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"lead": "Заболевание, характеризующееся первичным избирательным поражением миокарда",
"description": "<p>Кардиомиопатия - это <span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">заболевание миокарда неизвестной этиологии, основными признаками которой являются кардиомегалия (увеличение размеров сердца) и/или сердечная недостаточность.</span></p>\r\n<p><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\"> </span></p>",
"etiology": "<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Существует три группы основных причин развития первичной кардиомиопатии: врожденная, смешанная, и приобретенная. К вторичным относятся кардиомиопатии вследствие какого-либо заболевания.</span></p>\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Врождённая патология сердца развивается вследствие нарушения закладки тканей миокарда во время эмбриогенеза. Причин очень много, начиная от вредных привычек будущей матери и заканчивая стрессами и неправильным питанием. Также известны кардиомиопатии беременных и воспалительные кардиомиопатии, которые по существу можно назвать миокардитом.</span></p>\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К вторичным формам относятся следующие виды:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кардиомиопатия накопленная или инфильтративная. Для нее характерно накопление между клетками или в клетках патологических включений.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Токсическая кардиомиопатия.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эндокринная кардиомиопатия (метаболическая кардиомиопатия, дисметаболическая кардиомиопатия) возникает вследствие нарушения обмена веществ в сердечной мышце.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Алиментарная кардиомиопатия образуется в результате нарушения питания, а в частности при длительных диетах с ограничением мясных продуктов или голодании.</span></p>\r\n</li>\r\n</ul>",
"pathogenesis": "<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В основе ишемической кардиомиопатии лежит нарушение кровоснабжения миокарда, которое запускает цепочку патологических реакций: некроза, фиброза, активации тканевой ренин-ангиотензиновой системы. Важную роль играет механизм прекондиционирования, который заключается в многократных эпизодах ишемии с реперфузией сердечной мышцы. Частое повторение такого процесса активирует АТФ-зависимые насосы и увеличивает порог ишемического повреждения.</span></p>\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Морфологически при кардиомиопатии на фоне ИБС наблюдается увеличение массы сердца до 500-700 г и тотальное расширение его полостей. При этом наблюдается диспропорциональное истончение стенки левого желудочка, очаги крупноочагового фиброза сердечной мышцы. Характерно обширное атеросклеротическое поражение коронарных сосудов, участки артериальных стенозов и окклюзии, кальцификация в начальных отделах аорты.</span></p>",
"diagnostics": "<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Обследование начинается с подробного опроса пациента – сбора анамнестических данных. Это необходимо для установления первопричины патологии. Далее следует тщательная аускультация (выслушивание) сердечных тонов и шумов, после чего больного направляют на проведение инструментальных и лабораторных исследований. Основными из них являются:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Клинический и биохимический анализы крови, мочи. С их помощью оценивается функциональное состояние сосудов, печени, почек. Также помогает выявить первопричину болезни генетическая диагностика.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">ЭКГ. Регистрируется электрическая активность миокарда в момент исследования, отображаясь на кардиограмме характерными признаками КМП.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Холтеровское мониторирование ЭКГ. Оценивается степень нарушений ритма.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Рентгенография грудной клетки. Подтверждает увеличение сердца в размерах.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Эхокардиография (УЗИ сердца). Метод позволяет узнать точные размеры сердечных камер, их функциональную активность.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Коронарография. Показана при постоянных приступах стенокардии.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.2; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">МРТ. Проводится перед оперативным вмешательством.</span></p>\r\n</li>\r\n</ul>",
"treatment": "<p align=\"justify\">Специфическая терапия кардиомиопатий отсутствует, поэтому все лечебные мероприятия имеют целью предотвращение несовместимых с жизнью осложнений. Лечение кардиомиопатий в стабильной фазе амбулаторное, при участии кардиолога; периодическая плановая госпитализация в отделение кардиологии показана пациентам с тяжелой сердечной недостаточностью, экстренная – в случаях развития некупируемых пароксизмов тахикардии, желудочковой экстрасистолии, мерцательной аритмии, тромбоэмболий, отека легких.</p>\r\n<p align=\"justify\">Пациентам с кардиомиопатиями необходимо снижение физической активности, соблюдение диеты с ограниченным потреблением животных жиров и соли, исключение вредных окружающих факторов и привычек. Эти мероприятия существенно снижают нагрузку на сердечную мышцу и замедляют прогрессирование сердечной недостаточности.</p>\r\n<p align=\"justify\">При кардиомиопатиях целесообразно назначение диуретиков для уменьшения легочного и системного венозного застоя. При нарушениях сократимости и насосной функции миокарда применяются сердечные гликозиды. Для коррекции сердечного ритма показано назначение противоаритмических препаратов. Предотвратить тромбоэмболические осложнения позволяет использование антикоагулянтов и антиагрегантов в лечении пациентов с кардиомиопатиями.</p>\r\n<p align=\"justify\">В исключительно тяжелых случаях проводят хирургическое лечение кардиомиопатий: септальную миотомию (резекцию гипертрофированного участка межжелудочковой перегородки) с протезированием митрального клапана либо трансплантацию сердца.</p>\r\n<p>Летальность при ГКМП зависит от формы заболевания и возраста пациента. Прогноз хуже у молодых больных в отсутствие оперативного лечения. Смертность достигает 50 % в год от желудочковых нарушений ритма. Прогноз благоприятный у пациентов успешно перенесших оперативное вмешательство. Второй механизм смерти — застойная сердечная недостаточность, как правило у пациентов средней и старшей возрастной категории.</p>",
"prevention": "<p>Первичная профилактика направлена на предупреждение развития кардиомиопатии. С этой целью рекомендуется соблюдать следующие рекомендации, позволяющие снизить воздействие факторов риска возникновения этого патологического состояния:</p>\r\n<ul>\r\n<li>отказ от употребления высоких доз алкоголя;</li>\r\n<li>ограничение контакта с профессиональными вредностями, токсическими материалами;</li>\r\n<li>использование средств индивидуальной защиты на производстве;</li>\r\n<li>сбалансированное питание с достаточным содержанием белка, витаминов группы В, селена, карнитина;</li>\r\n<li>предупреждение развития метаболических расстройств, например, сахарного диабета;</li>\r\n<li>предупреждение и своевременное лечение вирусных инфекций;</li>\r\n<li>адекватное лечение воспалительных заболеваний сердечной стенки;</li>\r\n<li>планирование и профессиональное ведение беременности.</li>\r\n</ul>\r\n<p>К сожалению, встречаются идиопатические формы кардиомиопатиии, причина развития которых не установлена. Не существует методов профилактики возникновения и наследственной кардиомиопатии. Остается лишь добавить, что лицам с генетической предрасположенностью к данной патологии следует особенно тщательно соблюдать рекомендации по первичной профилактике. Родственники больных кардиомиопатией должны наблюдаться у кардиолога и регулярно выполнять УЗИ сердца.</p>\r\n<p>Вторичная профилактика</p>\r\n<p>Мероприятия вторичной профилактики кардиомиопатии направлены на предупреждение прогрессирования данного заболевания, а также препятствуют возникновению осложнений. Кроме того пациентам с таким диагнозом следует снизить риск развития заболевания, которые могут значительно ухудшить течение кардиомиопатии. Прежде всего, это профилактика ишемической болезни сердца и артериальной гипертензии.</p>\r\n<p>К методам вторичной профилактики кардиомиопатии относят следующее:</p>\r\n<ul>\r\n<li>отказ от занятий спортом и тяжелым физическим трудом. Таким пациентам показана регулярная легкая физическая нагрузка;</li>\r\n<li>регулярное наблюдение у специалиста;</li>\r\n<li>регулярное выполнение ЭхоКГ;</li>\r\n<li>проведение регулярной антибиотикопрофилактики инфекционного эндокардита дает возможность значительно снизить риск развития этого опасного состояния;</li>\r\n<li>регулярный прием препаратов, назначенных специалистом. Обычно терапия таких больных включает использование диуретиков, антикоагулянтов, антигипертензивных средств и антиаритмиков;</li>\r\n<li>хирургическое лечение некоторых разновидностей кардиомиопатии является эффективным методом улучшения качества жизни пациентов с таким диагнозом. Так протезирование митрального клапана, удаление сосочковых мышц и части межжелудочковой перегородки при гипертрофической кардиомиопатиии дает возможность на долгие годы нормализовать внутрисердечную гемодинамику;</li>\r\n<li>полный отказ от курения и приема алкоголя;</li>\r\n<li>установка электрокардиостимулятора может быть показана некоторым больным с кардиомиопатией с целью предупреждения развития жизнеугрожающих аритмий;</li>\r\n<li>борьба с избыточной массой тела;</li>\r\n<li>снижение потребления соли;</li>\r\n<li>избегание стрессовых ситуаций;</li>\r\n<li>нормализация режима труда и отдыха;</li>\r\n<li>регулярный контроль уровня холестерина и сахара крови;</li>\r\n<li>отказ от самолечения.</li>\r\n</ul>\r\n<p>Проведение грамотной первичной и вторичной профилактики кардиомиопатии дает возможность предупредить развитие и прогрессирование этого заболевания.</p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Долгое время болезнь протекает бессимптомно, проявляя себя только изредка недомоганием и дискомфортом за грудиной. Человек может узнать о своем заболевании случайно – во время прохождения в целях профилактики электрокардиографии или ультразвукового исследования сердца.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При значительном изменении сердечного аппарата больной жалуется на следующие патологические признаки:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #092148; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; 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font-size: 6.999999999999999pt; font-family: Verdana; color: #092148; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">отечность голеней, лодыжек, стоп;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #092148; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">головные боли с эпизодами головокружения;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #092148; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">давящие боли в области сердца, сопровождающиеся онемением левой половины туловища;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; 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},
"code": "I42.6",
"name": "Алкогольная кардиомиопатия",
"icd_name": "Алкогольная кардиомиопатия",
"gender": 0,
"age_min": 40,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "i42.6_alkogolnaya_kardiomiopatiya",
"lead": "заболевание, проявляющееся в виде диффузного поражения сердечной мышцы, обусловленное длительным употреблением алкоголя",
"description": "",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Первейшая причина рассматриваемого заболевания – систематическая интоксикация организма спиртосодержащими напитками. В качестве причин второго плана можно указать:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">ослабленная иммунная система;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">поражение инфекциями или вирусными бактериями;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">отсутствие в рационе нужно количества витаминов и белков;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">врожденный порок сердца;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">наследственная предрасположенность к кардиомиопатии;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нарушенный режим работы и отдыха;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">постоянные стрессовые ситуации.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Риск развития алкогольной кардиомиопатии прямо пропорционален длительности приема и объему употребляемого этанола. Считается, что для развития смертельной формы кардиомиопатии требуется ежедневно в течение 3-10 лет принимать от 60 до 150 г чистого этанола в сутки.</span></p>",
"pathogenesis": "<p><span id=\"docs-internal-guid-3aeb7bb3-7fff-98fa-ca7f-f57ad6484b83\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Основной причиной зарождения и развития этой патологии является негативное воздействие токсических продуктов метаболизма этанола на миокард. В частности, на работу сердца негативно влияет ацетальдегид. Данное вещество образуется в результате расщепления этанола клетками печени. Ацетальдегид поступает в систему кровообращения и после достижения сердца вызывает в нем нарушения электролитного баланса и расстройства обмена веществ. Эти нарушения способствуют возникновению аритмии и снижению функциональной активности сердечной мышцы. </span></span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Перечень диагностических мероприятий включает:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Объективное обследование. Может обнаруживаться беспокойное или заторможенное поведение, синюшность кончиков пальцев, носа, ушей, верхней части грудной клетки. При пальпации отмечается повышенная потливость, отеки и похолодание конечностей, набухание и пульсация сосудов шеи. Увеличение размеров сердца при перкуссии свидетельствует о гипертрофии или дилатации его камер. Аускультативно определяются патологические шумы, характерные для структурных изменений миокарда, клапанов.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Электрокардиография. Является базовым инструментальным методом исследования, позволяет выявить нарушения ритма, получить данные об органическом поражении миокарда, предположить его токсическую этиологию. ЭКГ может дополняться суточным мониторированием по Холтеру. При отсутствии противопоказаний назначают велоэргометрию.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эхокардиография. ЭхоКГ применяется для оценки состояния коронарных артерий и клапанного аппарата, обнаружения гипертрофии и дилатации миокарда, снижения скорости кровотока, определения давления в камерах. Выполняется для дифференциальной диагностики кардиомиопатии и перикардитов.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгенография ОГК. На рентгенограммах грудной клетки визуализируются признаки увеличения камер сердца, реже дилатация восходящей аорты. Методика используется для уточнения состояния других крупных сосудов, выявления патологических образований. На основании снимков можно заподозрить пороки клапанов.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Комплексная терапия заболевания включает прекращение употребления этанолсодержащих напитков, борьбу с сердечной недостаточностью, коррекцию расстройств метаболизма, восстановление функций других органов. Положительный эффект от курсового лечения возможен на ранней стадии болезни при отсутствии необратимых нарушений. На поздних этапах необходим непрерывный прием лекарственных препаратов. Выделяют следующие направления лечения кардиомиопатии:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Изменение образа жизни. Предусматривает полный отказ от алкоголя, исключение курения. Назначается диета с большим количеством белка, ограничением соли и жиров. Предпочтение отдается приготовленным на пару, тушеным или отварным блюдам, питание осуществляется небольшими порциями 4-6 раз в день. Суточное потребление жидкости составляет не более 1,5 литров. Важны достаточные физические нагрузки, здоровый сон, снижение уровня стресса.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Медикаментозная терапия. Является основой лечения заболевания, предусматривает использование нескольких групп препаратов, которые назначаются индивидуально с учетом симптоматики. Для нормализации артериального давления применяются антигипертензивные средства, для предотвращения нарушений ритма — антиаритмики, для устранения отеков – мочегонные, для снижения уровня холестерина крови — статины. При тяжелом течении план лечения дополняют сердечными гликозидами для купирования приступов тахиаритмий, антиагрегантами и антикоагулянтами для предотвращения тромбоэмболических осложнений.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хирургическое вмешательство. При неэффективности консервативной терапии, быстром прогрессировании алкогольной кардиомиопатии с высоким риском развития опасных осложнений рассматривается вопрос о трансплантации сердца. Метод обеспечивает высокую 10-летнюю выживаемость (порядка 75%), применяется при удовлетворительном состоянии организма, отсутствии грубых психических и интеллектуальных нарушений. </span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактические методы включают в себя отказ от злоупотребления алкогольными напитками. Не последнюю роль играет соблюдение полноценного питания, поскольку сердечная мышца должна снабжаться не только необходимыми микроэлементами и витаминами, но и белком.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Первичными признаками алкогольной кардиомиопатии принято считать сбои сердечного ритма и сна, появление головных болей. В дальнейшем даже при незначительной нагрузке возникает одышка. Нередко проявляются застойные явления в виде отеков. Чаще всего больные не видят взаимосвязи между симптомами и своей пагубной привычкой, а то и вовсе отрицают ее наличие. Их характерными внешними признаками выступают:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">постоянное покраснение лица;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">тремор рук;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">возбужденность и разговорчивость, не вызванные объективными обстоятельствами;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">резкое изменение массы тела – как в сторону увеличения, так и уменьшения;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">весьма характерен сине-багровый нос, на котором отчетливо видны расширенные сосуды;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">глаза в целом отдают краснотой, а склера в частности – желтизной.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Характерными симптомами этого заболевания являются бессонница, сердечные боли, нехватка воздуха, ускоренное сердцебиение, похолодание конечностей, чувство жара, повышенная потливость. Медицинское обследование выявляет аритмию, тахикардию, увеличенное давление, сбои в функционировании печени и почек.</span></p>",
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