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"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причины непроходимости пищевода:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Прием агрессивных химических жидкостей (вызывающих химический ожог и, как следствие, стеноз (сужение) пищевода), кислот, щелочей, горячей пищи, напитков.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Язвы (глубокие дефекты в слизистой оболочке) пищевода.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Доброкачественные опухоли пищевода (опухоли, тип клеток которых не отличается от типа клеток органа, из которого они произошли).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Злокачественные опухоли пищевода (опухоли, тип клеток которых отличается от типа клеток органа, из которого они произошли).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кардиоспазм (заболевание, проявляющееся сужением пищевода в месте его впадения в желудок).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дивертикулы пищевода (мешковидные выпячивания стенки пищевода в просвет пищевода).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Попадание в пищевод инородных тел (например, игрушек, пуговиц, гвоздей, рыбных костей, зубных протезов).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гастроэзофагеальная рефлюксная болезнь (заболевание, характеризующееся забросом содержимого желудка в пищевод) с язвенным эзофагитом (воспалением слизистой оболочки пищевода и развитием на ней глубоких дефектов).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Механические травмы (проглатывание инородных тел (например, гвоздей, ножей, вилок), ранения шеи, грудной клетки и др.).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Последствия инфекций (туберкулеза (заболевания, вызываемого палочкой Коха), микозов (грибковых заболеваний) и др.).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Системные заболевания соединительной ткани (болезни, связанные с повреждением соединительной ткани в кровеносных сосудах, различных органах и тканях). Проявляются разрастанием фиброзной (волокнистой) ткани, вследствие чего уменьшается просвет пищевода.</span></li>\r\n</ul>\r\n<p> </p>",
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"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Консультация гастроэнтеролога требуется для проведения первичной диагностики непроходимости пищевода. После установления окончательного диагноза пациент направляется в отделение хирургии. Выявление рубцовых изменений, стриктур и стенозов производится с помощью рентгенографии пищевода с контрастированием. Консультация врача-эндоскописта нужна для назначения и проведения эзофагоскопии, выявления и верификации непосредственных причин непроходимости пищевода (опухолей, специфических заболеваний, инородных тел и др.). Также для диагностирования опухоли пищевода большое значение имеют компьютерная томография ОГК с контрастированием, эндосонография пищевода.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При подозрении на рак пищевода может потребоваться эндоскопическая биопсия, хромоскопия пищевода и желудка. При системных заболеваниях, подозрении на ахалазию кардии показана эзофагеальная манометрия. При наличии у больного специфических заболеваний (сифилис, туберкулез, склеродермия) план обследования соответствует выявленной патологии.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лабораторные анализы при непроходимости пищевода отражают патологические изменения, вызванные основным заболеванием. В биохимическом анализе крови может отмечаться анемия, снижение уровня общего белка и нарушение соотношения белковых фракций, гиповитаминоз, признаки гиперкатаболизма.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение пациентов с доброкачественной непроходимостью пищевода осуществляется в отделении хирургии, при наличии рака пищевода пациент может находиться в отделении гастроэнтерологии или онкологии. Схема лечения непроходимости пищевода зависит от причины данной патологии.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При доброкачественной непроходимости пищевода предпочтительно использовать эндоскопическое расширение стеноза пищевода, эндоскопическое бужирование стенозированного участка. В последние годы широко применяются такие методики, как эндоскопическое рассечение рубцовой стриктуры пищевода, а при тяжелых формах непроходимости - эндопротезирование (стентирование) пищевода. Для восстановления проходимости пищевода может потребоваться извлечение инородного тела, оперативное удаление опухоли, кисты пищевода. Также проводится консервативное либо оперативное лечение заболевания, которое привело к сдавлению пищевода извне.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Злокачественные формы непроходимости пищевода требуют проведения патогенетического лечения: лучевой либо химиотерапии, хирургического удаления опухоли с последующей эзофагопластикой. Консервативные мероприятия включают в себя нормализацию уровня основных нутриентов в крови, электролитов. При необходимости корректируется питание, назначаются препараты для лечения анемии.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Специфической профилактики непроходимости пищевода не существует. Для предотвращения данного состояния следует избегать этиологических и патогенетических факторов непроходимости пищевода.</span></p>",
"clinical_picture": "<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дисфагия (нарушение глотания). В зависимости от выраженности сужения пищевода возможны разные степени дисфагии: от незначительного дискомфорта во время еды (поперхивание) до невозможности потребления сухой, жесткой, плохо пережеванной пищи, а в тяжелых случаях — и жидкой пищи.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Одинофагия — возникновение болей (или просто неприятных ощущений) за грудиной при глотании. Иногда боль может отдавать в левую часть грудной клетки, под лопатку, в нижнюю челюсть, что может имитировать сердечный приступ (нарушение кровоснабжения сердца, проявляющееся болями за грудиной).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рвота съеденной накануне пищей, которая бывает с примесью крови.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отрыжка с запахом тухлых яиц.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Снижение массы тела из-за уменьшения потребления пищи, при этом аппетит остается хорошим.</span></li>\r\n</ul>\r\n<p> </p>",
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"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дискинезии пищевода - это нарушения его моторной (двигательной) функции, заключающиеся в изменении продвижения пищи из полости глотки в желудок при отсутствии органических поражений пищевода.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дискинезия пищевода может развиться первично (при отсутствии другой патологических процессов) либо вторично - на фоне заболеваний пищевода (эзофагиты, грыжа пищеводного отверстия диафрагмы, дивертикулы и рак пищевода) и других органов (системные заболевания соединительной ткани, сахарный диабет, тяжелая патология нервной системы, язвенная болезнь желудка, хронический холецистит), приема некоторых лекарственных препаратов.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нарушение моторики и формирование первичной дискинезии пищевода происходит в результате воздействия стрессов, сбоев в развитии мышечной оболочки и нервного аппарата пищевода. В результате этих причин возникает дискоординация нервной и гуморальной регуляции сокращения стенки пищевода, развивается двигательная дисфункция.</span></p>",
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"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Консультация врача-гастроэнтеролога и эндоскописта требуется всем пациентам с подозрением на дискинезию пищевода. Наиболее информативным методом диагностики является рентгеноскопия пищевода. На гипермоторную дискинезию во время исследования указывают зубчатые контуры пищеводной стенки, задержка прохождения контраста более 5 сек., локальные деформации, неперистальтические сокращения пищевода при глотании; на другие виды дискинезии - спазм сфинктеров, отсутствие газового пузыря желудка (при ахалазии кардии).</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эзофагеальная манометрия выявляет спастические сократительные волны в пищеводе с повышением давления более 30 мм. рт. ст., неполную релаксацию нижнего сфинктера, эпизоды нормальной перистальтики (дифференцируют спазм пищевода и ахалазию кардии). Эзофагоскопия, анализ кала на скрытую кровь используются для выявления осложнений дискинезии пищевода и сопутствующих заболеваний. Эндоскопическое исследование может провоцировать усиление болей за грудиной, не несет большой информационной нагрузки.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для лечения широко используется диета – частое дробное питание небольшими порциями. Пища должна быть термически, механически и химически щадящей, исключаются продукты с высоким содержанием клетчатки. Следует избегать физических нагрузок, нагибания, переедания.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Из медикаментов, нормализующих моторику пищевода и обладающих спазмолитическим действием, назначают блокаторы кальциевых каналов, антихолинолитики, нитраты. Широкое применение нашли и седативные средства. Проводится лечение осложнений дискинезии (ГЭРБ, эзофагитов). Хирургическое вмешательство показано только при неэффективности консервативного и тяжелых формах заболевания.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика заключается в регулярном прохождении медосмотров, своевременной терапии заболеваний, которые могут привести к дискинезии пищевода.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Наиболее распространёнными симптомами, сопровождающими спазм пищевода, являются:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">острая загрудинная боль, напоминающая приступ стенокардии;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">дисфагия (затруднённое глотание);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">одинофагия (болезненное глотание);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">жжение за грудиной;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">регургитация (возврат содержимого желудка в полость рта);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">болезненная обструкция с ощущением застревания.</span></li>\r\n</ul>",
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"lead": "сочетанное воспаление слизистой оболочки желудка (чаще его привратникового отдела) и 12-перстной кишки, характеризующееся нарушением секреции и моторики желудочно-кишечного тракта",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гастродуоденит – это воспалительное заболевание слизистой оболочки пилорической (привратниковой) зоны желудка и его непосредственного продолжения – двенадцатиперстной кишки, с которой желудок сообщается через сфинктер-привратник. Из-за воспалительного процесса нарушаются процессы пищеварения (нормальная моторика кишечника и выработка желудочного сока), что сказывается на переваривании пищи в целом. </span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Выделяют эндогенные и экзогенные причины развития гастродуоденита. При повышенном кислотообразовании и малой продукции слизи, нарушении гормональной регуляции секреции развивается эндогенный гастродуоденит. Также вызвать развитие гастродуоденита могут заболевания печени и желчных путей, сбои в работе эндокринной системы.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К экзогенным факторам развития относят физические – например, употребление острой, холодной или горячей пищи, воздействие химических препаратов (пестицидов). Немаловажное значение имеет и проникновение в пищеварительный тракт бактерии Helicobacter pylori.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К основным причинам гастродуоденита можно отнести:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Скудное или же очень жирное и острое питание;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Несоблюдение режима приема пищи, еда всухомятку;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Различные стрессы, психологическое давление;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заражение Helicobacter pylori;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инфекции, которые развивались в полости рта и глотке;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В последнее время подмечено, что причинами поверхностного гастродуоденита может быть генетическая предрасположенность к таким заболеваниям.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кроме того, различают острую и хроническую формы гастродуоденита, когда периоды ремиссии чередуются с обострениями.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причины развития острой формы гастродуоденита:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Токсическое воздействие химических веществ и испорченной пищи, раздражающее слизистую желудка и кишечника;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Употребление острых специй и приправ;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Высокая концентрация остаточных пестицидов в продуктах питания;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Осложнения кишечных инфекций и хронических соматических заболеваний;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Повышенное продуцирование в желудке соляной кислоты в сочетании со снижением защитных свойств слизистой оболочки, протекающее на фоне стресса и нарушения режима питания.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагностировать гастродуоденит может врач-гастроэнтеролог, проведя осмотр или необходимые исследования: эзофагогастродуоденоскопию, в случае необходимости – с биопсией слизистой оболочки желудка.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Также необходимо провести исследование желудочной секреции – рН-метрию желудка и двенадцатиперстной кишки. По результатам этих анализов можно определить, какую форму имеет гастродуоденит – с повышенной или пониженной кислотностью, и, соответственно, назначить верное лечение.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Методы диагностирования гастродуоденита:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Фиброэзофагогастродуоденоскопия (ФЭГДС) – точный и информативный метод эндоскопического исследования желудка и 12-перстной кишки при помощи эндоскопа, позволяет оценить тяжесть и характер повреждений, форму гастродуоденита.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Морфологическое исследование тканей слизистой, взятых во время проведения ФЭГДС – осуществляется при помощи микроскопа на клеточном уровне, позволяет диагностировать форму и особенности заболевания.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Рентгеновское исследование с контрастным веществом желудка и 12-перстной кишки – метод менее информативен, чем ФЭГДС, применяется редко.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Интрагастральная pH-метрия – измерение кислотности желудочного сока при помощи электродов, введенных в желудок, помогает определить схему лечения.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Бичастотная интрагастральная импедансометрия – измерение активности желез, продуцирующих соляную кислоту, точно определяет кислотность желудочного сока.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">УЗИ желудка и кишечника – малоинформативный метод, позволяющий определить косвенные признаки гастродуоденита.</span></li>\r\n</ul>\r\n<p> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение тяжелого гастродуоденита должно осуществляться в отделении гастроэнтерологии. При развитии острого состояния для полного излечения достаточно одного курса терапии и соблюдения строгой диеты. Жалобы на неоднократные эпизоды заболевания требуют повторной консультации гастроэнтеролога и проведения полноценного лечения.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пациенту с гастродуоденитом обязательно назначается лечебная диета. В периоды обострения требуется соблюдение особых правил: пища должна быть механически, химически и термически щадящей. Нельзя употреблять острые, копченые и экстрактивные вещества. В период ремиссии специальная диета не требуется, достаточно здорового рационального питания. Для предупреждения рецидивов рекомендуется навсегда отказаться от курения, алкоголя, газированных напитков, крепкого кофе.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лекарственная терапия гастродуоденита зависит от клинической формы заболевания. При повышенной кислотности желудка назначаются антацидные препараты, ингибиторы протонной помпы; при пониженной – ферментные препараты и натуральный желудочный сок. Обнаружение хеликобактерной инфекции требует обязательного назначения антибактериальных препаратов, которые в сочетании с препаратами висмута и ингибиторами протонной помпы позволяют добиться практически полной эрадикации возбудителя. Также комплексная терапия должна включать в себя спазмолитики, репаративные препараты, фитотерапию. В периоде ремиссии рекомендуется санаторно-курортное лечение, употребление минеральных вод.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Главной проблемой в ведении гастродуоденитов является то, что многие пациенты пытаются лечиться самостоятельно, нерационально используя симптоматические средства, бросая начатую терапию при ослаблении симптомов заболевания, не добившись полного излечения. Правильное и своевременное лечение хронического гастродуоденита является лучшей профилактикой язвенной болезни. Даже после достижения стойкой ремиссии требуется постоянное соблюдение принципов рационального питания, здорового образа жизни для предупреждения рецидивов.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика гастродуоденита во многом перекликается с основными принципами лечения. Для предупреждения заболевания необходимо вести здоровый образ жизни, отказаться от таких вредных привычек, как курение и прием спиртного, употребления большого количества крепкого кофе. Необходимо правильно питаться – включать в рацион больше свежих овощей и фруктов, каш, нежирного мяса и рыбы. Следует отказаться от газированных напитков, острой и пряной пищи, жареных блюд. </span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К неспецифическим симптомам, связанным с общим ухудшением самочувствия, относятся слабость, вялость, головная боль, раздражительность, расстройство сна. На этом фоне могут манифестировать кардиалгия, аритмия, гипотония.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Поступающие в организм питательные вещества плохо усваиваются, поэтому больной «беспричинно» худеет. Признаки нарушенного всасывания витаминов и микроэлементов проявляются следующим образом: </span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нарушено усвоение жиров: стеаторея (обильный кашицеобразный зловонный стул светлого цвета);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нарушено усвоение белков: сухие волосы, выпадение волос, отеки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">нарушено усвоение углеводов: метеоризм (с которым связан дискомфорт в животе), обильная диарея;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">дефицит витаминов и полезных микроэлементов: ухудшается состояние кожи и ногтей, снижается иммунитет.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Симптомы гастродуоденита могут появиться внезапно, через некоторое время после приема пищи. В некоторых случаях приступ может обостриться натощак.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Боль при гастродуодените носит ноющий или схваткообразный характер, ощущается в верхней средней части живота, может иррадиировать в область пупка или подреберья. В отличие от язвенной болезни, боль носит эпизодический характер, отсутствует сезонность ее возникновения, она менее интенсивная.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Чувство распирания и давления в области живота может быть связано с ферментной недостаточностью. Пациенты жалуются на неприятный горьковатый или кислый привкус во рту, не связанный с приемом пищи, сниженный аппетит.</span></p>",
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{
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}
]
}