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"code": "P57",
"name": "Ядерная желтуха",
"icd_name": "Ядерная желтуха",
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"lead": "Нарушение здоровья, относящееся к группе геморрагические и гематологические нарушения у плода и новорожденного",
"description": "Ядерная желтуха – патологическое состояние, которое может возникнуть у новорожденных в результате билирубиновой интоксикации. Билирубин появляется в базальных ганглиях и ядрах ствола мозга, что приводит к нарушениям мозговых функций. ",
"etiology": "<p>Причинами ядерной желтухи могут стать следующие факторы: </p>\r\n<ul>\r\n<li>травмы головного мозга новорожденного; </li>\r\n<li>рождение раньше срока; </li>\r\n<li>недостаток ферментов, связывающих и выводящих билирубин; </li>\r\n<li>критическое нарушение обменных процессов у новорожденного; </li>\r\n<li>подкожные кровоизлияния у младенца; </li>\r\n<li>несовместимость резус-факторов матери и ребенка; </li>\r\n<li>серьезные патологии эндокринной системы матери; </li>\r\n<li>последствия приема сильнодействующих препаратов в период беременности; </li>\r\n<li>внутриутробные заболевания инфекционного характера; </li>\r\n<li>заболевания крови (матери и ребенка). </li>\r\n</ul>",
"pathogenesis": "<p>Заболевание развивается в связи с неспособностью организма новорожденного справиться с высокой концентрацией билирубина в крови. В норме реакции распада преобладают в первые дни жизни ребенка. Именно с этим связана физиологическая желтуха новорожденных, но в норме новорожденный справляется, и симптомы исчезают в течение нескольких дней или недель. Ядерная желтуха новорожденных характеризуется чрезмерной гипербилирубинемией, вследствие чего желчный пигмент начинает проходить через гематоэнцефалический барьер, окрашивая базальные ядра, ядра мозжечка и черепно-мозговых нервов в желтушный цвет. </p>\r\n<p>Для развития ядерной желтухи новорожденных необходимо множество условий. В частности, гематоэнцефалический барьер пропускает только свободный билирубин, то есть тот, который не связан с альбуминами и не подвергнутый конъюгации в печени. Значит, одним из факторов, способствующих развитию данного состояния, является гипопротеинемия (снижение белков-переносчиков). По этой причине симптомы чаще наблюдаются у детей с отеками, обширной кефалогематомой и т. д. Гипоксическое, инфекционное или травматическое повреждение мозга, имевшее место внутриутробно или в родах, значительно повышает проницаемость гематоэнцефалического барьера. То же касается недоношенности, когда мозговые структуры к моменту рождения остаются незрелыми. </p>\r\n<p>Гемолитическая болезнь новорожденных всегда является фактором повышенного риска ядерной желтухи новорожденных, поскольку в этом случае концентрация несвязанного билирубина быстрее всего достигает предельно допустимых значений и начинает превышать их, способствуя проникновению билирубина в вещество мозга. В таких случаях состояние развивается стремительно, часто с летальным исходом или глубокой инвалидизацией. </p>",
"diagnostics": "<p>Подозрение на ядерную желтуху возникает у врача еще на этапе визуального обследования новорожденного. Для подтверждения диагноза малышу назначаются лабораторные исследования и комплексное обследование внутренних систем организма. </p>\r\n<p>В некоторых случаях возникает необходимость в дополнительной консультации с профильными специалистами. </p>\r\n<p>Диагностика ядерной желтухи включает в себя следующие процедуры: </p>\r\n<ul>\r\n<li>определение уровня билирубина - при ядерной желтухе более 256 мкмоль/л у доношенных и более 171 мкмоль/л у недоношенных детей. </li>\r\n<li>пробы Кумбса - определение наличия антител к эритроцитам; </li>\r\n<li>биохимический анализ крови и мочи; </li>\r\n<li>общий анализ крови и мочи; </li>\r\n<li>УЗИ печени и селезенки; </li>\r\n<li>УЗИ головного мозга. </li>\r\n</ul>",
"treatment": "<p>Одним из этапов лечения ядерной желтухи новорожденных является фототерапия. Доказано, что излучение видимого спектра, особенно голубого цвета, способствует переходу токсичного непрямого билирубина в его изомер, который может выводиться печенью и почками без связывания с альбуминами крови. </p>\r\n<p>Если на фоне фототерапии уровень билирубина не снижается, показано переливание плазмы крови. Перелитые вместе с плазмой белки способствуют связыванию избыточного билирубина с последующим выведением его из организма. </p>\r\n<p>При неэффективности перечисленных методов лечения или стремительном прогрессировании симптоматики проводится обменно-заменное переливание крови. </p>\r\n<p>Применяются медикаменты, которые способствуют более быстрому выведению билирубина из тела младенца (препараты с желчегонным действием), энтеросорбенты. </p>\r\n<p>По показаниям проводится противосудорожная терапия.</p>",
"prevention": "<p>Профилактика состояния возможна в первые дни жизни. Профилактическая фототерапия проводится всем новорожденным с уровнем билирубина в крови выше 200 мкмоль/л, а также всем недоношенным новорожденным, детям, перенесшим внутриутробные инфекции, гипоксию плода, родовые травмы и др.</p>",
"clinical_picture": "<p>Гипербилирубинемия в первые дни и недели жизни заметна по желтой окраске кожных покровов и склер. В данном случае этот признак выражен в значительной степени. Кожа малыша имеет ярко-желтый оттенок уже в первый день жизни, в отличие от физиологической желтухи, которая развивается спустя 5-7 дней после рождения. Состояние чаще возникает остро в течение первой недели жизни. Выделяют две стадии: асфиксическую и спастическую. Первая стадия ядерной желтухи новорожденных характеризуется появлением приступов апноэ (ребенок не дышит) разной продолжительности. Мышечный тонус снижен, отмечаются отдельные подергивания. Ребенок вялый, плохо сосет. </p>\r\n<p>Спастическая стадия ядерной желтухи новорожденных представлена выраженным гипертонусом мышц разгибателей вплоть до опистотонуса. Голова ребенка непроизвольно резко запрокидывается назад, глаза закатываются вверх (симптом «заходящего солнца»). Дыхание нарушено, отмечаются частые приступы апноэ. Могут наблюдаться тонические судороги и пронзительный крик, связанный с напряжением мышц и отчасти с болевым синдромом, сопровождающим гипертонус. В тяжелых случаях ядерной желтухи новорожденных мышечное напряжение распространяется на конечности с их резким выпрямлением и пронацией сжатых кулачков. </p>\r\n<p>В течение нескольких недель состояние ребенка улучшается. Симптомы ослабевают, судороги и гипертонус отмечаются реже. Однако к концу первого года жизни в 80% случаев развивается мышечная ригидность, судороги вновь учащаются. Прогрессируют симптомы поражения черепно-мозговых нервов, что клинически проявляется снижением зрения и слуха. Часто развивается косоглазие и тугоухость. Массивное поражение нейронов неизбежно отражается на умственном развитии. У детей, перенесших ядерную желтуху новорожденных, впоследствии нередко диагностируется синдром дефицита внимания с гиперактивностью (СДВГ), а также умственная отсталость. </p>",
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},
"code": "K26",
"name": "Язва двенадцатиперстной кишки",
"icd_name": "Язва двенадцатиперстной кишки",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
3
],
"periodicity": 4,
"slug": "k26_yazva_dvenadcatiperstnoy_kishki",
"lead": "Нарушение здоровья, относящееся к группе болезни пищевода, желудка и двенадцатиперстной кишки",
"description": " \r\n\r\nЯзва двенадцатиперстной кишки относится к хроническим заболеваниям и характеризуется образованием на слизистой органа язвенного дефекта. Течение болезни волнообразное с периодами ремиссии, когда симптомы практически отсутствуют, и периодами обострения. ",
"etiology": "<p>Наиболее существенным фактором в развитии язвенной болезни желудка и двенадцатиперстной кишки считается бактерия Helicobacter Pylori. Этот микроорганизм обнаруживается у восьми человек из десяти, однако, далеко не у всех он провоцирует развитие язвы. </p>\r\n<p>Помимо Хеликобактер на формирование язвы оказывают влияние следующие факторы: </p>\r\n<ul>\r\n<li>острое и хроническое психоэмоциональное перенапряжение; </li>\r\n<li>злоупотребление алкогольными напитками, курение; </li>\r\n<li>алиментарный фактор (систематическое употребление грубой, пряной, чрезмерно горячей или холодной пищи провоцирует желудочную секрецию, избыточную продукцию соляной кислоты); </li>\r\n<li>прием гастротропных лекарственных средств, оказывающих повреждающее воздействие на внутреннюю оболочку органа (нестероидные противовоспалительные лекарственные средства, производные салициловой кислоты, глюкокортикостероидные гормоны); </li>\r\n<li>хронические заболевания органов ЖКТ (цирроз, хронический панкреатит); </li>\r\n<li>давление на слизистую оболочку объемных новообразований, локализующихся в подслизистом слое; острая гипоксия (травмы, массивные ожоги, коматозное состояние); </li>\r\n<li>обширные оперативные вмешательства (продукция соляной кислоты, одного из факторов агрессии, в течение 10 дней после операции возрастает до 4 раз); </li>\r\n<li>выраженный диабетический кетоацидоз; </li>\r\n<li>профессиональные вредности (соли тяжелых металлов, пестициды, пары лакокрасочных материалов, ароматические углеводороды). </li>\r\n</ul>\r\n<p> </p>",
"pathogenesis": "<p>Развитие язвы (дефекта) слизистой оболочки двенадцатиперстной кишки, происходит по 2 основным механизмам: </p>\r\n<ol>\r\n<li>агрессивного действия соляной кислоты на слизистую оболочку, в результате повышенной кислотности. Попадание в двенадцатиперстную кишку кислого желудочного содержимого, приводит к воспалению участков её слизистой, и образование дефекта в виде язвы; </li>\r\n<li>инфекционный фактор (Helicobacter Pylori), бактерия обладающая сродством к эпителию органов пищеварительной системы (желудок, двенадцатиперстная кишка). Инфекции Helicobacter Pylori попадая в пищеварительный тракт, может оставаться в течение многих лет, закрепляясь своими жгутиками к стенке слизистой, не вызывая ни каких клинических проявлений. По мере размножения, происходит выделение бактерией вредных веществ, которые приводят к смерти клеток слизистой двенадцатиперстной кишки, с последующим развитием дефекта. Так же, Helicobacter Pylori повышает кислотность, с помощью выделения аммиака. </li>\r\n</ol>",
"diagnostics": "<p>Обследование включает: </p>\r\n<ul>\r\n<li>Клинический анализ крови. Клинический анализ крови при неосложненном течении язвенной болезни чаще всего остается без существенных изменений. Иногда отмечается незначительное повышение содержания гемоглобина и эритроцитов, но может обнаруживаться и анемия, свидетельствующая о явных или скрытых кровотечениях. Лейкоцитоз и ускорение СОЭ встречаются при осложненных формах язвенной болезни. </li>\r\n</ul>\r\n<ul>\r\n<li>Анализ кала на скрытую кровь. </li>\r\n<li>Исследование кислотообразующей функции желудка, которое проводится с помощью внутрижелудочной рН-метрии (в последние годы — с помощью суточного мониторирования внутрижелудочного рН). При язвах двенадцатиперстной кишки и пилорического канала обычно отмечаются повышенные (реже — нормальные) показатели кислотной продукции. </li>\r\n</ul>\r\n<ul>\r\n<li>Рентгенологический метод исследования. При рентгенологическом исследовании обнаруживаются рубцово-язвенная деформация луковицы двенадцатиперстной кишки, нарушения гастродуоденальной моторики. </li>\r\n</ul>\r\n<ul>\r\n<li>Эндоскопический метод исследования. Эндоскопическое исследование подтверждает наличие язвенного дефекта, уточняет его локализацию, глубину, форму, размеры, позволяет оценить состояние дна и краев язвы, выявить сопутствующие изменения слизистой оболочки. </li>\r\n</ul>\r\n<ul>\r\n<li>Биопсия с последующим гистологическим исследованием полученного материала. Данное исследование дает возможность исключить злокачественный характер язвенного поражения. </li>\r\n</ul>\r\n<ul>\r\n<li>Исследования наличия в слизистой оболочке желудка Helicobacter pylori. </li>\r\n<li>Электрогастроэнтерография и антродуоденальная манометрия — позволяют выявить нарушения гастродуоденальной моторики. </li>\r\n</ul>",
"treatment": "<p>Все больные язвенной болезнью, должны обязательно соблюдать режим питания, придерживаться диеты, по возможности исключить нервные стрессы, отказаться от алкогольных напитков и курения. Еда для больных язвенной болезнью должна быть мелко измельчённой (не грубой), тёплой (не горячей и не холодной), не солённой, не жирной и не острой. Больной должен питаться около 5 раз в день, маленькими порциями, общая суточная калорийность, должна составлять около 2000 ккал. Еда должна быть, в варёном виде или приготовленная на пару. </p>\r\n<p>Группы медикаментов, которые используются для лечения язвы двенадцатиперстной кишки:</p>\r\n<p> </p>\r\n<ol>\r\n<li>Антибиотики, применяются с целью эрадикации (уничтожения) хеликобактерной инфекции; </li>\r\n<li>Для устранения боли путём снижения секреции соляной кислоты применяются: </li>\r\n</ol>\r\n<p> </p>\r\n<ul>\r\n<li>Препараты висмута, обладают как вяжущим механизмом для слизистой желудка, так и бактерицидным действием против Helicobacter Pylori; </li>\r\n<li>Ингибиторы протоновой помпы; </li>\r\n<li>Ингибиторы Н2 – рецепторов.</li>\r\n</ul>\r\n<p> 3. Препараты, устраняющие боль, путём образования защитной плёнки на слизистой двенадцатиперстной кишки (антациды). </p>\r\n<p>В ряде экстренных случаев, таких как перфорация язвы, сильное желудочно-кишечное кровотечение, непроходимость пилорического канала, прибегают к оперативному лечению. В данном случае проводят два вида операций: </p>\r\n<ol>\r\n<li>Ваготомия — пересечение нервов, стимулирующих желудочную секрецию и приводящих к рецидивам язвенной болезни. </li>\r\n<li>Резекция желудка — это удаление 2/3 желудка и соединение оставшейся его части с кишечником, зачастую при проведении резекции выполняют также ваготомию. </li>\r\n</ol>",
"prevention": "<p><strong></strong></p>\r\n<p>Меры профилактики развития язвенной болезни двенадцатиперстной кишки: </p>\r\n<ul>\r\n<li>своевременное выявление и лечение хеликобактерной инфекции; </li>\r\n<li>нормализация режима и характера питания; </li>\r\n<li>отказ от курения и злоупотребления алкоголем; </li>\r\n<li>контроль за принимаемыми лекарственными средствами; </li>\r\n<li>гармоничная психологическая обстановка, избегание стрессовых ситуаций.</li>\r\n</ul>",
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},
"code": "K25",
"name": "Язва желудка",
"icd_name": "Язва желудка",
"gender": 0,
"age_min": 20,
"age_max": 100,
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"0",
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],
"periodicity": 3,
"slug": "k25_yazva_zheludka",
"lead": "хроническое воспаление стенок желудка с образованием эрозий слизистой оболочки",
"description": "<p>Язва желудка - это <span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">хроническое рецидивирующее заболевание, характеризуется наличием язвенных дефектов слизистой оболочки желудка.</span></p>",
"etiology": "<p>Повреждение слизистой оболочки с образованием язв, эрозий и воспаления связывают с преобладанием факторов агрессии (соляная кислота, пепсин, желчные кислоты) над факторами защиты слизистой оболочки. Важную роль имеет инфицирование Helicobacter pylori. Эти микроорганизмы способны вызывать <a title=\"Перейти на страницу симптома воспаление\" href=\"/symptom/vospalenie/\">воспаление</a> слизистой оболочки, разрушая при этом местные факторы защиты и усиливая кислотность.К факторам, способствующим возникновению заболевания относят:<br />- длительное нервно-эмоциональное перенапряжение;<br />- генетическую предрасположенность;<br />- наличие хронического гастрита или дуоденита;<br />- нарушение режима питания;<br />- употребление крепких спиртных напитков и курение;<br />- употребление некоторых лекарственных препаратов (ацетилсалициловая кислота, индометацин и др.).</p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Единого механизма, обусловливающего возникновение боли у лиц, страдающих язвенной болезнью, нет. Боль может быть вызвана раздражением нервных окончаний дна язвы кислым содержимым или пищей. Стойкое повышение кислотности, перевозбуждение блуждающего нерва также могут способствовать возникновению спазмов.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Большая роль в язвообразовании отводится инфекции H. pylori, которая действует двояко: с одной стороны — бактерии прикрепляются к клеткам, вырабатывают токсины и вызывают воспаление, что делает слизистую оболочку чувствительнее к воздействию агрессивных факторов; с другой — вырабатывают определённые вещества, из-за чего клетки желудка вырабатывают излишнюю соляную кислоту.</span></p>",
"diagnostics": "<p>Для диагностики язвенной болезни применяют целый ряд исследований:<br />- рентгенография брюшной полости.<br />- фиброэзофагогастродуоденоскопия (ФЭГДС). Эндоскопическое исследование подтверждает наличие язвенного дефекта, уточняет его локализацию, глубину, форму, размеры, позволяет оценить состояние дна и краев язвы, выявить сопутствующие изменения слизистой оболочки. ФЭГДС дает возможность взять биопсию стенки пораженного органа, с последующим гистологическим исследованием полученного материала для исключения злокачественного характера поражения.<br />- рН-метрия - исследование кислотообразующей функции желудка.<br />- анализ кала на скрытую кровь (для диагностики возможного кровотечения).<br />- исследования на инфекцию Helicobacter pylori (дыхательный тест, обнаружение в сыворотке крови антител к Helicobacter pylori, микробиологический посев, взятого при ФЭГДС материала).</p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Важно придерживаться установленного режима дня, по возможности избегать стрессовых ситуаций, не прибегать к курению и употреблению алкогольных напитков, хотя бы на время лечения, соблюдать прописанную доктором диету, придерживаться правильного режима дня. По обыкновению, срок активного курса лечения составляет около двух недель, а потом нужна поддерживающая терапия с обязательным соблюдением правильного питания.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Медикаментозная терапия состоит из таких препаратов:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">антибактериальные препараты - действие направлено на устранение из организма Helicobacter pylori;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">антациды - средства, снижающие секрецию желудочного сока;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">ингибиторы протонной помпы - их действие влияет на химический состав соляной кислоты, нарушает ее структуру;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Н2‑гистаминоблокаторы - снижают агрессию желудочного секрета;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">спазмолитики - симптоматические препараты, которые снимают болевой синдром.</span></p>\r\n</li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хирургическое лечение проводится по показаниям: осложнения язвенной болезни желудка (кровотечение, пенетрация, перфорация), при частых обострениях, при грубых деформациях желудка в результате рубцовых изменений со стенозированием просвета.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При малигнизации (озлокачествлении) язвы необходимо оперативное лечение, объем которого зависит от того, как рано обнаружена опухоль. Чем раньше выявлена малигнизация язвы, тем меньше будет объем оперативного вмешательства. В таком случае операция по удалению язвы может быть проведена эндоскопически, или лапароскопически.</span></p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">В качестве профилактики язвенной болезни желудка следует:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">уделять сну не менее 6 – 8 часов в сутки;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">минимизировать потребление копченого, жирного и жаренного, такая пища раздражает слизистую оболочку;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">следить за здоровьем зубов, чтобы всегда иметь возможность хорошо пережевывать пищу;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">не допускать частых стрессовых ситуаций, так как они приводят к нервному напряжению и вызывают болевые ощущения в желудке;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">не употреблять алкогольные напитки и не курить;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">при болях в желудке пройти необходимые обследования;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">увеличить количество приемов пищи до 6 в день. Пища должна быть измельченной, показаны кисели, каши, приготовленное на пару мясо, омлет, овощи.</span></p>\r\n</li>\r\n</ul>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ведущим симптомом обострения язвы желудка являются боли в подложечной области, которые могут иррадиировать в левую половину грудной клетки и левую лопатку, грудной или поясничный отдел позвоночника. Боли возникают сразу после приема пищи (при язвах кардиального и субкардиального отделов желудка), через полчаса-час после еды (при язвах тела желудка). </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При обострении часто встречаются также отрыжка кислым, тошнота, запоры. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В период обострения часто удается выявить болезненность в эпигастральной области при пальпации, сочетающуюся с умеренной резистентностью мышц передней брюшной стенки. Также может обнаруживаться локальная болезненность в этой же области.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Типичными для ЯБ являются сезонные (весной и осенью) периоды усиления болей и диспепсических симптомов.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В неосложненных случаях протекает обычно с чередованием периодов обострения (продолжительностью от 3-4 до 6-8 недель) и ремиссии (длительностью от нескольких недель до многих лет). </span></p>",
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