n<ul>\r\n<li>заложенность носа; </li>\r\n<li>затруднение носового дыхания, глотания; </li>\r\n<li>постоянные насморки; </li>\r\n<li>гнусавость;</li>\r\n<li>храп ночью;</li>\r\n<li>обструктивная остановка дыхания во сне;</li>\r\n<li>частые простудные заболевания;</li>\r\n<li>быстрая утомляемость;</li>\r\n<li>частые отиты;</li>\r\n<li>снижение слуха.</li>\r\n</ul>",
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},
"code": "N18",
"name": "Хроническая почечная недостаточность",
"icd_name": "Хроническая почечная недостаточность",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
"0",
"3"
],
"periodicity": 3,
"slug": "n18_hronicheskaya_pochechnaya_nedostatochnost",
"lead": "внезапное или постепенное, частичное или полное угасание фильтрационной, секреторной и выделительной функций почек",
"description": "<p><span id=\"docs-internal-guid-0f389a65-7fff-742f-3319-86405b95b3c8\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Почечная недостаточность — состояние, при котором одна или обе почки не могут в полном объеме выполнять свои функции. </span></span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хроническая почечная недостаточность развивается в результате разрушения тканей почки. Произойти это может из-за следующих причин:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Различных патологий почек – пиелонефрита, гломерулонефрита и других;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Сердечно-сосудистых заболеваний, сопровождающихся повышенным АД;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Заболеваний эндокринного характера;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Токсического поражения организма;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Генетической предрасположенности;</span></li>\r\n<li><span style=\"background-color: transparent; font-size: 7pt; font-family: Verdana; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Опухолей в мочевыделительной системе;</span></li>\r\n<li><span style=\"background-color: transparent; font-size: 7pt; font-family: Verdana; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Системных заболеваний – васкулитов, волчанки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Острой почечной недостаточности.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Особенно осторожными и внимательными к своему здоровью должны быть люди, находящиеся в группе повышенного риска. Необходимо ежегодно проходить обследования, если имеется артериальная гипертензия, сахарный диабет, необходимость принимать лекарства, которые могут навредить почкам.</span></p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хроническая болезнь почек на ранних стадиях описывают как снижение почечного резерва или почечную недостаточность, которая может прогрессировать. Изначально, потеря функции почечной ткани почти не имеет явных патологических проявлений, потому что оставшаяся ткань усиленно работает.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Снижение функции почек коррелирует со способностью почек поддерживать водный и электролитный гомеостаз. На ранних стадиях нарушается способность почек концентрировать мочу, а затем присоединяется снижение способности экскретировать избыток фосфатов, кислоты и калия. При выраженной почечной недостаточности теряется способность эффективно разбавлять или концентрировать мочу.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагностикой ХПН занимается врач-нефролог. Заподозрить наличие болезни можно по снижению скорости клубочковой фильтрации. На первом приеме специалист проводит подробный опрос, который помогает определить симптомы и условия их появления.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Далее диагностика включает:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Общий и биохимический анализ крови;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Общий анализ мочи;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Анализ по Нечипоренко, по Зимницкому;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">УЗИ почек;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эходопплерография;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Биопсия почки;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">ЭКГ, Эхо-КГ.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгеновское исследование с применением контраста проводят редко. Препараты для рентген-диагностики обладают нефротоксичностью, могут вызвать осложнения.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Тактика лечения хронической почечной недостаточности подбирается исходя из причины, спровоцировавшей развитие болезни. Пациентам необходимо постоянно контролировать уровень артериального давления и не допускать его повышения. На ранних стадиях развития ХПН показано медикаментозное лечение. Оно включает прием:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Препаратов эритропоэтина – гормона, который стимулирует образование эритроцитов;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Препаратов железа – показаны при развитии анемии;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">* Витамина Д – улучшает костный обмен, связывает избыток фосфора в крови;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Мочегонные препараты – облегчают работу почек.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Полностью вылечиться от хронической почечной недостаточности невозможно. Основная цель: остановить прогрессирование и не допустить развития осложнений. Очень важно соблюдать диету, которая ограничивает употребление белков, соли и продуктов с высоким содержанием калия. При выраженной дисфункции почек показан гемодиализ либо пересадка органа.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика острой почечной недостаточности заключается в своевременном лечении других заболеваний и по возможности исключения ситуаций-провокаторов (например, отравления ядами или лекарствами). Желательно ежегодно проходить комплексные профилактические обследования и как можно раньше обращаться за медицинской помощью при появлении любых подозрительных симптомов. Важно отказаться от самолечения хронических заболеваний и следовать рекомендациям лечащего врача.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Большинство пациентов с хронической почечной недостаточностью узнают о своей патологии случайно во время планового осмотра. Болезнь может не проявлять себя никакими признаками, симптомы ХПН возникают лишь на запущенных стадиях. Недостаточная работа почек долгое время компенсируется другими органами. Когда функция этого парного органа снижается, возникают следующие признаки:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Тошнота и рвота;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отсутствие аппетита, потеря веса;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Появление одышки, слабости;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отеки по всему телу, в особенности на ступнях и кистях рук;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нарушение сна, спутанность сознания;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кожный зуд, сухость;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Мышечные судороги;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Высокое артериальное давление;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Появление крови в моче;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эректильная дисфункция у мужчин.</span></li>\r\n</ul>\r\n<p> </p>",
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"code": "K72.1",
"name": "Хроническая печеночная недостаточность",
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"lead": "постепенно развивающаяся дисфункция печени, связанная с прогрессирующим течением хронических заболеваний паренхимы",
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"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хроническая печеночная недостаточность развивается постепенно при длительном (хроническом) воздействии гепато-токсических факторов (от 2-х месяцев до нескольких лет). Характеризуется постепенным развитием симптомов на фоне обострения хронических заболеваний печени и желчевыводящей системы.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причины хронической печеночной недостаточности:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хронические гепатиты: вирусные, алкогольный, токсический.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рак печени.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Паразитарные болезни печени: токсокароз, лямблиоз, эхинококкоз.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Аутоиммунные заболевания.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Цирроз печени как в исходе хронического вирусного гепатита, так и посталкогольного генеза или вследствие работы с токсинами, тяжелыми металлами, приема гепатотоксичных препаратов или инъекционных наркотиков.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Паренхиматозная белковая дистрофия, имеющая в основе отложение белка в цитоплазме печеночных клеток. Причины: нарушение белкового обмена, алкоголизм, холестаз, гиповитаминозы, хронические интоксикации в результате приема ядовитых грибов, ядохимикатов и так далее.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Паренхиматозная жировая дистрофия, когда в цитоплазме откладываются триглицериды. Происходит это в результате ожирения, злоупотребления алкоголем, переедания жиров, сахарного диабета, голодания.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Амилоидоз печени. В этом случае в печени откладывается патологический белок-амилоид. Происходит это в результате хронических заболеваний, сопровождающихся интоксикацией.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Паренхиматозная углеводная дистрофия, когда гликоген (много соединенной связями глюкозы) накапливается не в цитоплазмах, а в ядрах печеночных клеток. Причины: нарушение обмена гликогена, сахарный диабет, гипо-и авитаминозы.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для подтверждения диагноза хронической печеночной недостаточности необходимо провести комплекс диагностических мероприятий. Комплекс исследований выглядит так:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Клинический анализ крови — может определяться увеличение количества лейкоцитов, а также снижение количества эритроцитов, тромбоцитов и уменьшение уровня гемоглобина;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Биохимический анализ крови — обращают внимание на уровни билирубина, АЛаТ и АСаТ, щелочной фосфатазы, креатинина;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Коагулограмма — снижение протромбинового индекса крови;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">УЗИ органов брюшной полости — позволяет врачу провести оценку состояния печеночной паренхимы, размеров печени.</span></li>\r\n</ul>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При хронической печеночной недостаточности показано строгое ограничение белка и поваренной соли в рационе питания. Лечение хронической печеночной недостаточности преследует цель устранения аммиачной интоксикации, в связи с чем пациентам назначаются очистительные клизмы и солевые слабительные, антибиотикотерапия (неомицин), лактулоза (подавляет образование аммиака в кишечнике и его всасывание), глутаминовая кислота, и орницетол (для связывания уже всосавшихся токсических продуктов).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">С целью коррекции электролитных нарушений проводят внутривенные инфузии солевых растворов и глюкозы, переливают свежезамороженную плазму. Для поддержания функций печени назначаются гепатопротекторы, витамины группы В, кокарбоксилаза, витамин К, фолиевая кислота. Для снятия интоксикации показаны гемосорбция, плазмаферез, гемодиализ. При прогрессировании хронической печеночной недостаточности ставится вопрос о трансплантации печени.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для того, чтобы значительно снизить риск возникновения хронической печёночной недостаточности, достаточно придерживаться простых правил: отказаться от злоупотребления алкоголем, вести активный и здоровый образ жизни, правильно питаться и следить за весом.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Вакцинация от вирусных гепатитов А и В, а также контроль переливаемой крови, применение одноразовых шприцев и игл в медицинских учреждениях и косметических салонов значительно снижают риск инфицирования.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К наиболее ранним проявлениям хронической печеночной недостаточности относятся диспепсические явления – тошнота, рвота, понос, анорексия. Симптомы нарушения пищеварения часто связаны с употреблением жирной или жареной пищи, копченостей. Может иметь место волнообразная лихорадка, желтуха, поражения кожи (геморрагии, мокнущие и сухие экземы, печеночные ладони). Периферические отеки и асцит при хронической печеночной недостаточности появляются довольно рано.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Особенностью течения хронической печеночной недостаточности служит наличие эндокринных нарушений: бесплодия, снижения либидо, атрофии яичек, гинекомастии, алопеции, атрофии молочных желез и матки.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нервно-психические расстройства при хронической печеночной недостаточности имеют преходящий характер и проявляются депрессией, снижением памяти, чередованием сонливости и бессонницы, беспокойством, периодическими сопорозными состояниями, оглушенностью, потерей ориентации, неадекватным поведением, агрессивностью, раздражительностью и т. п. При неоказании своевременной медицинской помощи может развиваться печеночная кома.</span></p>",
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}
]
}
