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"code": "H21.0",
"name": "Гифема",
"icd_name": "Гифема",
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"lead": "патологическое состояние глаза, при котором в его передней камере (она находится между роговицей, радужкой и хрусталиком) появляется кровь",
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"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Возникновение гифемы может быть вызвано одной из этих причин:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Травма глаза. Это особенно частая причина возникновения внутриглазных кровотечений. При этом травмы глаза подразделяются на два вида – проникающие, с поражением глазных оболочек и непроникающие (тупые), без поражения оболочек глаза.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причиной излития крови в переднюю камеру при проникающей травме является разрыв глазных оболочек, сопровождающийся разрывом сосудов. В случае непроникающей травмы, разрыв сосудов и кровотечение возникают из-за резкого скачка внутриглазного давления. Кроме разрыва сосудов при непроникающей травме, причиной излития крови может стать разрыв внутренних оболочек глаза (радужной оболочки, выполняющей функцию защитной мембраны в передней части сосудистой оболочки глаза; цилиарного тела в сосудистой оболочке глаза, состоящего из группы мышц, изменяющих форму хрусталика; хориоидеи – сосудистой оболочки, обеспечивающей питание сетчатки).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Офтальмологические операции. Осложнением как полостных, так и лазерных операций на глазах нередко становится возникновение гифемы. Это происходит из-за повреждения в процессе хирургического вмешательства сосудов радужки и цилиарного тела, результатом чего и становится кровотечение. С такими кровотечениями врачи легко справляются во время хирургической операции. Однако, и в послеоперационном периоде, практически несколько месяцев риск возникновения гифемы сохраняется, так как кровотечение может возникнуть вновь из поврежденного на операции сосуда. Кроме того, в месте операционного разреза, нередко происходит рост новообразованных сосудов, с дефектами сосудистой стенки и предрасположенных к разрывам.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Некоторые заболевания глаз. Болезни глаз, сопровождающиеся ростом по радужной оболочке новообразованных сосудов, также могут являться причиной возникновения гифемы. К этим заболеваниям относят некомпенсированный тяжелый сахарный диабет, тромбоз центральной вены сетчатки и ее ветвей, внутриглазные опухолевые образования и пр. Растущие новообразованные сосуды крови имеют неполноценные хрупкие стенки, которые при малейшем колебании артериального или внутриглазного давления рвутся с излитием крови в переднюю камеру глаза.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Общие заболевания организма. Системные заболевания, связанные с нарушением свертываемости крови, такие как гемофилия, анемия или рак крови, нередко приводят к возникновению гифемы, казалось бы, без видимых офтальмологических причин. Кроме того, возникновению гифемы может способствовать злоупотребление алкоголем.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кровь, излившаяся в переднюю камеру, может вызывать некоторые осложнения. Как правило, они возникают при выраженной гифеме, с полностью заполненной кровью передней камерой. Особенно серьезными осложнениями в подобной ситуации становятся: прокрашивание кровью роговицы и стойкое повышение внутриглазного давления – вторичная глаукома. Прокрашивание роговицы кровью приводит к ухудшению зрения даже после того, как сама гифема рассосется, так как оно долго не проходит и со временем способно даже увеличиваться.</span></p>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Диагностика гифемы основывается на данных анамнеза, объективного осмотра, результатов проведенной биомикроскопии глаза, гониоскопии, визометрии, тонометрии, ультразвукового В-сканирования. В анамнезе у большинства пациентов наблюдается травматическое повреждение глазного яблока, оперативные вмешательства, заболевания крови или патологии глаз, сопровождающиеся усилением процессов ангиогенеза. При объективном осмотре микрогифема не определяется. Для ее верификации необходимо провести микроскопию внутриглазной жидкости, в которой будут определяться следы форменных элементов крови. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Методом биомикроскопии с использованием щелевой лампы определяется пул циркулирующих эритроцитов в жидкости передней камеры глаза или цельная кровь. Выявляются другие органические изменения в результате травмы (субконъюнктивальные кровоизлияния, факодонез, разрыв сфинктера радужки, инородные тела глаза и т. д.). Ультразвуковое В-сканирование позволяет визуализировать признаки травматического повреждения даже при тотальной гифеме и определить источник кровотечения.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Микрогифема не требует специального лечения. Консервативная терапия на I, II стадии заболевания предполагает местное применение капель кортикостероидов (преднизолон) и мидриатиков (атропин). Угнетая процессы фибринолиза, кортикостероиды профилактируют развитие рецидивов. Антифибринолитической активностью обладает аминокапроновая кислота, которая используется системно. Атропин предотвращает образование передних синехий, снижает проявления фотофобии, уменьшает выраженность спазма аккомодации. При повышении ВГД рекомендован пероральный прием ингибиторов карбоангидразы (ацетазоламид, дорзоламид).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хирургическое лечение гифемы проводится на III, IV стадии заболевания. Для промывания передней камеры глаза выполняются два параллельных друг другу парацентеза. В одно из отверстий вливают сбалансированный кристаллоидный раствор, через второе удаляется кровь и образовавшиеся кровяные сгустки. Проведение трабекулэктомии улучшает отток крови, приводит к снижению ВГД и ликвидирует зрачковый блок. Облитерация послеоперационной фистулы происходит самостоятельно.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение пациентов с серповидно-клеточной анемией в анамнезе исключает использование ингибиторов карбоангидразы. Препараты данной группы снижают парциальное давление кислорода в жидкости передней камеры, что ведет к деформации эритроцитов. Деформированные форменные элементы приводят к блокаде путей оттока внутриглазной жидкости, что провоцирует повышение ВГД.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лечение гифемы в большинстве случаев проводится амбулаторно. Стационарному лечению подлежит группа больных с высокими значениями ВГД, не поддающимися медикаментозной коррекции, пациенты с патологиями крови и в возрасте до 3 лет. Рекомендован постельный режим с максимально возможным ограничением двигательной активности. В постели следует лежать с приподнятым на 40-50 градусов изголовьем. На протяжении дня необходимо носить защитный щиток на пораженном глазу.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В целях предупреждения данной патологии следует соблюдать технику безопасности при выполнении потенциально опасных действий, которые могут стать причиной травм глаз. Также при появлении любых патологий зрения необходимо проводить своевременное и адекватное лечение или коррекцию.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Клиническая картина гифемы зависит от объема крови в передней камере глаза. При микрогифеме заболевание носит латентное течение. Иногда пациенты отмечают незначительный дискомфорт, гиперемия не характерна. Для первой стадии свойственно появление «тумана» перед глазами. Больные могут наблюдать узкую полоску красно-коричневого цвета при самостоятельном осмотре. При травматическом происхождении возможно развитие фотофобии и болевого синдрома. На второй и третьей стадии нарастают клинические проявления: уровень крови заметен на расстоянии, появляется пелена перед глазами, зрение снижается незначительно. Присоединяется неврологическая симптоматика: «мушки» перед глазами, головная боль, головокружение. Тотальная, или «черная», гифема сопровождается полной потерей зрения. У ряда пациентов сохраняется только световосприятие. Даже после проведенного лечения в роговице определяется следовое количество форменных элементов, что изменяет ее окраску и отрицательно влияет на зрительные функции.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Скопление крови в передней камере глаза провоцирует повышение внутриглазного давления, что является предиктором развития вторичной глаукомы. К отдаленным осложнениям гифемы относится образование передних синехий по периферии глазного яблока. Сочетание повышения ВГД, окклюзии сосудов и контузии при травматическом кровоизлиянии приводит к атрофии зрительного нерва. Данная патология вызывает расщепление цилиарной мышцы и смещение радужки и хрусталика кзади, как следствие сужается шлеммов канал вплоть до его полной блокады. Эти обстоятельства, а также механическое давление скопившегося объема крови приводит к углублению угла, ограниченного спереди роговицей и склерой, сзади – цилиарным телом и радужкой, что лежит в основе рецессии угла передней камеры глаза.</span></p>",
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}
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}