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},
"code": "E05",
"name": "Гипертиреоз",
"icd_name": "Тиреотоксикоз [гипертиреоз]",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
0,
1
],
"periodicity": 4,
"slug": "e05_gipertireoz",
"lead": "клинический синдром, обусловленный повышением уровня тиреоидных гормонов в крови и их токсическим действием на различные органы и ткани",
"description": "",
"etiology": "<p>Причины развития тиреотоксикоза:</p>\r\n<ul>\r\n<li>высокая функция тиреоцитов (образование избытка гормонов);</li>\r\n<li>секреция гормонов вне ткани щитовидной железы;</li>\r\n<li>разрушение ткани железы (временное повышение гормонов в крови);</li>\r\n<li>введение синтетических гормонов.</li>\r\n</ul>\r\n<p>Высокая функция тиреоцитов чаще всего наблюдается при первичном тиреотоксикозе. Может быть повреждена вся ткань щитовидной железы или ее локальные участки (токсические узлы). Наиболее часто эту форму тиреотоксикоза вызывает диффузный токсический зоб (Базедова болезнь, болезнь Грейвса), многоузловой и смешанный зоб, токсическая аденома, передозировка йода.</p>\r\n<p>Секреция тиреоидных гормонов вне тиреоидных тканей возможна в яичниках и в активно функционирующих метастазах рака щитовидной железы.</p>\r\n<p>Разрушение тиреоцитов приводит к резкому выделению в кровь коллоида, богатого гормонами. Такая ситуация возникает при:</p>\r\n<ul>\r\n<li>подостром тиреоидите;</li>\r\n<li>безболевом тиреоидите;</li>\r\n<li>послеродовом тиреоидите;</li>\r\n<li>йодиндуцированном тиреоидите типа 2.</li>\r\n</ul>\r\n<p>Тиреотоксикоз носит транзиторный характер. Проходит без лечения. Из-за деструкции клеток щитовидной железы со временем может формироваться гипотиреоз.</p>\r\n<p>Медикаментозный тиреотоксикоз – это либо ошибочное назначение избыточных доз синтетического тироксина, либо самолечение. Иногда пациенты принимают гормоны с целью симуляции эндокринного заболевания.</p>",
"pathogenesis": "<p>Тиреоидине гормоны увеличивают потребление кислорода тканями, повышая образование тепла и энергетический обмен <br />Повышается чувствительность тканей к катехоламинам и симпатической стимуляции <br />Увеличивается превращение андрогенов в эстрогены в тканях и возрастает содержание циркулирующего глобулина, связывающего половые гормоны, что повышает соотношение эстрогенов к андрогенам. Эти гормональные изменения могут вызвать гинекомастию у мужчин <br />Быстрое разрушение кортизола под влиянием тиреоидных гормонов обусловливает клиническую картину гипокортицизма (обратимая надпочечниковая недостаточность). </p>",
"diagnostics": "<p>Диагностика такого состояния, как тиреотоксикоз, требует тщательного анализа и сопоставления жалоб пациента, данных клинического осмотра больно в кабинете у врача-эндокринолога, а также результатов инструментальных и лабораторных обследований, выполненных по направлению доктора.</p>\r\n<p>Для установления самого факта высокого уровня тироксина, тиронина и тиреотропного гормона проводят исследование крови, а для уточнения характера поражения и выявления возможной причины развития тиреотоксикоза определяют уровень антител к клеткам щитовидной железы, некоторым вирусам и бактериям.</p>\r\n<p>Для уточнения размеров и особенностей строения органа, выявления характера патологического процесса в щитовидной железе обязательно проводят ультразвуковое исследование щитовидной железы и органов шеи. Если результатов этого исследования оказывается недостаточно, то выполняется сканирование щитовидной железы с радиоактивными изотопами (йодом или технецием), а также сцинтиграфическое исследование этого органа эндокринной системы. При необходимости результаты диагностики дополняют сведениями, полученными после компьютерной и магниторезонансной томографии.</p>\r\n<p>Если у пациента обнаруживается <a href=\"/symptom/ekzoftalm/\" title=\"Перейти на страницу симптома Экзофтальм\">экзофтальм</a>, то для уточнения его характера необходима консультация квалифицированного офтальмолога с обязательным УЗИ области глазниц (изучается состояние клетчатки, расположенной внутри глазницы за глазным яблоком). При выявлении неврологических или психологических жалоб может понадобиться консультация невропатолога, нейрохирурга или психиатра (психоневролога). При обнаружении симптомов расстройств репродуктивной системы необходим осмотр гинеколога или уролога-андролога.</p>\r\n<p>Только после проведения всех этих исследований и консультаций можно установить, какое именно заболевание или состояние спровоцировало развитие тиреотоксикоза – от этого напрямую зависит возможность лечения этого синдрома.</p>",
"treatment": "<p> </p>\r\n<p>Перед началом лечения тиреотоксикоза необходимо определить причину, вызвавшую данное заболевание.</p>\r\n<p>Самой распространенной причиной тиреотоксикоза является болезнь Грейвса. Сегодня есть три вида терапии данного недуга: медикаментозное лечение (тиреостатические препараты – Пропицил, Мерказолил, Тирозол, Метизол и проч.), терапия радиоактивным йодом и хирургическое вмешательство.</p>\r\n<p>Если заболевание вызвано деструктивными процессами в щитовидной железе, то лечение тиреотоксикоза будет заключаться в применении глюкокортикостероидных гормонов (преднизолон). Длительность терапии и дозировка подбираются индивидуально.</p>\r\n<p>Что касается оперативного лечения при тиреотоксикозе, то оно может быть выполнено только после лечения тиреостатиками.</p>\r\n<p>Если говорить о народных методах, то они, как правило, приводят к серьезным осложнениям (особенно со стороны сердечнососудистой системы). Поэтому перед тем, как прибегнуть к нетрадиционному лечению тиреотоксикоза, необходимо обязательно проконсультироваться со своим лечащим доктором, так как результаты самолечения могут быть самыми непредсказуемыми.</p>",
"prevention": "<p><br data-mce-bogus=\"1\"></p>",
"clinical_picture": "<p>Если вы чувствуете себя в последнее время раздражительным, эмоциональным, замечаете частую смену настроения, плаксивость, усиленное потоотделение, чувство жара, <a href=\"/symptom/narushenie_serdechnogo_ritma/\" title=\"Перейти на страницу симптома Нарушение сердечного ритма\">сердцебиение</a>, ощущение перебоев в работе сердца, похудели - это повод обратиться к врачу и сдать анализы на гормоны щитовидной железы.</p>\r\n<p>Cимптомы тиреотоксикоза.</p>\r\n<ul>\r\n<li>изменения метаболизма</li>\r\n<li>наблюдают повышение основного обмена и снижение веса, несмотря на хороший аппетит и достаточный приём пищи</li>\r\n<li><a href=\"/symptom/potlivost/\" title=\"Перейти на страницу симптома потливость\">потливость</a> и непереносимость тепла отражают наличие повышенного теплообразования</li>\r\n<li>нередко — обратимая гипергликемия</li>\r\n<li>увеличение щитовидной железы</li>\r\n<li>сердечно-сосудистые эффекты:\r\n<ul>\r\n<li>ЧСС увеличивается; возникает стойкая синусовая <a href=\"/symptom/tahikardiya/\" title=\"Перейти на страницу симптома Тахикардия\">тахикардия</a> с частотой 120 в мин и более (не исчезающая во время сна и плохо поддающаяся лечению сердечными гликозидами) — больной ощущает сердцебиения в области шеи, головы и живота</li>\r\n<li>другие аритмии вследствие увеличения возбудимости миокарда, например, мерцание и трепетание предсердий</li>\r\n<li>тенденция к повышению систолического АД и снижению диастолического АД (большое пульсовое давление)</li>\r\n<li>симптомы хронической сердечной недостаточности.</li>\r\n</ul>\r\n</li>\r\n<li>симптомы со стороны ЖКТ\r\n<ul>\r\n<li>повышенный аппетит</li>\r\n<li>запоры или диарея</li>\r\n<li>приступы болей в животе</li>\r\n<li>возможна рвота</li>\r\n<li>в тяжёлых случаях — обратимое поражение печени (увеличение размеров, болезненность, возможна <a href=\"/symptom/zheltuha/\" title=\"Перейти на страницу симптома Желтуха\">желтуха</a>)</li>\r\n</ul>\r\n</li>\r\n<li>изменения кожи и волос. Кожа тёплая и влажная вследствие вазодилатации периферических сосудов и повышенного потоотделения. Характерны тонкие, шелковистые волосы, возможна ранняя седина.</li>\r\n<li>воздействие на ЦНС. <a href=\"/symptom/trevozhnost/\" title=\"Перейти на страницу симптома Тревожность \">Беспокойство</a>, <a href=\"/symptom/razdrazhitelnost_i_ozloblenie/\" title=\"Перейти на страницу симптома Раздражительность и озлобление\">раздражительность</a>, патологическая отвлекаемость, лёгкие нарушения памяти, <a href=\"/symptom/drozhanie/\" title=\"Перейти на страницу симптома Дрожание \">тремор</a>. Психические проявления гипертиреоза могут быть настолько выраженными, что напоминают клиническую картину тревожного расстройства, реже — мании или депрессии[2]:276.</li>\r\n<li>расстройства половой сферы:\r\n<ul>\r\n<li>у женщин — <a href=\"/symptom/narushenie_menstrualnogo_cikla/\" title=\"Перейти на страницу симптома Нарушение менструального цикла\">нарушение менструального цикла</a> (вплоть до аменореи)</li>\r\n<li>у мужчин — снижение потенции, возможна гинекомастия.</li>\r\n</ul>\r\n</li>\r\n<li>мышечная <a href=\"/symptom/slabost/\" title=\"Перейти на страницу симптома Слабость\">слабость</a> и <a href=\"/symptom/utomlyaemost/\" title=\"Перейти на страницу симптома Утомляемость\">утомляемость</a> (вследствие сопутствующего гипокортицизма).</li>\r\n</ul>",
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"code": "E11",
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"lead": "хроническое заболевание, вызванное абсолютным дефицитом инсулина вследствие недостаточной его выработки поджелудочной железой, приводящее к стойкой гипергликемии и развитию осложнений",
"description": "Диабет 2 типа составляет 85—90 % от всех типов сахарного диабета и наиболее часто развивается у людей старше 40 лет, и, как правило, ассоциирован с ожирением. Заболевание прогрессирует медленно. Для него характерны второстепенные симптомы, кетоацидоз развивается редко. С течением времени развиваются осложнения: микро- и макроангиопатия, нефро- и нейропатия, ретинопатия и другие",
"etiology": "<p>Генетический фактор – имеет полигенный тип наследования, обусловленный множественными генетическими дефектами, вызывающими диабет или предрасположенность к нему. Возможная причина – изменение уровня экспрессии генов, контролирующих секрецию инсулина и его действие на ткани – мишени. Для развития диабета требуется воздействие внешних факторов: возраст после 40 лет, <a href=\"/symptom/ozhirenie/\" title=\"Перейти на страницу симптома Ожирение\">ожирение</a>, употребление высококалорийной пищи с легко усвояемыми углеводами, переедание, <a href=\"/symptom/trevozhnost/\" title=\"Перейти на страницу симптома <a href=\"/symptom/trevozhnost/\" title=\"Перейти на страницу симптома Тревожность \">Тревожность</a> \">стресс</a>, смена образа жизни.</p>\r\n<p> </p>\r\n<p>Группа абсолютного риска: однояйцовый близнец, партнер которого болен сахарным диабетом (достигает 100 % в течение всей жизни); дети, у которых оба родителя больны сахарным диабетом; дети, у которых один из родителей болен сахарным диабетом, а по линии другого больны родственники; матери, родившие мертвого ребенка, у которого обнаружена гиперплазия островковой ткани поджелудочной железы.</p>\r\n<p> </p>\r\n<p>Группа относительного риска: страдающие ожирением, распространенным атеросклерозом, гипертонической болезнью, хроническим панкреатитом, почечным диабетом, женщины с отягощенным акушерским анамнезом.</p>",
"pathogenesis": "<p>В поджелудочной железе нарушается секреция инсулина в виде качественных, кинетических, количественных изменений (снижение количества и дисфункции β-клеток).</p>\r\n<p> </p>\r\n<p>В периферических тканях, которые резистентны к инсулину (печень, жировая и мышечная ткань), происходит нарушение транспорта и метаболизма глюкозы.</p>\r\n<p> </p>\r\n<p>В печени повышается продукция глюкозы вследствие глюконеогенеза в связи с дефицитом инсулина и избытка глюкагона. Наблюдается нарушение чувствительности печени к инсулину, повышение свободных жирных кислот и лактата, отсутствие снижения продукции глюкозы печенью в связи с сокращением ранней фазы секреции инсулина и недостаточным снижением секреции глюкагона, отсутствие снижения продукции глюкозы ночью.</p>",
"diagnostics": "<p>На основании клиники (симптомов диабета), лабораторных данных (уровень глюкозы в плазме натощак > 7,0 ммоль/л не менее чем в двух исследованиях в разные дни, уровень глюкозы в плазме или капиллярной крови через 2 ч после приема глюкозы в дозе 75 г (детям 1,75 г/кг массы тела, но не больше 75 г), 7,8–11,1 ммоль/л. В норме уровень глюкозы в крови составляет 3,3–5,5 г/л).</p>",
"treatment": "<p>Диетотерапия – ограничение или устранение из диеты легкоусвояемых углеводов (сладостей, меда, шоколада), обеспечение организма физиологическими количествами белков, жиров, углеводов, витаминов. Рекомендуются продукты, богатые клетчаткой, при артериальной гипертонии ограничить употребление соли.</p>\r\n<p> </p>\r\n<p>Суточный калораж рассчитывается с учетом должной массы тела. При компенсированном сахарном диабете 60 % суточного калоража должно покрываться углеводами, 24 % – жирами, 16 % – белками. Режим распределения суточного калоража: завтрак – 25 % суточной калорийности, второй завтрак – 10–15 % суточной калорийности, обед – 25–30 % суточной калорийности, полдник – 5–10 % суточной калорийности, ужин – 20–25 % суточной калорийности, второй ужин – 5–10 % суточной калорийности.</p>\r\n<p> </p>\r\n<p>1 хлебная единица = 12 г углеводов = 48–50 ккал.</p>\r\n<p> </p>\r\n<p>Физические нагрузки должны быть индивидуальными с учетом возраста больного, рекомендуются регулярные прогулки по 30 мин вместо езды на машине, подъем по лестнице, плавание по 1 ч 3 раза в неделю. Однако нужно помнить, что интенсивные физические нагрузки вызывают острое гипогликемическое состояние. При гликемии выше 13–15 ммоль/л физические нагрузки не рекомендуются.</p>\r\n<p> </p>\r\n<p>Пероральные сахароснижающие препараты: препараты сульфонилмочевины, бигуаниды, тиазолидиндионы, меглитиниды и производные фенилаланина, ингибиторы L-глюкозидазы.</p>\r\n<p> </p>\r\n<p>Инсулинотерапия назначается при неэффективности диеты и пероральных сахароснижающих препаратов. Дозы инсулина рассчитывает врач-эндокринолог.</p>",
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},
"code": "H16",
"name": "Кератит",
"icd_name": "Кератит",
"gender": 0,
"age_min": 1,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "h16_keratit",
"lead": "заболевание роговой оболочки глаза воспалительного характера, проявляющееся преимущественно болью и покраснением глаза, помутнением и изъязвлением роговицы",
"description": "<p><span id=\"docs-internal-guid-d622b4ee-7fff-e7b3-1602-de4b76c0153c\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Кератит — это воспалительное заболевание роговицы, которое характеризуется ее помутнением, а также ухудшением зрения.</span></span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">На появление патологии могут повлиять различные факторы, которые условно можно разделить на внешние и внутренние. В одной ситуации кератит будет развиваться как самостоятельное заболевание (экзогенная группа кератитов), в другом — как осложнение общего заболевания организма (эндогенная группа кератитов).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основные внешние факторы:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Бактерии — пневмококки, стрептококки, стафилококки; гемофильная, синегнойная и кишечная палочки и т. п.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Вирусы — простой герпес, аденовирус, корь и т. д.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Грибы — аспергиллы, плесневые грибки, фузарии, кандиды и т. п.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Простейшие организмы — токсоплазмы, лейшмании, глисты, амебы и т. п.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Механические и термические травмы глаза и, в частности, роговицы.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Несоблюдение гигиены глаз (прикасание грязными руками, неправильное использование контактных линз и прочее).</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основные внутренние факторы:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Аллергические процессы (аллергический ринит, медикаментозная аллергия и т. д.).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Аутоиммунные заболевания (синдром Шегрена, ревматоидный артрит и т. д.).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Офтальмологические заболевания (дистрофия роговицы, блефарит, конъюнктивит и т. д.).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Патологии при нарушении обменных процессов (сахарный диабет, псориаз и т. д.).</span></li>\r\n</ul>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В роговой оболочке появляются отек и инфильтраты. Инфильтраты состоят преимущественно из лимфоидных клеток, полинуклеарных лейкоцитов и небольшого количества плазматических клеток, а также из измененных клеток стромы роговицы. Эпителий над инфильтратами может отслаиваться и слущиваться, появляются эрозии, роговица становится шероховатой и теряет свой блеск. После развития инфильтрата или одновременно с ним из конъюнктивы и склеры в роговую оболочку врастают поверхностные и глубокие сосуды. Небольшие поверхностные инфильтраты обычно рассасываются бесследно, глубокие - оставляют помутнения различной выраженности.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При осложнении гнойной инфекцией инфильтраты протекают с некрозом ткани роговицы и обычно изъязвляются. Язвенный дефект в дальнейшем заполняется рубцовой тканью, образуя лейкому.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для того, чтобы диагностировать заболевание на ранней стадии, определить очаг поражения, проводят:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">бактериологическое исследование</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">бактериоскопическое исследование</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">биомикроскопию</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">зеркальную микроскопию заднего эпителия роговицы</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">иммунологические исследования</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">кожно-аллергические пробы</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">пробу с флюоресцеином</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">цитологическое исследование эпителия конъюнктивы и роговицы</span></li>\r\n</ul>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для корректного назначения лечения заболевания важно определить причину его возникновения. Так при инфекционных (бактериальном, вирусном и грибковом) кератитах назначают антибактериальную, противовирусную или противогрибковую терапию; при аллергических ­— антигистаминные и гормональные препараты и т. д. Точную схему лечения может разработать только специалист после проведения обследования.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При этом лечение может состоять из медикаментозной терапии в виде использования глазных капель и мазей, таблеток или внутривенных инъекций, а также хирургического лечения — кератопластика (трансплантация роговицы), лазерокоагуляция (шлифовка роговицы) и т. д. Операции проводятся только в том случае, если консервативные методы не дали положительного результата.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика кератита заключается, во-первых, в предупреждении травм (в т.ч. микротравм) глаза. При выполнении различных работ (электросварка, резка металла и дерева электроинструментом, работа с химикатами и др.) следует пользоваться защитными очками. Так же следует обращать внимание на здоровье своих глаз: своевременно обращаться к врачу и проводить лечение блефарита, конъюнктивита, дакриоцистита, иммунодефицитных состояний и различных заболеваний, способствующих развитию эндогенного кератита.</span></p>",
"clinical_picture": "<ul>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Болевые ощущения в глазах. Это наиболее распространенное проявление заболевания: человек чувствует резь, покалывания, возникает ощущение, что в глазах есть инородное тело.</span></li>\r\n<li><span style=\"background-color: transparent; font-size: 7pt; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Покраснение склеры. Глаза краснеют, роговица становится тусклой.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Светобоязнь. Яркий свет вызывает болезненные ощущения.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Слезоточивость.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Непроизвольное смыкание век (рефлекторный блефароспазм).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Пониженная чувствительность роговицы.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При осмотре офтальмолог может заметить на роговице следы крови или лимфы. Из-за этих инфильтратов острый кератит может вызвать рубцевание ткани: это негативно скажется на зрении и может привести к необходимости операции.</span></p>",
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},
"code": "E15",
"name": "Недиабетическая гипогликемическая кома",
"icd_name": "Недиабетическая гипогликемическая кома",
"gender": 0,
"age_min": 20,
"age_max": 75,
"cause": [
0
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"periodicity": 1,
"slug": "e15_nediabeticheskaya_gipoglikemicheskaya_koma",
"lead": " Заболевание, характеризующееся приступами гипогликемии, обусловленными абсолютным или относительным повышением уровня инсулина.\r\n",
"description": "",
"etiology": "<p>Опухоли островков Лангерганса (инсулиномы)</p>\r\n<p>диффузная гиперплазия бета-клеток поджелудочной железы</p>\r\n<p>заболевания ЦНС, печени, внепанк-реатические опухоли</p>\r\n<p>секретирующие инсулиноподобные вещества, опухоли (чаще соединительно-тканного происхождения), усиленно поглощающие глюкозу</p>\r\n<p>недостаточная продукция контринсулярных гормонов.<br /><br /></p>",
"pathogenesis": "<p>Гипогликемия приводит к нарушению функционального состояния ЦНС, повышению активности симпатико-адреналовой системы.<br /><br /></p>",
"diagnostics": "<p>Для диагностики проводят определение уровня сахара в крови, иммунореактивного инсулина и С-пептида (натощак и на фоне пробы с голоданием и глюкозотолерантного теста). Для топической диагностики используют ангиографию поджелудочной железы, ультразвуковое исследование, компьютерную томографию, ретроградную панкреатодуоденографию.<br /><br /></p>",
"treatment": "<p>Лечение инсулиномы и опухолей других органов, обусловливающих развитие гипогликемических состояний, хирургическое. При функциональном гиперинсулинизме назначают дробное питание с ограничением углеводов, кортикостероиды (преднизолон по 5-15 мг/сут). Приступы гипогликемии купируют внутривенным введением раствора глюкозы.</p>",
"prevention": "",
"clinical_picture": "<p>Начало приступа характеризуется ощущением голода, потливостью, слабостью, дрожанием конечностей, тахикардией, чувством страха, бледностью, диплопией, парестезиями, психическим возбуждением, немотивированными поступками, дезориентацией, дизартрией; в дальнейшем наступают <a href=\"/symptom/obmorok/\" title=\"Перейти на страницу симптома Обморок\">потеря сознания</a>, клинические и тонические судороги, иногда напоминающие эпилептический припадок, <a href=\"/symptom/koma/\" title=\"Перейти на страницу симптома Кома\">кома</a> с гилотермией и гипорефлексией. Иногда приступы начинаются с внезапной потери сознания. В межприступном периоде появляются симптомы, обусловленные поражением ЦНС: снижение памяти, эмоциональная неустойчивость, <a href=\"/symptom/prostraciya/\" title=\"Перейти на страницу симптома Прострация\">безразличие</a> к окружающему, потеря профессиональных навыков, нарушения чувствительности, парестезии, симптомы пирамидной недостаточности, патологические рефлексы.<br /><br /></p>",
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5132
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