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},
"code": "B06",
"name": "Краснуха",
"icd_name": "Краснуха [немецкая корь]",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
"4",
"10"
],
"periodicity": 2,
"slug": "b06_krasnuha",
"lead": "острое, контагиозное инфекционное заболевание человека, вызванное вирусом краснухи, который поражает слизистые оболочки, кожу, лимфатические узлы",
"description": "<p>Краснуха - это <span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">острая инфекция вирусной природы, которая проявляется в виде характерных высыпаний по всему телу кроме ладоней и ступней, а также общей интоксикацией организма умеренной степени на фоне сопутствующего увеличения лимфатических узлов и реакции крови.</span></p>",
"etiology": "<p>Возбудитель краснухи — это <span style=\"border-style: initial; border-color: initial; font-stretch: inherit;\">вирус</span>, содержащий РНК (молекулу рибонуклеиновой кислоты, в состав которой входят все гены возбудителя), относящийся по классификации к семейству Тогавирусов, роду Рубивирусов.<br /> <br />Вирус краснухи имеет размеры 60 – 70 нм, он покрыт белковой оболочкой, на которой имеется некоторое подобие ворсинок — при помощи них возбудитель прикрепляется к клеткам.<br /> <br />Главные характеристики этого возбудителя — способность разрушать и склеивать между собой эритроциты. Для этого у него имеются специальные белки-ферменты. Также в его состав входит фермент нейраминидаза, который поражает нервную ткань.<br /> <br />Во внешней среде вирус краснухи быстро разрушается.<br /> <br />Факторы, которые уничтожают вирус краснухи:</p>\r\n<ul style=\"margin-top: 7px; margin-bottom: 7px; margin-left: 30px; border: 0px; font-stretch: inherit;\">\r\n<li style=\"border: 0px; font-stretch: inherit;\">высушивание;</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\">действие кислот и щелочей (вирус разрушается при уменьшении pH менее 6,8 и увеличении более 8,0);</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\">действие ультрафиолетового излучения;</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\">действие эфиров;</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\">действие формалина;</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\">действие дезинфицирующих средств.</li>\r\n</ul>\r\n<div>Человек может заразиться краснухой только от другого человека. Инфекция передается воздушно-капельным путем (вирус попадает в воздух со слизистой оболочки дыхательных органов больного человека, а затем вдыхается здоровым).<br /> <br />Источники инфекции:<br />\r\n<ul style=\"margin-top: 7px; margin-bottom: 7px; margin-left: 30px; border: 0px; font-stretch: inherit;\">\r\n<li style=\"border: 0px; font-stretch: inherit;\">больные люди, у которых имеется все симптомы заболевания;</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\">больные атипичным(нехарактерным, необычным) течением, у которых нет сыпи и некоторых других симптомов;</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\">дети, больные врожденной формой краснухи (в их организме вирус способен размножаться 1,5 года и более).</li>\r\n</ul>\r\n <br />Заразиться от больного можно только во время последней недели инкубационного периода или в течение недели с того момента, когда на коже у пациента появится <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">сыпь</a>.<br />Если краснухой болеет беременная женщина, то вирус способен передаваться плоду с током крови через плаценту – этот путь передачи называется трансплацентарным.<span style=\"color: #000000; font-family: Arial, Helvetica, sans-serif; font-size: 14px; line-height: normal;\"><br /></span></div>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Входными воротами для вируса краснухи служит эпителий верхних дыхательных путей. Так он внедряется в человеческий организм и локализуется, накапливается и размножается в регионарных лимфоузлах. После вирус прорывается в кровь — появляется вирусемия (распространение вируса по телу). Благодаря эпителиотропным свойствам вируса краснухи, возникают высыпания, длительное пребывание микроорганизмов в лимфоузлах вызывает их гиперплазию, возможно поражение тромбоцитов.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Антитела М класса начинают образовываться и персистировать в кровеносном русле через 1-2 дня с момента начала болезни.</span></p>",
"diagnostics": "<p><span style=\"text-align: justify;\">Диагностическое исследование включает в себя следующие лабораторные анализы: Общий анализ крови (повышенное СОЭ, лимфоцитоз, лейкопения, возможно выявление плазматических клеток). Серологическое исследование носовой слизи (РСК, РИА, ИФА, РТГА). Определение концентрации противовирусных иммуноглобулинов. В обязательном порядке краснуху следует дифференцировать с корью, скарлатиной, энтеровирусной инфекцией и аллергическими высыпаниями.</span></p>",
"treatment": "<p><span style=\"text-align: justify;\">При неосложненной форме краснухи пациентам назначается симптоматическое лечение, которое, как правило, проводится в домашних условиях. Рекомендован постельный режим, обильное питье, для устранения зуда показан прием противоаллергических препаратов. В тяжелых (осложненных) случаях прописывается противовирусная и иммуностимулирующая терапия, а также назначаются патогенетические и симптоматические средства. В данной ситуации необходимо предотвратить развитие отека и набухание головного мозга. Для этого используются кортикостероиды, гемостатики и диуретики. В заключительной стадии (период реконвалесценции) пациентам назначается прием ноотропных препаратов, улучшающих когнитивные (мозговые) функции.</span></p>",
"prevention": "<p>Для предотвращения краснухи применяется вакцина, в состав которой входит живой ослабленный вирус. Основная цель ее применения — предотвращение врожденной краснухи. Инъекции делают будущим мамам – девочкам в возрасте 14 – 15 лет (такая практика принята в России, а в некоторых странах вакцина вводится в возрасте 10 – 14 или даже 9 – 11 лет).<br /> <br />После введения вакцины стойкий иммунитет против краснухи формируется у 95% девочек. Иммунные реакции, которые возникают в организме после прививания, пока еще изучены недостаточно хорошо. Но не известно ни одного случая, когда вакцина становилась бы причиной краснухи у девушки или у ее ребенка в будущем.<br /> <br />Прививка от краснухи практически не имеет осложнений. Лишь у некоторых на ее введение развиваются аллергические реакции.<br /> <br />Противопоказания к прививке:</p>\r\n<ul style=\"margin-top: 7px; margin-bottom: 7px; margin-left: 30px; border: 0px; font-stretch: inherit;\">\r\n<li style=\"border: 0px; font-stretch: inherit;\">у взрослых женщин, так как это может вызвать врожденную краснуху у плода во время беременности;</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\">во время беременности;</li>\r\n<li style=\"border: 0px; font-stretch: inherit;\"><a title=\"Перейти на страницу симптома Эректильная дисфункция\" href=\"/symptom/erektilnaya_disfunkciya/\">не стоит</a> планировать беременность в ближайшие 3 месяца после вакцинации.</li>\r\n</ul>\r\n<div>Если у человека выявлена краснуха, то он должен быть изолирован до того момента, пока не пройдет неделя с момента появления у него сыпи. После этого он становится незаразен.<br />В очаге, где было выявлено заболевание, не нужно проводить дезинфекцию, потому что вирус быстро погибает в окружающей среде.<br /> <span style=\"color: #000000; font-family: Arial, Helvetica, sans-serif; font-size: 14px; line-height: normal;\"><br /></span></div>",
"clinical_picture": "<p>С момента заражения краснухой до появления первых симптомов проходит инкубационный период, который продолжается 11 – 24 суток (у большинства пациентов — 16 – 20 суток). В это время вирус проникает в клетки слизистой оболочки органов дыхания, а оттуда — в кровоток, распространяется с током крови по всему организму, размножается и накапливается.</p>\r\n<p> </p>\r\n<p>Во время инкубационного периода обычно пациентов ничего не беспокоит, они не предъявляют никаких жалоб.</p>\r\n<p> </p>\r\n<p>Симптомы, которые могут возникать во время инкубационного периода краснухи:</p>\r\n<p><a title=\"Перейти на страницу симптома Слабость\" href=\"/symptom/slabost/\">Слабость</a>, <a title=\"Перейти на страницу симптома Утомляемость\" href=\"/symptom/utomlyaemost/\">недомогание</a>, повышенная <a title=\"Перейти на страницу симптома Утомляемость\" href=\"/symptom/utomlyaemost/\">утомляемость</a>, небольшое <a title=\"Перейти на страницу симптома Высокая температура 38-42° \" href=\"/symptom/vysokaya_temperatura_38-42/\">повышение температуры</a> тела (не более 38°С). Это связано с тем, что вирус накапливается в крови и вызывает интоксикацию (<a title=\"Перейти на страницу симптома Острая интоксикация\" href=\"/symptom/ostraya_intoksikaciya/\">отравление</a> вирусными токсинами), со специфическим действием на нервную систему.</p>\r\n<p><a title=\"Перейти на страницу симптома Покраснение кожи\" href=\"/symptom/pokrasnenie_kozhi/\">Покраснение</a> слизистой оболочки глотки. Выявляется во время осмотра горла врачом. Связано с воспалением, которое вызывает вирус, проникая в клетки слизистой оболочки.</p>\r\n<p><a title=\"Перейти на страницу симптома Насморк\" href=\"/symptom/nasmork/\">Насморк</a>, заложенность и выделения из носа. Эти симптомы вызваны воспалением в результате внедрения вируса.</p>\r\n<p><a title=\"Перейти на страницу симптома Покраснение кожи\" href=\"/symptom/pokrasnenie_kozhi/\">Покраснение</a> глаз — возникает при попадании вируса на конъюнктивы.</p>\r\n<p><a title=\"Перейти на страницу симптома Увеличение лимфатических узлов\" href=\"/symptom/uvelichenie_limfaticheskih_uzlov/\">Увеличение лимфатических узлов</a> — они прощупываются в разных местах под кожей. Вирус попадает в них с током крови, накапливается в них и вызывает воспалительный процесс.</p>\r\n<p> </p>\r\n<p>Инкубационный период заканчивается тем, что на теле больного появляется <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">сыпь</a>. За неделю до этого пациент начинает быть заразным.</p>\r\n<p>Типичная (обычная) форма краснухи</p>\r\n<p>Вирус краснухи оказывает токсичное действие на мелкие сосуды, которые находятся под кожей. Из-за этого на теле пациента появляется <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">сыпь</a> красного цвета. В зависимости от состояния больного, выделяют легкую и среднетяжелую форму заболевания. Тяжелая форма характеризуется развитием осложнений.</p>\r\n<p> </p>\r\n<p>Общие симптомы</p>\r\n<p>При легком и среднетяжелом течении краснухи иные симптомы кроме сыпи практически отсутствуют. Человек чувствует себя удовлетворительно. Температура не повышается или не превышает 37 °С. </p>\r\n<p>Сыпь</p>\r\n<p><a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">Сыпь</a> появляется на коже лица и затем распространяется вниз по всему телу. Она состоит из пятен красного цвета, имеющих диаметр 5 – 7 мм и расположенных на гладкой неизмененной коже. Пятна не возвышаются над уровнем кожи. Если надавить на пятно или растянуть кожу, то оно исчезнет, а затем снова появится. Это связано с тем, что пятна вызваны сильным расширением подкожных капилляров. Они всегда сохраняют свои первоначальные размеры и не сливаются между собой. </p>\r\n<p>Нехарактерные разновидности сыпи при краснухе, которые встречаются в отдельных случаях:</p>\r\n<p>крупные пятна, которые имеют размеры 10 мм и более;</p>\r\n<p>папула – возвышение на коже, вызванное воспалительным отеком;</p>\r\n<p>большие пятна с фестончатыми краями — образуются из-за того, что у некоторых пациентов мелкие пятна увеличиваются в размерах и сливаются между собой.</p>\r\n<p><a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">Сыпь</a> при краснухе лучше заметна на туловище, чем на лице. Особенно хорошо она видна в локтевых и подколенных ямках, на ягодицах, верхней части спины, пояснице. Обычно <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">сыпь</a> держится 2 – 3 дня, а потом исчезает. </p>\r\n<p>Если <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">сыпь</a> бледная и плохо заметна, то ее выявляют при помощи «метода манжетки». На руку пациента надевают манжетку от тонометра (прибора для измерения артериального давления) и накачивают ее. Манжетка сдавливает вены, в итоге кровь застаивается в руке, капилляры под кожей расширяются еще больше, <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">сыпь</a> усиливается, и ее можно легко выявить. </p>\r\n<p>Некоторые больные жалуются на то, что их беспокоит <a title=\"Перейти на страницу симптома Зуд\" href=\"/symptom/zud/\">зуд</a> кожи.</p>\r\n<p> </p>\r\n<p>Симптомы со стороны органов дыхания и глаз </p>\r\n<p><a title=\"Перейти на страницу симптома Насморк\" href=\"/symptom/nasmork/\">насморк</a> и выделения из носа – связаны с поражением вирусом слизистой оболочки носа;</p>\r\n<p><a title=\"Перейти на страницу симптома Боль в горле\" href=\"/symptom/bol_v_gorle/\">боль в горле</a> и сухой <a title=\"Перейти на страницу симптома Кашель\" href=\"/symptom/kashel/\">кашель</a> – в результате поражения слизистой оболочки глотки и гортани;</p>\r\n<p><a title=\"Перейти на страницу симптома Слезотечение\" href=\"/symptom/slezotechenie/\">слезотечение</a> резь в глазах – при проникновении вируса в слизистую оболочку конъюнктивы.</p>\r\n<p> </p>\r\n<p><a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">Сыпь</a> на нёбе</p>\r\n<p>На небе у некоторых больных краснухой можно обнаружить мелкие пятна ярко-красного цвета. Они появляются по той же причине, что и <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">сыпь</a> на коже.</p>\r\n<p>Поражение лимфатических узлов, селезенки и печени</p>\r\n<p>С током крови и лимфы вирус краснухи попадает в лимфатические узлы и вызывает в них <a title=\"Перейти на страницу симптома воспаление\" href=\"/symptom/vospalenie/\">воспаление</a>, в результате чего они увеличиваются в размерах. Их можно прощупать под кожей.</p>\r\n<p> </p>\r\n<p>У некоторых больных увеличиваются в размерах печень и селезенка, также из-за того, что в них накапливается вирус</p>",
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5024,
5025,
5026
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},
{
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{
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{
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{
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{
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{
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"lead": "Родинки и изменение цвета кожи требуют наблюдения специалиста",
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},
{
"id": 2848,
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{
"name": "мышечная боль"
},
{
"name": "боль в мышцах"
},
{
"name": "мышцы болят"
},
{
"name": "Миалгия"
},
{
"name": "ломота"
},
{
"name": "боль в мышцах рук"
},
{
"name": "боль в мышцах ног"
},
{
"name": "боль в мышцах после тренировки"
},
{
"name": "боль в мышцах спины"
},
{
"name": "боль икроножная"
}
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"lead": "Мышечная боль, которая периодически возникает у людей при нагрузке или в покое, называется миалгией. Она может вызываться различными причинами и сопровождаться другими симптомами",
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},
{
"id": 2592,
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{
"name": "боль на вдохе"
},
{
"name": "боль при вдохе"
},
{
"name": "болезненный вдох"
},
{
"name": "боль при глубоком вдохе"
}
],
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},
"code": "L93",
"name": "Красная волчанка",
"icd_name": "Красная волчанка",
"gender": 0,
"age_min": 15,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 0,
"slug": "l93_krasnaya_volchanka",
"lead": "диффузное заболевание соединительной ткани, характеризующееся системным иммунокомплексным поражением соединительной ткани и её производных, с поражением сосудов микроциркуляторного русла.",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Красная волчанка – это хроническое мультисистемное воспалительное заболевание соединительной ткани аутоиммунной природы, которое может поражать суставы, почки, кожу, слизистые оболочки и стенки кровеносных сосудов.</span></p>",
"etiology": "<p class=\"disease\">Различают две основные формы: системную красную волчанку (СКВ) и кожную форму (КФ). При кожной форме процесс затрагивает лишь кожные покровы. При СКВ кроме кожи поражаюся так же суставы и внутренние органы («системная» значит, что в патологический процесс вовлечен весь организм). Кожная форма может перейти в системную. Причина возникновения данного заболевания до сих пор остается неясной.</p>\r\n<p class=\"disease\">При СКВ могут поражаться различные органы, поэтому симптоматическая картина чрезвычайно многообразна и варьируется от случая к случаю. Типичным является появление на коже лица высыпании в виде бабочки, кожи к солнцу и ревматоидные поражения суставов.</p>\r\n<p class=\"disease\">В основном болеют женщины детородного возраста (25-35 лет). При этом часто заболевание появляется или во время беременност или непосредственно после нее, что подчеркивает возможную роль женских гормонов (эстрогенов) в развитии заболевания.</p>\r\n<p class=\"disease\">Точные причины заболевания неизвестны. Предполагается, что заболевание является мультифакториальным, то есть вызывается не одной причиной, а их сочетанием.</p>\r\n<p class=\"disease\">Так как красная волчанка во вмногих слуучаях носит семейный характер (как и в случае других аутоиммунных заболеваний), то считается генетически обусловленной, но не наследственной! Генетическая предраспложенность может вызвать развитие болезни только в сочетании с другими факторами.</p>\r\n<p class=\"disease\">К таким факторам относятся:</p>\r\n<ul>\r\n<li>Ультрафиолетовое облучение</li>\r\n<li>Женские гормоны (эстрогены, оральные противозачаточные средства</li>\r\n<li>Возможно, определенную роль в развитии процесса играют инфекции.</li>\r\n</ul>\r\n<p class=\"disease\">СКВ относится к аутоиммунным заболеваниям, то есть иммунная система агрессивно воздействует на собственный организм. В случае красной волчанки поражается кожа и мелкие сосуды различных органов, что вызывает воспалительные процессы.</p>\r\n<p class=\"disease\">Особые формы СКВ:</p>\r\n<ul>\r\n<li>Волчанка, обусловленная приемом медикаментозных препаратов: заболевание протекает в мягкой форме. При ней поражаются суставы и кожа. Симптомы исчезают после отмены приема данных лекарственных средств.</li>\r\n<li>Антифосфолипидный синдром: характеризуется склонностью к артериальным и венозным тромбозам, тромбозы плаценты являются причиной повторяющихся выкидышей.\r\n<p> </p>\r\n</li>\r\n</ul>",
"pathogenesis": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Патогенез связан с нарушением аутоиммунных процессов, в результате чего вырабатываются антитела к здоровым клеткам организма.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">На этапе первичного обращения, пострадавший проходит диагностику, в ходе которой устанавливается характер течения патологии. Обследование обязательно включает лабораторное обследование:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">клинический анализ крови; </span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">анализ на антинуклеарные антитела (АНА); </span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">р</span><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">еакция Вассермана; </span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">тест на ЛЕ-клетки.</span></li>\r\n</ul>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основой лечения служат кортикостероидные гормоны. При этом заболевании они могут наноситься на очаги в виде мазей, вводиться с помощью инъекций непосредственно в очаг пораженной кожи. В тяжелых случаях возможно назначение системных кортикостероидов. В качестве альтернативы или для усиления терапии возможно нанесение на очаги препаратов ингибиторов кальциневрина.</span></p>\r\n<p class=\"disease\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В случаях тяжелого поражения кожи, недостаточном эффекте от наружного лечения проводится системная терапия с использованием антималярийных препаратов (хлорохин, гидроксихлорохин), противовоспалительных препаратов (метотрексат, микофенолат, дапсон, азатиоприн и др.).</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Специфические профилактические рекомендации отсутствуют. Они сводятся к общим правилам:</span></p>\r\n<p> </p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">исключить воздействие стрессов; </span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">избегать продолжительного контакта с прямыми солнечными лучами; </span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">правильно питаться; </span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">заниматься лечением инфекционных и воспалительных заболеваний; </span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">заниматься физкультурой; </span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">отказаться от приема пероральных контрацептивов с повышенной долей эстрогена.</span></li>\r\n</ul>",
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"lead": "Хемоз — отек конъюнктивы, при котором поверхность глаза в области склер заметно увеличивается, может менять цвет и болеть. Такая патология возникает на фоне множества заболеваний глаза, установить точную причину может только врач, поэтому и самолечение в этом случае недопустимо. Особенно опасны ситуации, при которых хемоз возникает часто и склонен к длительному течению. \r\nПричины отека конъюнктивы могут быть острыми и локальными. Среди наиболее частых причин наблюдается: острое воспаление придаточного глазного аппарата и оболочек глаза, укусы насекомых, появление ячменя на глазу, орбитальный целлюлит (воспаление тканей глаза позади орбитальной перегородки), гонорейный конъюнктивит (опасная для зрения патология, которая развивается при гонореи), нарушение микроциркуляции или застой крови, которые могут быть вызваны воздействием или давлением на глаз опухолей орбитальных областей (зона вокруг глазного яблока). Часто при отеке конъюнктивы диагностируется анемия (малокровие), нефрит (воспаление, которое приводит к изменению парных органов), крапивница (кожное заболевание, преимущественно аллергического происхождения).\r\n\r\nПричинами заболевания может быть патологии глаз, черепно-мозговые травмы, бесконтрольное применение медицинских препаратов.",
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{
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},
"code": "L50",
"name": "Крапивница",
"icd_name": "Крапивница",
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"0",
"3"
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"lead": "распространенное прогрессирующее дерматологическое заболевание, которое выражается местным отеком сосочкового слоя дермы или зудящими волдырями с различной степенью выраженности и гиперемии.",
"description": "<p>Крапивница - это <span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">группа заболеваний, характеризующихся развитием зудящих волдырей и/или ангиоотеков.</span></p>",
"etiology": "<p>Причины крапивницы. <br /><br /></p>\r\n<ul class=\"list list-description\">\r\n<li>Пищевые продукты (например, рыба, морепродукты, арахис, яйца, фрукты и др.).</li>\r\n<li>Лекарственные препараты (антибиотики, нестероидные противовоспалительные средства и др.).</li>\r\n<li>Препараты, используемые для диагностических процедур (например, рентгеноконтрастные средства).</li>\r\n<li>Грибковые инфекции (candidaspp., microsporidia).</li>\r\n<li>Бактериальные инфекции (стрептококки и стафилококки, иерсинии, helicobacterpilori, mycoplasmapneumoniae).</li>\r\n<li>Паразитарные болезни:\r\n<ul class=\"list list-description-2\">\r\n<li>шистосомоз (заболевание, вызываемое плоскими червями-сосальщиками, сопровождающееся высыпаниями в местах внедрения, повышением температуры тела, ознобом, поражением кишечника, мочеполовой системы и др.);</li>\r\n<li>трихинеллез (заболевание, вызываемое паразитическими червями, сопровождающееся повышением температуры тела, ознобом, болями в мышцах, отеком лица, высыпаниями на коже, поражением внутренних органов);</li>\r\n<li>описторхоз (заболевание, вызванное плоскими червями, протекающее с повышением температуры тела, недомоганием, слабостью, желтушностью кожных покровов из-за поражения печени и желчного пузыря с протоками);</li>\r\n<li>аскаридоз (заболевание, сопровождающееся субфебрильной температурой тела (повышение до 37,2-37,5° С), болями в животе, тошнотой, потерей аппетита, вялостью, сонливостью, зудом в области ануса) и др.</li>\r\n</ul>\r\n</li>\r\n<li>Вирусные инфекции (например, инфекционный мононуклеоз, вирусы Коксаки, энтеровирусы, парвовирус, норовирус, вирусные гепатиты А и В, вирус герпеса и др.).</li>\r\n</ul>\r\n<p> <br />Факторы, способствующие развитию крапивницы:</p>\r\n<ul class=\"list list-description\">\r\n<li>наличие у больного других заболеваний, в развитии которых имеет место аллергический компонент (например, бронхиальная астма (хроническое аллергическое заболевание дыхательных путей, сопровождающееся приступами удушья), аллергический <a title=\"Перейти на страницу симптома Насморк\" href=\"/symptom/nasmork/\">ринит</a> (<a title=\"Перейти на страницу симптома Насморк\" href=\"/symptom/nasmork/\">насморк</a> с затруднением носового дыхания), атопический дерматит (аллергическое заболевание кожи, лекарственная аллергия));</li>\r\n<li>патология верхних и нижних дыхательных путей, в том числе ОРВИ, назофарингит (<a title=\"Перейти на страницу симптома воспаление\" href=\"/symptom/vospalenie/\">воспаление</a> слизистых оболочек носоглотки с покраснением и отеком);</li>\r\n<li>патология желудочно-кишечного тракта, болезни щитовидной железы;</li>\r\n<li>стрессы (особенно при адренергической и холинергической крапивнице);</li>\r\n<li>опухоли различных органов;</li>\r\n<li>смена климата или места жительства (при солнечной крапивнице);</li>\r\n<li>физические факторы (раздражение кожи, давление, вибрация, физические нагрузки);</li>\r\n<li>температура (при холодовой и тепловой крапивницах).</li>\r\n</ul>\r\n<p> </p>",
"pathogenesis": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Патогенез крапивницы – это сбой в работе иммунной системы. В случае аллергической крапивницы организм реагирует на объективно нейтральное вещество (аллерген), как на вредное, и выделяет белок, называемый гистамином. Когда гистамин высвобождается, крошечные кровеносные сосуды на поверхности кожи (капилляры) воспаляются. Под ними накапливается жидкость, вызывая появление волдырей.</span></p>",
"diagnostics": "<p>Основные лабораторные методы диагностики:</p>\r\n<ul class=\"list list-description\">\r\n<li>общий анализ крови;</li>\r\n<li>биохимический анализ крови;</li>\r\n<li>общий анализ мочи;</li>\r\n<li>анализ крови на гепатиты (гепатит В и гепатит С);</li>\r\n<li>анализ крови на сифилис;</li>\r\n<li>анализ крови на определение уровня общего иммуноглобулина Е(IgE) и специфические IgE к аллергенам;</li>\r\n<li>обследование на наличие паразитов (кал на яйца глист и паразитов, серологическое и молекулярное исследования). </li>\r\n</ul>\r\n<p>Основные инструментальные методы:</p>\r\n<ul class=\"list list-description\">\r\n<li>ультразвуковое исследование (УЗИ) внутренних органов;</li>\r\n<li>фиброгастродуоденоскопия (ФГДС);</li>\r\n<li>электрокардиограмма (ЭКГ);</li>\r\n<li>рентген органов грудной клетки.</li>\r\n</ul>\r\n<p> </p>",
"treatment": "<ul class=\"list list-description\">\r\n<li>Исключение и лечение причины заболевания (если это возможно и причину удалось установить, например, исключить из пищи ароматизаторы, красители и другие пищевые добавки, которые стали причиной заболевания).</li>\r\n<li>Прекращение/уменьшение контакта с провоцирующими факторами (определенные пищевые продукты, порошки и химические средства для мытья посуды и др.).</li>\r\n<li>Антигистаминные препараты действуют на механизм развития аллергии, являются препаратами первой линии в лечении крапивницы (существуют различные формы в виде таблеток, растворов, мазей, гелей, что решается врачом в индивидуальном порядке).</li>\r\n<li>Препараты на основе гормонов (глюкокортикостероиды) применяются в случае отсутствия эффекта от препаратов первой линии короткими курсами (5-7 дней) или при тяжелом течении заболевания с наличием осложнений как наружно, так и системно.</li>\r\n<li>Иммуномодулирующая и иммуносупрессивная терапия (циклоспорин, метотрексат, такролимус).</li>\r\n</ul>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Тем, кто ранее столкнулся с патологией, следует избегать контакта с потенциальными аллергенами. Стоит вести пищевой дневник – записывать ежедневное меню и реакцию организма на продукты.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Людям с лекарственной аллергией для предупреждения крапивницы не рекомендуется принимать препараты на основе ацетилсалициловой кислоты и НПВС.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Одежда из натуральных тканей меньше раздражает кожу и не провоцирует развитие аллергической реакции по типу крапивницы. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Важную роль в профилактике заболевания играют выявление и санация хронических очагов инфекции, глистных инвазий, восстановление нормальной микрофлоры кишечника. Необходимо придерживаться здорового образа жизни и укреплять иммунитет. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Людям, склонным к развитию аллергии, нужно иметь под рукой антигистаминные препараты, которые помогут облегчить состояние до визита к врачу. Стоит обсудить их применение с доктором заранее, так как некоторые лекарства противопоказаны детям, беременным женщинам, при управлении автомобилем.</span></p>",
"clinical_picture": "<p>Местные проявления крапивницы (появление сыпи на любом участке кожи):</p>\r\n<ul class=\"list list-description\">\r\n<li><a title=\"Перейти на страницу симптома Покраснение кожи\" href=\"/symptom/pokrasnenie_kozhi/\">покраснение</a> участков кожи;</li>\r\n<li>появление волдырей — ограниченного отека кожи различного размера и формы, возвышающегося над поверхностью кожи;</li>\r\n<li><a title=\"Перейти на страницу симптома Зуд\" href=\"/symptom/zud/\">зуд</a> или жжение в местах высыпаний;</li>\r\n<li>полное исчезновение элементов в период до 24 часов, обычно от нескольких минут до часа.</li>\r\n</ul>",
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"parent": null,
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"standards": [
5161
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},
{
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},
"code": "Q75.0",
"name": "Краниосиностоз",
"icd_name": "Краниосиностоз",
"gender": 0,
"age_min": 1,
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"lead": "преждевременное срастание у ребенка одного или нескольких швов, разделяющих черепные кости",
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"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Природа данного заболевания на сегодняшний день мало изучена. Но существует большое количество теорий возникновения краниостеноза. Теории говорят о таких причинах:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">гормональные</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">внутриутробные</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">наследственные нарушения</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">сдавление головы плода в матке и пр.</span></p>\r\n</li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Одним из факторов патогенеза официально признан медициной дефект в гене рецептора фактора роста фибробластов. Основные швы свода черепа:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">коронарный</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">сагиттальный</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">метопический</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">лямбдовидный</span></p>\r\n</li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если костный шов поражен, фиксируют компенсаторный рост костей перпендикулярно его оси. В результате этого процесса возникает характерная деформация – своя для каждого из замкнутых швов.</span></p>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При обращении родителей ребенка с жалобами на диспропорциональный череп, беспокойство, тошноту, рвоту, врач проводит осмотр, при котором проводится краниометрия – измерение антропометрических показаний головы с помощью сантиметровой ленты. Обращает на себя внимание нарушение темпов роста черепа. Затем для уточнения состояния пациента требуется консультация невропатолога, офтальмолога, генетика. Параллельно с этим назначаются инструментальные исследования:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #141412; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгенография черепа (краниография) является основным методом диагностики. При краниосиностозе выявляется деформация черепа, отсутствие одного или нескольких швов, диспропорция толщины свода черепа, а также признаки внутричерепной гипертензии – пальцевидные вдавления, усиленный сосудистый рисунок.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #141412; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Осмотр глазного дна. При этом исследовании на глазном дне видны отек соска зрительного нерва и признаки венозного застоя.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #141412; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ультразвуковая функциональная венография. При краниосиностозе отмечается затруднение венозного оттока сосудов головного мозга и косвенные признаки внутричерепного повышенного давлении.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #141412; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Электрокардиография, эхокардиография и ультразвуковое исследование внутренних органов проводится с целью выявления сопутствующих аномалий развития, а также как подготовка перед операцией для выявления общего состояния организма ребенка.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #141412; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К современным методам исследования относится компьютерная томография, с помощью ее можно узнать об отсутствии какого-либо шва, наличии повышенного внутричерепного давления, различных компенсаторных изменений. Метод является очень точным и позволяет зарегистрировать минимальные отклонения.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #141412; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В сложных случаях краниосиностоза, при сочетанном поражении швов черепа показано выполнения ангиографии для выявления коллатеральных путей кровотока с целью уменьшения операционные риски.</span></p>\r\n</li>\r\n</ul>",
"treatment": "<p><span id=\"docs-internal-guid-54e7d665-7fff-5c5f-1473-68d104101a15\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Основное лечение краниосиностоза – хирургическая коррекция костной деформации черепа. Оптимальное время для проведения оперативного вмешательства – первые 6-9 месяцев жизни ребенка. Данные сроки обусловлены тем, что в этом периоде наблюдается наиболее интенсивное развитие тканей головного мозга, которому может препятствовать деформация черепной коробки. Кроме того, кости черепа в этом возрасте быстро восстанавливают свою структуру без развития осложнений. Объем и техника операции зависят от формы краниосиностоза и сопутствующих патологий. В 2-3-х летнем возрасте коррекция проводится исключительно с целью ликвидировать косметический дефект. Помимо хирургического лечения осуществляется изменение рациона ребенка в соответствии с возрастными требованиями. При развитии интеркуррентных заболеваний показана медикаментозная терапия.</span></span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Специфической профилактики для данной патологии не существует. Неспецифические меры подразумевают медико-генетическую консультацию семьи и планирование беременности, охрану здоровья женщины при вынашивании ребенка, рациональное питание, отказ от вредных привычек и исключение всех потенциальных этиологических факторов развития краниосиностоза.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основным признаком краниосиностоза является деформированный череп, при этом голова принимает неестественную форму, отмечается ее чрезмерный рост в сторону, противоположную от места стеноза.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Затем в костную деформацию начинает вовлекаться и лицевая часть черепа, особенно страдает область глаз.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">У детей проявляются признаки внутричерепной гипертензии. В младенческом возрасте она определяется по вынужденному положению головы, беспричинному крику ребенка, тошноте и рвоте.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При преждевременном закрытии нескольких черепных швов возникает гидроцефалия - нарушение оттока цереброспинальной жидкости из желудочков головного мозга. Признаками гидроцефалии является несоответствующий возрасту рост головы, напряженный выбухающий родничок, косоглазие.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если в процесс вовлекается венечный шов, происходит деформация черепа в фронтально-орбитальной зоне, что приводит к быстро прогрессирующему ухудшению зрения.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При синдромных вариантах краниосиностоза из-за недоразвития верхней челюсти у детей часто отмечается нарушение дыхания, особенно ночью, а также задержка речевого развития.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Чем длительнее течет краниосиностоз, тем сильнее страдает функции коры головного мозга. Вначале дети не отстают в психомоторном развитии, но с течением времени начинают проявляться симптомы задержки, вплоть до утраты уже приобретенных навыков (зависит от варианта заболевания).</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Краниосиностоз может отмечаться и в детском возрасте 8 – 10 лет, тогда симптомы не так выражены, развивается компенсированная форма болезни, нуждающаяся в грамотной диагностике.</span></p>",
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