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},
"code": "K65",
"name": "Перитонит",
"icd_name": "Перитонит",
"gender": 0,
"age_min": 15,
"age_max": 100,
"cause": [
"3"
],
"periodicity": 1,
"slug": "k65_peritonit",
"lead": "воспаление брюшины, которое может привести к нарушению разных функций организма",
"description": "<p><span id=\"docs-internal-guid-55be9941-7fff-462b-011e-2225c5d2f59c\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Перитонит – это воспаление листков брюшины - ткани, которая выстилает внутреннюю поверхность живота (париетальный листок брюшины) и покрывает большую часть органов брюшной полости (висцеральный листок брюшины).</span></span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заболевание возникает при попадании патогенной микрофлоры, желчи, ферментов поджелудочной железы или содержимого кишечника в брюшную полость. Обычно инфекция проникает изнутри, при разрыве или расплавлении органа, с излитием его содержимого. Реже инфекция заносится при ранениях, операциях, травмах. Возбудителями заболевания обычно являются стафилококки, гонококки, кишечная палочка, другие патогенные микроорганизмы.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Острый перитонит вызывают:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">аппендицит;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">разрывы кишки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">прободение язвы желудка;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">гнойные процессы в органах малого таза;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">холецистит;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">панкреатит.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В начале заболевания возникает интоксикация организма. Процесс нагноения стремительно поражает организм токсинами, иммунитет резко ухудшается. Начальная стадия проявляется отеками брюшины, стойким парезом кишечника, понижением артериального давления и расстройством гемодинамики.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ухудшение работы печени вызывает снижение качества выработки белка. Возрастает содержание а-аминоуксусной кислоты и аммония в крови. Клетки надпочечников изменяются, легкие отекают, ухудшается сердечно-сосудистая деятельность. Перестраивается работа нервной системы, возникают адинамия, гиперкалиемия, гипокалиемия и другие заболевания, связанные с пониженной концентрацией ионов калия в крови.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">На последних стадиях перитонита в канальцах почек накапливается нерастворимый белок, что приводит к развитию острой почечной недостаточности. Нарушается метаболизм, организм накапливает промежуточные продукты обмена веществ.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Врач проводит осмотр пациента, пальпацию брюшной полости, определяет характер боли. При необходимости проводится вагинальное или ректальное исследование.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дополнительно пациентам могут быть назначены следующие анализы при перитоните:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">исследование мочи и крови;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">рентгенография;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">УЗИ органов брюшной полости;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">диагностическая лапаротомия.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пациента с признаками заболевания немедленно госпитализируют в стационар и начинают готовить к операции. Самолечение недопустимо и может привести к смертельному исходу.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Запрещено самостоятельно пить анальгетики, принимать горячие ванны, прикладывать тепло для снятия боли, так как эти меры могут размыть симптомы, что затруднит диагностику и может стоить пациенту жизни.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение в данном случае только оперативное. Целью операции при перитоните является выявление и купирование источника развития заболевания (удаление аппендикса, ушивание кишечника, желудка и так далее).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">После этого проводится многократное промывание брюшной полости антисептическими растворами для окончательного устранения инфекции. Затем необходимо обеспечить дренирование малого таза и брюшной полости. </span><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Через установленные во время операции дренажные трубки брюшную полость промывают растворами антисептиков для профилактики осложнений. До операции и после ее окончания показано проведение консервативного лечения.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика строится на раннем выявлении и качественном лечении основного заболевания. Постоперационного перитонит предупреждается качественной санацией брюшной полости, гемостазом и тщательным проведением абдоминальных операций.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Клиническая картина зависит от фазы заболевания. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Первые признаки и симптомы перитонита следующие:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">боли в животе, которые усиливаются при движении и дыхании, пациенту комфортнее всего лежать на спине или в позе эмбриона;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">раздражительность, общая слабость, ухудшение состояния;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">повышение температуры тела;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">частое дыхание, тахикардия;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">тошнота, рвота.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При наступлении второй стадии заболевания состояние пациента ухудшается. Появляются признаки сильной интоксикации, боли усиливаются, возникает анемия и вздутие живота. Давление снижается, пульс по-прежнему повышен, начинается неукротимая рвота.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Во время третьей стадии внутренние резервы организма полностью истощаются. Кожа бледная, температура снижается ниже нормы, у пациента наблюдается помутнение сознания, он перестает реагировать на внешние раздражители. Для этой стадии почти неизбежен летальный исход.</span></p>",
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},
"code": "K73",
"name": "Хронический гепатит",
"icd_name": "Хронический гепатит, не классифицированный в других рубриках",
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2,
7,
8,
9,
10
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"lead": "Поражение гепатоцитов, вызванное различными причинами, характеризующееся гепатоцеллюлярным некрозом и воспалением, длящееся более 6 месяцев",
"description": "",
"etiology": "<p>Вирусы гепатитов В, С, Д, Е, аутоиммунные реакции, токсины и лекарственные средства.</p>",
"pathogenesis": "<p>Под воздействием повреждающих агентов происходят цитолиз и некробиоз гепатоцитов. На фоне длительно существующего хронического гепатита часто развивается цирроз печени.</p>",
"diagnostics": "<p>Проводится на основании жалоб, данных анамнеза, объективного осмотра, лабораторно-инструментальных методов исследования. Необходимо провести биохимическое исследование крови с исследованием уровня прямого и непрямого билирубина, АЛТ, холестерина, щелочной фосфатазы. Обязательными являются проведение тимоловой пробы, оценка сулемового титра. Проводят серологическое исследование крови, электронную иммунную микроскопию. В моче определяют уровень уробилиногена.</p>\r\n<p> </p>\r\n<p>Одним из важнейших методов диагностики является биопсия печени.</p>\r\n<p>Дифференциальная диагностика</p>\r\n<p>Проводится с циррозом печени, острыми гепатитами А, В, С, Д, Е, гастроэнтеритом, а также с надпеченочной или подпеченочной желтухой.</p>",
"treatment": "<p>Необходимо соблюдение диеты. При хроническом вирусном гепатите назначают интерферон—2α.</p>",
"prevention": "",
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4948
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"code": "F83",
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3
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{
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},
"code": "K80",
"name": "Желчекаменная болезнь",
"icd_name": "Желчекаменная болезнь [холелитиаз]",
"gender": 0,
"age_min": 20,
"age_max": 100,
"cause": [
"0",
"3"
],
"periodicity": 1,
"slug": "k80_zhelchekamennaya_bolezn",
"lead": "заболевание, характеризующееся образованием камней в желчном пузыре и желчных протоках",
"description": "<p>Желчекаменная болезнь - это хроническое заболевание желчевыводящих путей, характеризующееся нарушением обмена веществ в организме и образованием камней.<span style=\"color: #444444; font-family: Inter, sans-serif; font-size: 16px; text-align: justify;\"><br /></span></p>",
"etiology": "<p>Желчнокаменная болезнь относится к весьма распространенным заболеваниям людей старше 40–50 лет. Женщины болеют приблизительно в 3 раза чаще мужчин. В большинстве своем камни образуются в желчном пузыре, реже – в общем желчном протоке и очень редко – в других протоках.</p>\r\n<p>В развитии холелитиаза имеют значение воспалительные процессы в желчевыводящей системе, изменение pH пузырной желчи, гидролиз конъюгатов билирубина и фосфолипидов, повышение концентрации кальция в желчи и повышение всасывания желчнокислых солей, заброс панкреатического сока в желчный пузырь с развитием воспаления и образованием желчных камней, выделение перенасыщенной холестерином желчи самой печенью. В развитии холестериновых камней большую роль играют характер питания (употребление высококалорийной, богатой углеводами и жирами пищи), малоподвижный образ жизни. Желчные камни нередко образуются при гемолизе, когда в желчь поступает большое количество желчных пигментов.</p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Желчь, синтезируемая клетками печени, по правому и левому долевым протокам попадает в общий печёночный проток. Далее через пузырный проток она временно откладывается в желчном пузыре. Во время приёма пищи желчный пузырь сокращается, и желчь по общему желчному протоку через большой дуоденальный сосок попадает в двенадцатиперстную кишку, где и связывается с пищей. Основная роль желчи - расщепление жиров.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">По различным причинам, чаще всего из просвета двенадцатиперстной кишки, в желчный пузырь попадают патогенные микроорганизмы, формируя «бактериальное ядро» будущего желчного камня. В связи с наличием в просвете желчного пузыря хронического инфекционного воспаления нарушается его сократительная функция. Желчь застаивается, способствуя увеличению числа конкрементов и их размеров. </span></p>",
"diagnostics": "<p>Основным способом диагностики желчнокаменной болезни является ультразвуковое исследование. При этом в просвете желчного пузыря определяются плотные эхоструктуры, перемещающиеся при изменении положения тела. Информативность метода составляет 96–98 %. Одним из важнейших методов диагностики является рентгенологическое исследование. Иногда желчные камни можно видеть на обзорной рентгенограмме. Во многих случаях камни обнаруживаются при холецистографии или холеграфии. Перспективным методом является ретроградная холангиография при помощи специального фиброскопа.</p>",
"treatment": "<p>Консервативное лечение проводят при отсутствии серьезных осложнений. Оно направлено на устранение нарушений моторной функции желчевыводящих путей, улучшение оттока желчи и уменьшение воспалительного процесса в билиарной системе.</p>\r\n<p>В период желчной колики назначают антиспастические средства. При длительном болевом синдроме и особенно при лихорадке показано назначение антибактериальных препаратов. Большое значение в лечении желчнокаменной болезни имеет диета (диета № 5) с исключением острых, жирных, соленых блюд. Лечение на курортах с минеральными водами, занятия лечебной физкультурой, физиопроцедуры дают благоприятный результат при умеренно выраженном болевом синдроме.</p>\r\n<p>Абсолютные показания к экстренному хирургическому лечению: местный или разлитой перитонит, угроза перфорации при деструктивной форме острого холецистита, эмпиема или водянка желчного пузыря, илеус на почве желчных камней.</p>",
"prevention": "<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">не практиковать длительное лечебное голодание; </span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">пить достаточно жидкости, не менее 1.5л в день;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">чтобы не спровоцировать движение камней, избегать работ, связанных с продолжительным пребыванием в наклонном положении;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">соблюдать диету, нормализовать массу тела;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">увеличить физическую нагрузку; </span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">питаться чаще, каждые 3-4 часа, чтобы вызывать регулярные опорожнения пузыря от накопившейся желчи;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">женщинам стоит ограничить поступление эстрогенов, данный гормон способствует образованию камней или их увеличению;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">полезно включать в ежедневный рацион небольшое количество (1-2ч.л.) растительного масла, лучше оливкового. Подсолнечное усваивается только на 80%, в то время как оливковое полностью. Поступление растительного жира стимулирует активность пузыря с желчью, в результате чего он получает возможность хотя бы раз в сутки опорожниться, предупреждая застойные явления и образование камней;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">в рацион питания стоит включить магний. Микроэлемент стимулирует моторику кишечника и выработку желчи, выводит холестерин. Кроме того, для выработки желчных ферментов необходимо достаточное поступление;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">отказаться от употребления кофе. Напиток стимулирует сокращение пузыря, что может вызвать закупорку протока и последующий приступ.</span></p>\r\n</li>\r\n</ul>",
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"lead": "Нарушение здоровья, относящееся к группе болезни желчного пузыря, желчевыводящих путей и поджелудочной железы",
"description": "Острый панкреатит — стремительно развивающееся воспаление поджелудочной железы, обусловленное поражением органа собственными ферментами, заболевание без лечения может угрожать жизни пациента. Заболевание возникает чаще в возрасте 30—60 лет, причем у женщин в 2 раза чаще, чем у мужчин.",
"etiology": "<p>Факторы, способствующие возникновению острого панкреатита:</p>\r\n<ul>\r\n<li>злоупотребление алкоголем (в 70% случаев), вредные пищевые привычки (жирная, острая пища);</li>\r\n<li>заболевания желчевыводящих путей, в том числе желчнокаменная болезнь (в 25-30% случаев);</li>\r\n<li>вирусные (эпидемический паротит, вирус Коксаки) или бактериальные инфекции;</li>\r\n<li>травмы поджелудочной железы;</li>\r\n<li>хирургические вмешательствапо поводу других патологий поджелудочной железы и желчевыводящих путей;</li>\r\n<li>прием эстрогенов, кортикостероидов, тиазидных диуретиков, азатиоприна, других лекарственных средств с выраженным патологическим действием на поджелудочную железу (медикаментозный панкреатит);</li>\r\n<li>врожденные аномалии развития железы, генетическая предрасположенность, муковисцидоз;</li>\r\n<li>воспалительные заболевании органов пищеварения (холецистит, гепатит, гастродуоденит).</li>\r\n</ul>",
"pathogenesis": "<p>В развитии острого воспаления поджелудочной железы основным фактором выступает повреждение клеток преждевременно активированными ферментами самой железы. В нормальных условиях пищеварительные ферменты вырабатываются поджелудочной железой в неактивной форме и активизируются уже в пищеварительном тракте. Под воздействием внешних и внутренних патологических факторов механизм выработки нарушается, ферменты (фосфолипаза А и липаза) активизируются в поджелудочной железе и начинают переваривание ее собственной ткани. Вследствие этого развивается воспаление, отек ткани, поражаются сосуды паренхимы железы.</p>\r\n<p>Патологический процесс при остром панкреатите может распространяться на близлежащие ткани: забрюшинную клетчатку, сальниковую сумку, брюшину, сальник, брыжейку кишечника и связки печении ДПК. Тяжелая форма острого панкреатита способствует резкому повышению уровня различных биологически активных веществ в крови, что ведет к выраженным общим нарушениям жизнедеятельности.</p>\r\n<p> </p>",
"diagnostics": "<p>Лабораторная диагностика:</p>\r\n<p>При исследовании крови в общем анализе отмечаются признаки воспаления (ускорена СОЭ, повышено содержание лейкоцитов), в биохимическом анализе крови обнаруживают повышение активности панкреатических ферментов (амилаза, липаза), возможна гипергликемия и гипокальциемия. Также проводят определение концентрации ферментов в моче. Может отмечаться билирубинемия и повышения активности печеночных ферментов.</p>\r\n<p>При диагностировании острого панкреатита берут биохимический анализ мочи и определяют активность амилазы мочи.</p>\r\n<p>Инструментальная диагностика:</p>\r\n<p>При ультразвуковом исследовании обнаруживают снижение эхогенности паренхимы железы и появление отсутствующего в норме просвета сальниковой сумки за счёт скопления в ней выпота</p>\r\n<p>Рентгеновское исследование брюшной полости обычно малоинформативно, однако иногда позволяет выявить как косвенные признаки воспалительного процесса в поджелудочной железе</p>\r\n<p>КТ имеет преимущество перед ультразвуковым исследованием, так как обеспечивает лучшую специфическую визуализацию ткани поджелудочной железы.</p>\r\n<p>МРТ позволяет оценить уровень тканевого метаболизма, наличие ишемии, некроз панкреатоцитов. Это важно при оценке течения заболевания до развития тяжёлых состояний и осложнений.</p>\r\n<p>Ангиография позволяет установить нарушения кровообращения в поджелудочной железе и окружающих тканях и органах. Эти данные позволяют определиться с прогнозом и тактикой хирургического вмешательства.</p>\r\n<p>ЭГДС относится к дополнительным методам инструментального исследования острого панкреатита.</p>\r\n<p> </p>",
"treatment": "<p>Тактика лечения больных с острым панкреатитом определяется клинико-морфологической формой заболевания в соответствии с фазой развития воспалительного и некротического процесса и степенью тяжести состояния больного. Оптимальным видом лечения ОП в доинфекционной фазе является интенсивная консервативная терапия, а при появлений инфекционных (септических) осложнении – оперативное лечение.</p>\r\n<p>Немедикаментозное лечение: Голод в течение 2-3 суток, постоянное назогастралъное зондирование и аспирация, местная гипотермия (холод на живот). </p>\r\n<p> Для лечения нетяжёлого панкреатита достаточно проведения базисного лечебного комплекса: - анальгетики; - спазмолитики; - инфузионная</p>\r\n<p>Базисную терапию целесообразно усиливать антисекреторной и антиферментной.</p>\r\n<p>При отсутствии эффекта от проводимой базисной терапии в течение 6 часов и наличии хотя бы одного из признаков тяжёлого панкреатита следует констатировать тяжёлый панкреатит и перевести больного в отделение реанимации и интенсивной терапии и проводить лечение, соответствующее тяжёлому острому панкреатиту.</p>\r\n<p>Протокол интенсивной терапии тяжёлого панкреатита</p>\r\n<p>Основной вид лечения - интенсивная консервативная терапия. Приведенный выше базисный лечебный комплекс при тяжёлом ОП является недостаточно эффективным и должен быть дополнен специализированным лечебным комплексом. Эффективность последнего максимальна при раннем начале лечения (первые 12 часов от начала заболевания). Хирургическое вмешательство в виде лапаротомии показано лишь при развитии осложнений хирургического профиля, которые невозможно устранить эндоскопическими методами (деструктивный холецистит, желудочно-кишечное кровотечение, острая кишечная непроходимость и др.).</p>\r\n<p>Специализированное лечение. 1) Антисекреторная терапия (оптимальный срок - первые трое суток заболевания); 2) Антикоагулянты; 3) Возмещение плазмопотери (коррекция водно-электролитных, белковых потерь и др.; 4) Антиферментная, антиоксидантная и антигипоксантная терапия. 5) Детоксикация – при тяжёлом ОП показаны экстракорпоральные методы детоксикации, из которых наиболее эффективным является серийный лечебный плазмаферез. 6) Антибиотикотерапия широкого спектра действия (цефалоспорины III-IV поколений или фторхинолоны II-III поколений в сочетании с метронидазолом).</p>\r\n<p>Хирургическое лечение показано в случае выявления:</p>\r\n<p>камней в желчных протоках; скоплений жидкости в железе или вокруг нее; участков панкреатического некроза, кист, абсцессов.</p>\r\n<p>К операциям, проводимым при остром панкреатите с образованием кист или абсцессов, относятся: эндоскопическое дренирование, марсупиализация кисты, цистогастростомия и др. При образовании участков некроза, в зависимости от их размера, проводят некрэктомию или резекцию поджелудочной железы. Наличие камней является показанием к операциям на протоке поджелудочной железы.</p>\r\n<p>К хирургическому вмешательству могут прибегать и в случае сомнений в диагностики и вероятности пропустить другое хирургическое заболевание, требующее хирургического лечения.</p>",
"prevention": "<p>Первичной профилактикой панкреатита является рациональное здоровое питание, исключение алкоголя, острой, жирной обильной пищи, отказ от курения. Острый панкреатит может развиться не только у лиц, регулярно злоупотребляющих алкоголем, но и как следствие однократного приема спиртосодержащих напитков под жирную, жареную и острую закуску в больших количествах.</p>",
"clinical_picture": "<p>Характерные симптомы острого панкреатита.</p>\r\n<ul>\r\n<li>Болевой синдром. Боль может локализоваться в эпигастрии, левом подреберье, нередко носит опоясывающий характер, может отдавать под левую лопатку. Боль носит выраженный постоянный характер, в положении лежа на спине усиливается. Усиление боли происходит и после приема пищи, особенно – жирной, острой, жареной, алкоголя.</li>\r\n<li>Тошнота, рвота. Рвота может быть неукротимой, содержит желчь, не приносит облегчения. Как правило, из-за интоксикации и рвоты наступает нарушение водно-электролитного баланса, обезвоживание, которое играет важную роль в патогенезезаболевания.</li>\r\n<li>Повышение температуры тела.</li>\r\n<li>Умеренно выраженная желтушность склер. Редко – легкая желтуха кожных покровов.</li>\r\n</ul>\r\n<p>Кроме того, острый панкреатит может сопровождаться диспепсическими симптомами (вздутие живота, метеоризм, изжога), кожными проявлениями (синюшные пятна на левой боковой стенке живота, иногда с желтоватым оттенком, кровоизлияния в области пупка).</p>",
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"standard_type": 3,
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}
]
}
