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"code": "F25",
"name": "Шизоаффективные расстройства",
"icd_name": "Шизоаффективные расстройства",
"gender": 0,
"age_min": 10,
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"slug": "f25_shizoaffektivnye_rasstroystva",
"lead": "Нарушение здоровья, относящееся к группе шизофрения, шизотипические состояния и бредовые расстройства",
"description": " \r\n\r\nШизоаффективное расстройство – это биполярное расстройство психики, которое отличает сочетание двух отклонений, а именно аффективного расстройства и шизофрении. ",
"etiology": "<p>В развитии заболевания имеет значение генетический фактор. У пациентов с данной патологией довольно часто можно обнаружить родственников как с шизофренией, так и с биполярным аффективным расстройством; </p>\r\n<p>Среди больных шизоаффективным расстройством преобладают одинокие люди, чьи близкие живут далеко и не оказывают им поддержку; </p>\r\n<p>Нередко присутствует связь между злоупотреблением спиртными напитками, употреблением психоактивных веществ и развитием шизоидных отклонений, что при этом первично, а что вторично — пока изучается. Также существует мнение о близости данного вида расстройств к эпилепсии. </p>\r\n<p>Довольно часто приступы болезни возникают под действием влияния извне, когда удается установить связь между психотравмирующей ситуацией и обострением болезни. </p>",
"pathogenesis": "<p>У таких больных нарушается обмен веществ в головном мозге, что является причиной нарушений. Между клетками мозга теряется старая «правильная» цепочка передачи информации, и сообщения между нейронами происходит совершенно в хаотичном порядке. Это и вызывает всю последующую симптоматику. Запустить болезнь в действие может плохое и негативное социальное окружение, резкие изменения в жизни человека, стрессы, замкнутость от социума на длительное время или же тяжелые вирусные инфекции, которыми переболел человек. <br class=\"SCXW85501203\" /> </p>",
"diagnostics": "<p>Диагноз шизоаффективное расстройство ставится при условии наличия в одном эпизоде: Не менее двух характерных признаков депрессивного эпизода: </p>\r\n<ul>\r\n<li>сниженная способность к вниманию и сосредоточению; </li>\r\n<li>снижение самооценки и уверенности; </li>\r\n<li>навязчивые идеи уничижения и виновности; </li>\r\n<li>пессимизм и мрачность по отношению к своему будущему; </li>\r\n<li>нарушения сна и аппетита; </li>\r\n<li>самоповреждение и попытки суицида </li>\r\n</ul>\r\n<p>Не менее одного-двух типичных признаков шизофрении: </p>\r\n<ul>\r\n<li>вкладывание или отнятие мыслей, их трансляция или вещание (эхо мыслей); </li>\r\n<li>бред влияния, воздействия, восприятия или пассивности, который относится к действиям, мыслям, телу (в том числе отдельным его частям); </li>\r\n<li>слуховые галлюцинации (комментирующие или осуждающие голоса, обсуждающие или осуждающие его поведение), другие виды галлюцинаций, например, «разговаривающие» части тела; </li>\r\n<li>стойкие бредовые идеи, которые не характерны для данной культуры, религиозной принадлежности и имеют невозможный и неадекватный характер. Отождествление себя с историческими, политическими или религиозными деятелями, наличие сверхспособностей (общение с инопланетянами, управление погодой). </li>\r\n</ul>",
"treatment": "<p>Для лечения шизоаффективного расстройства назначают следующие лекарственные препараты. </p>\r\n<p>Успокоительные средства </p>\r\n<p>Нейролептики назначаются, чтобы подавить психотические симптомы, такие как бред, галлюцинации и паранойя. К нейролептикам относятся такие препараты как клозапин, рисперидон и оланзапин. </p>\r\n<p>Стабилизаторы настроения </p>\r\n<p>Стабилизаторы настроения назначаются при шизоаффективном расстройстве биполярного типа. Они помогают держать под контролем аффективную сторону заболевания, смягчая периоды мании и депрессии, характерные для биполярного расстройства. Наиболее распространёными стабилизаторами настроения являются препараты лития. </p>\r\n<p>Антидепрессанты </p>\r\n<p>При шизоаффективном расстройстве депрессивного типа назначаются антидепрессанты. Они помогают побороть чувство безнадёжности, печали, нормализуют сон и улучшают концентрацию внимания. Наиболее часто назначаются циталопрам, флуоксетин и эсциталопрам. </p>\r\n<p>Из немедикаментозной терапии часто применяются следующие методы </p>\r\n<p>Психотерапия </p>\r\n<p>Выстраивание доверительных отношений с врачом в ходе психотерапии помогает пациенту лучше понять свою болезнь и с большей уверенностью смотреть в будущее. Сеансы психотерапии учат пациента ставить реальные жизненные цели, решать проблемы и выстраивать взаимоотношения. Пациент может быть обучен новым поведенческим стратегиям, которые будут способствовать более эффективному общению дома и на работе. </p>\r\n<p>Семейная или групповая терапия </p>\r\n<p>Лечение может быть более эффективным, если люди, страдающие шизоаффективным расстройством, будут иметь возможность обсудить свою жизнь и проблемы с людьми, страдающими таким же заболеванием. Появление группы поддержки также может уменьшить социальную изоляцию больных и обеспечить постоянный контроль за ними. </p>\r\n<p> </p>",
"prevention": "<p>Специфических методов профилактики нет, так как это заболевание не имеет чёткой этиологии. Снизить риск его развития можно, если вести правильный образ жизни не только в физиологическом, но и психологическом понимании. При первых же проявлениях вышеописанной клинической картины следует обращаться за консультацией к психиатру. </p>",
"clinical_picture": "<p>В большинстве случаев шизоаффективному приступу предшествует психическая травма. </p>\r\n<p>Для общей клинической картины патологии характерно наличие признаков, общих для аффективного расстройства и шизофрении. Эти симптомы включают: </p>\r\n<ul>\r\n<li>повышенную возбудимость, которая на фоне агрессивности приводит к нервному срыву; </li>\r\n<li>нарушения сна - повышенная сонливость или бессонница; </li>\r\n<li>пониженный уровень аппетита; </li>\r\n<li>быструю утомляемость и физическую усталость, даже при незначительных нагрузках; </li>\r\n<li>потерю интереса к происходящему вокруг и к интересовавшим ранее занятиям; </li>\r\n<li>развитие комплекса вины, неполноценности, которые с течением времени переходят в чувство глубокой безнадежности; мысли о смерти; </li>\r\n<li>затуманенность умственной деятельности, интеллекта; </li>\r\n<li>невозможность сконцентрироваться на каком-либо процессе; </li>\r\n<li>стремление к определенному виду деятельности, обычно – сексуального характера; </li>\r\n<li>изменение темпа речи в сторону ускорения при определенных обстоятельствах; </li>\r\n<li>в период обострений – опасное поведение в социуме; </li>\r\n<li>устойчивую тенденцию к снижению мыслительного труда, интеллекта, проявляющуюся по типу классического слабоумия; </li>\r\n<li>бредовые идеи и высказывания; </li>\r\n<li>слуховые галлюцинации, возникновение которых связано с повышенными эмоциональными переживаниями или переутомлением; </li>\r\n<li>периодическое странное, нелогичное, некорректное поведение, сопровождающееся монотонным бредом; </li>\r\n<li>нелогичные эмоции– смех на похоронах. </li>\r\n</ul>",
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"description": "Шизотипическим считается расстройство, в симптоматике которого проявляются мыслительная, поведенческая, эмоциональная и социальная аномалии, характерные для шизофрении, но отличные от нее своим менее выраженным характером. ",
"etiology": "<p>К предполагаемым причинам причинам шизотипического расстройства относятся: </p>\r\n<ul>\r\n<li>Наследственная предрасположенность, провоцирующая повышенную активность дофамина; </li>\r\n<li>Нехватка внимания в детском возрасте; </li>\r\n<li>Частые стрессовые ситуации; </li>\r\n<li>Патология беременности. </li>\r\n</ul>",
"pathogenesis": "<p>У таких больных нарушается обмен веществ в головном мозге, что является причиной нарушений. Между клетками мозга теряется старая «правильная» цепочка передачи информации, и сообщения между нейронами происходит совершенно в хаотичном порядке. Это и вызывает всю последующую симптоматику. Запустить болезнь в действие может плохое и негативное социальное окружение, резкие изменения в жизни человека, стрессы, замкнутость от социума на длительное время или же тяжелые вирусные инфекции, которыми переболел человек. <br class=\"SCXW224023875\" /> </p>",
"diagnostics": "<p>Критерии постановки диагноза шизотипического расстройства по МКБ-10: </p>\r\n<ul>\r\n<li>Эмоциональная холодность, отрешенность. </li>\r\n<li>Эксцентричность, странность поведения. </li>\r\n<li>Плохой контакт с другими людьми. </li>\r\n<li>Странные убеждения или магическое мышление, влияющие на поведение и несовместимые с субкультуральными нормами. </li>\r\n<li>Подозрительность или параноидные идеи. </li>\r\n<li>Навязчивые размышления, часто с сексуальным или агрессивным содержанием. </li>\r\n<li>Необычные феномены восприятия, включая соматосенсорные (телесные) или другие иллюзии, деперсонализация или дереализация. </li>\r\n<li>Обстоятельное, детализированное или стереотипное мышление, проявляющееся странной, вычурной речью. </li>\r\n<li>Эпизоды с иллюзиями, слуховыми или другими галлюцинациями, бредоподобными идеями. </li>\r\n</ul>\r\n<p>На протяжении минимум двух лет должны обнаруживаться хотя бы 4 признака из вышеперечисленных. </p>",
"treatment": "<p>Для лечения шизотипического расстройства назначают следующие лекарственные препараты: </p>\r\n<p>Успокоительные средства </p>\r\n<p>Нейролептики назначаются, чтобы подавить психотические симптомы, такие как бред, галлюцинации и паранойя. К нейролептикам относятся такие препараты как клозапин, рисперидон и оланзапин. </p>\r\n<p>Стабилизаторы настроения </p>\r\n<p>Стабилизаторы настроения назначаются при шизоаффективном расстройстве биполярного типа. Они помогают держать под контролем аффективную сторону заболевания, смягчая периоды мании и депрессии, характерные для биполярного расстройства. Наиболее распространёными стабилизаторами настроения являются препараты лития. </p>\r\n<p>Антидепрессанты </p>\r\n<p>При шизоаффективном расстройстве депрессивного типа назначаются антидепрессанты. Они помогают побороть чувство безнадёжности, печали, нормализуют сон и улучшают концентрацию внимания. Наиболее часто назначаются циталопрам, флуоксетин и эсциталопрам. </p>\r\n<p>Из немедикаментозной терапии часто применяются следующие методы </p>\r\n<p>Психотерапия </p>\r\n<p>Выстраивание доверительных отношений с врачом в ходе психотерапии помогает пациенту лучше понять свою болезнь и с большей уверенностью смотреть в будущее. Сеансы психотерапии учат пациента ставить реальные жизненные цели, решать проблемы и выстраивать взаимоотношения. Пациент может быть обучен новым поведенческим стратегиям, которые будут способствовать более эффективному общению дома и на работе. </p>\r\n<p>Семейная или групповая терапия </p>\r\n<p>Лечение может быть более эффективным, если люди, страдающие шизоаффективным расстройством, будут иметь возможность обсудить свою жизнь и проблемы с людьми, страдающими таким же заболеванием. Появление группы поддержки также может уменьшить социальную изоляцию больных и обеспечить постоянный контроль за ними. </p>",
"prevention": "<p>Специфических методов профилактики нет, так как это заболевание не имеет чёткой этиологии. Снизить риск его развития можно, если вести правильный образ жизни не только в физиологическом, но и психологическом понимании. При первых же проявлениях вышеописанной клинической картины следует обращаться за консультацией к психиатру. </p>",
"clinical_picture": "<p>Пациенты с имеющиеическим расстройством личности отличаются бессвязной манерой разговоров, не имеющей логического начала и конца. Для них характерно общаться обрывками фраз, перескакивать с одной темы на другую или же повторять одно и тоже по несколько раз. Слыша такую речь, окружающие с трудом ее воспринимают или не понимают вовсе, что такой больной хочет сказать. </p>\r\n<p>Коммуникативные навыки с внешним миром возможны только с теми людьми, которые знают о заболевании и смогли адаптироваться к странному поведению. Незнакомые и чужие могут вызвать у больных агрессию, гнев, приступ паники, раздражительность. </p>\r\n<p>При шизотипическом расстройстве личности наблюдается общение с невидимыми людьми. Чаще всего пациенты разговаривают сами с собой или с воображаемыми персонажами. Последние могут быть как реальными, так и выдуманными. Такие периоды общения характеризуются открытостью со стороны больного. Он может плакать, кричать, пытаться что-то доказать несуществующему рядом человеку; может делиться всеми своими переживаниями и страхами, которые связаны с чем-то, что человек пережил далеко в прошлом, в юности или детстве. Это может быть все, что угодно: изнасилование, издевательства, насмешки со стороны взрослых и детей и т. д. </p>\r\n<p>Для людей с шизотипическим расстройством характерно отчуждение от социума и постоянное, нескрываемое желание быть одним. Сам же человек с таким заболеванием не считает себя одиноким. </p>\r\n<p>Постоянное изменение в настроении также является одним из симптомов заболевания. Вспышки гнева безо всяких на то причин, ярость, плач, бросание рядом стоящих предметов обихода — все это характерно для людей с шизотипическим расстройством. </p>\r\n<p>Навязчивость идей вплоть до параноидального синдрома на фоне постоянного беспокойства и подозрительности ко всему происходящему вокруг. </p>\r\n<p> </p>",
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},
"code": "F20",
"name": "Шизофрения",
"icd_name": "Шизофрения",
"gender": 0,
"age_min": 15,
"age_max": 100,
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"slug": "f20_shizofreniya",
"lead": "психическая болезнь, проявляющаяся искажением мышления и восприятия",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Шизофрения — это психическое расстройство, при котором происходит распад процессов мышления и эмоциональных реакций. Заболевание не вызывает нарушений сознания и не изменяет многие интеллектуальные процессы, однако при длительном его протекании, нарушается восприятие, память и внимание.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причины возникновения точно не установлены. Большинство психиатров считают, что шизофрения является мультифакторным заболеванием, возникающим под влиянием ряда эндогенных и экзогенных воздействий. На риск развития шизофрении могут влиять:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Наследственная предрасположенность. При наличии близких родственников, страдающих этим заболеванием, риск развития шизофрении увеличивается до 10%, то есть, примерно в 20 раз по сравнению со средним риском по популяции. Вместе с тем, 60% больных имеют неотягощенный семейный анамнез.</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Перинатальные вредности. К числу факторов, повышающих риск развития шизофрении, относят внутриутробные инфекции, осложненные роды и время рождения.</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Социальные условия. Отмечают устойчивую корреляцию распространенности шизофрении с рядом социальных факторов, в том числе – уровнем урбанизации (горожане болеют чаще сельских жителей), бедностью, неблагоприятными условиями жизни в детском возрасте и переездами семьи в связи с неблагоприятными социальными условиями.</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Стиль воспитания. Многие исследователи указывают на наличие ранних травмирующих переживаний, игнорирования жизненно важных потребностей, перенесенного в детстве сексуального или физического насилия. Большинство специалистов полагают, что риск возникновения шизофрении не зависит от стиля воспитания, при этом некоторые психиатры указывают на возможную связь болезни с грубыми нарушениями семейных отношений: пренебрежением, отвержением и отсутствием поддержки.</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Вредные зависимости. Шизофрения, алкоголизм, наркомания и токсикомания нередко тесно связаны между собой, однако отследить характер этих связей не всегда возможно. Существуют исследования, указывающие на связь обострений шизофрении с приемом стимуляторов, галлюциногенов и некоторых других психоактивных веществ. </span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Аномалии структуры головного мозга. У больных шизофренией выявляются отличия в анатомической структуре гиппокампа и височных долей, увеличение желудочков и снижение активности лобной доли, отвечающей за рассуждение, планирование и принятие решений. При этом исследователи отмечают, что перечисленные нарушения могут возникнуть вторично, под влиянием фармакотерапии, поскольку большинство пациентов, принимавших участие в исследованиях структуры головного мозга, ранее получали антипсихотические препараты.</span></li>\r\n</ul>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Патогенез шизофрении складывается из двух отчасти взаимосвязанных видов нарушений:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нейрохимические нарушения. Дисбаланс нейротрансмиттеров (веществ, обеспечивающих передачу нервных импульсов в синапсах).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Структурные изменения головного мозга. </span></li>\r\n</ul>\r\n<p> </p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагноз устанавливается на основании анамнеза, опроса больного, его друзей и родственников. Для постановки диагноза шизофрения необходимо наличие одного или более критериев первого ранга и двух или более критериев второго ранга, определенных МКБ-10.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">1. К критериям первого ранга относят:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">слуховые галлюцинации;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">звучание мыслей;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">вычурные бредовые идеи;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">бредовые восприятия.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">2. В список критериев шизофрении второго ранга включают:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">кататонию,</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">прерывание мыслей,</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">постоянные галлюцинации (кроме слуховых),</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">нарушения поведения,</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">негативные симптомы.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Симптомы первого и второго ранга должны наблюдаться в течение месяца или более. Для оценки эмоционального состояния, психологического статуса и других параметров применяют различные тесты и шкалы, в том числе – тест Люшера, тест Лири, шкалу Карпентера, тест MMMI и шкалу PANSS.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение шизофрении включает в себя медикаментозную терапию, психотерапию и мероприятия по социальной реабилитации. Основой фармакотерапии являются препараты с антипсихотическим действием. В настоящее время предпочтение чаще отдают атипичным нейролептикам, которые реже вызывают позднюю дискинезию и, по мнению специалистов, могут уменьшать негативные симптомы шизофрении. Для уменьшения выраженности побочных эффектов нейролептики комбинируют с другими лекарственными препаратами, обычно – нормотимиками и бензодиазепинами. При неэффективности других методов назначают ЭСТ и инсулинокоматозную терапию.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">После редукции или исчезновения позитивной симптоматики больного шизофренией направляют на психотерапию. Для тренировки познавательных навыков, улучшения социального функционирования, помощи при осознании особенностей собственного состояния и приспособления к этому состоянию применяют когнитивно-поведенческую терапию. Для создания благоприятной семейной атмосферы используют семейную терапию. Проводят обучающие занятия для родственников больных шизофренией, оказывают психологическую поддержку близким пациентов.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Главные методы профилактики заключаются в своевременной диагностике психического заболевания. Чем раньше обратить внимание, тем лучших результатов можно добиться при лечении первого приступа. Не смотря на то, что шизофрения относится к неизлечимым заболеваниям, если терапия будет проведена правильно, то можно добиться стойкой и позитивной ремиссии, поэтому незамедлительно стоит обращаться к врачу при первых симптомах болезни.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Шизофрения развивается долго и незаметно для больного. Первые признаки появляются, когда человек уверен, что он вполне здоров.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ранние симптомы шизофрении:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #4c4c4c; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Изоляция от общества, нелюдимость.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #4c4c4c; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Равнодушие к себе, друзьям и родным.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #4c4c4c; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эмоциональная холодность.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #4c4c4c; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Постепенная потеря интереса ко всему, что волновало ранее.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6pt; font-family: Verdana; color: #4c4c4c; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нарушения сна.</span></p>\r\n</li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Когда болезнь прогрессирует, возникают общие симптомы и признаки шизофрении:</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"background-color: transparent; font-family: Verdana; font-variant-numeric: normal; font-variant-east-asian: normal; font-size: 7pt; vertical-align: baseline; white-space: pre-wrap;\">Психотические (позитивные):</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-variant-numeric: normal; font-variant-east-asian: normal; font-size: 7pt; vertical-align: baseline; white-space: pre-wrap;\">Галлюцинации — больной видит и слышит то, чего нет.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Бред — нелогичные убеждения, в которых больного невозможно переубедить.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Беспорядочное мышление — больной то говорит слишком быстро, то останавливается в середине мысли и при этом называет несуществующие слова.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Неестественность движений — больной шизофренией движется заторможено и замирает в неестественной позе или наоборот движется слишком быстро и дергано.</span></li>\r\n</ul>\r\n<p><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Негативные:</span></p>\r\n<ul style=\"margin-top: 0px; margin-bottom: 0px; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Невозможность выражения эмоций — больной постоянно выглядит подавленным и оторванным от реальности.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Нарушение мыслительного процесса — больной плохо усваивает информацию, не может сосредоточиться и все забывает.</span></li>\r\n</ul>",
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},
"code": "B65",
"name": "Шистосомоз [бильгарциоз]",
"icd_name": "Шистосомоз [бильгарциоз]",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
"5"
],
"periodicity": 1,
"slug": "b65_shistosomoz_bilgarcioz",
"lead": "Шистосомоз (бильгарциоз) - хронический гельминтоз, вызываемый трематодами рода Schistosoma, с преимущественным поражением мочеполовой системы и кишечника.",
"description": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Шистосомоз - это гельминтное заболевание, вызываемое кровяными сосальщиками-шистосомами; протекающее с токсико-аллергическими реакциями, поражением ЖКТ или мочеполовых органов.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основной причиной патологии являются трематоды, которые относятся к семейству Schistosomatidae.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Человек заражается шистосомозом при таких условиях</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">при единоразовом кратковременном контакте с водой температурой 20-20°С (особенно в сезон после дождей), зараженной яйцами шистосом, включая купание, прохождение брода, поэтому еще имеет название – «зуд пловца»;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">при использовании неочищенной некачественной воды для гигиенических процедур, стирки;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">выполнение сельскохозяйственных работ и рыболовства в эндемичных регионах;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">чрескожное ивазирование и проникновение церкарий происходит даже при абсолютной целостности кожных покровов.</span></li>\r\n</ul>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Наибольшее патогенетическое значение имеют шипы яиц шистосом, которые проникают через кровеносные и лимфатические сосуды, протыкают и повреждают различные ткани и органы, нарушая структуру мочевого пузыря, матки, простаты, печени, селезёнки, лёгких, сердца, желудка и кишечника.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Линия миграции личинок вызывает образование кожных инфильтратов, отечность спровоцирована лизисом эпидермальных клеток.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Токсико-аллергические реакции обычно обусловлены секретами желёз, вырабатываемых в процессе внедрения гельминтов, а также продуктами их жизнедеятельности и распада. В районе скопления паразитарных организмов и их яиц забивается просвет сосудов и проток, возникает варикозное расширение вен, а также возможно развитие кистозных и опухолевых образований. Процесс начинается с отложения яиц в подслизистом слое, что вызывает реакцию на инородное тело и скопление эозинофилов, гигантских клеток, а также гистиоцитов.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">В результате оболочки становятся гиперемированными и отечными, что в дальнейшем может привести к образованию специфической гранулемы – бильгарциомы или шистосомозной язвы, ткани которых претерпевают трансформацию в фиброзную ткань. Кроме того, отмершие яйца в некоторых случаях подвергаются кальцификации.</span></p>",
"diagnostics": "<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">микроскопическое исследование мочи и кала для выявления яиц шистосом</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">общий анализ мочи, который показывает лейкоцитурию, гематурию, протеинурию</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">серологические реакции РСК, ИФА, РНГА для определения антител к гельминтам</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">внутрикожные пробы с антигеном шистосом</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">УЗИ органов брюшной полости и забрюшинного пространства</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">обзорная и экскреторная урография</span></li>\r\n</ul>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"treatment": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Медикаментозная терапия шистосомоза эффективна в ранних стадиях, при отсутствии осложнений; в последних случаях нередко приходится прибегать к хирургическому лечению. При всех формах шистосомоза могут быть использованы антигельминтные средства: празиквантел, тинидазол, метрифонат. Успешность проведенной терапии оценивается на основании повторных гельминтологических исследований и серологических реакций. Хирургическая тактика обычно требуется при осложнениях мочеполового шистосомоза и может включать в себя операции на мочеточниках (при развитии стриктуры), удаление камней из мочевого пузыря и почек.</span></p>\r\n<p> </p>",
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}
]
}
