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"code": "B79",
"name": "Трихуроз",
"icd_name": "Трихуроз",
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"lead": "Заболевание, вызываемое паразитом Trichocephalus Trichiurus .",
"description": "Инфекционное заразное заболевание.",
"etiology": "<p>Власоглав является желудочно-кишечной нематодой из семейства Trichuridae, род Trichuris. Взрослые особи Т. Trichiurus выглядят как длинные черви, имеющие длинный тонкий передний конец, который расположен на слизистой оболочке захваченного органа (кишечника), и толстый конец, уходящий в просвет кишечника.Т. trichiurus паразитирует только у человека, который заражается при проглатывании инвазионных яиц, созревших в почве. В тонком кишечнике оболочка яйца разрушается, из него выходит личинка, которая с помощью стилета проникает в глубокий слой слизистой, развивается там в течение 3-10 суток, после чего выходит в просвет, спускается в слепую кишку, где примерно через 1,5 месяца достигает половозрелого состояния. <br /><br />Длительность жизни паразита в организме человека 5-7 лет. </p>",
"pathogenesis": "<p>Внедряясь в стенку кишки, власоглав своим тонким волосовидным головным концом как бы «прошивает» слизистую оболочку, проникая иногда до подслизистого и мышечного слоев. В местах локализации паразита вокруг мест внедрения головного конца на слизистой оболочке возникают инфильтраты, мелкие кровоизлияния, отеки, эрозии. Изменения и травматизация стенки кишки, которые зависят от интенсивности инвазии, способствуют проникновению микробной флоры. И. И. Мечников еще в 1901 г. указал на значительную роль власоглава в развитии аппендицита и тифлита. <br /><br />Определенное значение в патогенезе трихоцефалеза имеет сенсибилизирующее действие продуктов обмена на организм. Надо полагать, что именно этим усугубляется влияние бактериальной флоры на слизистую толстой кишки, что клинически проявляется склонностью таких больных к диареям, а также к неврологическим расстройствам. <br /><br />Важную роль в патогенезе трихоцефалеза имеют висцеральные рефлексы, которые связывают илеоцекальную область (место локализации власоглавов) с другими участками кишечника. Раздражение нервных окончаний илеоцекальной области влечет за собой нарушение секреторной и моторной функции желудка. Этим объясняются частые нарушения ппи трихоцефалезе секреции желудка, возникновение болей в эпигастральной области, симулирующих язвенную болезнь желудка и двенадцатиперстной кишки. </p>",
"diagnostics": "<p>Диагноз устанавливается на основании обнаружения в кале яиц при просмотре под бинокуляром больших мазков, а также методами флотации с исследованием поверхностной пленки под бинокуляром непосредственно в стаканчике или после снятия ее предметным стеклом. В виду того, что у значительной части зараженных интенсивность инвазии бывает слабая, яиц в кале часто бывает мало и их трудно обнаружить. Поэтому необходимы тщательные и повторные исследования. Учет результатов лечения проводят путем контрольного исследования кала через 15-20 дней после дегельминтизации.</p>",
"treatment": "<p>Лечению от трихоцефалеза подвергают только инвазированных; у остальных членов семьи проводят трехкратное копроовоскопическое обследование. Рекомендуют дифезил, бемосат, вермокс (по общепринятым схемам). Для определения эффективности лечения клинико-диагностическая лаборатория лечебного учреждения, выявившего инвазированного и лечившего его, проводит трехкратное обследование (с интервалом 15-20 дней). Диспансеризация инвазированного и его семьи осуществляется в течение 2 лет после момента вылечивания. За это время весной и осенью всех членов семьи обследуют на гельминтозы, а санитарно-эпидемиологическая служба в эти же сроки проводит выборочное эпидемиологическое обследование микроочагов с гельминтологическим исследованием элементов внешней среды.</p>\r\n<full></full>\r\n<p><br /><br />Микроочаг снимают с учета, если в течение 2 лет с момента излечения инвазированного в нем не было зарегистрировано ни одного случая трихоцефалеза, ложный микроочаг - после трехкратного отрицательного результата обследования по методу Калантарян с момента завершения лечения. В случае установления постоянной связи между ложным и истинным микроочагами оздоровление проводят в обоих одновременно, а срок диспансеризации в них в этом случае составляет 2 года.</p>",
"prevention": "<p>Важнейшее значение имеют мероприятия, направленные на охрану почвы от фекальных загрязнений и на повышение санитарной грамотности населения.</p>",
"clinical_picture": "<p>Клиническая картина трихоцефалеза разнообразна и зависит от интенсивности инвазии, реактивности организма и наличия сопутствующих заболеваний. <br /><br />При неинтенсивной инвазии трихоцефалез протекает субклинически. При клинически выраженных формах обычно наблюдаются симптомы патологии желудочно-кишечного тракта и нервной системы, однако патология, характерная только для этой инвазии, при трихоцефалезе отсутствует.</p>\r\n<full></full>\r\n<p><br /><br />Нарушения деятельности желудочно-кишечного тракта проявляются в снижении аппетита, тошноте, рвоте, слюнотечении. Больные отмечают боли в правой илеоцекальной области, напоминающие боли при аппендиците, боли схваткообразного характера в области эпигастрия, симулирующие клинику гастрита, язвенной болезни. Иногда при трихоцефалезе у инвазированного развивается картина колита с поносами или запорами, реже с наличием в фекалиях видимой слизи и крови. Со сторон нервной системы при трихоцефалезе могут иметь место жалобы на головную боль, головокружение, раздражительность, плохой сон, реже - обморочные состояния, судорожные припадки.</p>",
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"lead": "одна из форм аутодеструктивного поведения, сопровождающаяся периодически повторяющимися эпизодами выдергивания собственных волос",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Трихотилломания – это хроническая травматическая алопеция, к формированию которой приводит психическое расстройство, характеризующееся регулярным вырыванием собственных волос из кожи головы, бровей, ресниц, лобка и других участков тела.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Стремление выдергивать волосы формируется при воздействии внешних и внутренних факторов. К ним относятся:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Психические заболевания. Трихотилломания может развиться на фоне депрессии, невроза навязчивых состояний, биполярного аффективного расстройства, шизофрении, деменции, умственной отсталости, органической психопатии.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Психологические особенности. У мнительных, впечатлительных, тревожных, испытывающих вину людей необходимость снять эмоциональное напряжение реализуется через выдирание волос.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Стиль воспитания. Высокие требования к поведению ребенка, школьной успеваемости, тотальный контроль, гиперопека, частые укоры, критика способствуют формированию чувства вины, заниженной самооценки. Аутодепиляция становится средством отвлечения, самонаказания.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Стрессы. Интенсивные травмирующие переживания способны стать пусковым механизмом для трихотилломании. Данное расстройство часто дебютирует после смерти близкого человека, смены школы, потери работы, переезда, развода, акта насилия.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В патогенезе трихотилломании рассматриваются психологический и физиологический аспекты. Поверхность кожи хорошо иннервируется густой сетью афферентных и эфферентных нервных волокон. Благодаря высокой чувствительности она становится фокусом снятия напряжения, установления контроля над эмоциями. Выдергивая волосы, человек испытывает физическую боль, которая переключает внимание с напряжения, тревожности, подавленности, снижает чувство вины, так как является результатом самонаказания. Доставляя боль самому себе, больной подсознательно надеется, что требования, упреки, критика, обвинения окружающих станут менее выраженными. С другой стороны, в стрессовых, психотравмирующих ситуациях собственное тело остается единственной сферой, поддающейся контролю. Выполняя аутоагрессивные действия, люди реализуют невыраженный страх, гнев, злость.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основу диагностики трихотилломании составляет осмотр, сбор анамнеза. Психиатрическая оценка расстройства выполняется методом клинической беседы, наблюдения за поведением пациента. Диагностическими критериями являются:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Периодичность. Выдергивание производится неоднократно, систематически, сопровождается потерей волос.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Сопротивление. Пациент предпринимает попытки прекращения действий. Критерий актуален для подростков, взрослых.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дистресс. Аутоэпиляция сопровождается проблемами социальной адаптации, негативными переживаниями.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отсутствие иных заболеваний. Удаление волос не может быть объяснено другим соматическим заболеванием или дисморфофобией (аутоэпиляция для улучшения внешности).</span></li>\r\n</ul>\r\n<p><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Психиатрическое обследование дополняется анкетированием. Используется шкала аутоэкстракции волос, шкала тяжести трихотилломании. С целью определения психотерапевтических целей проводится полное исследование эмоционально-личностной сферы, внутрисемейных отношен</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дерматологическое обследование включает осмотр и трихоскопию – компьютерный метод диагностики состояния волос. Врач-дерматолог выявляет следующие признаки:</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Очаги облысения. На бровях, волосистых участках тела, головы обнаруживаются области поредения волос, облысения. Очаги различной формы, множественные, единичные.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Состояние кожи. В местах облысения кожные покровы нормальные либо огрубевшие, без шелушения. Возможны струпья, гнойные пузырьковые образования, эритемы, отечность.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Состояние волос. Определяется четкая обозначенность устьев волосяных фолликулов. Волосы различной длины, обломанные, имеют вид черных точек, щетины.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение расстройства проводится дерматологом, психиатром и психотерапевтом. Оно состоит из следующих компонентов:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Когнитивно-бихевиоральная психотерапия. Цель данного метода – замещение патологического поведенческого паттерна адаптивным. На начальном этапе происходит когнитивная переработка: осознавание позывов, влечений к выполнению действия, распознавание провоцирующих ситуаций, сопутствующих эмоций. Затем осваиваются техники релаксации, разрабатываются стратегии альтернативных способов поведения.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Психофармакотерапия. Данные об эффективности применения препаратов спорны. Врач-психиатр подбирает схему лечения, учитывая клиническую картину расстройства, наличие сопутствующих психических заболеваний. Могут быть назначены антидепрессанты СИОЗС, антагонисты опиоидных рецепторов, препараты лития, анксиолитики, стимуляторы ЦНС, нейролептики.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Местная терапия. Дерматолог составляет план симптоматического лечения. Назначаются антисептики, местные антибиотики, противовоспалительные, противогрибковые средства (при вторичном инфицировании), стимуляторы роста волос.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"prevention": "<p><span id=\"docs-internal-guid-69d00b47-7fff-1c21-f466-83963a72970c\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Профилактика в детском возрасте основана на правильном подборе методов воспитания: детям, склонным к тревожности, нельзя предъявлять жестких требований, критиковать, обвинять, сравнивать с другими. Важно поддерживать их, вселять уверенность, обучать продуктивным способам совладания со стрессом. Для людей всех возрастов рекомендованы действия, позволяющие снизить эмоциональное и физическое напряжение – водные процедуры, занятия спортом, творчеством.</span></span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дети дошкольного возраста выполняют аутодепиляцию неосознанно. Малыши выдергивают волосы при просмотре мультфильмов, во время увлекательной игры, творческих занятий, а также в ситуациях стресса – при внезапном испуге, ссоре родителей, выслушивании упреков, критических замечаний. Местами поражения являются лобно-теменные области, брови. Около 10% детей съедают вырванные волосы. Обнаружить действия ребенка нетрудно – он их не скрывает, не маскирует результат.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Школьники, подростки вырывают волосы, осознавая процесс либо результат. Они могут критически относится к расстройству, понимают, что их действия являются ненормальными. Осуществляются попытки контролировать поведение. Вырывание волос производится автоматически пальцами при выполнении рутинных действий – при чтении, письме, разговоре по телефону, просмотре фильмов, телепередач. Сознательно аутодепиляция выполняется при повышенном эмоциональном напряжении: подросток уединяется, подготавливает инструменты (пинцет, салфетки). Распространенные области – волосистая часть головы, брови, ресницы, лобок. Очаги поредения, облысения маскируются подростками: парни, девушки неожиданно начинают носить аксессуары – платки, шарфы, капюшоны, шляпы, шапки. Иногда родители случайно обнаруживают очаг облысения, отсутствие фрагмента брови.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Клиническая картина трихотилломании у взрослых схожа с таковой у подростков. Преобладает осознанное вырывание волос, попытки противостоять навязчивым действиям. Женщины скрывают последствия: предпочитают одежду с длинными рукавами, темные очки, делают накладные ресницы, татуаж бровей. Мужчины отрицают наличие расстройства, объясняя облысение гормональными причинами.</span></p>",
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"code": "A59",
"name": "Трихомониаз",
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"lead": "Нарушение здоровья, относящееся к группе инфекции, передающиеся преимущественно половым путем",
"description": "Трихомониаз – это инфекционное заболевание мочеполовой системы, которое вызывается влагалищной трихомонадой. ",
"etiology": "<p>Возбудителем урогенитального трихомониаза является влагалищная трихомонада, которая относится к простейшим одноклеточным организмам. Трихомонады не устойчивы во внешней среде и при высушивании быстро погибают, но возможно сохранение их активности во влажной сфере (белье, мочалки, полотенца). </p>\r\n<p>Передается трихомониаз половым путем, хотя и не исключено и внеполовое заражение: вертикальный путь передачи возбудителя во время родов, при прохождении плода через инфицированные родовые пути. Бытовой путь передачи влагалищной трихомонады в настоящее время подвергается сомнениям. Многие авторы утверждают, что возможно заражение через полотенца, купальники и прочее. </p>\r\n<p>Факторы, способствующие развитию урогенитального трихомониаза: </p>\r\n<ul>\r\n<li>расстройства эндокринной системы; </li>\r\n<li>нарушения обмена веществ; </li>\r\n<li>гиповитаминоз; </li>\r\n<li>бактериальное загрязнение влагалища, сопровождающееся изменением его кислотности; </li>\r\n<li>менструация и послеменструальный период. </li>\r\n</ul>",
"pathogenesis": "<p>Трихомонады закрепляются в клетках слизистой оболочки мочеполового тракта и вызывают там воспалительный процесс. Продукты жизнедеятельности трихомонад отравляют организм человека, снижают его иммунитет. </p>\r\n<p>Трихомонады могут обитать в половых органах и даже в кровяном русле, куда проникают через лимфатические пути, межклеточные пространства с помощью фермента - гиалуронидазы. Трихомонады чрезвычайно приспособлены к существованию в организме человека: могут менять форму, маскироваться под клетки плазмы крови (тромбоциты, лимфоциты) - что затрудняет диагностику трихомониаза; «цеплять» на себя других микробов и этим способом уклоняться от иммунной атаки организма. </p>\r\n<p>Попав на слизистую оболочку влагалища, трихомонады выделяют специальные вещества, позволяющие прочно прикрепиться к её стенкам. Кроме того вагинальная трихомонада обладает свойством вырабатывать специальные ферменты, расщепляющие поверхностно расположенные клетки слизистой оболочки влагалища. В ответ на агрессивное воздействие трихомонад, в слизистой влагалища возникают воспалительные процессы, которые выражаются следующими изменениями: </p>\r\n<ul>\r\n<li>Резкое покраснение и отек слизистой </li>\r\n<li>Отслоение поверхностного слоя клеток </li>\r\n<li>Мелкоточечные кровоизлияния </li>\r\n<li>Повышение местной температуры </li>\r\n</ul>",
"diagnostics": "<p>На основании жалоб больных и осмотра можно заподозрить наличие трихомонад. При осмотре у больных трихомониазом женщин наблюдаются признаки воспаления — отек и гиперемия вульвы и влагалища. При проведении кольпоскопии может наблюдаться симптом «земляничного цервикса»: покраснение слизистой с точечными и очаговыми кровоизлияниями на шейке матки. Отмечается дисплазия эпителия, иногда возможно появление атипичных эпителиальных клеток. </p>\r\n<p>Из лабораторных методов диагностики применяют: </p>\r\n<ul>\r\n<li>микроскопическое исследование нативных мазков из влагалища, уретры и шейки матки (достоверен только при быстрой микроскопии свежевзятых мазков); </li>\r\n<li>микроскопическое исследование окрашенных мазков по Грамму; </li>\r\n<li>культуральный метод (посев слизи и содержимого уретры на питательные среды, занимает от 4 до 7 дней); </li>\r\n<li>ПЦР (полимеразная цепная реакция) – выделение ДНК трихомонад из отделяемого уретры или влагалища. </li>\r\n</ul>",
"treatment": "<p>Современные методы лечения больных трихомониазом основаны на использовании специфических противотрихомонадных средств. Лечению подлежат все больные, у которых обнаружены влагалищные трихомонады, независимо от наличия или отсутствия у них воспалительных явлений в половом аппарате, а также больные с воспалительными процессами, у которых при обследовании трихомонады не обнаружены, но простейшие обнаружены у половых контактов или источников заражения. </p>\r\n<p>При лечении трихомониаза назначают антипаразитарную терапию: используют препараты группы 5-нитроимидазолов. К ним относятся тинидазол, метронидазол, орнидазол, ниморазол, тернидазол. </p>\r\n<p>Параллельно с лечением соблюдают гигиенические правила по уходу за мочеполовыми органами: </p>\r\n<ul>\r\n<li>Ежедневное подмывание половых органов с использованием антисептических средств (слабый раствор перманганата калия, раствор фурацилина) или детергентов, то есть обычного туалетного мыла. </li>\r\n<li>Индивидуальное использование туалетных принадлежностей (мыла, мочалок, полотенец). </li>\r\n<li>Ежедневная смена нижнего белья.</li>\r\n</ul>",
"prevention": "<p>Основной мерой профилактики трихомониаза является отказ от беспорядочной половой жизни и наличие только одного сексуального партнера, в котором есть полная уверенность. Также к мерам профилактики можно отнести следующее: </p>\r\n<ul>\r\n<li>Обязательное использование презервативов во время половых отношений. </li>\r\n<li>Строгое соблюдение норм личной гигиены. </li>\r\n<li>Регулярная сдача анализов и обследование у врача. </li>\r\n</ul>",
"clinical_picture": "<p>Симптомы заболевания у женщин: </p>\r\n<ul>\r\n<li>обильные пенистые или жидкие выделения желтоватого, зеленоватого оттенка с неприятным «рыбным» запахом; </li>\r\n<li>зуд, жжение и гиперемия наружных половых органов; </li>\r\n<li>боль при мочеиспускании; </li>\r\n<li>боль при половых контактах. </li>\r\n<li>слизистая оболочка влагалища резко гиперемирована, легко кровоточит, покрыта гнойными выделениями </li>\r\n</ul>\r\n<p>Симптомы заболевания у мужчин: </p>\r\n<ul>\r\n<li>выделения из мочеиспускательного канала; </li>\r\n<li>боль при мочеиспускании; </li>\r\n<li>при поражении предстательной железы — симптомы простатита; </li>\r\n<li>в редких случаях возможно выделение крови из мочеиспускательного канала. </li>\r\n</ul>",
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"description": "<p><span id=\"docs-internal-guid-18192d37-7fff-f7aa-19fb-363e00ccff7e\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Трихинеллез ― это поражение внутренних органов и центральной нервной системы трихинеллой, круглыми червями, паразитирующими в тонкой кишке.</span></span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заражение людей происходит при употреблении в пищу сырого или недостаточно проваренного мяса пораженных трихинеллезом животных, чаще всего мяса, сала, окорока, бекона, корейки, грудинки, колбасы, изготовленных из инвазированной свинины, а также пораженного трихинеллами мяса диких животных (медведя, дикого кабана, барсука). Для того чтобы получить тяжелое заболевание, достаточно съесть 10-15 г трихинеллезного мяса.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заболеваемость трихинеллезом обычно носит групповой характер. Заболевают члены одной семьи, лица, участвующие в одном праздничном застолье, охотничьей трапезе, использовавшие в питание мясо одного и того же трихинеллезного животного, не прошедшего предварительного ветеринарного контроля.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Домашние свиньи заражаются трихинеллами при поедании не обезвреженных мясных отходов, тушек диких животных, грызунов. Дикие животные - при хищничестве и через падаль.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Трихинеллы отличаются большой устойчивостью к различным методам их обеззараживания. Не убивает их копчение и засолка. Остаются они живыми даже в жареном и варёном мясе. Известны случаи заражения людей при употреблении сала (с прожилками мяса), ветчины, варёной колбасы, сосисок, пельменей, шашлыков.</span></p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Люди заражаются при употреблении в пищу сырого, непрожаренного или термически недостаточно обработанного мяса зараженных животных, обычно свиней, дикого кабана или медведя. В тонкой кишке личинки покидают капсулы и проникают в подслизистый слой; через 6–8 дней они превращаются во взрослых самцов и самок. Особи женского пола приблизительно 2,2 мм длиной, а особи мужского пола приблизительно 1,2 мм длиной.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Зрелые особи женского пола продуцируют живых личинок в течение 4–6 недель, а затем умирают или выводятся. Личинки мигрируют через кровоток и лимфатическую систему, откуда попадают в поперечно-полосатую мускулатуру, где в конечном счёте и живут. Личинки полностью инкапсулируются в течение 1–2 месяцев и остаются жизнеспособными в течение нескольких лет как внутриклеточные паразиты. Мертвые личинки в конечном счете рассасываются или петрифицируются.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Наиболее распространенными диагностическими методами подтверждения трихинеллеза являются следующие инструментальные и лабораторные исследования:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Физикальное обследование. При объективном осмотре обращают на себя внимание отеки лица, параорбитальной клетчатки, гиперемия конъюнктив, макулопапулезная сыпь на теле. Пациенты с трудом совершают произвольные движения, иногда образуются мышечные контрактуры. В легких при аускультации могут выслушиваться сухие диффузные хрипы. У половины больных наблюдается гепатомегалия.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лабораторные исследования. Одним из ведущих признаков трихинеллеза является лейкоцитоз и эозинофилия (20-60%) в общем анализе крови с максимальными значениями на 2-4 неделе болезни. Биохимические параметры отличает повышение активности АЛТ и АСТ, гипергаммаглобулинемия, снижение общего белка и электролитов гипоальбуминемия. В мокроте могут быть обнаружены кристаллы Шарко-Лейдена.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Выявление инфекционных агентов. Серологическая диагностика (ИФА) становится информативной с 3-й недели болезни, требуется проведение исследований в парных сыворотках с интервалом 10-14 дней. Диагностическим титром считается 1:100 и более. В редких случаях не ранее 9-10 суток заболевания производят микроскопию биоптатов мышечной ткани, в которых выявляются возбудители.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инструментальные методики. Ультразвуковое исследование суставов, мягких тканей и органов брюшной полости рекомендовано с целью дифференциальной диагностики. Проведение ЭКГ, ЭХО-КС пациентам с трихинеллезом необходимо для исключения миокардита. Рентгенография органов грудной клетки назначается по показаниям, в случае поражения легких могут определяться «летучие» инфильтраты.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пациенты со среднетяжелой и тяжелой формами болезни нуждаются в стационарном лечении. При нарастании признаков дыхательной недостаточности, манифестации миокардита больные находятся в отделении интенсивной терапии. Постельный режим рекомендован до 3-4 дней отсутствия повышенной температуры тела при купированном болевом синдроме. Питание пациентов с трихинеллезом не имеет специфических ограничений, рекомендуется придерживаться щадящей диеты с достаточным количеством белка. Водный режим подлежит коррекции, связанной с отечным синдромом, требуется исключение алкоголя, газированных напитков, кофе, чая.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В схему терапии трихинеллеза обязательно включают этиотропные препараты (альбендазол, мебендазол, тиабендазол). Симптоматическое лечение направлено на купирование отечного (фуросемид, дихлотиазид), и аллергического (индометацин, дезлоратадин) компонентов заболевания, дезинтоксикацию (хлосоль, глюкозо-солевые растворы), десенсибилизацию (хлорид, глюконат кальция). По показаниям используются гормональные средства (преднизолон, дексаметазон), осуществляется коррекция гипопротеинемии (альбумин, свежезамороженная плазма). Исследуется возможность применения ритуксимаба как альтернативы глюкокортикостероидам.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В целях профилактики придерживайтесь следующих простых правил:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Проводить визуальный осмотр мяса.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Никогда не употребляйте сырое или недоготовленное мясо.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Откажитесь от употребления мяса диких животных и птиц.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">По возможности откажитесь от употребления сала, шпика, фарша, домашних колбас и бекона.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Выбирайте мясные продукты только в проверенных магазинах, но даже в этом случае подвергайте их тщательной термической обработке.</span></li>\r\n<li>Всегда хорошо промывайте ножи и разделочные доски с посудой, которые соприкасались с сырым мясом.</li>\r\n</ul>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Симптоматика болезни выглядит следующим образом:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Сразу после заражения трихинеллезом у человека возникает небольшая боль в кишечнике, которая сопровождается диареей несколько дней. Но при приеме лекарственных препаратов, все нарушения в работе организма прекращаются и человек попросту забывает о проблеме.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Через 2-3 недели после заражения проявляются общие симптомы болезни: головная боль, в конъюнктивных мешках возможно кровоизлияние, глаза принимают покрасневший вид, возможна слабая лихорадка. Часто у людей на какое-то время возникает светобоязнь, но она быстро проходит.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При сильных инфекциях, симптомы проявляют себя значительно ярче: возможно резкое повышение температуры до 40 градусов, появляется сильный кашель и боли в легких, нарушается слух и зрение, возможны проблемы с сердцем. Возможно развитие миокардита, шока, гепатита, пневмонии и других осложнений.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Однако у большинства людей тяжелые признаки трихинеллеза не проявляются, все проблемы исчезают через какое-то время, особенно если человек использует для лечения различные препараты, на что обычно уходит 2-3 месяца с появления первых проблем со здоровьем. Но далее начинают возникать боли в мышцах, так как личинки трихинелл попадают в мышечные ткани и образуют небольшие капсулы. Боль может появляться при глотании пищи или воды, что связано с увеличением шейных лимфоузлов и миндалин.</span></p>",
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