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},
"code": "A48.0",
"name": "Газовая гангрена",
"icd_name": "Газовая гангрена",
"gender": 0,
"age_min": 15,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "a48.0_gazovaya_gangrena",
"lead": "осложнение раневого процесса, возникающее при обсеменении раны бактериями рода Clostridium",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Газовая гангрена — это омертвение тканей организма, вызванное инфекцией, обусловленной ростом и размножением в тканях клостридиальной микрофлоры.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Газовая гангрена вызывается бактериями из рода клостридий, которые в норме обитают в кишечнике травоядных домашних животных, откуда попадают в землю, уличную пыль, на одежду и т. д. В отдельных случаях обнаруживаются в фекалиях и на коже здоровых людей. Размножаются только в безкислородной среде, но в присутствии кислорода могут длительное время сохраняться в виде спор.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В 90% случаев возбудителем газовой гангрены является Clostridium perfringens. Обычно газовая гангрена развивается в результате обширных размозженных ран и травматических отрывов конечностей, реже – в результате ранений толстого кишечника и попадания инородных тел. В отдельных случаях причиной возникновения могут стать даже небольшие раны (особенно – загрязненные обрывками одежды или частицами почвы).</span></p>",
"pathogenesis": "",
"diagnostics": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагноз газовая гангрена выставляется на основании клинической картины и подтверждается дополнительными исследованиями. При изучении раневого отделяемого под микроскопом обнаруживаются клостридии. Рентгенологическое обследование подтверждает наличие газа в тканях. </span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение включает в себя неотложное оперативное лечение в сочетании с активной общей терапией. Рану широко вскрывают лампасными разрезами (широкими продольными разрезами на протяжении всего сегмента, включающими в себя разрез кожи, подкожной клетчатки и собственной фасции). Все нежизнеспособные ткани иссекают, рану промывают раствором перекиси водорода. При наличии подозрительных участков на соседних сегментах там также производят лампасные разрезы.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Раны обязательно оставляют открытыми и рыхло дренируют марлей, пропитанной раствором марганцовки или перекиси водорода. В течение первых 2-3 суток перевязки производятся 2-3 раза в день, в дальнейшем – ежедневно. При быстром прогрессировании, вовлечении в процесс всех мягких тканей и омертвении конечности выполняется ампутация или экзартикуляция. Ампутация проводится гильотинным способом, с отсечением всех слоев на одном уровне. Рану оставляют открытой, на культе выполняют лампасные разрезы, раны дренируют, используя марлю, смоченную в растворе перманганата калия или перекиси водорода.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Сразу после постановки диагноза начинают массивную инфузионную терапию с использованием плазмы, альбумина, растворов белков и электролитов. При анемии проводят переливание крови. Антибиотики вводят в высоких дозах внутриартериально или внутривенно. В послеоперационном периоде пациентам назначают гипербарическую оксигенацию. Выполняют внутривенное введение противогангренозной сыворотки. При установленном возбудителе используют моновалентную сыворотку, при неустановленном – поливалентную.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основным средством профилактики газовой гангрены является адекватная своевременная первичная обработка раневой поверхности и назначение антибиотиков широкого спектра действия. В процессе обработки должны быть иссечены все нежизнеспособные ткани, а также дно и края раны. Следует помнить, что антибиотикотерапия обязательна при любых обширных ранах, особенно – обильно загрязненных и сопровождающихся размозжением тканей. Профилактическое использование противогангренозных сывороток недостаточно эффективно и может стать причиной развития анафилактического шока.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пациентов с газовой гангреной изолируют, выделяют им отдельный сестринский пост, перевязочный материал немедленно сжигают, инструменты и белье подвергают специальной обработке. Споры клостридий обладают высокой устойчивостью к кипячению, поэтому инструмент следует обрабатывать в условиях повышенного давления в паровом стерилизаторе либо в сухожаровом шкафу. Любые медицинские мероприятия необходимо проводить в резиновых перчатках, которые по окончании процедуры сжигают или погружают в дезинфицирующий состав (лизол, карболовую кислоту, хлорамин).</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заболевание начинается стремительно, уже на первый-третий день после ранения или травмы развивается отек тканей, в ране продуцируется мутное отделяемое с пузырьками газа и крайне неприятным запахом. Отечность быстро распространяется, на коже появляются пузыри с геморрагическим содержимым внутри, пятна зеленого цвета. Конечность становится холодной, мышцы приобретают вид вареного мяса, их волокна расслаиваются. За 10-12 часов один из видов клостридии способен разрушить подкожную клетчатку до костей.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нарастают симптомы общей интоксикации организма:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Учащенное сердцебиение;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гипертермия до 39-40°;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ломота в мышцах;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Частое дыхание;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Жажда;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Бессонница;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Головная боль;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Повышенная возбудимость или, наоборот, подавленность;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Уменьшение количества выделяемой мочи, далее ее полное отсутствие;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Крепитация (треск) при нажатии на поврежденные ткани.</span></p>\r\n</li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В крови стремительно разрушаются эритроциты, возникает анемия и гемолитическая желтуха.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В своем развитии гангрена проходит 4 стадии:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Стадия ограниченной гангрены. Отек тканей и отделяемое минимальны, рана сухая, имеется боль, кожа бледная.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Стадия распространения. Поражение и некроз тканей продвигаются по конечности, боль приобретает распирающий характер, мышцы обескровлены, кожа желтеет, на ней заметны пятна.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Третья стадия. Боль уменьшается или прекращается совсем, конечность увеличивается, холодеет, пульсация прекращается. Отечность и газы распространяются по большой площади тела, на коже образуются пузыри с бурым содержимым.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Стадия сепсиса. Интоксикация организма значительна, рана наполняется гноем, очаги с гнойным содержимым фиксируются отдаленно от первичного внедрения бактерий.</span></p>\r\n</li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если больной не получает своевременную помощь, через 2-3 дня наступает летальный исход.</span></p>",
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},
"code": "O92.6",
"name": "Галакторея",
"icd_name": "Галакторея",
"gender": 0,
"age_min": 15,
"age_max": 70,
"cause": [
"0"
],
"periodicity": 1,
"slug": "o92.6_galaktoreya",
"lead": "выделение из сосков молозива или молока, не связанное с грудным вскармливанием",
"description": "",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причинами, вызывающими галакторею могут быть:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">опухоль в гипофизе (пролактинома);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">хронические патологии печени или почек;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">гипотиреоз (дисфункция щитовидной железы);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">применение некоторых лекарственных препаратов (например, психотропных средств, гормональных контрацептивов, медикаментов, снижающих давление, наркотических веществ);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">воспалительные процессы в железистой ткани (мастит);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">различные виды мастопатии;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нейрогенные нарушения.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При неустановленной причине (около 50% случаев) диагностируют идиопатическую галакторею.</span></p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">У человека секреция пролактина контролируется сложным нейроэндокринным механизмом, в ней принимают участие центральная и периферическая нервная система. Ингибируют выбросы пролактина дофамин, соматостатин, гамма-аминомасляная кислота, гастрин и некоторые другие пептиды. Стимулирующими факторами являются окситоцин, ТТГ, ГнРГ, меланоцитстимулирующий гормон, серотонин, опиаты, инсулин, эстрогены и андрогены.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основным подавляющим фактором является дофамин. При снижении его влияния происходит увеличение выброса пролактина в кровь. Из-за длительной стимуляции в гипофизе клеток-лактотрофов сначала они гиперплазируются, а затем возникают микро- и макроаденомы. Под его влиянием нарушается синтез гонадотропин-рилизинг гормона, уменьшается выброс ФСГ и ЛГ. У женщины на фоне галактореи изменяется менструальный цикл по типу аменореи, развивается бесплодие.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Экстрагенитальное влияние пролактина приводит к нарушению углеводного обмена, способствует конверсии глюкозы в жиры и развитию ожирения. У многих возникает инсулинорезистентность. Стимулируется продукция дигидроандростендиона, у женщин формируется гиперандрогения с характерными для нее симптомами. Эндокринные нарушения приводят к развитию остеопении.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">С учетом причины заболевания и имеющихся симптомов врач может назначить следующие виды обследования:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Анализ анамнеза жалоб и заболеваний (когда появились основные или дополнительные симптомы галактореи);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">анализ анамнеза жизни;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">результаты осмотра – имеются ли выделение из сосков, их цвет (желтый, зеленый, молочный);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">определение уровня пролактина в крови;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">рентгенография мозга, которая позволяет посмотреть изменение и увеличение костного вместилища гипофиза при опухолях гипофиза;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">компьютерная томография;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">магнитно-резонансная томография мозга – обнаруживает мелкие опухоли;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">определение уровня гормонов щитовидной железы в крови;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">рентгенография легких – выявляет опухоль легких, которая может быть причиной галактореи;</span></li>\r\n<li><span style=\"background-color: transparent; font-size: 7pt; font-family: Verdana; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">консультация врача-эндокринолога.\u2028</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Цель лечения галактореи - нормализация уровня гормонов, восстановление фертильности. Методы лечения многообразны и зависят от причин заболевания. При опухолевых процессах предпочтение отдается хирургическим методам терапии. При галакторее, возникшей вторично на фоне других заболеваний, необходимо лечение основной причины гиперпролактинемии.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Консервативная терапия</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Медикаментозное лечение галактореи направлено на подавление синтеза пролактина, восстановление нормального уровня половых гормонов. Женщины наблюдаются у гинеколога женской консультации, госпитализация в отделение гинекологии или эндокринологии необходима только для инвазивной диагностики. Применяются следующие группы препаратов:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Агонисты дофамина. Действуют на рецепторы дофамина в мозге, подавляют синтез и выбросы пролактина. Предпочтение отдается каберголину, бромокриптин действует неселективно, поэтому имеет большое количество побочных эффектов.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гормоны щитовидной железы. Назначается левотироксин натрия при диагностированном гипотиреозе. В случаях сохранения повышенного пролактина и галакторее на фоне лечения, дополнительно используют агонисты дофамина.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Антиандрогены. Используются при поликистозе, который стал причиной галактореи. Назначают комбинированные оральные контрацептивы с выраженным антиандрогенным действием. В их состав должен входит ципротерон, хлормадинон, диеногест или дросперинон.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Стимуляторы овуляции. После снижения гормона до нормальных показателей и прекращения галактореи должен восстановиться цикл, начинаются менструации. Если овуляция не происходит, используют кломифен цитрат или летрозол для ее стимуляции.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хирургическое лечение</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Оперативное лечение проводится в отделении нейрохирургии. Оно показано при неэффективности медикаментозной терапии или ее непереносимости, повышении внутричерепного давления, признаках сдавления хиазмы. Удаление опухоли требуется при ее прогрессирующем росте, появлении ликвореи. Использовать агонисты дофамина нельзя у пациентов с психическими расстройствами, это вызывает обострение основного заболевания. Макроаденома гипофиза не оперируется.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лучевая терапия</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">При аденоме гипофиза используется лучевая терапия в случаях, когда невозможно проведение хирургического лечения. Если у пациенток нет положительной динамики при медикаментозной терапии, остается только радиационное облучение. Оно сопряжено с опасностью повреждения других клеток системы гипофиза и гипоталамуса. У многих больных через несколько лет развивается гипопитуитаризм.</span></p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика галактореи заключается в своевременном обращении к врачу при любых эндокринных расстройствах, предотвращении черепно-мозговых травм, инфекционных заболеваний. Привести к галакторее могут стрессы, нервные расстройства, поэтому рекомендуется предотвращать появление этих состояний.</span></p>",
"clinical_picture": "<ul>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Выработка грудного молока </span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Прекращение менструации (аменорея)</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нерегулярные менструальные циклы</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Бесплодие</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Снижение либидо (полового влечения)</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эректильная дисфункция</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гирсутизм</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Головные боли</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Слепота (потеря зрения)</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хотя непредвиденная выработка грудного молока может быть единственным симптомом пролактиномы, у многих женщин также прекращаются менструации (аменорея) или менструальные циклы становятся менее частыми. У женщин с пролактиномами часто отмечается низкий уровень эстрогена, что может вызывать вагинальную сухость и в связи с этим чувство дискомфорта при половом акте. \u2028\u2028Приблизительно две трети мужчин с пролактиномами теряют интерес к половой жизни (снижение полового влечения), и у них отмечается эректильная дисфункция. У некоторых женщин также снижается половое влечение и отмечается гирсутизм (чрезмерный рост волос на лице и теле). Высокий уровень пролактина может вызвать бесплодие у мужчин и женщин. \u2028\u2028При наличии пролактиномы большого размера она может давить на нервы головного мозга, расположенные непосредственно над гипофизом, вызывая головные боли или слепоту в определенных полях зрения.</span></p>",
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},
"code": "R02",
"name": "Гангрена",
"icd_name": "Гангрена, не классифицированная в других рубриках",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
"0",
"1"
],
"periodicity": 1,
"slug": "r02_gangrena",
"lead": "некроз тканей живого организма чёрного или очень тёмного цвета, развивающийся в тканях органов, прямо или через анатомические каналы связанных с внешней средой",
"description": "<p>Гангрену классифицируют по консистенции погибшей ткани (сухая, влажная), этиологии (инфекционная, аллергическая, токсическая и др.), патогенезу (молниеносная, газовая, госпитальная).</p>",
"etiology": "<p>Причины, вызывающие гангрену тканей, делятся на три группы:</p>\r\n<ol>\r\n<li>Нарушение кровоснабжения тканей. Такая гангрена называется ишемической. Это наиболее частая причина гангрены в мирное время. Поражение артериальных сосудов при атеросклерозе, диабете и болезни Бюргера часто приводит к гангрене. Бывает и венозная <a title=\"Перейти на страницу симптома Потемнение тканей\" href=\"/symptom/potemnenie_tkaney/\">гангрена</a> при тотальном глубоком венозном тромбозе</li>\r\n<li>Инфекционная гангрена. Чаще всего возникает при глубоких ножевых или огнестрельных ранениях, но иногда после незначительных ссадин у больных диабетом и при пульпите (гангрена пульпы). Вызывается анаэробными бактериями рода Clostridium (газовая <a title=\"Перейти на страницу симптома Потемнение тканей\" href=\"/symptom/potemnenie_tkaney/\">гангрена</a>); кишечными палочками (Escherichia), аэробактериями (энтеробактерии), стрептококками (Streptococcus) и бактериями рода Proteus.</li>\r\n<li>Физические и химические воздействия. В мирное время гангрена может развиваться после обморожений, ожогов III степени. Возможны любые факторы повреждения, вызывающие глубокий некроз тканей.</li>\r\n</ol>",
"pathogenesis": "",
"diagnostics": "<p>Диагноз ставится на основании:</p>\r\n<p>Данных осмотра: гангрена имеет характерный вид. Также во время осмотра определяется пульсация артерий, может ощущаться крепитация подкожных тканей.</p>\r\n<p>В общем анализе крови: значительный уровень воспаления.</p>\r\n<p>В биохимическом анализе крови определяется поражение продуктами распада внутренних органов.</p>\r\n<p>Микробиологический анализ крови: через 5 дней придет ответ, попала ли инфекция в кровь.</p>\r\n<p>Анализ отделяемого из раны на микрофлору: так определяют, чем именно вызвана (или осложнилась) <a title=\"Перейти на страницу симптома Потемнение тканей\" href=\"/symptom/potemnenie_tkaney/\">г</a>ангрена. Так можно отличить газовую гангрену от той, которая осложнилась попаданием в рану бактериальной инфекции.</p>\r\n<p>Дуплексное сканирование сосудов пораженной конечности позволяет понять причину гангрены.</p>\r\n<p>Артериография сосудов – более детальное исследование артерий пораженной конечности.</p>",
"treatment": "<p align=\"justify\">Лечение гангрены проводится в условиях стационара и включает в себя общие и местные мероприятия. При гангрене, возникшей вследствие воздействия химических и механических факторов (размозжение конечности, ожоги, отморожения и т. д.) пациента направляют к травматологам.</p>\r\n<p align=\"justify\">Выбор отделения при других видах гангрены зависит от локализации патологии: лечением гангрены органов брюшной полости (поджелудочной железы, аппендикса, желчного пузыря, кишечника), а также гангрены конечностей при сахарном диабете занимаются хирурги (отделение общей хирургии), лечением гангрены легкого – торакальные хирурги, лечением гангрены, обусловленной сосудистой патологией – сосудистые хирурги.</p>\r\n<p align=\"justify\">Пациенту с гангреной назначают постельный режим. Принимают меры для стимуляции кровообращения и улучшения питания тканей. Чтобы устранить рефлекторный спазм коллатеральных сосудов по показаниям выполняют новокаиновые блокады.</p>\r\n<p align=\"justify\">Проводятся общие лечебные мероприятия по улучшению функции сердечнососудистой системы, борьбе с инфекцией и интоксикацией. Производится внутривенное введение растворов, плазмы и кровезаменителей, при необходимости – переливание крови. Назначаются антибиотики и сердечные препараты.</p>\r\n<p align=\"justify\">При гангрене, развившейся вследствие поражения сосудов, одной из важнейших задач является восстановление кровообращения в еще жизнеспособных тканях. При тромбозах назначают тромболитические препараты. В случае необходимости выполняют оперативные вмешательства на артериях.</p>\r\n<p align=\"justify\">Тактика местного лечения зависит от вида гангрены. При сухой гангрене на начальных этапах проводится консервативная терапия. После формирования демаркационного вала и мумификации некротизированного участка выполняется ампутация или некрэктомия. Уровень ампутации выбирается так, чтобы максимально сохранить функцию конечности и при этом обеспечить благоприятные условия для заживления культи. В ходе оперативного вмешательства дистальная часть культи сразу закрывается кожно-мышечным лоскутом. Заживление происходит первичным натяжением.</p>\r\n<p align=\"justify\">При влажной гангрене показано немедленное иссечение некроза в пределах здоровых тканей. Некрэктомия или ампутация производятся в экстренном порядке. Конечность отсекается гильотинным способом. Формирование культи осуществляется после очищения раны.</p>\r\n<p align=\"justify\">При гангрене внутренних органов проводится экстренное оперативное вмешательство для удаления некротизированного органа.</p>",
"prevention": "<p>Профилактика заболевания заключается в своевременном:</p>\r\n<ul>\r\n<li>обращении пациента при наличии симптомов «перемежающейся хромоты»,</li>\r\n<li>лечении заболеваний артерий (выбор метода — консервативное и/или оперативное лечение остаётся за сосудистым хирургом),</li>\r\n<li>диагностике поражения артерий нижних конечностей (ультразвуковое дуплексное ангиосканирование артерий нижних конечностей, ангиография артерий нижних конечностей).</li>\r\n</ul>\r\n<p> </p>",
"clinical_picture": "<p>Специфическим симптомом нарушения кровоснабжения нижних конечностей является боль в мышцах нижних конечностей, которая возникает при ходьбе и исчезает после непродолжительного отдыха. Чаще всего, эта боль сосредотачивается в икроножных мышцах. С течением времени расстояние безболевой ходьбы сокращается, кожа нижних конечностей становится прохладной, может приобретать бледную или синюшно-багровую окраску, процессы заживления незначительных ран на ногах также замедляются.</p>\r\n<p>На коже пальцев, стопы, голени появляются некрозы, почернения вследствие омертвения тканей и трофические язвочки — раны не заживают и часто инфицируются. Но даже на этой стадии заболевания восстановление кровотока предупреждает развитие гангрены.</p>\r\n<p> </p>",
"image": "http://api.symptomd.ru/storage/806049cca6b26f04a49f514dff9c0099_kYFekgc.png",
"image_alt": "Газовая гангрена",
"standard_type": 2,
"danger": 75,
"published": 1,
"parent": null,
"block_rubric": 187,
"standards": []
},
{
"id": 6667,
"symptoms": [
{
"id": 2608,
"synonyms": [
{
"name": "рвота"
},
{
"name": "тошнота"
}
],
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}
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"description": "Гастрит — воспаление слизистой оболочки желудка, дуоденит -воспаление слизистой оболочки двенадцатиперстной кишки. С точки зрения клиницистов, различают хронические и острые воспалительные процессы. ",
"etiology": "<p>Причиной развития гастрита чаще всего является бактерия хеликобактер пилори, которая поражает слизистую оболочку желудка. Также хронический гастрит может возникать на фоне воспалительного заболевания — болезни Крона, характеризующегося воспалением пищеварительного тракта. Длительное употребление алкоголя, аспирина или НПВС также может привести к возникновению хронического гастрита.<br><br>Одна из форм гастрита, известная под названием атрофического или аутоиммунного гастрита, является следствием патологической реакции иммунной системы (вырабатываются антитела, разрушающие ткани слизистой оболочки желудка).<br></p>",
"pathogenesis": "<p>В настоящее время используют так называемую «сиднейскую» классификацию воспалений желудка и двенадцатиперстной кишки, согласно которой при классификации указывают локализацию (гастрит антральный, фукдальный, пангастрит) и описание морфологической картины (гастрит атрофический, эрозивный, рефлюкс-гастрит, гипертрофический).<br>Хотя состояние кислотообразующей функции не отражается в классификации, но ее следует учитывать для подбора адекватного лечения.<br>В зависимости от уровня кислотности выделяют состояния:<br>• анацидные;<br>• гипацидные;<br>• гиперацидные;<br>• с нормальной кислотностью желудочного сока.</p><p><br></p>",
"diagnostics": "<p>Диагностика основана на четком сборе анамнеза (т.е. расспросе больного), выяснении причины заболевания, а также инструментальном исследовании (фибро-гастроскопии, зондировании) для выявления изменений в слизистой оболочке желудка и двенадцатиперстной кишки, УЗИ, лабораторных исследованиях. Данные рентгенологических исследований в этих случаях менее информативны.<br></p>",
"treatment": "<p>Постельный режим, соблюдение диеты, промывание желудка. Медикаментозное лечение: прием адсорбентов, обволакивающих средств, холиноблокаторов периферического действия и спазмолитиков (для уменьшения тошноты и рвоты), оральная регидратация при обезвоживании, при аллергических реакциях – прием антигистаминных препаратов, в случаях инфекции назначается антибиотикотерапия.</p>",
"prevention": "Основные меры предупреждения болезни заключаются в следующем:<br><br> Лечение любых болезней желудочно-кишечного тракта и внутренних органов, недопущение их хронизации.<br> Прекращение курения, полный отказ или ограничение принятия спиртного.<br> Здоровое, полноценное питание.<br> Санация очагов хронической инфекции.<br> Коррекция аллергических заболеваний.<br> Улучшение условий труда, особенно – на вредных производствах, смена работы.<br> Полноценный сон, борьба со стрессами.<br> Регулярное обследование у гастроэнтеролога (при склонности к гастритам), по мере необходимости – противорецидивное лечение.<br><br>",
"clinical_picture": "<p>Клиника развивается через несколько часов после воздействия патологического агента. Наблюдаются диспепсический синдром (\"></a>, \">Рвота</a>\">\">рвота</a></a>, , , неприятный привкус во рту, схваткообразная боль в эпигастральной области), диарейный синдром (жидкий стул 1–2 раза в сутки). Кожа бледная, тургор снижен, язык обложен, отмечается болезненность при пальпации живота в эпигастральной области. </p>",
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},
"code": "K29.7",
"name": "Гастрит неуточненный",
"icd_name": "Гастрит неуточненный",
"gender": 0,
"age_min": 10,
"age_max": 100,
"cause": [
"0",
"3"
],
"periodicity": 1,
"slug": "k29.7_gastrit_neutochnennyy",
"lead": "воспаление слизистой оболочки желудка",
"description": "<p>Гастрит - это <span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">воспаление слизистой оболочки желудка, приводящее к нарушению его функции, в особенности секреторной. При наличии у человека гастрита, поступающая пища плохо перерабатывается, что приводит к нарушению всасываемости полезных веществ для организма человека.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Внешние факторы: </span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">заражение организма бактерией Хеликобактер пилори;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">неправильное питание, избыток в рационе фастфуда и полуфабрикатов;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">курение и злоупотребление алкоголем;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">работа на вредном производстве и проживание в экологически неблагоприятном районе;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">продолжительный прием некоторых медикаментозных средств, например, нестероидных противовоспалительных препаратов;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">продолжительные и регулярные стрессы.</span></p>\r\n</li>\r\n</ul>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Внутренние факторы: </span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">инфекционные заболевания;</span></li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">сбои в функционировании гормональной системы;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">малокровие;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">недостаточная функция почек, легких или сердца;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нарушение метаболизма;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">генетическая предрасположенность;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">воспалительные процессы в брюшном отделе.</span></p>\r\n</li>\r\n</ul>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В основе патогенеза лежит воспаление слизистой оболочки, приводящее к её структурной перестройке. При наличии предрасполагающих факторов и воздействии внешних или внутренних причин запускается процесс длительно текущего воспаления.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В основе хронического воспаления лежит круглоклеточная воспалительная инфильтрация нейтрофилами (видами лейкоцитов крови) и другими клетками иммунной системы слизистой желудка. В результате длительно текущей воспалительной реакции запускаются процессы перестройкой структуры слизистой оболочки желудка и развития в ней дисрегенераторных процессов (нарушенной регенерации) с последующим переходом в дистрофию и атрофию. Это в конечном итоге приводит к нарушению функции желудка, проявляющейся гипо- или ахлоргидрией (снижением или отсутствием соляной кислоты в желудочном соке) и желудочной ахилией.</span></p>",
"diagnostics": "<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Общий клинический анализ крови, мочи</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Анализ кала на копрограмму</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Биохимический анализ крови (печеночные пробы, холестерин, щелочная фосфатаза)</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">ЭКГ</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгенография органов грудной клетки в 2-х проекциях</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгенография пищевода, желудка с бариевой смесью</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">УЗИ гепатобилиарной системы</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Суточное мониторирование рН в нижней части пищевода и желудка</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">ЭГДС</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Неинвазивные тесты для определения Helicobacter pylori</span></p>\r\n</li>\r\n</ul>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основное лечение при гастрите состоит из соблюдения здорового образа жизни и правильного рационального питания.</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отказ от употребления алкогольных, сильногазированных напитков</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Снижение массы тела при ожирении</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отказ от курения</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Исключение приема пищи в больших количествах и в поздние часы</span></p>\r\n</li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Медикаментозное лечение: </span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Прокенетики (способствуют ускорению продвижения пищевого комка от пищевода в желудок, в дальнейшем в двенадцатиперстную кишку, повышение тонуса нижнего пищеводного сфинктера) - Домперидон (Мотилак, Мотилиум), Итоприд (Ганатон)</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Антисекреторные препараты (способствуют подавлению секреции соляной кислоты) - ингибиторы протонной помпы (Омепразол, Пантопразол, Эзомепразол, Рабепразол)</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Антациды (Фосфолюгель, Альмагель, Гевискон)</span></p>\r\n</li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При обнаруженной контаминации слизистой оболочки желудка H.pylory применяется схема лечения с антибактериальными препаратами.</span></p>",
"prevention": "<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отказ от курения и злоупотребления алкоголя.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Соблюдение режима труда и отдыха.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Соблюдение диеты.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Повторные курсы уничтожения Helicobacter pylori (при необходимости).</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактические осмотры врача и диспансеризация.</span></p>\r\n</li>\r\n</ul>",
"clinical_picture": "<p><span id=\"docs-internal-guid-b4aa32eb-7fff-4b8c-0f53-2255a9d38384\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Первые клинические симптомы появляются через 6-12 часов после воздействия патогенного фактора: потеря аппетита, ощущение неприятного вкуса во рту, слюнотечение, тошнота, отрыжка воздухом и пищей, рвота содержимым желудка с примесью слизи и желчи; рвотные массы обильные, имеют неприятный запах. Иногда рвота повторяется, усиливается слабость, появляются головокружение и головная боль. </span></span></p>\r\n<p><span id=\"docs-internal-guid-b4aa32eb-7fff-4b8c-0f53-2255a9d38384\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Отмечается урчание, вздутие живота, понос повторяется многократно, слабость прогрессирует, нарастает обезвоживание, а температура достигает 39 градусов и выше. </span></span></p>\r\n<p><span id=\"docs-internal-guid-b4aa32eb-7fff-4b8c-0f53-2255a9d38384\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">При осмотре больной бледен, кожа сухая, язык обложен серо-жёлтым налетом, ощущается неприятный запах изо рта, живот вздут, пальпация живота чувствительна, давление в эпигастральной области может усиливать тошноту. </span></span></p>\r\n<p><span id=\"docs-internal-guid-b4aa32eb-7fff-4b8c-0f53-2255a9d38384\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Количество мочи, особенно в тяжелых случаях, уменьшено, появляется альбуминурия. </span></span></p>\r\n<p><span id=\"docs-internal-guid-b4aa32eb-7fff-4b8c-0f53-2255a9d38384\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">В анализе крови может отмечаться умеренный нейтрофильный лейкоцитоз. </span></span></p>",
"image": null,
"image_alt": null,
"standard_type": 0,
"danger": 1,
"published": 2,
"parent": 6667,
"block_rubric": 111,
"standards": []
},
{
"id": 11673,
"symptoms": [
{
"id": 2851,
"synonyms": [
{
"name": "упадок сил"
},
{
"name": "мышечная слабость"
},
{
"name": "бессилие"
},
{
"name": "Адинамия"
}
],
"body_points": [
{
"x": 607,
"y": 3819,
"r": 0
}
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"lead": "сочетанное воспаление слизистой оболочки желудка (чаще его привратникового отдела) и 12-перстной кишки, характеризующееся нарушением секреции и моторики желудочно-кишечного тракта",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гастродуоденит – это воспалительное заболевание слизистой оболочки пилорической (привратниковой) зоны желудка и его непосредственного продолжения – двенадцатиперстной кишки, с которой желудок сообщается через сфинктер-привратник. Из-за воспалительного процесса нарушаются процессы пищеварения (нормальная моторика кишечника и выработка желудочного сока), что сказывается на переваривании пищи в целом. </span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Выделяют эндогенные и экзогенные причины развития гастродуоденита. При повышенном кислотообразовании и малой продукции слизи, нарушении гормональной регуляции секреции развивается эндогенный гастродуоденит. Также вызвать развитие гастродуоденита могут заболевания печени и желчных путей, сбои в работе эндокринной системы.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К экзогенным факторам развития относят физические – например, употребление острой, холодной или горячей пищи, воздействие химических препаратов (пестицидов). Немаловажное значение имеет и проникновение в пищеварительный тракт бактерии Helicobacter pylori.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К основным причинам гастродуоденита можно отнести:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Скудное или же очень жирное и острое питание;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Несоблюдение режима приема пищи, еда всухомятку;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Различные стрессы, психологическое давление;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заражение Helicobacter pylori;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инфекции, которые развивались в полости рта и глотке;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В последнее время подмечено, что причинами поверхностного гастродуоденита может быть генетическая предрасположенность к таким заболеваниям.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кроме того, различают острую и хроническую формы гастродуоденита, когда периоды ремиссии чередуются с обострениями.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причины развития острой формы гастродуоденита:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Токсическое воздействие химических веществ и испорченной пищи, раздражающее слизистую желудка и кишечника;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Употребление острых специй и приправ;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Высокая концентрация остаточных пестицидов в продуктах питания;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Осложнения кишечных инфекций и хронических соматических заболеваний;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Повышенное продуцирование в желудке соляной кислоты в сочетании со снижением защитных свойств слизистой оболочки, протекающее на фоне стресса и нарушения режима питания.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагностировать гастродуоденит может врач-гастроэнтеролог, проведя осмотр или необходимые исследования: эзофагогастродуоденоскопию, в случае необходимости – с биопсией слизистой оболочки желудка.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Также необходимо провести исследование желудочной секреции – рН-метрию желудка и двенадцатиперстной кишки. По результатам этих анализов можно определить, какую форму имеет гастродуоденит – с повышенной или пониженной кислотностью, и, соответственно, назначить верное лечение.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Методы диагностирования гастродуоденита:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Фиброэзофагогастродуоденоскопия (ФЭГДС) – точный и информативный метод эндоскопического исследования желудка и 12-перстной кишки при помощи эндоскопа, позволяет оценить тяжесть и характер повреждений, форму гастродуоденита.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Морфологическое исследование тканей слизистой, взятых во время проведения ФЭГДС – осуществляется при помощи микроскопа на клеточном уровне, позволяет диагностировать форму и особенности заболевания.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгеновское исследование с контрастным веществом желудка и 12-перстной кишки – метод менее информативен, чем ФЭГДС, применяется редко.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Интрагастральная pH-метрия – измерение кислотности желудочного сока при помощи электродов, введенных в желудок, помогает определить схему лечения.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Бичастотная интрагастральная импедансометрия – измерение активности желез, продуцирующих соляную кислоту, точно определяет кислотность желудочного сока.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">УЗИ желудка и кишечника – малоинформативный метод, позволяющий определить косвенные признаки гастродуоденита.</span></li>\r\n</ul>\r\n<p> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение тяжелого гастродуоденита должно осуществляться в отделении гастроэнтерологии. При развитии острого состояния для полного излечения достаточно одного курса терапии и соблюдения строгой диеты. Жалобы на неоднократные эпизоды заболевания требуют повторной консультации гастроэнтеролога и проведения полноценного лечения.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пациенту с гастродуоденитом обязательно назначается лечебная диета. В периоды обострения требуется соблюдение особых правил: пища должна быть механически, химически и термически щадящей. Нельзя употреблять острые, копченые и экстрактивные вещества. В период ремиссии специальная диета не требуется, достаточно здорового рационального питания. Для предупреждения рецидивов рекомендуется навсегда отказаться от курения, алкоголя, газированных напитков, крепкого кофе.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лекарственная терапия гастродуоденита зависит от клинической формы заболевания. При повышенной кислотности желудка назначаются антацидные препараты, ингибиторы протонной помпы; при пониженной – ферментные препараты и натуральный желудочный сок. Обнаружение хеликобактерной инфекции требует обязательного назначения антибактериальных препаратов, которые в сочетании с препаратами висмута и ингибиторами протонной помпы позволяют добиться практически полной эрадикации возбудителя. Также комплексная терапия должна включать в себя спазмолитики, репаративные препараты, фитотерапию. В периоде ремиссии рекомендуется санаторно-курортное лечение, употребление минеральных вод.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Главной проблемой в ведении гастродуоденитов является то, что многие пациенты пытаются лечиться самостоятельно, нерационально используя симптоматические средства, бросая начатую терапию при ослаблении симптомов заболевания, не добившись полного излечения. Правильное и своевременное лечение хронического гастродуоденита является лучшей профилактикой язвенной болезни. Даже после достижения стойкой ремиссии требуется постоянное соблюдение принципов рационального питания, здорового образа жизни для предупреждения рецидивов.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика гастродуоденита во многом перекликается с основными принципами лечения. Для предупреждения заболевания необходимо вести здоровый образ жизни, отказаться от таких вредных привычек, как курение и прием спиртного, употребления большого количества крепкого кофе. Необходимо правильно питаться – включать в рацион больше свежих овощей и фруктов, каш, нежирного мяса и рыбы. Следует отказаться от газированных напитков, острой и пряной пищи, жареных блюд. </span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К неспецифическим симптомам, связанным с общим ухудшением самочувствия, относятся слабость, вялость, головная боль, раздражительность, расстройство сна. На этом фоне могут манифестировать кардиалгия, аритмия, гипотония.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Поступающие в организм питательные вещества плохо усваиваются, поэтому больной «беспричинно» худеет. Признаки нарушенного всасывания витаминов и микроэлементов проявляются следующим образом: </span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нарушено усвоение жиров: стеаторея (обильный кашицеобразный зловонный стул светлого цвета);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нарушено усвоение белков: сухие волосы, выпадение волос, отеки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нарушено усвоение углеводов: метеоризм (с которым связан дискомфорт в животе), обильная диарея;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">дефицит витаминов и полезных микроэлементов: ухудшается состояние кожи и ногтей, снижается иммунитет.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Симптомы гастродуоденита могут появиться внезапно, через некоторое время после приема пищи. В некоторых случаях приступ может обостриться натощак.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Боль при гастродуодените носит ноющий или схваткообразный характер, ощущается в верхней средней части живота, может иррадиировать в область пупка или подреберья. В отличие от язвенной болезни, боль носит эпизодический характер, отсутствует сезонность ее возникновения, она менее интенсивная.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Чувство распирания и давления в области живота может быть связано с ферментной недостаточностью. Пациенты жалуются на неприятный горьковатый или кислый привкус во рту, не связанный с приемом пищи, сниженный аппетит.</span></p>",
"image": null,
"image_alt": null,
"standard_type": 0,
"danger": 36,
"published": 1,
"parent": 6667,
"block_rubric": 111,
"standards": []
}
]
}
