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"lead": "Область медицины, включающая в себя лечение 515 заболеваний. В 980 клиниках России оказывается помощь по этому направлению медицины.",
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"lead": "Область медицины, включающая в себя лечение 102 заболеваний. В 16 клиниках России оказывается помощь по этому направлению медицины.",
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"lead": "Область медицины, включающая в себя лечение 173 заболеваний. В 95 клиниках России оказывается помощь по этому направлению медицины.",
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"lead": "Область медицины, включающая в себя лечение 335 заболеваний. В 180 клиниках России оказывается помощь по этому направлению медицины.",
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"lead": "Область медицины, включающая в себя лечение 136 заболеваний. В 177 клиниках России оказывается помощь по этому направлению медицины.",
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"lead": "Область медицины, включающая в себя лечение 351 заболевания. В 523 клиниках России оказывается помощь по этому направлению медицины.",
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"lead": "Область медицины, включающая в себя лечение 908 заболеваний. В 1399 клиниках России оказывается помощь по этому направлению медицины.",
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"lead": "Область медицины, включающая в себя лечение 984 заболеваний. В 69 клиниках России оказывается помощь по этому направлению медицины.",
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"code": "M51",
"name": "Поражение межпозвоночных дисков других отделов",
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"lead": "Нарушение здоровья, относящееся к группе другие дорсопатии",
"description": "Грыжа межпозвонкового диска поясничного отдела позвоночника — выпячивание или выпадение фрагментов межпозвонкового диска поясничного отдела в позвоночный канал, возникающее в результате остеохондроза позвоночника, травмы и приводящее к сдавлению нервных структур. Грыжи дисков пояснично - крестцового отдела позвоночника — довольно распространенное явление (300 на 100 000 населения). \r\nЧаще встречается у мужчин 30–50 лет. ",
"etiology": "<p>Причинами появления грыжи в поясничном отделе чаще всего являются:</p>\r\n<ul>\r\n<li>остеохондроз;</li>\r\n<li>большие физические нагрузки, подъём тяжестей;</li>\r\n<li>резкие наклоны, повороты, падения;</li>\r\n<li>сколиози другие искривления позвоночника;</li>\r\n<li>дисплазия тазобедренного сустава;</li>\r\n<li>нарушение обмена веществ;</li>\r\n<li>травмы позвоночника, особенно после автомобильных аварий.</li>\r\n</ul>\r\n<p> </p>\r\n<p>Факторами риска для появления поясничной грыжи являются:</p>\r\n<ul>\r\n<li>лишний вес, неправильное питание;</li>\r\n<li>работа за компьютером, постоянное вождение автомобиля;</li>\r\n<li>недостаточная физическая нагрузка;</li>\r\n<li>наследственная предрасположенность;</li>\r\n<li>старение организма;</li>\r\n<li>инфекции, переохлаждение;</li>\r\n<li>курение.</li>\r\n</ul>\r\n<p> </p>",
"pathogenesis": "<p>Поясничный отдел позвоночника состоит из 5 позвонков. Они соединены между собой межпозвоночными дисками. Диски обеспечивают амортизацию позвонков, равномерно распределяют нагрузку на поясничный отдел. Каждый диск состоит из твёрдой оболочки — фиброзного кольца, внутри которого находится полужидкое ядро.</p>\r\n<p>Пульпозное ядро не сразу оказывается за пределами диска. До этого проходит несколько стадий:</p>\r\n<p>Протрузия диска. Фиброзное кольцо слегка теряет упругость, в результате пульпозное ядро смещается в одну из сторон. Если на этом этапе обеспечить правильное чередование отдыха и лечебных упражнений, процесс межпозвоночного грыжеобразования можно остановить. Неполное выпадение участка диска. Фиброзное кольцо разрушается в одном участке, и туда устремляется материал пульпозного ядра. Полный пролапс диска. Ядро выходит за пределы фиброзного кольца, сдавливая тела позвонков и структуры нервной системы. Секвестрация диска. Так называется состояние, когда участок «обретшего свободу» пульпозного ядра попадает в спинномозговой канал. Это приводит к защемлению нервных окончаний, вплоть до сдавливания спинного мозга. Без своевременного лечения болезнь может вызвать паралич ног.</p>",
"diagnostics": "<p>Диагностика грыжи на начальных этапах включает в себя неврологический осмотр, где врач-невролог проводит следующие исследования:</p>\r\n<p>определения рефлексов с сухожилий, расположенных на ногах; теста с подъемом прямой ноги; исследования температурной, болевой и вибрационной чувствительности по всей поверхности ног, в области ягодиц, промежности, нижней половины живота.</p>\r\n<p>При межпозвоночной грыже пояснично-крестцового отдела будут отмечаться чувствительные расстройства в зоне, иннервируемой пораженным корешком, невролог определит выпадение или снижение сухожильных рефлексов, выявит глубокие нарушения биомеханики движений пораженными конечностями. Неврологический осмотр помогает предварительно определить пораженный сегмент.</p>\r\n<p>Сам же диагноз ставится на основании одной из томографий – магнитно-резонансной или компьютерной мультиспиральной – пояснично-крестцового отдела. При указании на повреждение спинного мозга диагностика может дополниться контрастной миелографией – исследованием, при котором путем люмбальной пункции в спинномозговой канал будет введено контрастное для рентгена вещество. Далее выполняется рентген, на котором видно, как контрастное вещество проходит в позвоночном канале, не накапливается ли на каком-то уровне (последнее означает, что сдавлен спинной мозг).</p>\r\n<p>Электромиография позволяет дифференцировать сдавление корешка от периферической невропатии.</p>",
"treatment": "<p>Основной метод — консервативная терапия</p>\r\n<p>Консервативная терапия включает:</p>\r\n<ul>\r\n<li>Тракционное лечение (вытяжение поясничного отдела позвоночника)</li>\r\n<li>Эпидуральные блокады смесью растворов местного анестетика и глюкокортикостероида</li>\r\n<li>НПВС, анальгетики, сосудистые препараты, витаминотерапия</li>\r\n<li>Массаж, физиотерапия, акупунктура</li>\r\n<li>После купирования острой фазы — ЛФК для повышения мышечной силы.</li>\r\n</ul>\r\n<p>Оперативное лечение</p>\r\n<ul>\r\n<li>Показаниями к проведению операции является неэффективность адекватного консервативного лечения при наличии признаков стабильной компрессии корешка (особенно при появлении мышечной слабости) Неотложное хирургическое вмешательство проводится при сдавлении корешков конского хвоста.</li>\r\n</ul>\r\n<p>Суть операции – в высвобождении спинного мозга или корешков от сдавливающей их грыжи. Выполняться это может следующим образом:</p>\r\n<p>Эндоскопическим способом. В области позвоночника делается 3 микроразреза, в один вводится камера, которая будет транслировать изображение на монитор, через 2 других хирурги работают микроинструментарием. Удаляется грыжевое выпячивание и остаточные элементы пульпозного ядра. Чрескожная дискэктомия. Это вмешательство предполагает удаление через прокол в межпозвоночном диске его разрушенного ядра. Далее производят его замену особым веществом, которое, для приобретения нужных свойств, должно охладиться. Эндопротезирование диска. Поврежденный диск удаляется, на его месте ставится имплант. Лазерная реконструкция. Пульпозное ядро наиболее насыщено водой. На это и рассчитан лазер, который обладает свойством выпаривать влагосодержащие структуры.</p>",
"prevention": "<p>Для профилактики поясничной грыжи рекомендуется:</p>\r\n<ul>\r\n<li>больше ходить пешком, заниматься спортом — плаванием, йогой;</li>\r\n<li>следить за осанкой, при ходьбе держать голову и спину прямо;</li>\r\n<li>при работе за компьютером опираться на спинку стула;</li>\r\n<li>при долгом сидении делать перерывы и выполнять упражнения — например, 10 наклонов туловищем в разные стороны. При этом нужно держать руки на пояснице;</li>\r\n<li>перед тем, как поднять тяжесть, сгибать колени, держать спину прямо;</li>\r\n<li>распределять вес в обе руки;</li>\r\n<li>спать на ортопедическом матрасе;</li>\r\n<li>употреблять курятину, говядину, рыбу, молочные продукты;</li>\r\n<li>отказаться от жареных блюд, консервированных продуктов, острых приправ;</li>\r\n<li>не курить.</li>\r\n</ul>\r\n<p> </p>",
"clinical_picture": "<p>Различают следующие симптомы поясничной грыжи:</p>\r\n<ul>\r\n<li>Боль в пояснице – непостоянная, тупого, ноющего характера, постепенно нарастает, усиливается при движении, поворотах и наклонах, мышечном напряжении, подъёме тяжестей, кашле и чихании. Характерны повторные обострения на протяжении нескольких лет, может отдавать в ягодицу, ногу и далее по ноге до стопы («лампасные» боли)</li>\r\n<li>Прострелы — острая боль в пояснице, возникает внезапно, затем проходит (более половины больных связывают появление этой боли с конкретной травмой — падением, резким наклоном или поворотом туловища, подъёмом тяжести);</li>\r\n<li>Онемение, жжение, покалывание в ногах, «мурашки»;</li>\r\n<li>Изменение осанки с целью уменьшения боли – сколиоз;</li>\r\n<li>Симптом Ласега — появление боли в пояснице и в участке кожи, который иннервируется поражённым корешком (возможно также чувство онемения, ползания мурашек) при поднятии выпрямленной ноги у лежащего на спине пациента. Боль исчезает (или ослабевает) при сгибании ноги в коленном суставе и усиливается при тыльном сгибании стопы;</li>\r\n<li>Синдром каудогенной перемежающейся хромоты — боль в ногах при ходьбе (вследствие преходящего сдавления конского хвоста), вынуждающая больного останавливаться</li>\r\n<li>Вегетативные проявления: потливость, мраморность кожи</li>\r\n<li>В запущенных случаях — нарушение работы мочевого пузыря и кишечника, атрофия мышц ног, паралич.</li>\r\n</ul>\r\n<p> </p>",
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"name": "Рак мочеточника",
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"lead": "Рак мочеточника чаще всего представлен переходно-клеточной карциномой, в некоторых случаях – плоскоклеточным раком",
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"etiology": "<p>Рак мочеточника составляет в среднем 4% от всех опухолей верхних мочевых путей. Переходно-клеточный рак мочеточника составляет приблизительно 7% всех почечных опухолей. Факторы риска те же, что и для рака мочевого пузыря. Самый распространенный – это курение. Также доказано увеличение риска заболевания при злоупотреблении обезболивающими лекарственными препаратами (например, фенацетин), хроническом раздражении слизистой оболочки (при мочекаменной болезни, шистосомозе), при длительном контакте химическими веществами, используемыми в промышленности. Кроме того, жители Балкан с эндемической семейной нефропатией имеют необъяснимую предрасположенность развития рака мочеточников.</p>",
"pathogenesis": "<p>По мнению большинства патоморфологов, все папиллярные опухоли лоханки и мочеточника, являются разными стадиями единого процесса. Опухоли мочеточника бывают эпителиального (папиллома, сосочковый и плоскоклеточный рак) и соединительнотканного (фиброма, лейомиома, саркома) происхождения. Чаще наблюдаются эпителиальные опухоли. Первичные новообразования склонны к раннему метастазированию. Метастазы распространяются гематогенным и лимфогенным путем.</p>",
"diagnostics": "<p>Во время исследования крови и мочи обнаруживают такие же изменения, и при опухолях почечной лоханки.</p>\r\n<p>При цистоскопии в момент гематурии удается уточнить источник кровотечения. Кроме того, в случае локализации папиллярного новообразования в нижнем отрезке мочеточника, при цистоскопи, иногда можно наблюдать, как в момент сокращения его отверстия, ворсинки опухоли появляются в просвете мочевого пузыря. Расположение папиллярных опухолей вокруг отверстия одного из мочеточников может свидетельствовать о первичной опухоли в мочеточнике или почечной лоханке.</p>\r\n<p>Катетеризация мочеточника позволяет выявить характерный признак его опухоли - выделение крови из мочеточникового катетера в момент чистой мочи после проведения его выше (симптом Шевассю).</p>\r\n<p>С помощью экскреторной урографии определяют нарушения секреторной и экскреторной функции почек, проявляют уретерогидронефроз на стороне поражения и дефект наполнения мочеточника. На уретеропиелограмме по обе стороны от дефекта наполнения мочеточника определяют затёки рентгенконтрастного вещества (симптом жала змеи).</p>\r\n<p>Если диагноз сомнителен, выполняют уретероскопию, которая позволяет осмотреть мочеточник, установить размеры поражения и характер распространения опухоли, инфильтрацию стенки, изменения мочевых путей выше опухоли. Выполнение биопсии опухолевой ткани с последующим гистологическим ее исследованием, помогает определить до операции правильный диагноз и даже установить стадию заболевания.</p>",
"treatment": "<p>Радикальным методом лечения может быть только оперативное вмешательство. При тотальном поражении мочеточника опухолью показана нефроуретерэктомия с резекцией мочевого пузыря, при условии хорошо функционирующей противоположной почки. При низком расположении допустимы резекция мочеточника вместе с прилегающей к устью стенкой мочевого пузыря и уретероцистоанастомоз (прямой или по Боари). Помимо хирургического лечения применяют химио- и радиотерапию, однако чувствительность опухолевых клеток к ним мала.</p>\r\n<p>После проведённого лечения пациентам рекомендуют выполнение контрольных цистоскопий через определённые промежутки времени, т.к. рак мочеточника имеет тенденцию распространяться в мочевой пузырь. В случае выявления такого процесса в ранней стадии может потребоваться выполнение трансуретральной резекции мочевого пузыря или внутрипузырных инстилляций противоопухолевых препаратов. Контрольное обследование, направленное на выявление метастазов такое же, как для рака мочевого пузыря.</p>",
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"clinical_picture": "<p>Большинство пациентов обращаются за медицинской помощью при появлении гематурии – примеси крови в моче. Болезненность и учащение мочеиспускания могут присоединяться в тех случаях, когда мочевой пузырь также вовлечен в опухолевый процесс. При обтурации просвета мочеточника может возникнуть приступ почечной колики из-за нарушения оттока мочи от почки. В некоторых случаях может развиться гидронефроз – расширение полостной системы почки.</p>\r\n<p>Обследование обычно включает УЗИ или КТ с контрастированием. Диагноз должен быть подтвержден цитологически или гистологически. Уретероскопия, нефроскопия или обе диагностические процедуры выполняются для уточнения уровня и характера поражения мочеточника, а также для выполнения биопсии с целью определения гистологической структуры опухоли и стадии процесса. Кроме того для определения распространенности опухоли и наличия метастазов выполняют КТ органов брюшной полости и малого таза и рентгенографию грудной клетки.</p>",
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