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"etiology": "<p>Причины острого эзофагиты: </p>\r\n<ul>\r\n<li>острые инфекционные процессы; </li>\r\n<li>физическое повреждение (ожог, травмирование при введении зонда, повреждение инородными телами); </li>\r\n<li>химический ожог; </li>\r\n<li>аллергическая реакция на пищевые продукты. </li>\r\n</ul>\r\n<p>Причины развития хронических эзофагитов: </p>\r\n<ul>\r\n<li>алиментарный эзофагит (употребление очень горячей, острой пищи, крепкого алкоголя); </li>\r\n<li>профессиональный эзофагит (работа, связанная с вдыханием паров едких химических веществ); </li>\r\n<li>застойный эзофагит (раздражение слизистой остатками скопившейся пищи при разного рода затруднениях эвакуационной функции пищевода); </li>\r\n<li>аллергический эзофагит); </li>\r\n<li>дисметаболический эзофагит (связан с нарушениями обмена – гиповитаминозами, недостаточностью микроэлементов и тканевой гипоксией, продолжительной интоксикацией организма и т. п.).</li>\r\n</ul>\r\n<p>Рефлюкс-эзофагит развивается вследствие гастроэзофагеального рефлюкса (заброса желудочного содержимого в пищевод). Рефлюкс из желудка в пищевод может возникать по следующим причинам: </p>\r\n<ul>\r\n<li>недостаточность кардии (нижнего пищеводного сфинктера); </li>\r\n<li>грыжа пищеводного отверстия диафрагмы; </li>\r\n<li>недостаточная длина пищевода. </li>\r\n</ul>",
"pathogenesis": "<p>Механизм развития эзофагита обусловлен непосредственным раздражающим химическим, термическим, токсическим или пептическим (при недостаточности кардии и рефлюкс-эзофагите) воздействии на слизистую оболочку пищевода, в редких случаях - бактериальным, токсическим или токсико-аллергическим поражением.</p>\r\n<p> </p>",
"diagnostics": "<p>Диагностика эзофагита включает: </p>\r\n<ul>\r\n<li>Рентгенологическое исследование с контрастным веществом. Наблюдаемый заброс контрастного вещества из желудка в пищевод свидетельствует о выраженном рефлюксе.</li>\r\n<li>Эзофагоскопия - эндоскопическое исследование пищевода.</li>\r\n<li>Эзофагоманометрия — фиксирует различные по характеру нарушения моторики пищевода. </li>\r\n<li>Мониторная рН-метрия пищевода - измерение кислотности в просвете пищевода и желудка; содержимое пищевода будет кислым из-за заброса кислого содержимого из желудка.</li>\r\n</ul>",
"treatment": "<p> Консервативное лечение показано больным с неосложненным течением заболевания. Оно включает в себя: </p>\r\n<p>Общие рекомендации: </p>\r\n<ul>\r\n<li>после принятия пищи избегать наклоны вперед и не ложиться в течение 1,5 часов </li>\r\n<li>спать с приподнятым не менее чем на 15 см головным концом кровати, </li>\r\n<li>не носить тесную одежду и тугие пояса, </li>\r\n<li>ограничить потребление продуктов, агрессивно действующих на слизистую оболочку пищевода (жиры, алкоголь, кофе, шоколад, цитрусовые и т.п.), </li>\r\n<li>отказаться от курения. </li>\r\n</ul>\r\n<p>Медикаментозная терапия: </p>\r\n<ul>\r\n<li>Приём антацидов и производных альгиновой кислоты - препараты снижающие кислотность посредством её нейтрализации. </li>\r\n<li>Антисекреторные препараты - препараты, снижающие кислотность посредством подавления её образования. </li>\r\n<li>Прокинетики - препараты, которые увеличивают тонус нижнего пищеводного сфинктера. </li>\r\n<li>Антибиотикотерапия - применяется для подавления инфекционного процесса. </li>\r\n</ul>\r\n<p>Физиотерапевтическое лечение: </p>\r\n<ul>\r\n<li>при рефлюкс-эзофагите хороший результат дает амплипульстерапия; </li>\r\n<li>снижение болевого синдрома электрофорезом; </li>\r\n<li>грязелечение и бальнеотерапия. </li>\r\n</ul>\r\n<p>При тяжелом течении рефлюкс-эзофагита со стриктурами, язвами и стенозом физиотерапия противопоказана. Операции при стенозе пищевода заключаются в эндоскопическом рассечении стриктур, расширении или бужировании пищевода. По показаниям проводится резекция и пластика пищевода. </p>",
"prevention": "<p>Профилактика эзофагитов подразумевает избегание причин его развития – ожогов горячей пищей, химическими веществами, повреждений инородными телами и т. п. </p>\r\n<p>Профилактика хронического эзофагита – регулярное диспансерное обследование у гастроэнтеролога и при необходимости – лечение. Больным хроническим эзофагитом в качестве профилактики обострений показано санаторно-курортное лечение.</p>",
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},
"code": "B65",
"name": "Шистосомоз [бильгарциоз]",
"icd_name": "Шистосомоз [бильгарциоз]",
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"slug": "b65_shistosomoz_bilgarcioz",
"lead": "Шистосомоз (бильгарциоз) - хронический гельминтоз, вызываемый трематодами рода Schistosoma, с преимущественным поражением мочеполовой системы и кишечника.",
"description": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Шистосомоз - это гельминтное заболевание, вызываемое кровяными сосальщиками-шистосомами; протекающее с токсико-аллергическими реакциями, поражением ЖКТ или мочеполовых органов.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основной причиной патологии являются трематоды, которые относятся к семейству Schistosomatidae.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Человек заражается шистосомозом при таких условиях</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">при единоразовом кратковременном контакте с водой температурой 20-20°С (особенно в сезон после дождей), зараженной яйцами шистосом, включая купание, прохождение брода, поэтому еще имеет название – «зуд пловца»;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">при использовании неочищенной некачественной воды для гигиенических процедур, стирки;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">выполнение сельскохозяйственных работ и рыболовства в эндемичных регионах;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">чрескожное ивазирование и проникновение церкарий происходит даже при абсолютной целостности кожных покровов.</span></li>\r\n</ul>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Наибольшее патогенетическое значение имеют шипы яиц шистосом, которые проникают через кровеносные и лимфатические сосуды, протыкают и повреждают различные ткани и органы, нарушая структуру мочевого пузыря, матки, простаты, печени, селезёнки, лёгких, сердца, желудка и кишечника.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Линия миграции личинок вызывает образование кожных инфильтратов, отечность спровоцирована лизисом эпидермальных клеток.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Токсико-аллергические реакции обычно обусловлены секретами желёз, вырабатываемых в процессе внедрения гельминтов, а также продуктами их жизнедеятельности и распада. В районе скопления паразитарных организмов и их яиц забивается просвет сосудов и проток, возникает варикозное расширение вен, а также возможно развитие кистозных и опухолевых образований. Процесс начинается с отложения яиц в подслизистом слое, что вызывает реакцию на инородное тело и скопление эозинофилов, гигантских клеток, а также гистиоцитов.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">В результате оболочки становятся гиперемированными и отечными, что в дальнейшем может привести к образованию специфической гранулемы – бильгарциомы или шистосомозной язвы, ткани которых претерпевают трансформацию в фиброзную ткань. Кроме того, отмершие яйца в некоторых случаях подвергаются кальцификации.</span></p>",
"diagnostics": "<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">микроскопическое исследование мочи и кала для выявления яиц шистосом</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">общий анализ мочи, который показывает лейкоцитурию, гематурию, протеинурию</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">серологические реакции РСК, ИФА, РНГА для определения антител к гельминтам</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">внутрикожные пробы с антигеном шистосом</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">УЗИ органов брюшной полости и забрюшинного пространства</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">обзорная и экскреторная урография</span></li>\r\n</ul>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"treatment": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Медикаментозная терапия шистосомоза эффективна в ранних стадиях, при отсутствии осложнений; в последних случаях нередко приходится прибегать к хирургическому лечению. При всех формах шистосомоза могут быть использованы антигельминтные средства: празиквантел, тинидазол, метрифонат. Успешность проведенной терапии оценивается на основании повторных гельминтологических исследований и серологических реакций. Хирургическая тактика обычно требуется при осложнениях мочеполового шистосомоза и может включать в себя операции на мочеточниках (при развитии стриктуры), удаление камней из мочевого пузыря и почек.</span></p>\r\n<p> </p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Существует ряд профилактических санитарно-технических рекомендаций для предупреждения распространения и профилактики шистосомоза, к ним относится:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">тщательное мытье рук перед приемами пищи;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">обработка овощей перед их употреблением;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">избегание купания или других водных процедур в водоемах Тропических поясов;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">контроль качества и обеспечение чистой водой эндемичных участков;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">регулярное очищение водоемов;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">уничтожение популяций брюхоногих моллюсков – промежуточных хозяев шистосом;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">санитарно-просветительная работа;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">ранняя диагностика и лечение шистосомоза.</span></li>\r\n</ul>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Первые симптомы возникают практически мгновенно, уже спустя 10-20 минут происходит развитие местной аллергической реакции – крапивницы. В течение первых суток наблюдается мигрирующая сыпь, которая проявляется в виде красных пятен на коже. Больные испытывают сильный зуд, а при повторном заражении – возникает отек. В дальнейшем помимо дерматита острого шистосомного развивается более полная картина заболевания — спустя 1-2 месяца шистосомы у человека могут вызывать:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">кашель и кровохарканье;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">увеличение лимфоузлов;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">гепатомегалию;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">портальную гипертензию;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">асцит;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">повышенную утомляемость;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">астению;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">неспецифические проявления интоксикации в виде лихорадки Катаямы, мышечной и головной боли, озноба, потливости, диареи.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кишечный тип шистосомоза обычно провоцирует боли в животе, диарею и стул с кровью.</span></p>\r\n<p> </p>",
"image": null,
"image_alt": null,
"standard_type": 1,
"danger": 25,
"published": 1,
"parent": null,
"block_rubric": 17,
"standards": []
}
]
}
