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},
"code": "C82",
"name": "Фолликулярная лимфома",
"icd_name": "Фолликулярная [нодулярная] неходжкинская лимфома",
"gender": 0,
"age_min": 60,
"age_max": 100,
"cause": [
3,
0
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"periodicity": 1,
"slug": "c82_follikulyarnaya_limfoma",
"lead": "Опухоль с низкой злокачественностью, является представителем вида неходжкинских лимфом. ",
"description": "В большинстве случаев фолликулярная лимфома представляет собой совсем не большую группу злокачественных опухолей. Между тем не стоит преуменьшать ее опасности, так, как во многих случаях ей страдают молодые люди. ",
"etiology": "<p>В наши дни принято считать, что основной причиной возникновения фолликулярной лимфомы является иммунологическое воздействие на В-лимфоциты доброкачественным микроокружением. И не маловажным фактором для развития этой болезни может быть приём иммунодепрессантов на протяжении длительного промежутка времени. Такие ситуации вполне возможны после перенесения тяжёлых, трансплантационных операций, к примеру, пересадка почек или сердца.</p>",
"pathogenesis": "",
"diagnostics": "<ol>\r\n<ol>\r\n<li>Врачебный осмотр</li>\r\n<li>Общий клинический и биохимический анализы крови</li>\r\n<li>Биопсия (хирургическое удаление) пораженного лимфатического узла с его последующим морфологическим и иммунологическим исследованием</li>\r\n</ol>\r\n</ol>\r\n<p> </p>\r\n<ol>\r\n<ol>Основным анализом, позволяющим подтвердить диагноз лимфомы, является микроскопическое исследование образца лимфоидной ткани, полученной при биопсии (хирургическом удалении лимфатического узла или кусочка ткани пораженного органа). Эта ткань направляется на морфологическое исследование к врачу-патоморфологу, главной задачей которого является определить: \"Есть ли в изучаемой ткани опухолевые (лимфомные) клетки?\" Если врач находит опухолевые (лимфомные) клетки в изучаемом гистологическом препарате, то следующий вопрос, который он должен решить: \" С каким видом лимфомы мы имеем дело?\"\r\n<li>Лучевая диагностика</li>\r\n</ol>\r\n</ol>\r\n<p> </p>\r\n<ol>\r\n<ol>Лучевая диагностика (рентгенологическое исследование, компьютерная, магнитно-резонансная томография) позволяет выявить наличие опухолевых образований в различных частях тела, которые не доступны врачу при внешнем осмотре.</ol>\r\n</ol>\r\n<ol>Методы лучевой диагностики применяют для определения стадии лимфомы.\r\n<li>Исследование костного мозга также проводится с целью установить: \"Есть ли опухолевые (лимфомные) клетки в костномозговой ткани?\"</li>\r\n<li>Дополнительные методы исследования позволяют уточнить ряд особенностей лимфомы. К ним относятся иммунофенотипирование методом проточной цитометрии, цитогенетические и молекулярно-генетические исследования.</li>\r\n</ol>",
"treatment": "<p>Лечение фолликулярной лифомы зависит от стадии развития, важную роль так же играет форма развития опухоли. Исходя из этих данных, специалисты выбирают тактику лечения. К примеру, если у пациента фоликулярная лимфома проявляется в вялотекущей форме, медики не делают поспешных попыток назначить лечение, на данном этапе применяют тактику выжидания.</p>\r\n<p>Хорошо известно, что фоликулярная лимфома, способна долгое время впадать то в период ремиссии то в рецидив, поэтому точно определить степень заболевания на ранних стадиях довольно проблематично. В это время принято использовать радиотерапию вовлеченных лимфатических узлов.</p>\r\n<p>На более поздних стадиях 3-4 на помощь специалистам приходит полихимиотерапия. Но наиболее распространенным средством, великолепно зарекомендовавшим себя, является так называемая схема СНОР в состав этой схемы входит лечение такими препаратами, как преднизолон, доксорубицин, циклофосфан и винкрестин.</p>\r\n<p>Также в широком применении ходит не менее надежная схема CVP включающая в себя преднизолон, винкристин и циклофосфан.</p>",
"prevention": "",
"clinical_picture": "<p>В большинстве случаев, основными признаками лимфомы, являются увеличенные лимфоузлы, <a href=\"/symptom/potlivost/\" title=\"Перейти на страницу симптома потливость\">потливость</a>, постоянная <a href=\"/symptom/slabost/\" title=\"Перейти на страницу симптома Слабость\">слабость</a> и <a href=\"/symptom/vysokaya_temperatura_38-42/\" title=\"Перейти на страницу симптома Высокая температура 38-42° \">лихорадка</a>. На общие характеристики болезни, в большинстве случаев оказывает сильное влияние местонахождение опухоли.</p>",
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},
"code": "C81",
"name": "Лимфогранулематоз",
"icd_name": "Болезнь Ходжкина [лимфогранулематоз]",
"gender": 0,
"age_min": 20,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "c81_limfogranulematoz",
"lead": "онкогематологическое заболевание, поражающее лимфоциты (основные клетки иммунной системы) и разрушающее лимфатическую систему человека",
"description": "",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Основной причиной развития злокачественной лимфогранулемы считают сбой в защитных системах организма: опухолевые клетки при таком сбое не разрушаются, а продолжают свою жизнедеятельность, минуя механизмы иммунной защиты.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Доказанной связи между развитием лимфомы Ходжкина и внешними факторами (ионизирующее излучение, радиационный фон, воздействие химических агентов) на сегодняшний день не выявлено. Но существуют факторы риска, повышающие вероятность манифестирования данной патологии. К ним относятся:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Вирусные заболевания. Доказана связь развития лимфомы Ходжкина с наличием в организме вируса Эпштейна-Барра (герпесвирус, вызывающий инфекционный мононуклеоз).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Иммунодефицитные состояния, в том числе вызванные СПИДом и приемом иммуносупрессоров.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Генетическая предрасположенность. Механизмов наследственной передачи лимфогранулематоза на сегодняшний день не выявлено, но отмечены случаи параллельного возникновения и развития заболевания у близнецов.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Болезнь Ходжкина чаще поражает молодых людей в возрасте 20-30 лет и лиц старшей возрастной группы (55+). У мужчин заболевание встречается чаще.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для выявления лимфомы Ходжкина специалисты проводят осмотр, опрашивают пациента о проблемах со здоровьем, факторах риска, уточняют дату появления проблем со здоровьем и назначают ряд процедур:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Анализы крови: помогают понять, насколько серьезно успел пострадать организм, определять его способность переносить определенные виды лечения, выявлять нарушения работы почек и печени, а также обнаруживать ВИЧ, гепатит В и С.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Общий анализ: измерение количества различных клеток крови.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">СОЭ – скорость оседания переносящих кислород эритроцитов: необходим для оценки тяжести воспалительных процессов в организме.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Визуализирующие исследования – получение изображений внутренних тканей с помощью рентгеновских лучей, магнитных полей, звуковых волн или радиоактивных частиц. Данные методы используются для поиска причин появления симптомов, определения стадии заболевания, оценки эффективности лечения и поиска признаков рецидива – возвращения лимфомы:</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгенография: позволяет обнаруживать увеличенные лимфатические узлы в грудной клетке и повреждения костей.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Компьютерная томография, КТ – множество рентгеновских снимков, сделанных под разными углами, объединяются в одну подробную «картинку», на которой специалист может обнаружить увеличение лимфоузлов или других органов. КТ обычно назначается для оценки состояния областей шеи, груди, живота и таза.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Магнитно-резонансная томография, МРТ – создание крайне подробного изображения тканей с помощью радиоволн и сильных магнитов. МРТ особенно эффективна при выявлении поражений спинного или головного мозга.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Позитронно-эмиссионная томография, ПЭТ. До проведения процедуры пациенту вводится радиоактивное вещество, которое оседает в измененных клетках. Затем выполняется сканирование, обнаруживающее любое его скопление во всех частях тела.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Биопсия – взятие небольшого количества тканей для исследования свойств их клеток. На сегодняшний день этот метод является единственным способом, позволяющим безошибочно устанавливать диагноз. Образцы забираются из лимфатических узлов, костного мозга или других структур, передаются в лабораторию и тщательно изучаются.</span></li>\r\n</ul>\r\n<p> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Для взрослых и детей используются две основные методики лечения – химиотерапия различными препаратами (блеомицин, циклофосфамид, преднизолон, дакабразин и др.) и лучевая терапия, а также их комбинации. Иногда химиотерапия назначается в сочетании с пересадкой костного мозга. Возраст пациента не является определяющим фактором, большее значение имеют данные лабораторных исследований, тип опухоли, стадия и скорость прогрессирования.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Комбинирование химиопрепаратов и лучевой терапии считается одним из самых прогрессивных и эффективных методов, поскольку позволяет добиться длительной многолетней ремиссии у более чем половины пациентов.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Методов профилактики лимфомы в настоящее время не существует, поскольку до конца не изучены этиологические факторы, ведущие к развитию заболевания.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Признаки заболевания есть не у всех пациентов – люди с подобным диагнозом могут прекрасно себя чувствовать и не иметь никаких проблем со здоровьем. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Со временем, по мере развития лимфомы, нередко появляются следующие симптомы:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Самый частый из них – это опухоль или шишка на шее, подмышкой или в паху, которая представляет из себя увеличенный лимфатический узел</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Лимфатические узлы – это небольшие органы размером с фасоль, выполняющие роль фильтров, задерживающих и уничтожающих вредные для тела вещества. Они представляют из себя скопления лимфоцитов и других клеток иммунной системы, расположенных во всех частях организма, в том числе в шее, груди, животу, тазу и конечностях. Обычно она не доставляет никакого дискомфорта, но может стать болезненной после употребления алкоголя. Постепенно такое новообразование увеличивается, а рядом с ним или в других областях тела возникают новые припухлости.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">В большинстве случаев увеличение лимфоузлов вызвано не опасными опухолями, а обычными инфекциями. Они болят при прикосновении, но возвращаются к своему нормальному размеру после выздоровления.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Так называемые В-симптомы, являющиеся важной частью постановки диагноза и определения прогнозов пациента. Они включают лихорадку – повышение температуры до более чем 38°С на протяжении не менее чем трех дней подряд, сильную ночную потливость и снижение веса без всяких усилий минимум на 10% за последние 6 месяцев.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Кожный зуд.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Потеря аппетита.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">У некоторых людей единственным признаком лимфогранулематоза становится постоянная усталость.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Пораженные грудные лимфоузлы способны опухать, давить на трахею – дыхательное горло, вызывать боль, кашель или даже затруднение дыхания, особенно в положении лежа.</span></li>\r\n</ul>",
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},
"code": "C81",
"name": "Лимфогранулематоз",
"icd_name": "Болезнь Ходжкина [лимфогранулематоз]",
"gender": 0,
"age_min": 20,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "c81_limfogranulematoz",
"lead": "онкогематологическое заболевание, поражающее лимфоциты (основные клетки иммунной системы) и разрушающее лимфатическую систему человека",
"description": "",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Основной причиной развития злокачественной лимфогранулемы считают сбой в защитных системах организма: опухолевые клетки при таком сбое не разрушаются, а продолжают свою жизнедеятельность, минуя механизмы иммунной защиты.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Доказанной связи между развитием лимфомы Ходжкина и внешними факторами (ионизирующее излучение, радиационный фон, воздействие химических агентов) на сегодняшний день не выявлено. Но существуют факторы риска, повышающие вероятность манифестирования данной патологии. К ним относятся:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Вирусные заболевания. Доказана связь развития лимфомы Ходжкина с наличием в организме вируса Эпштейна-Барра (герпесвирус, вызывающий инфекционный мононуклеоз).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Иммунодефицитные состояния, в том числе вызванные СПИДом и приемом иммуносупрессоров.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Генетическая предрасположенность. Механизмов наследственной передачи лимфогранулематоза на сегодняшний день не выявлено, но отмечены случаи параллельного возникновения и развития заболевания у близнецов.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Болезнь Ходжкина чаще поражает молодых людей в возрасте 20-30 лет и лиц старшей возрастной группы (55+). У мужчин заболевание встречается чаще.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для выявления лимфомы Ходжкина специалисты проводят осмотр, опрашивают пациента о проблемах со здоровьем, факторах риска, уточняют дату появления проблем со здоровьем и назначают ряд процедур:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Анализы крови: помогают понять, насколько серьезно успел пострадать организм, определять его способность переносить определенные виды лечения, выявлять нарушения работы почек и печени, а также обнаруживать ВИЧ, гепатит В и С.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Общий анализ: измерение количества различных клеток крови.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">СОЭ – скорость оседания переносящих кислород эритроцитов: необходим для оценки тяжести воспалительных процессов в организме.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Визуализирующие исследования – получение изображений внутренних тканей с помощью рентгеновских лучей, магнитных полей, звуковых волн или радиоактивных частиц. Данные методы используются для поиска причин появления симптомов, определения стадии заболевания, оценки эффективности лечения и поиска признаков рецидива – возвращения лимфомы:</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгенография: позволяет обнаруживать увеличенные лимфатические узлы в грудной клетке и повреждения костей.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Компьютерная томография, КТ – множество рентгеновских снимков, сделанных под разными углами, объединяются в одну подробную «картинку», на которой специалист может обнаружить увеличение лимфоузлов или других органов. КТ обычно назначается для оценки состояния областей шеи, груди, живота и таза.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Магнитно-резонансная томография, МРТ – создание крайне подробного изображения тканей с помощью радиоволн и сильных магнитов. МРТ особенно эффективна при выявлении поражений спинного или головного мозга.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Позитронно-эмиссионная томография, ПЭТ. До проведения процедуры пациенту вводится радиоактивное вещество, которое оседает в измененных клетках. Затем выполняется сканирование, обнаруживающее любое его скопление во всех частях тела.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Биопсия – взятие небольшого количества тканей для исследования свойств их клеток. На сегодняшний день этот метод является единственным способом, позволяющим безошибочно устанавливать диагноз. Образцы забираются из лимфатических узлов, костного мозга или других структур, передаются в лабораторию и тщательно изучаются.</span></li>\r\n</ul>\r\n<p> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Для взрослых и детей используются две основные методики лечения – химиотерапия различными препаратами (блеомицин, циклофосфамид, преднизолон, дакабразин и др.) и лучевая терапия, а также их комбинации. Иногда химиотерапия назначается в сочетании с пересадкой костного мозга. Возраст пациента не является определяющим фактором, большее значение имеют данные лабораторных исследований, тип опухоли, стадия и скорость прогрессирования.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Комбинирование химиопрепаратов и лучевой терапии считается одним из самых прогрессивных и эффективных методов, поскольку позволяет добиться длительной многолетней ремиссии у более чем половины пациентов.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Методов профилактики лимфомы в настоящее время не существует, поскольку до конца не изучены этиологические факторы, ведущие к развитию заболевания.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Признаки заболевания есть не у всех пациентов – люди с подобным диагнозом могут прекрасно себя чувствовать и не иметь никаких проблем со здоровьем. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Со временем, по мере развития лимфомы, нередко появляются следующие симптомы:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Самый частый из них – это опухоль или шишка на шее, подмышкой или в паху, которая представляет из себя увеличенный лимфатический узел</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Лимфатические узлы – это небольшие органы размером с фасоль, выполняющие роль фильтров, задерживающих и уничтожающих вредные для тела вещества. Они представляют из себя скопления лимфоцитов и других клеток иммунной системы, расположенных во всех частях организма, в том числе в шее, груди, животу, тазу и конечностях. Обычно она не доставляет никакого дискомфорта, но может стать болезненной после употребления алкоголя. Постепенно такое новообразование увеличивается, а рядом с ним или в других областях тела возникают новые припухлости.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">В большинстве случаев увеличение лимфоузлов вызвано не опасными опухолями, а обычными инфекциями. Они болят при прикосновении, но возвращаются к своему нормальному размеру после выздоровления.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Так называемые В-симптомы, являющиеся важной частью постановки диагноза и определения прогнозов пациента. Они включают лихорадку – повышение температуры до более чем 38°С на протяжении не менее чем трех дней подряд, сильную ночную потливость и снижение веса без всяких усилий минимум на 10% за последние 6 месяцев.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Кожный зуд.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Потеря аппетита.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">У некоторых людей единственным признаком лимфогранулематоза становится постоянная усталость.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Пораженные грудные лимфоузлы способны опухать, давить на трахею – дыхательное горло, вызывать боль, кашель или даже затруднение дыхания, особенно в положении лежа.</span></li>\r\n</ul>",
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}
]
}
