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"code": "A58",
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"description": "<p><span id=\"docs-internal-guid-b60682b0-7fff-cdbd-f559-1ede3db56f0d\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Паховая гранулема – медленно прогрессирующее инфекционное венерическое заболевание, характеризующееся обширными изъязвлениями кожи и поражением лимфатических узлов генитальной и перианальной области.</span></span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Возбудитель венерической гранулемы – Calymmatobacterium granulomatis, также его называют тельцами Донована.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заразиться этим заболеванием можно не только половым путем, но и бытовым. Инфекция может проникнуть через микродефекты на коже и слизистых. Микроорганизмы, которые приводят к развитию донованоза, обладают повышенной устойчивостью к воздействию окружающей среды и могут выживать вне человеческого организма. Распространению инфекции благоприятствуют влажный климат и жара.</span></p>",
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"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагноз устанавливается после проведения комплекса лабораторных исследований:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">исследование полученной из язвы серозной жидкости на бледную трепонему в темном поле микроскопа;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">исследование мазков отделяемого из язв (окрашенных по Граму препаратов) на стрептобациллы Дюкрея;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">исследование возбудителя в окрашенных по Лейшману или Романовскому-Гимзе мазках, приготовленных путем раздавливания кусочков ткани краев язв между двумя предметными стеклами.</span></li>\r\n</ul>\r\n<p> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Назначают один из следующих антибиотиков: стрептомицин, тетрациклин, эритромицин, хлорамфеникол или ко-тримоксазол. В течение 6 месяцев после лечения пациент должен наблюдаться у врача, чтобы удостовериться, что заболевание вылечено.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если паховая гранулема оставлена без лечения, инфекция может распространяться на кости, суставы или печень; вызывать значительное снижение веса, повышение температуры тела и анемию.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Защитить себя от заболеваний, передающихся половым путем, можно при соблюдении простых правил безопасности:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Старайтесь избегать многочисленных и случайных сексуальных связей.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Обязательно пользуйтесь презервативом при сексуальных отношениях с малознакомым человеком или с тем, кто имеет нескольких половых партнеров.</span></p>\r\n</li>\r\n</ul>",
"clinical_picture": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Симптомы заболевания появляются приблизительно через 1-12 недель после инфицирования. Первый симптом – появление безболезненного красного узелка, который медленно превращается в круглое приподнятое образование. Инфекция поражает половой член, мошонку, пах и бедра у мужчин, и вульву, влагалище и окружающую кожу – у женщин. Как у мужчин, так и у женщин могут быть инфицированы задний проход, ягодицы и лицо. Приподнимающиеся над кожей узелки постепенно покрывают половые органы. Заживление медленное, с формированием рубцовой ткани. Обычно узелки инфицируются другими микроорганизмами.</span></p>",
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