ВОзвращает список болезней. Можно фильтр/искать

search, age, gender, parent, symptoms, sort_name, sort_by, rand, branches
GET /disease/?format=api&ordering=-parent&page=465
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

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                            "name": "Боль в лобной части головы  "
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            "etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основная причина формирования выпячивания &ndash; нарушение структурной целостности стенки сосуда. Патологическое выпячивание может появляться в ответ на влияние повреждающих факторов. К факторам способным провоцировать развитие аневризмы относятся пожилой возраст, нарушение питания, переедание, вредные привычки и нарушение метаболизма, обусловленное сахарным диабетом.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Главными этиологическими факторами, способными вызвать появление аневризмы почечной артерии являются:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инфекционные заболевания, запускающие процессы развития микотической аневризмы. Бактериальное поражение стенок аорты вызывает воспалительные и аллергические реакции, вызывающие разрушение эластических волокон стенке сосуда, что повышает вероятность развития аневризмы.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Атеросклероз вызывает нарушение баланса передачи и утилизации липопротеидов в системном кровотоке, что провоцирует развитие атерогенеза, связанного с повреждением интимы сосудов. В этом случае наблюдается пропитывание жирными кислотами внутреннего слоя артерии, что сопровождается возникновением пролиферации, разрушением клеток и нарушением передачи межклеточного вещества. Приток лейкоцитов в патологический очаг может вызывать появление воспаления, что сопровождается снижением эластической прочности стенки сосуда.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Врожденные заболевания, связанные с внутриутробным нарушением формирования сосудистой стенки также могут вызывать развитие аневризмы. Иногда аневризма может возникать на фоне наследственных заболеваний, связанных с выявлением дефектов в мышечном слое почечных артерий. Дефицит коллагеновых волокон вызывает ослабление мышечного слоя, особенно в местах бифуркации и изгибов.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Травма почечной артерии также в некоторых случаях могут вызывать формирование аневризматического мешка.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>",
            "pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основой механизма развития аневризмы является утрата эластических свойств медиального слоя стенки артерии почки, приводящая к его неспособности сопротивляться давлению крови. Структурные нарушения могут быть врожденными (при синдроме Марфана) или приобретенными (при атеросклерозе, артериите, инфекционных заболеваниях). Вначале происходит разрыв внутреннего слоя сосуда с сохранением целостности остальных слоев. Кровь попадает в образовавшийся дефект, под ее давлением постепенно образуется продольное расслоение классической мешотчатой формы на месте локального поражения. При диффузном циркулярном повреждении артерии выпячивание имеет веретенообразную форму. При ложных аневризмах участок расширения сосуда формируется из соединительной ткани без участия мышечного слоя.</span></p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Непосредственный распад аневризмы ведет к массивному кровотечению. Микроразрывы могут тромбироваться, после чего образуется забрюшинная гематома с последующей капсуляцией. При попадании инфекции в область гематомы происходит нагноение жировой ткани, без медицинской помощи велик риск развития сепсиса. Сдавление почечной чашечно-лоханочной системы выпячиванием большого размера ухудшает пассаж мочи, провоцирует застойные явления, что увеличивает вероятность присоединения пиелонефрита.</span></p>",
            "diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При подозрении на аневризму почечной аорты больному может быть назначено рентгенологическое, ультразвуковое, аортографическое и топографическое исследования, а также ангиосканирование.</span></p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При обследовании пациентов с аневризмой аорты проводят рентгеноскопию и рентгенографию или ультразвуковое исследование мочеполовой системы. Может потребоваться проведение ультразвуковой допплерографии почечной аорты.</span></p>",
            "treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При изолированной, незначительных размеров аневризме почечной аорты может потребоваться проведение выжидательной тактики, основанной на систематическом прохождении рентгенологического исследования для уменьшения вероятности развития различных осложнений.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хирургическое лечение заболевания может потребоваться при выявлении у пациента аневризмы с размером от 0,5 до 1 см аневризматического мешка либо увеличением аневризмы в размерах больше чем на 0,5 см за шесть месяцев.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При разрыве аорты пациент нуждается в проведении экстренного оперативного вмешательства.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Во всех остальных случаях проводят хирургическое удаление аневризмы, основанное на иссечении аневризматического мешка и замещении патологического участка аллотрансплантатом.</span></p>",
            "prevention": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Поскольку самой частой причиной потери эластических свойств сосудистой стенки является атеросклероз, профилактика направлена на предупреждение и корректировку метаболических нарушений. Больным следует придерживаться диеты с низким содержанием соли и жиров, большим количеством овощей и фруктов, принимать антиатеросклеротические препараты.</span></p>",
            "clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При незначительных размерах аневризматического мешка заболевание может никак не проявлять себя. В этом случае его выявляют только при профилактическом осмотре либо обследовании при диагностировании какого-либо другого заболевания. Увеличивающаяся в размерах аневризма оказывает давление на близлежащие структуры, что сопровождается появлением ощущения распирания и тянущих болей в пояснице со стороны поражения.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если выпячивание располагается в почке, то наблюдается компрессия мочеточника, что затрудняет функционирование органа и может вызвать развитие почечной недостаточности или инфаркт почки.</span></p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">У таких пациентов отмечается появление симптомов интоксикации, тошноты, рвоты, слабости, головных болей и головокружений. В случае возникновения мешотчатой формы аневризмы значительно увеличивается риск развития тромбов с дальнейшим разрушением ткани почки. При некрозе почке отмечается появление интенсивных болей в животе, иррадиирующих в низ живота, половые органы либо бедро.</span></p>",
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            "name": "Аневризма сонной артерии",
            "icd_name": "Аневризма сонной артерии",
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            "lead": "расширение участка сосуда с истончением его стенки, от чего возникает риск ее разрыва",
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            "etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основной причиной развития аневризмы бывает врождённая слабость соединительной ткани, заболевания соединительной ткани. Иногда аневризма может развиваться на фоне атеросклеротических изменениях в артерии, при высоком артериальном давлении или после травмы шеи.</span></p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пусковым моментом для развития расширения сонной артерии может послужить лучевая терапия опухолей шеи. Расширение внутренней сонной артерии иногда наблюдается после стентирования или удаления атеросклеротической бляшки.</span></p>",
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            "diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагностической алгоритм аневризмы сонной артерии включает в себя:&nbsp;</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">анамнестические данные;&nbsp;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">результаты физического осмотра (пальпируемая мешковидная опухоль в области шеи); УЗИ шеи. Это исследование служит для определения размера и расширения аневризмы; ангиографию &ndash; золотой стандарт диагностики аневризмы сонной артерии;&nbsp;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">контрастная КТ &ndash; обладает такими преимуществами, как легкая и быстрая применимость; является минимально инвазивным методом, который дает возможность увидеть изменения сосудистой стенки, объемом менее 1 мм;&nbsp;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">магнитно-резонансная ангиография &ndash; является неинвазивным методом, который может визуализировать сосудистые структуры без необходимости использования контрастной среды или рентгеновского излучения. МРА может показывать тромбированные части аневризмы и остаточные характеристики потока крови.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>",
            "treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Неврологи назначают пациентам, у которых диагностирована аневризма сонной артерии,&nbsp; препараты, снижающие концентрацию липидов в крови (ловастатин, симвастин, аторвастин), антиагреганты (клопидогрель, дипиридамол). Больных консультирует сосудистый хирург.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Радикальный метод лечения аневризмы сонной артерии &ndash; хирургическое вмешательство. Сосудистые хирурги проводят следующие операции:</span></p>\r\n<p>&nbsp;</p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Эндартерэктомию сонной артерии и ветвей;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Востановление кровеносного сосуда головного мозга с помощью имплантата;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Эндоваскулярное стентирование сонной артерии;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Клипирование аневризмы;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Эмболизацию аневризмы.</span></li>\r\n</ul>",
            "prevention": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Чтобы предотвратить осложнения аневризмы сонной артерии, следует отказаться от курения, злоупотребления спиртных напитков, нормализовать массу тела. Лица старше пятидесяти лет должны ежегодно проходить скрининговые исследования.</span></p>",
            "clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Аневризма сонной артерии проявляется следующими неврологическими симптомами:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Цефальгией (головной болью);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Диплопией (двоением в глазах);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Птозом (опущение века);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Анизокорией (сужением одного зрачка);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Снижением реакции зрачка на свет;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Выпадением полей зрения;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Периферическим парезом лицевого нерва (опущением нижнего века, нарушением выработки слезы, асимметрией лица).</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В зависимости от локализации аневризмы сонной артерии неврологи определяют следующие симптомы:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Полный или частичный паралич одной половины тела;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Невозможность выполнить произвольные движения;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Речевые расстройства;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Эмоциональную лабильность.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Медленно увеличивающаяся аневризма сонной артерии проявляется симптомами сдавления головного мозга. У пациентов развивается сосудисто-мозговая недостаточность.</span></p>",
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