ВОзвращает список болезней. Можно фильтр/искать

search, age, gender, parent, symptoms, sort_name, sort_by, rand, branches
GET /disease/?format=api&ordering=published&page=525
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

{
    "count": 11794,
    "next": "http://api.symptomd.ru/disease/?format=api&ordering=published&page=526",
    "previous": "http://api.symptomd.ru/disease/?format=api&ordering=published&page=524",
    "results": [
        {
            "id": 13015,
            "symptoms": [
                {
                    "id": 2595,
                    "synonyms": [
                        {
                            "name": "Аорталгия"
                        },
                        {
                            "name": "Боль в грудной клетке"
                        },
                        {
                            "name": "Грудная боль"
                        },
                        {
                            "name": "Боль в груди при вдохе"
                        },
                        {
                            "name": "Боль в груди при кашле"
                        },
                        {
                            "name": "Боль в грудине"
                        },
                        {
                            "name": "Грудина болит"
                        },
                        {
                            "name": "Грудь болит"
                        },
                        {
                            "name": "Боль в области груди"
                        }
                    ],
                    "body_points": [
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                            "y": 2795,
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                    ],
                    "disease_count": 55,
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                    "name": "Боль в груди     ",
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                    "lead": "Чувство боли или давления в грудной клетке симптом многих заболеваний как незначительных так и очень серьезных, поэтому обязательно проконсультируйтесь со специалистом",
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                },
                {
                    "id": 2758,
                    "synonyms": [
                        {
                            "name": "лимфаденопатия"
                        },
                        {
                            "name": "увеличение лимфоузлов"
                        },
                        {
                            "name": "лимфоузел воспаление"
                        },
                        {
                            "name": "лимфоузлы набухли"
                        },
                        {
                            "name": "увеличились лимфоузлы"
                        }
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                    "name": "Увеличение лимфатических узлов ",
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                    "slug": "uvelichenie_limfaticheskih_uzlov",
                    "lead": "Воспаление лимфатических узлов свидетельствует о проблемах в зоне, которую \"обслуживает\" узел. Чаще всего увеличение лимфоузла связано инфекцией, реже оно является следствием опухолевого поражения",
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                {
                    "id": 2737,
                    "synonyms": [
                        {
                            "name": "Жар"
                        },
                        {
                            "name": "Озноб"
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                        {
                            "name": "Лихорадит"
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                    ],
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                    "lead": "Различают три стадии лихорадочной реакции: повышение температуры, затем появляется ощущение жара, на третьей стадии снижение температуры в следствии повышения теплоотдачи, процесс носит циклический характер",
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                {
                    "id": 3186,
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                        {
                            "name": "Грудь набухла и болит"
                        },
                        {
                            "name": "Набухает грудь при менструации"
                        },
                        {
                            "name": "Правая грудь набухла"
                        },
                        {
                            "name": "Левая грудь набухла"
                        },
                        {
                            "name": "Грудь увеличилась в размере"
                        },
                        {
                            "name": "Уплотнения в груди"
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            },
            "code": "N64.4",
            "name": "Мастодиния",
            "icd_name": "Мастодиния",
            "gender": 2,
            "age_min": 11,
            "age_max": 100,
            "cause": [
                "0"
            ],
            "periodicity": 3,
            "slug": "n64.4_mastodiniya",
            "lead": "циклически возникающие или постоянные боли в молочных железах, вызванные колебанием уровня гормонов или патологическими процессам и в груди, других органах",
            "description": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Мастодиния &ndash; синдром, при котором женщины испытывают дискомфорт в области молочных желез (отечность, уплотнение, боль в груди, повышенная чувствительность). Причиной недомогания часто является задержка жидкости в организме. Может проявляться перед началом менструации, быть признаком полового созревания у девочек, беременности, невроза, или являться проявлением какого-либо нарушения в организме.</span></p>",
            "etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причин для развития мастодинии достаточно много, основные из них:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">резкие гормональные колебания во время пубертата, беременности, климакса,</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">воспалительные процессы в области молочной железы (маститы неинфекционные или гнойные),</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">доброкачественные или злокачественные опухоли железы (аденомы, рак),</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">травмы, операции на железе, в том числе и пластика груди,</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">проявления предменструального синдрома,</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">медицинские аборты, искусственные роды,</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">прием оральных контрацептивов, стимуляторов овуляции или диуретиков,</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">большой размер груди при неправильно подобранном белье,</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">отраженные боли при миалгиях, остеохондрозе, межреберной невралгии, сердечной боли,</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">болезни печени и почек, обменные нарушения (особенно связанные с метаболизмом жиров),</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">стрессы и неврозы.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">&nbsp;</span></p>",
            "pathogenesis": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Механизм появления боли при физиологической или дисгормональной мастодинии связан с изменениями, происходящими в ткани молочных желез под действием половых гормонов, особенно прогестерона. В лютеиновую фазу овариального цикла наблюдается активная пролиферация эпителиальных клеток груди, в строме задерживается жидкость. Это приводит к набуханию грудных желез, сдавливанию нервных окончаний и возникновению болевых ощущений. При наличии органических изменений в тканях боль обусловлена раздражением ноцицептивных рецепторов продуктами метаболизма, которые образуются при воспалительных и некротических процессах, или давлением растущего объемного образования на окружающие ткани.</span></p>",
            "diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основная задача диагностического этапа при подозрении на мастодинию &mdash; исключение органических причин появления болей в груди. С этой целью назначается полный комплекс лабораторно-инструментальных исследований и консультаций, позволяющих обнаружить болезни молочных желез и другую патологию. В план обследования обычно включают такие методы, как:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">УЗИ молочных желез. Сонография дает возможность быстро оценить структуру тканей груди, выявить объемные образования, уточнить их форму, размеры, локализацию, определить увеличение лимфоузлов.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Маммография. Наиболее чувствительный способ обнаружения даже небольших объемных образований. Выполняется в двух или трех проекциях. При необходимости делается прицельный снимок.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лабораторные анализы. На цитологическое исследование отправляют выделения из соска и биоптат, полученный методом пункционной или трепан-биопсии. Определяется уровень онкомаркера CA 15-3 в крови.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При наличии соответствующего оборудования в качестве скринингового метода используют радиотермометрию молочных желез. В сложных диагностических случаях показаны КТ, МРТ, электроимпедансная маммография, сцинтиграфия груди, оценка гормонального профиля (содержания эстрадиола, прогестерона, свободного и связанного тестостерона, ФСГ, ЛГ, гормонов щитовидной железы и др.).</span></p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">&nbsp;</span></p>",
            "treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Специальная терапия масталгии начинается только после исключения болезней молочных желез. При незначительном болевом синдроме и отсутствии других расстройств женщинам с истинной мастодинией рекомендовано наблюдение в динамике с периодическим осмотром маммолога и проведением УЗИ или маммографии. Врачебная тактика при выраженной боли и эмоциональных нарушениях направлена на уменьшение или устранение субъективно неприятных ощущений в груди, возникающих при колебаниях гормонального фона. Наиболее эффективным считается сочетание патогенетического гормонального, медикаментозного негормонального и немедикаментозных методов лечения. Таким пациенткам показаны:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гормонотерапия. Выбор препарата выполняется с учетом уровня секреции гормонов и выраженности симптоматики. Для лечения применяют комбинированные оральные контрацептивы монофазного типа или рилизинг-формы, гестагены, антиэстрогены, агонисты гонадотропин-рилизинг фактора.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Фитопрепараты и гомеопатические средства. Для коррекции дисгормональных расстройств используют производные растений с эстрогеноподобным эффектом (примулы вечерней, шалфея, душицы, цимифуги) и гомеопатические препараты, в состав которых они входят. Их рекомендуют при отказе женщины от гормонотерапии.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Седативные препараты. При наличии значительных колебаний настроения, склонности к тревоге и ипохондрии показаны селективные ингибиторы обратного захвата норадреналина и серотонина. В более мягких клинических случаях эффективны препараты магния, успокоительные сборы и травы (валериана, пустырник, пион).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Анальгетики. Женщинам с выраженным болевым синдромом назначают медикаменты из группы нестероидных противовоспалительных средств. НПВС стабилизируют клеточные мембраны и угнетают синтез простагландинов, которые снижают порог болевой чувствительности за счет сенсибилизации рецепторов боли к механическим воздействиям.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диуретики. Поскольку одним из звеньев патогенеза мастодинии является задержка жидкости в тканях молочных желез, применение мочегонных средств позволяет уменьшить выраженность болевого синдрома. Обычно используют калийсберегающие диуретики, также обладающие антиандрогенными свойствами, и фитопрепараты.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Комплексную терапию масталгии можно дополнить витаминно-минеральными комплексами и физиотерапевтическими методиками (электрофорезом, магнитотерапией, гальванизацией, бальнеотерапией). При ациклической мастодинии осуществляют лечение основного заболевания с применением соответствующей медикаментозной терапии и хирургических вмешательств (вскрытия и дренирования мастита, энуклеации опухоли, секторальной резекции, мастэктомии и т. д.).</span></p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">&nbsp;</span></p>",
            "prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактические действия должны быть направлены на следующее:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Обязательный и правильный регулярный самоосмотр.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Прохождение УЗ-диагностики женщинам до 40 лет и маммографии после 40 лет 1 раз в год.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Не откладывать поход к врачу при первых настораживающих симптомах.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">&nbsp;</span></p>",
            "clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Характерным проявлением мастодинии является ощущение напряженности в области молочных желез, сопровождающееся болевым синдромом, чувством жара, психологическим и физическим дискомфортом. Боль может иррадиировать в подлопаточную область или плечо. Симптоматика нарастает по мере приближения менструации, однако менее 20% женщин отмечают только нагрубание молочных желез без выраженных болевых ощущений, что обусловлено индивидуальным порогом боли (уровнем раздражения нервной системы).</span></p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пальпация молочной железы определяет уплотнения без четких контуров и границ, выявляется увеличение регионарных лимфоузлов и груди, что обусловлено застойными явлениями. Прослеживается возникновение мигренеподобных головных болей и дискомфорт в кишечнике, сопровождающийся метеоризмом и расстройством стула.</span></p>",
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