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"code": "R33",
"name": "Задержка мочи",
"icd_name": "Задержка мочи",
"gender": 0,
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"cause": [
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"slug": "r33_zaderzhka_mochi",
"lead": "обусловлена различными заболеваниями органов мочеполовой системы, при которых полностью или частично закрывается просвет мочеиспускательного канала в результате поражения центральной нервной системы, воспалительных заболеваний, при травмах ",
"description": "Задержка мочи – состояние, при котором отмечается нарушение адекватного опорожнения мочевого пузыря. Данная ситуация развивается в результате затруднения оттока мочи или при снижении сократительной способности мочевого пузыря.",
"etiology": "<p>Причины, вызывающие задержку мочеиспускания, можно разделить на две группы:</p>\r\n<ol>\r\n<li>Патологические изменения в мочевых органах или их сдавление:</li>\r\n</ol>\r\n<ul>\r\n<li>Травматические повреждения (травма, размозжение, отрыв мочеиспускательного канала).</li>\r\n<li>Закупорка просвета мочеиспускательного канала (камень, полип, дивертикул, рак мочевого пузыря, поствоспалительные стриктуры уретры и т.д.);</li>\r\n<li>Сдавление мочеиспускательного канала патологически измененными органами мочеполовой системы (при аденоме, раке, кисте, абсцессе, склерозе предстательной железы, простатите, фимозе, парафимозе, баланопостите).</li>\r\n<li>Сдавление мочеиспускательного канала патологически измененными органами полости малого таза (рак прямой кишки, парапроктит, опухоли матки, паховые грыжи, аневризма подчревной артерии, гематома промежности и др.).</li>\r\n</ul>\r\n<ol start=\"2\">\r\n<li>Заболевания нервной системы (неврогенная дисфункция мочевого пузыря).</li>\r\n</ol>\r\n<p>К причинам нарушения процессов сокращения и расслабления мышцы мочевого пузыря и пузырно-уретрального сегмента относят опухоли, воспалительные заболевания, травмы спинного и головного мозга, грыжи спинного мозга, нарушение периферической иннервации мочевого пузыря после операций на органах малого таза. В эту же группу причин следует отнести и рефлекторную задержку мочеиспускания после оперативных вмешательств, родов, спинномозговой анестезии.</p>",
"pathogenesis": "<p>При переполнении мочевого пузыря больной не может самопроизвольно опорожнить мочевой пузырь за счет препятствия в области шейки мочевого пузыря или уретры и несостоятельности главной мышцы – детрузора. Поступающая из почек новая порция мочи, повышает внутрипузырное давление и развивается так называемая парадоксальная ишурия, когда моча самопроизвольно начинает вытекать, преодолевая препятствие. При этом мочевой пузырь не опорожняется полностью.</p>",
"diagnostics": "<p>Полная ишурия (как острая, так и хроническая) диагностируется без затруднений. В случае выраженной задержке мочи при физическом осмотре в надлобковом участке выявляют выбухание, которое связано с переполнением пузыря. Может осуществляться перкуссия (простукивание), которая позволяет определить границы переполненного мочевого пузыря.</p>\r\n<p>При менее выраженных случаях ишурии осуществляется УЗИ-диагностика мочевого пузыря и почек. Также неполное задерживание мочи может быть диагностировано в случае наличия большого количества мочи (более трехсот миллилитров), которое определяется посредством катетеризации, осуществленной непосредственно после акта мочеиспускания. Определение остатков может производиться и путем ввода радиоизотопных средств, которые быстро выводятся почками и оседают в мочевом пузыре вместе с оставшейся мочой после мочеиспускания. Кроме этого, применяются следующие диагностические методы:</p>\r\n<ul>\r\n<li>общий анализ крови (с целью определения симптомов воспалительного процесса);</li>\r\n<li>общий анализ мочи (для обнаружения воспаления в мочевых путях и почках);</li>\r\n<li>биохимический анализ крови (осуществляется для выявления разных отклонений в функционировании почек);</li>\r\n<li>ультразвуковая диагностикапростаты.</li>\r\n</ul>",
"treatment": "<p>Неотложное мероприятие – срочное опорожнение мочевого пузыря. На догоспитальном этапе это возможно сделать при помощи катетеризации мочевого пузыря эластичным катетером или надлобковой пункцией. Если ОЗМ продолжается более двух суток, оправдано оставление катетера в мочевых путях с назначением профилактической антибактериальной терапии.</p>\r\n<p>В некоторых случаях прибегают к цистостомии (установка трубочки в мочевой пузырь через переднюю брюшную стенку). После дренирования выявляют и по возможности устраняют причину нарушения оттока мочи.</p>\r\n<p>В случае хронической задержки мочи лечение проводится в зависимости от причины заболевания.</p>\r\n<p>При рефлекторной ишурии осуществляются попытки наладить опорожнение рефлекторно (звук текущей воды из крана, орошение гениталий теплой водой). Если данные методики оказываются неэффективными, применяются медикаментозные средства. Осуществляется подкожное введение прозерина (ингибитора холинэстеразы).</p>",
"prevention": "<p>С целью профилактики задержки мочеиспускания необходимо:</p>\r\n<ul>\r\n<li>осуществлять контроль ПСА (специфический белок, уровень которого в крови увеличивается при болезнях предстательной железы) у мужчин;</li>\r\n<li>избегать переохлаждений, травм мочеполовых органов;</li>\r\n<li>отказаться от злоупотреблений алкоголем;</li>\r\n<li>посещать урологараз в год (касается лиц возрастом после сорока пяти лет);</li>\r\n<li>незамедлительно обращаться к специалисту для коррекции лечения в случае возникновения затруднений мочеиспускания во время приема некоторых лекарственных препаратов.</li>\r\n</ul>\r\n<p> </p>",
"clinical_picture": "<p>Острая задержка мочи характеризуется:</p>\r\n<ul>\r\n<li>мучительными позывами на мочеиспускание;</li>\r\n<li>беспокойством больного;</li>\r\n<li>сильными болями в надлобковой области (могут быть незначительными при медленно развивающейся задержке мочи);</li>\r\n<li>ощущением распирания внизу живота.</li>\r\n</ul>\r\n<p>При ишурии на фоне болезней нервной системы мочеиспускательные позывы или совсем не проявляются, или очень слабо выражены, пациент спокоен, не смотря на выраженное переполнение его мочевого пузыря. Во время диагностирования обнаруживается определенный неврологический синдром (парезы, расстройства чувствительности и пр.)</p>\r\n<p>Хроническая задержка мочи не вызывает выраженного дискомфорта или болезненности в области лона, однако это ощущение носит постоянный и изнуряющий характер. Присутствуют трудности с началом мочеиспускания, оно часто возникает после напряжения мышц брюшного пресса или при помощи надавливания руками на низ живота. После начала мочеиспускания струя мочи слабая и может прерываться. После мочеиспускания часто сохраняется ощущение неполного опорожнения мочевого пузыря, что вызывает необходимость повторной попытки мочеиспускания через малый промежуток времени. Помимо функциональных нарушений развивается ряд психологических проблем и комплексов, связанных с необходимостью часто и подолгу мочиться.</p>\r\n<p>При парадоксальной ишурии моча, независимо от воли больного, постоянно каплями выделяется из мочеиспускательного канала, то есть на фоне полной задержки мочеиспускания наблюдается недержание мочи.</p>",
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"lead": "один из видов кишечной непроходимости, при котором происходит закручивание одного из отделов кишечника вокруг своей оси или вокруг оси брыжейки",
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"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Чтобы произошел поворот, должны возникнуть нетипичные, форс-мажорные обстоятельства. Это могут быть внутренние и внешние причины:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">физические: травма живота, удар об воду, резкий поворот тела, вынужденная непривычная поза, сдавление, сотрясение, подъем тяжестей;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">пищевые:</span><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\"> переедание, особенно после длительного голодания, употребление незнакомой экзотической пищи, большое количество трудноперевариваемой клетчатки в рационе, продолжительный голод;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">органические: спаечные процессы, пупочная грыжа, новообразования, нарушение иннервации кишечника вследствие поражения центральной нервной системы, беременность;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">химические: отравление свинцом или лекарственными препаратами.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При анализе данных о пациентах были выявлены факторы, увеличивающие вероятность возникновения перекручивания кишок:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">возраст старше 55 лет (заворот сигмовидной кишки часто возникает у пациентов старше 60 лет, ободочной и слепой кишки – после 50 лет);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">регулярные запоры или поносы;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">малоподвижный образ жизни;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">тяжелый физический труд;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">фанатичная приверженность различным системам голодания для похудения, нерегулярное питание;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">переедание, особенно перед сном.</span></li>\r\n</ul>",
"pathogenesis": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Перекрут петель кишки вокруг брыжейки вызывает сдавливание сосудов и нервов, из-за чего нарушается питание и иннервация кишечника. Перистальтика сначала усиливается, а затем возникает парез приводящего отдела кишечника - развивается механическая кишечная непроходимость.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Подтвердить или опровергнуть кишечную непроходимость по причине заворота кишечника можно при помощи:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">рентген контрастного исследования с барием;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">ультразвуковой диагностики;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">эндоскопии;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">лапароскопии;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">лабораторной диагностики.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Специализированных лабораторных тестов нет, но общий анализ и биохимия крови могут показать глубину интоксикации и воспалительного процесса. </span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В начале диагностического поиска пациент может находиться в отделении гастроэнтерологии, однако после постановки диагноза он должен быть переведен в отделение абдоминальной хирургии. Консервативную терапию и подготовку к операции начинают с введения назогастрального зонда для разгрузки кишечника, выведения застойного содержимого и газов. Целью инфузионной терапии является восстановление жидкостного баланса, водно-электролитного равновесия крови, уровня белка. Антибактериальная терапия обязательна, если подозревается перитонит или сепсис – её начинают немедленно после госпитализации больного в стационар, если же данные осложнения исключены – за два часа до операции.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заворот тонкого кишечника лечится исключительно оперативным путем. Во время операции хирург должен попытаться расправить перекрут петель, при наличии некроза кишок производится сегментарная резекция тонкой кишки, наложение анастомоза тонкой кишки в тонкую или толстую. Если же во время операции выявляется перитонит – накладывается илеостома, через три месяца производится реконструктивная операция. Операция при завороте слепой кишки преследует своей целью проведение гемиколэктомии с наложением межкишечного анастомоза либо илеостомы (при наличии воспалительного экссудата в брюшной полости). У ослабленных больных может быть проведена чрескожная тифлостомия – она позволит улучшить состояние кишечника, стабилизировать пациента.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Терапию заворота сигмовидной кишки предпочтительно начинать с ректороманоскопии или колоноскопии, во время которых в сигмовидную кишку вводят гибкую трубку для разгрузки кишечника. При необходимости после декомпрессии производится радикальная операция, показаниями к которой являются острый заворот сигмовидной кишки, отсутствие эффекта от консервативной терапии. После операции необходимо продолжить массивную антибактериальную и инфузионную терапию, осуществлять наблюдение за пациентом для раннего выявления осложнений: присоединение инфекции, несостоятельность швов на кишке, образование межкишечных абсцессов и свищей, развитие генерализованной инфекции.</span></p>",
"prevention": "<p><span id=\"docs-internal-guid-5394b655-7fff-aecf-39ae-5fc830ccf9b1\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Для профилактики требуется контроль назначения и приема психотропных и слабительных средств, препаратов, усиливающих или замедляющих перистальтику кишечника. Количество грубых пищевых волокон в рационе должно быть достаточным, но не избыточным. После оперативных вмешательств в обязательном порядке должна проводиться профилактика образования спаек.</span></span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Симптомы по степени их появления и нарастания:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">острая, схваткообразная боль в животе;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">в течение суток боль становится постоянной и труднопереносимой, может дойти до состояния шока;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">асимметрия контуров живота, вздутие;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">тошнота, многократная рвота (может быть с желчью, а в тяжелых случаях с запахом или примесью кала);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">слабость, бледность, низкое артериальное давление, учащенный пульс;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">головная боль, головокружение, возможно спутанное сознание (и другие признаки интоксикации);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">обезвоживание (сухие и потрескавшиеся губы, вязкая слюна, тусклая кожа);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">отсутствие дефекации.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Патология развивается быстро и состояние больного стремительно ухудшается. Летальный исход возможен в течение 2–3 суток, если не будет оказана экстренная медицинская помощь.</span></p>",
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},
"code": "N64.1",
"name": "Жировой некроз молочной железы",
"icd_name": "Жировой некроз молочной железы",
"gender": 0,
"age_min": 12,
"age_max": 100,
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"lead": "доброкачественное заболевание молочной железы, которое возникает при повреждении участка жировой ткани, обычно в результате травм",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Жировой некроз молочной железы – это патологическое состояние, которое характеризуется возникновением очагового процесса омертвения жировой ткани органа. После этого происходит замещение некротического очага новообразованными рубцовыми тканями.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Появление жирового некроза могут спровоцировать различные факторы:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Травмы груди. Составляют более половины всех случаев патологии. Наиболее частый вид травмы — ушибы мягких тканей, которые можно получить в быту, на производстве, при занятиях спортом. Травматизация приводит к нарушениям кровообращения в жировой клетчатке, формированию воспалительного участка и разрастанию соединительнотканных волокон.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Медицинские манипуляции. Являются ятрогенной причиной развития липогранулемы. К таким манипуляциям относят тонкоигольную аспирацию и биопсию тканей молочной железы, в редких случаях— введение силикона или маслянистых веществ. Также стеатонекроз развивается как осложнение хирургических операций (мастэктомии и реконструктивной маммопластики собственными тканями).</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лучевая терапия. Заболеваемость зависит от дозы и объема тканей, подверженных облучению.</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Быстрое снижение массы тела. Наблюдается при соблюдении экстремальных диет, также при некоторых заболеваниях (онкологической патологии, туберкулезе легких, тиреотоксикозе).</span></p>\r\n</li>\r\n</ul>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для правильного диагностирования патологии медицинскому специалисту очень важно на этапе сбора анамнеза получить информацию от пациентки о том, что была получена травма молочной железы.</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Внешний осмотр. Выявляется покраснение или синюшный оттенок кожного покрова на грудной железе. Наблюдаются характерные втянутости и рельефность. Пальпация позволяет определить плотную опухоль, которая во многих случаях отличается болезненностью. Границы уплотнения носят размытый характер.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ультразвуковое исследование. Не способно выявить четкие признаки ЖНМЖ.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Магниторезонансная томография. Позволяет обнаружить неровные границы узловой опухоли и неоднородность ее консистенции.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Обзорная маммография. Выявляет форму и структуру узелковых образований аналогично МРТ. Однако как и в предыдущем исследовании не обнаруживается полной картины. Тем более что симптоматика ЖНМЖ очень похожа на онкологию органа. Поэтому требуются дополнительные исследования. Только на следующем этапе развития болезни, когда соли кальция сформируют обызвествление очага поражения, и он примет сферическую форму новообразования (кальцината), маммография позволит устранить версию о развитии злокачественного процесса.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Биопсия. Проводится для уточнения данных, полученных при проведении УЗИ и рентгенологических исследований. Особенно актуальна на этапе до образования кальцината, напоминающего яичную скорлупу.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Цитологическое и гистологическое исследования. Анализ образцов биопсии для выявления ЖНМЖ при исключении онкологии.</span></li>\r\n</ul>\r\n<p> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Учитывая необратимые очаговые изменения в жировой клетчатке, а также трудности дифференциальной диагностики при жировом некрозе показана органосохраняющая секторальная резекция - удаление части (сектора) молочной железы.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Только постоперационное гистологическое исследование макропрепарата позволяет исключить онкологический процесс. Микроскопически жировой некроз молочной железы представлен узелковыми разрастаниями грануляционной ткани из эпителиоидных клеток, многоядерными гигантскими липофагами и ксантомными клетками вокруг включений жира. Одним из компонентов липогранулем являются жировые кисты - тонкостенные полости, заполненные маслянистой и серозной жидкостью.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основные рекомендации по предотвращению ЖНМЖ:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #242424; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">избегать травм органа;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #242424; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">при получении повреждений грудной железы следует сразу же произвести наложение повязки с тем, чтобы придать ей приподнятое положение;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #242424; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">не затягивать с посещением врача-маммолога;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #242424; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">проходить плановое обследование у профильного медицинского специалиста на систематической основе вне зависимости от получения травм;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #242424; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">проводить самостоятельный осмотр груди не реже 1 раза в месяц для выявления тревожных симптомов.</span></p>\r\n</li>\r\n</ul>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для жирового некроза характерны следующие клинические признаки:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">болезненные ощущения в месте получения повреждения;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">локализованная опухоль округлой формы;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">пальпация выявляет плотную консистенцию опухоли, ее спайку с эпидермисом;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">кожный покров в зоне повреждения имеет красный или синюшный (от серовато-синего до сине-черного цвета) оттенок;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">в области ареолы наблюдается утопление соска в грудную железу (втяжение соска);</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">в отличие от мастита температура тела обычно не повышается;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">деформация органа плотным инфильтратом;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">на поверхности кожного покрова формируются характерные «ямочки»;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">лимфатические узлы увеличиваются;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">омертвение участка, располагающегося среди живой ткани (секвестрация);</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 6.5pt; font-family: Verdana; color: #333333; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">расплавление очага инфекции, сопровождаемое сепсисом.</span></p>\r\n</li>\r\n</ul>",
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