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"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дивертикулярная болезнь - это хроническое заболевание, которое возникает из-за образования в стенке кишечника мешкообразного выпячивания (дивертикула), и, как следствие, застойного процесса и развития воспаления.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Наиболее значимый фактор развития дивертикулярной болезни толстого кишечника – диета, бедная растительной клетчаткой. В этой связи отмечается повышенная заболеваемость дивертикулезом в развитых странах, где большинство населения употребляет богатую клетчаткой пищу в значительно меньших количествах.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Клетчатка входит в состав овощей, фруктов и злаков. Она способствует размягчению стула и более легкому транзиту химуса по кишечнику. При недостатке клетчатки в пищевом рационе развивается склонность к затруднениям опорожнения кишечника, запорам. Частые запоры способствуют повышению давления в кишечнике. В местах, где имеется ослабление кишечной стенки в результате повышения внутрикишечного давления, возникают выпячивания. Со временем, формируются постоянные выпячивания кишечной стенки, которые могут стать очагом размножения бактериальной флоры.</span></p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Когда в рационе мало растительной клетчатки, в кишечнике нарушается пассаж каловых масс и возникают запоры. Давление в просвете кишки повышается и выдавливает слабые участки стенки наружу в виде дивертикулов.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">У образовавшихся дивертикулов нет мышечного слоя, они не могут сокращаться. Поэтому попавшие каловые массы и остатки пищи задерживаются внутри дивертикула.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Со временем каловые массы твердеют и превращаются в каловый камень — копролит, или фекалит. Этот камень давит на стенку дивертикула, тем самым нарушая её кровоснабжение. В итоге развивается воспаление — острый дивертикулит.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Развитие воспаления иногда связано с особенностями кишечной флоры. Нередко у пациентов с дивертикулярной болезнью наблюдается рост протеолитических бактерий.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При продолжающемся воспалении в стенке дивертикула возникает микроперфорация. Через это отверстие бактерии распространяются и поражают ткани, окружающие кишку — развивается так называемый острый околокишечный инфильтрат. При этом другие органы (тонкая кишка, придатки матки, мочевой пузырь) фактически \"приклеиваются\" к инфильтрату, образуя плотную трудноразделимую массу.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При серьёзном повреждении стенки дивертикула развивается макроперфорация. Она способствует образованию более тяжёлых осложнений — абсцесса и перитонита.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кишечное кровотечение при дивертикулёзе вызывают скопившиеся каловые камни. Копролиты сдавливают стенку дивертикула, запуская процесс её разрушения и повреждая мелкие сосуды, расположенные рядом.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Обследование пациента с подозрением на дивертикулярную болезнь толстого кишечника осуществляется врачом-проктологом, начинается со сбора жалоб, анамнеза и физикального осмотра. При этом, как правило, выявляются особенности диеты, склонность к запорам, при осмотре может отмечаться болезненность живота и его увеличение. Подтверждение диагноза производят с помощью инструментальных и лабораторных методов диагностики.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При исследовании крови могут отмечаться общие признаки инфекционного воспаления (лейкоцитоз, нейтрофилия, ускорение СОЭ). При имеющем место внутреннем кровотечении может отмечаться анемия. Признаки воспаления кишечника также могут отмечаться и в копрограмме. Лабораторное подтверждение имеющегося воспалительного процесса при дивертикулярной болезни толстого кишечника может говорить о развитии дивертикулита.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основным диагностическим методом выявления дивертикулов в толстом кишечнике является колоноскопия. Кроме того, при колоноскопии возможно выявить источник внутреннего кровотечения и исключить другие заболевания толстого кишечника. Ирригоскопия с контрастным веществом позволяет выявить выпячивания кишечной стенки.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При легком течении заболевания для облегчения клинических проявлений чаще всего достаточно соблюдения рекомендованной диеты, способствующей снижению давления в толстом кишечнике. Введение в рацион достаточного количества клетчатки обеспечивают облегчение прохождения кишечного содержимого по пищеварительному тракту. Однако, если мер по коррекции диеты недостаточно, необходимо назначение препаратов, способствующих устранению запоров (тримебутин) и обезболивающих спазмолитических средств при выраженной болезненности.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Развитие дивертикулита требует противовоспалительной и бактерицидной терапии. Для успешного лечения дивертикулита необходимо снятие нагрузки на толстый кишечник, чему способствуют меры по изменению рациона, а также назначается постельный режим. Своевременно назначенный курс антибиотикотерапии, как правило, подавляет развивающуюся инфекцию. Однако, в некоторых случаях консервативное лечение может быть безуспешным либо развитие осложнений требует немедленного хирургического вмешательства.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Абсолютными показаниями к операции являются: перфорация толстой кишки с выходом кишечного содержимого в брюшную полость, перитонит, прогрессирующий абсцесс, полная кишечная непроходимость, массивное кровотечение, высокая вероятность рака кишечника. Кроме того, показанием к оперативному вмешательству является неэффективность консервативного лечения, периодические небольшие внутренние кровотечения, выраженная анемия, свищи, частое рецидивирование дивертикулита. Как правило, производят резекцию пораженного участка кишечника с последующим восстановлением кишечника при помощи реконструктивной операции.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основные меры профилактики повторного появления дивертикулита:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">соблюдать высокошлаковую диету, которая должна включать не менее 25 г растительной клетчатки в день;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">контролировать качество и частоту дефекации;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">не допускать развитие запоров: пить 2-3 литра воды в день, есть продукты с растительной клетчаткой, принимать слабительные на растительной основе.</span></li>\r\n</ul>",
"clinical_picture": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Чаще всего дивертикулез длительное время протекает бессимптомно, однако у некоторых больных могут отмечаться периодические боли в животе по типу спазмов. Зачастую выявляется склонность к запорам и увеличение живота. При развитии дивертикулита возникает боль в животе, чаще всего в левой его части, болезненность при пальпации, тошнота, рвота, запор. Нередко повышается температура тела, отмечается озноб, слабость, головная боль (симптомы общей интоксикации). Тяжесть течения и выраженности клинических симптомов зависит от степени поражения кишечника и имеющихся осложнений.</span></p>",
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