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"code": "L04",
"name": "Острый лимфаденит",
"icd_name": "Острый лимфаденит",
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"slug": "l04_ostryy_limfadenit",
"lead": "острое гнойное воспаление лимфатических узлов.",
"description": "Лимфаденит – неспецифическое или специфическое воспалительное поражение лимфоузлов. Лимфаденит характеризуется местной болезненностью и увеличением лимфатических узлов, головной болью, недомоганием, слабостью, повышением температуры тела. \r\n\r\n",
"etiology": "<p>Возбудителями неспецифического лимфаденита обычно выступает гноеродная флора - стафилококки и стрептококки, а также выделяемые ими токсины и продукты тканевого распада, которые проникают в лимфоузлы лимфогенным, гематогенным или контактным путем. Первичным очагом при неспецифическом лимфадените могут являться гнойные раны, панариции, фурункулы, карбункулы, флегмоны, рожистое воспаление, трофические язвы, тромбофлебит, кариес, остеомиелит. Местные воспалительные процессы чаще сопровождаются регионарным лимфаденитом.</p>\r\n<p>Лимфаденит у детей часто бывает связан с воспалительными процессами ЛОР-органов (гриппом, отитом, хроническим тонзиллитом, ангиной), детскими инфекциями (скарлатиной, дифтерией, паротитом), а также кожными заболеваниями (пиодермией, экссудативным диатезом, инфицированной экземой и др.).</p>\r\n<p>Причиной специфического лимфаденита являются возбудители туберкулеза, сифилиса, гонореи, актиномикоза, чумы, сибирской язвы, туляремии и др. инфекций.</p>",
"pathogenesis": "<p>Инфекция поступает в регионарные лимфатические узлы с током лимфы, оттекающей из первичных гнойных очагов. Лимфаденит может возникнуть и без предшествующего лимфангита, причем первичный очаг бывает настолько ничтожен и так быстро заживает, что к моменту возникновения лимфаденита обнаружить место вхождения инфекции уже не всегда удается. В редких случаях возможно попадание инфекции в лимфатические узлы вместе с кровотоком. Лимфаденит иногда возникает и вследствие непосредственного перехода воспалительного процесса с тканей, окружающих узел.<br /> Лимфаденит следует рассматривать как проявление барьерной функции лимфатической системы, ограничивающей дальнейшее распространение инфекции и ее токсинов. Вместе с тем лимфаденит сам по себе может стать исходным пунктом для развития тяжелого гнойного процесса (аденофлегмона, сепсис).</p>",
"diagnostics": "<p>При постановке диагноза лимфаденит, врач проводит сбор анамнеза, и далее основывается на результатах пальпации тех областей, на которые жалуется пациент.</p>\r\n<p>Далее, обязательно назначается общий анализ периферической крови больного, в котором могут быть все признаки воспалительного процесса (в крови будет обнаружено при этом большое количество лейкоцитов, ускорение СОЭ, токсическая зернистость сегментоядерных нейтрофилов).</p>\r\n<p>Для уточнения и подтверждения диагноза лимфаденита назначается ультразвуковое исследование пораженных лимфатических узлов, пункция этих узлов. После пункции делают посев содержимого для того, чтобы определить сам микроорганизм и его чувствительность к препаратам антибактериального действия.</p>",
"treatment": "<p>Катаральный и гиперпластический острый лимфаденит лечится консервативно. Необходимо создание покоя для области поражения, проведение адекватной антибиотикотерапии на основании чувствительности микробной флоры, УВЧ-терапии, витаминотерапии. При гнойном лимфадените показано вскрытие сформировавшегося абсцесса, аденофлегмоны, дренирование и санация очага по принципам ведения гнойных ран. Назначается активная дезинтоксикационная и антибактериальная терапия.</p>",
"prevention": "<p>К профилактическим методам лимфаденита можно отнести здоровый образ жизни и максимальное избегание инфекционных заболеваний.</p>\r\n<p>Так же профилактическими методами лимфаденита являются методы по предупреждению травм различного характера, методы борьбы с раневой инфекцией, и рационализация лечения воспалительных гнойных заболеваний.</p>\r\n<p> </p>",
"clinical_picture": "<p>Острый лимфаденит может проявлять себя в виде общей и местной симптоматики.</p>\r\n<p>Общие симптомы воспаления:</p>\r\n<ul>\r\n<li>повышение температуры до высоких показателей (вплоть до 40°С);</li>\r\n<li>проявление озноба;</li>\r\n<li>сильная мигрень;</li>\r\n<li>общая сильно выраженная слабость;</li>\r\n<li>боль в мышцах;</li>\r\n<li>плохой сон.</li>\r\n</ul>\r\n<p>Местные проявления острого лимфаденита:</p>\r\n<ul>\r\n<li>увеличенные лимфоузлы;</li>\r\n<li>появление красного отека над лимфоузлами;</li>\r\n<li>возникновение заметной опухоли кожных покровов в области лимфоузлов;</li>\r\n<li>болезненные ощущения, как при прощупывании лимфоузлов, так и в состоянии покоя;</li>\r\n<li>повышение местной температуры кожных покровов;</li>\r\n<li>нарушение двигательной функции той области, где расположены лимфоузлы.</li>\r\n</ul>",
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"code": "L05",
"name": "Пилонидальная киста",
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"lead": "врождённая аномалия развития кожи крестцово-копчиковой области, связанная с неполной редукцией рудиментарной каудальной связки. ",
"description": "Для заболевания характерно наличие врождённых первичных свищевых втяжений в межягодичной складке. Нередко из таких втяжений выстоят волосы. ",
"etiology": "<p>Считают, что эпителиальный копчиковый ход является врожденным дефектом развития кожи, обусловленным неполной редукцией мышц и связок хвоста.</p>",
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"diagnostics": "<p>Местные изменения настолько типичны, что спутать копчиковый ход с другими поражениями этой области почти невозможно. При введении в один из свищей метиленового синего краска выходит из всех остальных ходов и вторичных свищей и не проходит в прямую кишку.</p>",
"treatment": "<p>Радикальное лечение пилонидальной кисты проводится только хирургическим путем, в условиях стационара хирургического или колопроктологического отделения. Существуют две тактики хирургического лечения:</p>\r\n<ol>\r\n<li>В острый период вскрывается и дренируется гнойник. После чего через 1–2 недели проводится радикальная операция – иссечение кисты в пределах здоровых тканей.</li>\r\n<li>В острый период сразу проводится радикальная операция – иссечение кисты единым блоком в пределах здоровых тканей (при этом необходимо сохранить целостность кисты, во избежание инфицирования операционной раны).</li>\r\n</ol>\r\n<p>Операция завершается ушиванием краев раны. Хотя, на усмотрение хирурга, рана может оставаться открытой и долго заживать вторичным натяжением; иногда до 6 месяцев (Прим. автора). При иссечении кисты копчика всегда имеется дефицит тканей, что приводит к чрезмерному натяжению краев раны и негативно сказывается на ее заживлении. Практически всегда послеоперационные раны заживают долго, причиняя значительные неудобства пациенту. При этом частота рецидива достигает 10–40%.</p>\r\n<p>Радикальная операция всегда проводится в условиях наркоза. В послеоперационном периоде пациенты в обязательном порядке получают антибактериальные препараты широкого спектра действия, а также противовоспалительные средства.</p>",
"prevention": "<p>Всем, кто перенес радикальное оперативное вмешательство по поводу эпителиального копчикового хода, желательно соблюдать следующие рекомендации: <br />- в течение трех недель после операции не разрешается сидеть, поднимать тяжести; после снятия швов целесообразно ежедневно принимать гигиенический душ с промыванием межъягодичной складки; <br />- в течение 6 месяцев после операции 2 раза в месяц необходимо производить эпиляцию в зоне операции.</p>",
"clinical_picture": "<p>Эпителиальный копчиковый ход расположен по средней линии в межъягодичной складке, слепо оканчивается в подкожной клетчатке крестцово-копчиковой области, открывается на коже одним или несколькими точечными отверстиями (первичный эпителиальный ход), и представляет собой узкую эпителиальную трубку. Продукты жизнедеятельности эпителия, выстилающего ход, периодически выделяются через точечные отверстия наружу. Закупорка или инфицирование выводных протоков, механическая травма приводят к задержке содержимого в просвете хода и способствуют возникновению воспаления. В результате эпителиальный копчиковый ход расширяется, стенка его разрушается и в воспалительный процесс вовлекается окружающая клетчатка. Развившиеся при этом абсцесс или флегмона крестцово-копчиковой области иногда достигают значительной величины и могут вскрыться наружу в виде гнойного свища, который принято называть вторичным отверстием. <br /><br />В 25-50% случаев внутри эпителиального копчикового хода или возникшей на его месте кисты содержатся волосы, которые могут внедряться в боковые стенки и образовывать дополнительные ходы. Гнойник иногда достигает значительной величины и, как правило, прорывается через кожу, образуя наружное отверстие гнойного свища. <br />Различают неосложненный и осложненный гнойным процессом эпителиальный копчиковый ход.</p>",
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"description": "<p>Эритразма - это <span style=\"font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">хроническая бактериальная кожная инфекция, которая поражает верхний роговой слой кожи.</span></p>\r\n<p><span style=\"font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\"> </span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лица, страдающие от эритразмы, обладают повышенной концентрацией Corynebacterium minutissimum в верхних слоях эпидермиса.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инфицирование происходит при использовании предметов личной гигиены, принадлежащих носителю заболевания. Чаще всего заражение происходит во время незащищенных половых актов, посещения бань, саун, бассейнов, пеших прогулок по земле или песку.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Избыточное количество Corynebacterium minutissimum в эпидермисе не приводит к поражению волос или ногтевых пластин. Благоприятными условиями для жизнедеятельности возбудителя эритразмы являются:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">развившийся у ребёнка или взрослого гипергидроз;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">проживание пациента во влажном и жарком климате;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">травматические дерматиты;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">пренебрежение человека правилами личной гигиены;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">чрезмерно частое принятие душа, использование значительного количества мыла и моющих средств.</span></p>\r\n</li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Снижению защитных свойств кожи могут способствовать отдельные заболевания эндокринной системы и пищеварительного тракта.</span></p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кожа вместе со слизистой оболочкой образует первую линию защиты против инфекций. Кератинизация (отмирание и ороговение клеток эпидермиса) и сухость ограничивают размножение микроорганизмов, что поддерживается низким pH поверхности кожи и ограничивают колонизацию кожи комменсалами (микроорганизмами, которые в норме живут совместно с человеком, извлекают из этого пользу и не причиняют вреда). Микроорганизмам необходимо преодолеть эти защитные механизмы путём проникновения через неповреждённый эпидермис, либо путём растворения клеток кератиноцитов, также они могут проникнуть через механические микротравмы на коже.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Роговой слой кожи состоит в основном из кератина, смешанного с секретируемыми липидами придатков кожи, которые используются в качестве субстрата для метаболизма бактерий, паразитирующих на коже.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При повышении уровня количества липидов начинается активное размножение комменсалов, что приводит к воспалительному процессу. В результате таких предрасполагающих факторов, как высокая температура, влажность в результате мацерации кожи, коринебактерии проникают в верхнюю треть рогового слоя, где усиленно размножаются. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Бактерии проникают в межклеточные пространства и внутрь клеток, растворяя кератин фибрилл, вызывая утолщение рогового слоя.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В процессе жизнедеятельности бактерии синтезируют копропорфирин III (пигмент, образующийся в результате обменных процессов), который накапливается в коже, вызывая кораллово-красное свечение очагов поражения при осмотре лампой Вуда.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагностика заболевания происходит в несколько этапов:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">сбор анамнеза, осмотр больного и обследование пораженных участков кожи, соскоб;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">облучение пораженной кожи лампой Вуда (должно присутствовать свечение пигмента, выработанного болезнетворными микроорганизмами);</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">микроскопия соскоба тканей из очага эритразмы (обнаружение цепочек или групп кокковидных клеток);</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre; margin-left: 36pt;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">бактериальный посев соскоба для выявления возбудителя (болезнь необходимо дифференцировать с псориазом, рубромикозом, микробной экземы, паховой эпидермофитией, кандидозом кожи, контактным и перианальным дерматитом, а также с разноцветным и розовым лишаем).</span></p>\r\n</li>\r\n</ul>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение эритразмы предусматривает использование наружных средств для отшелушивания и дезинфекции кожи - эритромициновой и серно-дегтярной мази.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Мазь втирают в проблемные зоны дважды в сутки на протяжении недели. Кроме того, для обработки инфекционных очагов используют 5%-й салициловый спирт, 3%-й салицилово-резорциновый спирт, 2%-й спиртовой раствор йода. В случае обширного поражения кожных покровов врач-дерматолог назначает антибиотики для приема внутрь.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">С целью ликвидации покраснения и отечности применяют водные растворы анилиновых красителей.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Весьма полезны физиотерапевтические процедуры с ультрафиолетом, а также ежедневный загар в течение 30 - 40 минут под утренним и вечерним солнцем.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для успешного лечения эритразмы следует провести дезинфекцию постельного белья, одежды, обуви и прочих предметов обихода. Одежду и нижнее белье необходимо ежедневно стирать и проглаживать утюгом. С целью предупреждения рецидивов болезни рекомендуется на протяжении одного месяца регулярно протирать кожные складки 2%-м раствором салицилового спирта или 1-2% раствором камфорного спирта, а затем наносить на них тальк или борную кислоту.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основная мера профилактики этого заразного заболевания – соблюдение гигиены. Чтобы не создавать на коже благоприятной среды для размножения микроорганизмов, следует регулярно принимать душ и насухо вытирать кожные складки. Особенно подмышки, паховую область, шею и живот.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Одной из важных мер профилактики является снижение потливости. Это достигается сменой синтетической одежды на натуральную, использованием дезодорантов, и ежедневными гигиеническими процедурами.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Также стоит помнить, что вся новая одежда перед ноской должна быть выстирана и проглажена.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Базовые проявления эритразмы — шелушащиеся пятна, появляющиеся на кожных покровах. Первичные очаги окрашены в светло-коричневый, красный, бурый или жёлтый цвет. Диаметр пятен не превышает 50 мм.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Постепенно высыпания увеличиваются в размерах. Несколько мелких очагов могут сливаться в один крупный участок эритразмы, который покрыт мелкими чешуйками. Спустя несколько недель в центре поражённого участка формируется пигментированное образование бурого цвета (в редких случаях происходит побледнение окраски).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пятна появляются рядом с крупными кожными складками. Мужчины могут столкнуться с образованием обширного очага в паховой области, промежности и на внутренних поверхностях бёдер. Женщины страдают от формирования пятнистых участков в складках под молочными железами и в подмышечных впадинах. Люди с избыточным весом могут обнаружить пятна на животе и ягодицах.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В большинстве клинически регистрируемых случаев эритразмы пациенты не испытывают никаких субъективных ощущений. В редких случаях дети и взрослые жалуются на умеренный зуд. Отсутствие специфических симптомов приводит к незаметному течению заболевания. Патология может развиваться длительное время с постоянным чередованием ремиссий и обострений. </span></p>",
"image": "http://api.symptomd.ru/storage/Eritrazma_2.jpg",
"image_alt": null,
"standard_type": 0,
"danger": 1,
"published": 1,
"parent": 6721,
"block_rubric": 120,
"standards": []
},
{
"id": 11937,
"symptoms": [],
"alternative_names": [],
"complications": [],
"medicine_branches": [],
"who": [
{
"id": 14131,
"gender": 2,
"diseased": 631634,
"deaths": 24562,
"danger": 0.09,
"mortality": 9.04,
"outpatient_days": 9,
"hospital_days": 202,
"diseased_1": 48884,
"diseased_1_4": 41174,
"diseased_5_9": 22427,
"diseased_10_14": 13141,
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},
"code": "L10",
"name": "Пузырчатка [пемфигус]",
"icd_name": "Пузырчатка [пемфигус]",
"gender": 0,
"age_min": 18,
"age_max": 100,
"cause": [
3,
0
],
"periodicity": 4,
"slug": "l10_puzyrchatka_pemfigus",
"lead": "хроническое заболевание аутоиммунной природы, которое характеризуется появлением пузырей на клинически здоровой коже и слизистых оболочках.",
"description": "Не заразное, крайне тяжелое заболевание кожи.",
"etiology": "<p>Наиболее вероятными причиной пузырчатки являются нарушения аутоиммунных процессов, в результате чего клетки организма становятся для иммунной системы антителами. Нарушение антигенной структуры клеток эпидермиса происходит под воздействием внешних факторов, в частности воздействие ретровирусов и агрессивных условий окружающей среды.</p>",
"pathogenesis": "<p>Повреждающее действие на клетки эпидермиса и выработка специфических антигенов приводит к нарушению связи между клетками в результате чего и образуются пузыри.</p>",
"diagnostics": "<p>Диагностика пузырчатки осуществляется врачом-дерматологом и основана на совокупности результатов осмотра, цитологического, гистологического и иммунологического обследований. При всех формах заболевания отмечают отложение иммуноглобулинов G в поверхностных слоях кожи.</p>",
"treatment": "<p align=\"justify\">Все пациенты больные пузырчаткой должны находиться на диспансерном наблюдении у дерматолога, рекомендован щадящий режим работы, отсутствие физических нагрузок и избегание инсоляции. Частая смена нательного и постельного белья предотвращает присоединение вторичной инфекции.</p>\r\n<p> </p>\r\n<p align=\"justify\">Показано назначение глюкокортикостероидов сразу в высоких дозах, так как иначе терапевтического эффекта достигнуто не будет, после купирования острых проявлений пузырчатки дозировки гормональных препаратов постепенно снижают до минимально эффективных. В лечении пузырчатки применяют методы экстракорпоральной гемокоррекции: гемосорбцию, криоаферез и мембранный плазмаферез. </p>\r\n<p> В качестве местного лечения пузырчатки используют анилиновые красители и неагрессивные антисептические растворы.</p>\r\n<p>Прогноз пузырчатки всегда неблагоприятный, так как в случае отсутствия адекватного лечения смерть пациентов наступает довольно быстро от присоединившихся осложнений. Длительная гормональная терапия в высоких дозах повышает риск возникновения побочных эффектов, но при отказе от глюкокортикостероидов пузырчатка начинает рецидивировать</p>",
"prevention": "",
"clinical_picture": "<p align=\"justify\">Пузырчатка имеет длительное волнообразное течение, и отсутствие адекватного лечения приводит к нарушению общего состояния пациента.</p>\r\n<p> </p>\r\n<p align=\"justify\">При вульгарной форме пузырчатки пузыри локализуются по всему телу, имеют разный размер и наполнены серозным содержимым, при этом покрышка на пузырях вялая и тонкая.</p>\r\n<p> </p>\r\n<p align=\"justify\">Дебютирует вульгарная пузырчатка как правило на слизистой рта и носа, а потому пациенты длительно и безуспешно получают терапию у стоматологов и отоларингологов. На этой стадии пузырчатки пациенты предъявляют жалобы на боль во время приема пищи и при разговоре, гиперсаливацию и специфический неприятный <a href=\"/symptom/zapah_izo_rta/\" title=\"Перейти на страницу симптома Запах изо рта\">запах изо рта</a>. Продолжительность этого периода от трех месяцев до года, после чего пузырчатка принимает распространенный характер и в воспалительный процесс вовлекаются кожные покровы.</p>\r\n<p>Иногда пациенты не замечают наличие пузырей из-за их небольшого размера и тонкой покрышки, пузыри вскрываются быстро, а потому основные жалобы больных пузырчаткой на данном периоде – это болезненные <a href=\"/symptom/izmeneniya_struktury_kozhi/\" title=\"Перейти на страницу симптома Изменения структуры кожи\">эрозии</a>. Проводится длительная и безуспешная терапия стоматитов, прежде чем диагностируют пузырчатку. Пузыри, которые локализуются на коже, имеют тенденцию к самопроизвольному вскрытию с обнажением эрозированной поверхности и с остатками покрышки, которая ссыхается в корки.</p>\r\n<p> <a href=\"/symptom/izmeneniya_struktury_kozhi/\" title=\"Перейти на страницу симптома Изменения структуры кожи\">Эрозии</a> при пузырчатке ярко-розовые, с гладкой глянцевой поверхностью, отличаются от эрозий при других заболеваниях склонностью к периферическому росту и к генерализации с формированием обширных очагов поражения. Если пузырчатка принимает такое течение, то общее состояние пациента ухудшается, развивается интоксикация, присоединяется вторичная инфекция и без должного лечения такие пациенты умирают.</p>\r\n<p> При вульгарной пузырчатке синдром Никольского положительный в очаге поражения и порой на здоровой коже - при незначительном механическом воздействии происходит отслойка верхнего слоя эпителия.</p>",
"image": "http://api.symptomd.ru/storage/837faab8994a265991352d359212a5a0_ra0aeDL.jpg",
"image_alt": "Пузырчатка",
"standard_type": 1,
"danger": 56,
"published": 1,
"parent": null,
"block_rubric": 121,
"standards": []
}
]
}