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},
"code": "O00",
"name": "Внематочная [эктопическая] беременность",
"icd_name": "Внематочная [эктопическая] беременность",
"gender": 2,
"age_min": 15,
"age_max": 50,
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"3"
],
"periodicity": 1,
"slug": "o00_vnematochnaya_ektopicheskaya_beremennost",
"lead": "патология, при которой развитие беременности происходит вне матки",
"description": "<p>Внематочная беременность - это <span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">патология, при которой оплодотворённая яйцеклетка прикрепляется не в матке, а в маточных трубах, яичнике, шейке матки или брюшной полости.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причина большинства случаев эктопической беременности — нарушение перистальтической функции цилиндрического реснитчатого эпителия, выстилающего маточные трубы. Этому могут способствовать следующие фактора:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">аномалии развития половых органов;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">половой инфантилизм (недостаточное развитие половых органов) — маточные трубы длинные, узкие и извитые, что затрудняет прохождение по ним оплодотворённой яйцеклетки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">перенесённые хирургические и медикаментозные прерывания беременности приводят к повреждению слизистой матки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">рецидив эктопической беременность (если была выполнена пластика маточной трубы);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">воспалительный процесс в придатках матки приводит к образованию спаек (препятствий) на пути движущейся яйцеклетки, также нарушается перестальтика — сокращение маточных труб, способствующая продвижению оплодотворённой яйцеклетки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">эндометриоз и аденомиоз сказываются на качестве яйцеклеток, правильной перестальтике маточных труб и повреждают матку;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">беременность, наступившая после хирургической стерилизации (перевязки маточных труб);</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">дисгормональные сбои приводят к рассинхронизации работы женских половых органов — оплодотворение происходит, но прикрепиться к эндометрию эмбрион не может и имплантируется за пределами матки;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">сочетанные гинекологические патологии;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">возникновение опухолей и опухолевидных образований в матке и её придатках, органах брюшной полости;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">вредные и тяжёлые условия труда, работа в ночную смену — нарушается работы эндокринной системы;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">курение — никотин негативно влияет на качество ооцитов и нарушает сократительную функцию маточных труб.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Также в группе риска находятся женщины, которые столкнулись со внематочной беременностью ранее и использующие внутриматочную спираль. </span></p>",
"pathogenesis": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При отсутствии патологических факторов, ядра яйцеклетки и сперматозоида сливаются в ампулярном отделе фаллопиевых труб, затем происходит миграция уже оплодотворённой яйцеклетки, и она имплантируется в полость матки. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Транспортную функцию выполняют реснички эпителия, покрывающие фаллопиевы (маточные) трубы. Вследствие нарушения или снижения перистальтики эпителия появляется риск развития эктопической беременности.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Вместилище для плода, если тип беременности трубный, образуется непосредственно из оболочек фаллопиевых труб.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагностика внематочной беременности проводится с использованием таких методов:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">гинекологический осмотр, выявляющий отсутствие признаков маточной беременности и патологическое образование, например, в трубе;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">УЗИ, дающее возможность определить патологию с 1 – 2 недели задержки менструации, когда в матке не обнаруживается плодное яйцо;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">анализ на ХГЧ с промежутком в 48 часов, в норме показатель за это время удваивается, при внематочной беременности прирост его в крови не столь велик.</span></li>\r\n</ul>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение внематочной беременности только хирургическое. К нему прибегают, как при неосложненной внематочной беременности без кровотечения (в случае своевременной диагностики), так и при наличии кровотечения.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К оперативным методам лечения внематочной беременности относится:</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">1. Лапароскопия.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Это «золотой стандарт» современной гинекологии, который отличается малой травматичностью, минимумом болевых ощущений и коротким реабилитационным периодом. Операция проходит быстро в условиях дневного стационара.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">2. Сальпинготомия.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Применяется только на ранних этапах развития внематочной беременности. Представляет собой сегментарное удаление фаллопиевой трубы вместе с зиготой (оплодотворенной яйцеклеткой), с последующим восстановлением ее проходимости.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">3. Сальпингоэктомия.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Сальпингэктомию выполняют при обширном повреждении маточной трубы.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">4. Лапаротомия.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Это классическое хирургическое вмешательство, которое применяется в случае нахождения зиготы в добавочном роге матки, при наличии выраженного спаечного процесса и обильном внутреннем кровотечении.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Выбор хирургического метода лечения внематочной беременности зависит от степени внутреннего кровотечения, срока беременности и места локализации эмбриона.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Исходя из факторов риска, приводящих к эктопической беременности, можно составить список правил, которые стоит соблюдать для её предупреждения:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">первостепенно, при подготовке к зачатию ребёнка необходимо выполнить полное обследование, обязательно включающее в себя трансвагинальное УЗИ, в целях выявления патологий со стороны мочеполовой системы, а также уточнения анатомо-физиологических особенностей (двурогая матка);</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">избегать сомнительных половых связей, чтобы не допустить развитие инфекции, использовать средства барьерной контрацепции;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">необходимо своевременно и правильно проводить лечение воспалительных заболеваний половых органов, наблюдаться у врача-гинеколога и не заниматься самолечением;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">в случае необходимости проведения прерывания беременности отдавать выбор наименее травматичным методикам, выполнять все назначения врача в послеоперационный период;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">снизить количество стрессовых факторов, по возможности отказаться от работы в ночное время суток, соблюдать режим труда и отдыха;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отказаться от табакокурения.</span></li>\r\n</ul>",
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"code": "O01",
"name": "Пузырный занос",
"icd_name": "Пузырный занос",
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0
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"lead": "Пузырный занос – патология плодного яйца, характеризующаяся трансформацией ворсин наружной зародышевой оболочки (хориона) в цисты - содержащие жидкость пузырьки, разрастанием ворсин, гибелью плода.",
"description": "Выделяют два вида пузырных заносов: полный и частичный. Наиболее частая форма пузырного заноса — полный пузырный занос.",
"etiology": "<p>Пузырный занос наиболее часто встречается среди опухолей трофобласта, причиной его развития служат генетические нарушения беременности. Пузырный занос локализуется в матке (реже в маточной трубе), чаще возникает у юных и возрастных беременных, в плохой социальноэкономической среде. Пузырный занос не обладает инвазивным ростом, не метастазирует. Частота излечения — 100%.</p>",
"pathogenesis": "<p>Патогенез пузырного заноса не выяснен.</p>",
"diagnostics": "<p>Для постановки диагноза пузырного заноса необходимо:<br />· оценить клинические симптомы во время беременности;<br />· провести УЗИ, КТ органов малого таза;<br />· определить концентрацию ХГЧ в сыворотке крови (при нормальной беременности пик ХГЧ отмечают в 9–10 нед, он не выше 150 000 мМЕ/мл, в дальнейшем концентрация снижается).</p>",
"treatment": "<p>· вакуум-экстракция пузырного заноса с контрольным острым кюретажем;<br />· гистологическое исследование материала;<br />· пациентки с резусотрицательной кровью и частичным пузырным заносом должны получать Rh0-(анти-D)-Ig;<br />· в последующем — тщательный мониторинг в течение года.</p>",
"prevention": "<p>В настоящее время не разработана.</p>",
"clinical_picture": "<p>Основные клинические симптомы пузырного заноса обычно возникают перед 18 нед беременности:<br />· влагалищное <a href=\"/symptom/krovotechenie/\" title=\"Перейти на страницу симптома Кровотечение\">кровотечение</a> (более 90% случаев);<br />· размеры матки превышают должные для данного срока беременности (в 50% случаев);<br />· двухсторонние кисты 8 см и более (20–40%).</p>\r\n<p>При пузырном заносе могут развиться различные осложнения:<br />· неукротимая <a href=\"/symptom/rvota/\" title=\"Перейти на страницу симптома Рвота\">рвота</a> беременных (20–30% случаев);<br />· АГ, преэклампсия (10–30%);<br />· симптомы гипертиреоза [тёплая кожа, <a href=\"/symptom/tahikardiya/\" title=\"Перейти на страницу симптома Тахикардия\">тахикардия</a>, <a href=\"/symptom/drozhanie/\" title=\"Перейти на страницу симптома Дрожание \">тремор</a>, увеличение щитовидной железы (2–7%)];<br />· разрыв овариальных кист, <a href=\"/symptom/krovotechenie/\" title=\"Перейти на страницу симптома Кровотечение\">кровотечение</a>, инфекционные осложнения;<br />· трофобластическая эмболизация встречается у 2–3% пациенток с острыми дыхательными расстройствами (<a href=\"/symptom/kashel/\" title=\"Перейти на страницу симптома Кашель\">кашель</a>, тахипноэ, <a href=\"/symptom/cianoz/\" title=\"Перейти на страницу симптома Цианоз\">цианоз</a>) при размерах матки, соответствующих сроку 20 и более недель.</p>\r\n<p> </p>",
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