ВОзвращает список болезней. Можно фильтр/искать

search, age, gender, parent, symptoms, sort_name, sort_by, rand, branches
GET /disease/?format=api&ordering=-description&page=58
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

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            },
            "code": "K73",
            "name": "Хронический гепатит",
            "icd_name": "Хронический гепатит, не классифицированный в других рубриках",
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            "cause": [
                2,
                7,
                8,
                9,
                10
            ],
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            "lead": "Поражение гепатоцитов, вызванное различными причинами, характеризующееся гепатоцеллюлярным некрозом и воспалением, длящееся более 6 месяцев",
            "description": "",
            "etiology": "<p>Вирусы гепатитов В, С, Д, Е, аутоиммунные реакции, токсины и лекарственные средства.</p>",
            "pathogenesis": "<p>Под воздействием повреждающих агентов происходят цитолиз и некробиоз гепатоцитов. На фоне длительно существующего хронического гепатита часто развивается цирроз печени.</p>",
            "diagnostics": "<p>Проводится на основании жалоб, данных анамнеза, объективного осмотра, лабораторно-инструментальных методов исследования. Необходимо провести биохимическое исследование крови с исследованием уровня прямого и непрямого билирубина, АЛТ, холестерина, щелочной фосфатазы. Обязательными являются проведение тимоловой пробы, оценка сулемового титра. Проводят серологическое исследование крови, электронную иммунную микроскопию. В моче определяют уровень уробилиногена.</p>\r\n<p> </p>\r\n<p>Одним из важнейших методов диагностики является биопсия печени.</p>\r\n<p>Дифференциальная диагностика</p>\r\n<p>Проводится с циррозом печени, острыми гепатитами А, В, С, Д, Е, гастроэнтеритом, а также с надпеченочной или подпеченочной желтухой.</p>",
            "treatment": "<p>Необходимо соблюдение диеты. При хроническом вирусном гепатите назначают интерферон—2α.</p>",
            "prevention": "",
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            "published": 1,
            "parent": null,
            "block_rubric": 117,
            "standards": [
                4948
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        },
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                            "name": "Пахнет ацетоном изо рта"
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            "code": "A95",
            "name": "Желтая лихорадка",
            "icd_name": "Желтая лихорадка",
            "gender": 0,
            "age_min": 0,
            "age_max": 100,
            "cause": [
                2,
                6
            ],
            "periodicity": 1,
            "slug": "a95_zheltaya_lihoradka",
            "lead": "Инфекционная болезнь, относящаяся к группе геморрагических лихорадок, передающаяся комарами и характеризующаяся желтухой, сыпью, кровотечениями, поражением печени. Заболевание регистрируется в ряде тропических странах",
            "description": "",
            "etiology": "<p>Возбудителем является вирус желтой лихорадки (Flavivirus febricis), устойчивый при низкой температуре, быстро гибнет при температуре выше 60 °С, а также под воздействием обычных дезинфицирующих средств. Различают два эпидемиологических типа желтой лихорадки: эндемическую (джунглевую, или зоонозную) и эпидемическую (городскую, или антропонозную). В первом случае источником возбудителей инфекции являются обезьяны и, возможно, грызуны, переносчиком вируса – лесные комары рода Haemagogus и Aedes leucocelaenus (в Америке), A. africanus и A. simpsoni (в Африке). При эпидемической желтой лихорадке источником возбудителей инфекции служит человек, переносчиком возбудителей – комар A. aegipti.</p>",
            "pathogenesis": "",
            "diagnostics": "<p>Диагноз сложно поставить на ранних стадиях инфекции. Необходимо использовать серологические тесты.</p>",
            "treatment": "<p>Лечение патогенетическое и симптоматическое. Специфических методов терапии нет. Летальность в зависимости от характера эпидемии колеблется от 1 до 25 %. В целях профилактики заболеваний лиц, выезжающих за рубеж в местности, неблагополучные по желтой лихорадке, вакцинируют. Во время пребывания на такой территории используют средства защиты от комаров – репелленты, защитные сетки.</p>",
            "prevention": "<p>Вакцинация — основной способ профилактики желтой лихорадки. В районах с высоким риском заболевания, для которых характерен слабый охват прививками, важнейшим условием предотвращения эпидемий является своевременное выявление и подавление вспышек болезни посредством массовой вакцинации населения. При этом, чтобы не допустить дальнейшего распространения заболевания в регионе, где зафиксирована вспышка, важно обеспечить большой охват иммунизацией подверженного риску населения (не менее 80%).</p>\r\n<full></full>\r\n<p>Для предотвращения вспышек применяется ряд стратегий: плановая иммунизация детей грудного возраста; проведение кампаний по массовой вакцинации для расширения охвата в странах, где существует риск вспышек болезни; вакцинация лиц, совершающих поездки в районы, эндемичные по желтой лихорадке.</p>\r\n<p>Вакцина от желтой лихорадки является безопасной и недорогостоящей. При этом одна доза вакцины достаточна для формирования пожизненного иммунитета без необходимости ревакцинации.</p>\r\n<p>В редких случаях сообщается о серьезных побочных эффектах вакцины против желтой лихорадки. Показатель частоты таких «неблагоприятных проявлений после иммунизации» (НППИ), когда после введения вакцины наблюдаются поражения печени, почек и нервной системы, что делает необходимой госпитализацию, составляет от 0,4 до 0,8 на 100 000 вакцинированных.</p>\r\n<p>Уровень риска выше у лиц старше 60 лет, пациентов с тяжелым иммунодефицитом, связанным с симптоматическим ВИЧ/СПИДом или другими факторами, а также лиц с нарушениями вилочковой железы. Вакцинацию людей старше 60 лет следует проводить после тщательной оценки потенциального риска и пользы иммунизации.</p>\r\n<p>Как правило, к числу лиц, не подлежащих вакцинации, относятся:</p>\r\n<ul class=\"disc\">\r\n<li>дети грудного возраста младше 9 месяцев (кроме случаев эпидемии, когда вакцинации подлежат дети грудного возраста от 6 до 9 месяцев в районах с высоким риском инфекции);</li>\r\n<li>беременные женщины (кроме случаев вспышки желтой лихорадки и высокого риска инфекции);</li>\r\n<li>лица с тяжелыми формами аллергии на яичный белок;</li>\r\n<li>лица с тяжелым иммунодефицитом, связанным с симптоматическим ВИЧ/СПИДом или другими факторами, а также лица с нарушениями вилочковой железы.</li>\r\n</ul>\r\n<p>В соответствии с Международными медико-санитарными правилами (ММСП) страны имеют право требовать от лиц, совершающих поездки, представить свидетельство о вакцинации против желтой лихорадки. При наличии медицинских противопоказаний к вакцинации необходимо предоставить соответствующую справку от компетентных органов. ММСП — это юридически обязательный механизм, предназначенный для предотвращения распространения инфекционных заболеваний и других источников угрозы для здоровья населения. Применение к лицам, совершающим поездки, требования по предоставлению свидетельства о вакцинации оставлено на усмотрение каждому государству-участнику и в настоящее время практикуется не всеми странами.</p>",
            "clinical_picture": "<p>Инкубационный период продолжается 3–6 дней. Болезнь начинается внезапно, температура тела поднимается до 39–40°, отмечаются: резкая \"></a>, \"></a>, боли в пояснице и конечностях,  с ознобом\">Озноб</a>\"> с ознобом\">озноб</a></a>, \"></a>, иногда \">Рвота</a>\">\">рвота</a></a>, . Лицо, шея, верхняя часть туловища гиперемированы, веки отечны, лицо одутловато. Затем развиваются  десен, , отмечается примесь крови в кале. На 4–5-й день болезни наступает ремиссия, длящаяся от нескольких часов до одних суток. В легких случаях за этим наступает выздоровление. Чаще состояние больного вновь резко ухудшается, развиваются: интоксикация, тяжелый геморрагический синдром – кровотечения из носа, желудка, кишечника, матки, появляется геморрагическая .</p>",
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            "image_alt": "Желтая лихорадка",
            "standard_type": 3,
            "danger": 81,
            "published": 1,
            "parent": null,
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        {
            "id": 6050,
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                    "id": 2848,
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                        {
                            "name": "мышечная боль"
                        },
                        {
                            "name": "боль в мышцах"
                        },
                        {
                            "name": "мышцы болят"
                        },
                        {
                            "name": "Миалгия"
                        },
                        {
                            "name": "ломота"
                        },
                        {
                            "name": "боль в мышцах рук"
                        },
                        {
                            "name": "боль в мышцах ног"
                        },
                        {
                            "name": "боль в мышцах после тренировки"
                        },
                        {
                            "name": "боль в мышцах спины"
                        },
                        {
                            "name": "боль икроножная"
                        }
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                            "x": 265,
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                            "r": 0
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                    "lead": "Воспаление лимфатических узлов свидетельствует о проблемах в зоне, которую \"обслуживает\" узел. Чаще всего увеличение лимфоузла связано инфекцией, реже оно является следствием опухолевого поражения",
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                        {
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                        },
                        {
                            "name": "Боль выше пупка"
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                        {
                            "name": "Боль ниже пупка"
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                        {
                            "name": "Острые боли в животе"
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                        {
                            "name": "Боль в области живота "
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                        {
                            "name": "Боль в области пупка"
                        },
                        {
                            "name": "Боль в правой жасти живота"
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                        {
                            "name": "Пупок тянет"
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                        {
                            "name": "Болит пупок"
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                        {
                            "name": "Болит живот снизу"
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                        {
                            "name": "Болит живот сверху"
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                        {
                            "name": "Боль в правой части живота"
                        },
                        {
                            "name": "Боль в животе у ребенка"
                        },
                        {
                            "name": "У ребенка болит живот"
                        },
                        {
                            "name": "Острая боль в животе"
                        },
                        {
                            "name": "Резь в животе"
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                        {
                            "name": "Боль под ложечкой"
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                        {
                            "name": "Боль после еды"
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                        {
                            "name": "Боль при аппендеците"
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                    "lead": "Боль в животе может быть признаком многих  заболеваний,  если боль появилась внезапно или продолжительная, обратитесь к врачу",
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                            "name": "Пот"
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                            "name": "Повышенное потоотделение"
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                        {
                            "name": "Потливость ладоней"
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                        {
                            "name": "Ночная потливость"
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                        {
                            "name": "Сильно потею"
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                    "age_min": 0,
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                    "slug": "potlivost",
                    "lead": "Потливость общая или локализованная может быть достаточно неприятным симптомом,  проконсультируйтесь со специалистом",
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                            "name": "Жар"
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                            "name": "Озноб"
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            "code": "A44",
            "name": "Бартонеллез",
            "icd_name": "Бартонеллез",
            "gender": 0,
            "age_min": 0,
            "age_max": 100,
            "cause": [
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            "periodicity": 1,
            "slug": "a44_bartonellez",
            "lead": "группа заболеваний, вызываемых бактериями из рода Bartonella, протекающих с преимущественным поражением эндотелиальных клеток и эритроцитов",
            "description": "",
            "etiology": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В организм человека бактерии проникают через укусы комаров, клещей, вшей или микроповреждения кожи. Резервуаром инфекции является человек, больной острыми формами, либо бессимптомный бактерионоситель. Частота бессимптомной бактериемии у носителей инфекции достигает 50%. Восприимчивость к бартонеллезу у жителей эндемичных районов высокая. Антисанитарные условия, скученность людей способствуют увеличению частоты инфицирования.</span></p>",
            "pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В месте проникновения возбудителя образуется первичный аффект &ndash; папула, везикула или пустула. Далее с током лимфы возбудитель проникает в лимфатические узлы &ndash; развивается лимфаденопатия. При преодолении лимфатического барьера патоген поступает в кровь &ndash; наступает бактериемия. Наиболее чувствительными к бартонеллам являются эритроциты и эндотелиальные клетки сосудов, костный мозг, клапаны сердца. Активное размножение возбудителя в эритроцитах и их разрушение вызывает развитие гемолитической анемии.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При острых процессах в клетках эндотелия преобладают некротические изменения, стенка сосудов инфильтрируется лейкоцитами и макрофагами с образованием гранулем, явления пролиферации выражены незначительно. В слизистых оболочках, коже появляются мелкие кровоизлияния. Для хронического течения бартонеллеза характерно образование новых мелких сосудов с формированием ангиоэндотелиом. При состоятельности системы иммунитета образуются антитела с последующей элиминацией возбудителя. В случае иммунодефицитных состояний происходит хронизация процесса с длительной персистенцией бартонелл в крови. Отсутствие лечения в такой ситуации может привести к летальному исходу. У выздоровевших пациентов формируется стойкий иммунитет.</span></p>",
            "diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При подозрении на бартонеллез необходима консультация терапевта, инфекциониста, дерматолога, в случае поражения нервной системы &ndash; невролога, развития гнойных осложнений &ndash; хирурга. Во время физикального обследования отмечается бледность, на коже &ndash; первичный аффект с регионарной лимфаденопатией, при пальпации &ndash; увеличенная печень, селезенка. В диагностике используются следующие лабораторно-инструментальные методы:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Исследования крови. В общем и биохимическом анализах крови наблюдается гемолитическая макроцитарная нормо- или гипохромная анемия, маркеры воспаления (СРБ, прокальцитонин, повышение уровня глобулинов), ускорение СОЭ. Лейкоцитоза может не быть, при тромбозе отмечается снижение показателей фибриногена, повышение уровня Д-димеров.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Прямое обнаружение возбудителя. При микроскопии мазков крови, окрашенных по Романовскому&ndash;Гимзе, патогенные микроорганизмы выявляются снаружи и внутри кровяных телец. Также в качестве препарата может использоваться биопсийный материал из лимфатических узлов или элементов сыпи. По посеву крови предварительно судить о наличии и степени бактериемии возможно через 3 дня, окончательно &ndash; через 7-10 дней. ДНК возбудителя идентифицируют методом ПЦР.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Серологические методы диагностики. Проводят определение антител (IgM и IgG) в сыворотке крови пациента методом реакции гемагглютинации, связывания комплимента, непрямой иммунофлюоресценции, иммуноферментного анализа. Для обнаружения антигенов бартонелл выполняют иммуноблоттинг, вестерн-блоттинг.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">УЗИ органов брюшной полости. УЗИ ОБП не является специфическим методом выявления бартонеллеза. Во время процедуры определяется увеличение печени, селезенки, внутрибрюшных лимфоузлов. Возможно выявление в паренхиматозных органах полостей, заполненных жидкостью, очагов пролиферации. Подобная картина может напоминать множество других заболеваний.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">&nbsp;</span></p>",
            "treatment": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение осуществляется в инфекционном стационаре. Необходимо соблюдение постельного режима. Проводится этиотропная терапия антибактериальными препаратами. Поскольку возможно последующее вторичное присоединение сальмонеллеза, рационально использовать ципрофлоксацин или хлорамфинекол в сочетании с &beta;-лактамным антибиотиком. Препаратами резерва являются макролиды, тетрациклины, рифампицин. При необходимости назначается симптоматическое лечение (дезинтоксикационная терапия, жаропонижающие препараты, гепатопротекторы, переливание эритроцитарной массы). На инфицированные кожные элементы после промывания антисептиками накладывают повязки с антибактериальными мазями.</span></p>",
            "prevention": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Специфическая профилактика не разработана, но вакцина, не предохраняя от заболевания, значительно облегчает клиническое течение болезни. Основная мера профилактики бартонеллеза &mdash; борьба с переносчиками болезни (москитами) и предохранение от их укусов в местностях, эндемичных для этого заболевания.</span></p>",
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