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},
"code": "G90",
"name": "Расстройства вегетативной [автономной] нервной системы",
"icd_name": "Расстройства вегетативной [автономной] нервной системы",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
3
],
"periodicity": 1,
"slug": "g90_rasstroystva_vegetativnoy_avtonomnoy_nervnoy_sistemy",
"lead": "Нарушение здоровья, относящееся к группе другие нарушения нервной системы",
"description": "Синдром, характеризующийся нарушениями вегетативной регуляции внутренних органов - сердечно-сосудистой системы, желудочно-кишечного тракта, органов дыхания, желез внутренней секреции.",
"etiology": "<p>Нарушение деятельности внутренних систем человека происходит из-за сбоев в процессе нервной регуляции. Причинами могут быть:</p>\r\n<p> </p>\r\n<ul>\r\n<li>Нарушения в эндокринной систем (ожирение, сахарный диабет);</li>\r\n<li>гормональные сбои или возрастные гормональные изменения в организме (беременность, менструальный цикл, климакс, пубертатный период);</li>\r\n<li>Наследственная предрасположенность;</li>\r\n<li>травмы, ранения, хирургические операции</li>\r\n<li>хронический стресс, мнительность;</li>\r\n<li>Курение, употребления алкоголя и наркотических препаратов;</li>\r\n<li>Несоблюдение правил правильного питания;</li>\r\n<li>Хронические инфекции по типу кариозных образований и тонзиллита;</li>\r\n<li>Аллергическая реакция;</li>\r\n<li>Интоксикация;</li>\r\n<li>Влияние производственных факторов (вибрация, облучение)</li>\r\n<li>Инфекционное поражение периферической вегетативной нервной системы (СПИД, герпес, сифилис, лепра)</li>\r\n</ul>\r\n<p>У детей 1 года жизни заболевания вегетативной нервной системы возникают из-за гипоксии плода (нехватки кислорода при внутриутробном развитии), а также из-за перенесенных стрессов. У детей психика не настолько устойчива, как у взрослых, поэтому для них любая проблема может вызвать психическую травму.</p>",
"pathogenesis": "<p>Основную роль в патогенезе вегетативной дистонии играет нарушение вегетативной регуляции и развитие вегетативного дисбаланса. Отношения между симпатической и парасимпатической вегетативными нервными системами соответствуют принципу «качающегося равновесия»: повышение тонуса одной системы влечет за собой возрастание тонуса другой. Такая форма вегетативного обеспечения позволяет поддерживать постоянство внутренней среды и создавать условия для повышенной лабильности физиологических функций. Клинико-экспериментальные исследования обнаружили эту лабильность практически во всех системах – вариации ритма сердца, артериального давления, температуры тела и других показателей. Выход этих колебаний за пределы нормального диапазона повышает уязвимость системы вегетативной регуляции для повреждающих факторов. В таких условиях экзогенные либо эндогенные стимулы могут приводить к предельному напряжению регуляторных систем, а затем к их «поломке» с клинической манифестацией в виде расстройства вегетативной нервной системы.</p>",
"diagnostics": "<p class=\"txt\">Диагностика вегетативной дистонии преимущественно клиническая. Лабораторные и инструментальные методы требуются для исключения соматических заболеваний, имеющих сходную клиническую картину.</p>\r\n<p class=\"txt\">Дифференциальную диагностику проводят с заболеваниями эндокринных органов (гипо- и гипертиреоз, сахарный диабет, феохромоцитома), сердечно-сосудистой системы (пароксизмы нарушений сердечного ритма и проводимости, сопровождающиеся обмороками), неврологическими заболеваниями (эпилепсия).</p>\r\n<p>Основные (обязательные) диагностические обследования, проводимые на амбулаторном уровне:</p>\r\n<ul>\r\n<li>измерение АД, ЧСС, ЧД в покое, при физической, умственной и эмоциональной нагрузках;</li>\r\n<li>ортостатическая проба – используется для анализа работы сердечно-сосудистой системы при вставании и помогает определить как функционирует симпатический отдел вегетативной нервной системы;</li>\r\n<li>общий анализ крови;</li>\r\n<li>определение натрия, кальция, калия в сыворотке крови;</li>\r\n<li>определение глюкозы в сыворотке крови;</li>\r\n<li>общий анализ мочи;</li>\r\n<li>электрокардиографическое исследование (в 12 отведениях);</li>\r\n</ul>\r\n<p>Основные (обязательные) диагностические обследования, проводимые на стационарном уровне:</p>\r\n<ul>\r\n<li>холтеровское (суточное) мониторирование электрокардиограммы;</li>\r\n<li>суточное мониторирование АД;</li>\r\n<li>тест на толерантность к глюкозе;</li>\r\n<li>ЭЭГ-видеомониторинг.</li>\r\n</ul>\r\n<p>Дополнительные диагностические обследования, проводимые на стационарном уровне:</p>\r\n<ul>\r\n<li>Коагулология;</li>\r\n<li>определение гормонов щитовидной железы ИФА-методом;</li>\r\n<li>МРТ головного мозга;</li>\r\n<li>УЗДГ сосудов головы;</li>\r\n<li>Ультразвуковая диагностика комплексная;</li>\r\n<li>Рентгенография обзорная органов грудной клетки;</li>\r\n<li>Люмбальная пункция;</li>\r\n<li>Исследование спиномозговой жидкости.</li>\r\n</ul>\r\n<p> </p>\r\n<p> </p>\r\n<p> </p>\r\n<p> </p>\r\n<p> </p>",
"treatment": "<p><strong>Немедикаментозное лечение </strong></p>\r\n<p>Включает соблюдение режима труда и отдыха, освобождение от дополнительных нагрузок.</p>\r\n<p>При вторичных нарушениях вегетативной нервной системы необходима диетотерапия, согласно протокола основного заболевания (сахарный диабет, онкологические заболевания, заболевания ЖКТ и т.д.)</p>\r\n<p>Для детей старше пяти лет можно применять иглорефлексотерапию</p>\r\n<p>Показана ранняя реабилитация (массаж, водные процедуры, игротерапия, музыкотерапия, индивидуальная или групповая психотерапия, ЛФК).</p>\r\n<p><strong> Медикаментозное лечение </strong></p>\r\n<p>Назначается только в случае неэффективности немедикаментозных мероприятий или в сочетании с ними.</p>\r\n<p>В случае преобладания активности симпатического отдела нервной системы назначают седативные средства. По показаниям - бензодиазепиновые производные альфа- и бета-адреноблокаторы.</p>\r\n<p>При преобладании тонуса парасимпатической системы используют средства, повышающие АД, холинолитики центрального и периферического воздействие.</p>\r\n<p>В связи с частым сочетанием вегетативных и эмоциональных нарушений применяют антидепрессанты, противотревожные (анксиолитики) и снотворные препараты. Лечение следует проводить с участием психотерапевта или психиатра.</p>",
"prevention": "<p>Профилактику следует начинать с немедикаментозных мероприятий – нормализации режима дня, питания, прогулки на свежем воздухе, водные процедуры. Профилактика нарушений вегетативной нервной системы возможна лишь при ранней их диагностике, определяемых задолго до появления жалоб. В основе профилактики лежит здоровый образ жизни. Оптимизация физической активности и сбалансированное рациональное питание с низкой калорийностью и антисклеротической направленностью – главные составляющие профилактики заболеваний нервной и сердечно-сосудистой систем.</p>",
"clinical_picture": "<p>В клинике расстройств вегетативной нервной системы выделяют гипотензивный и гипертензивный варианты, ведущим проявлением которых являются изменения артериального давления (АД), а также кардиологический вариант с преобладанием болей в области сердца.</p>\r\n<p>Гипотензивный тип устанавливают в случаях, когда величина систолического АД колеблется в пределах 110-80 мм рт. ст., а диастолического 45-60 мм рт. ст. и имеются клинические признаки хронической сосудистой недостаточности.</p>\r\n<p>Жалобы больных, наиболее значимых для диагноза, - зябкость кистей, стоп и склонность к ортостатическим расстройствам (головокружение при перемене положения тела, резком повороте головы, туловища), непереносимость транспорта. Наблюдаются проявления астеновегетативного синдрома: быстрая истощаемость умственной и физической активности, снижение памяти, концентрации внимания, слабость, повышенная утомляемость. Свойственны лабильность настроения, высокая тревожность, склонность к ипохондрии.</p>\r\n<p>При осмотре определяют астеническое телосложение, бледность кожных покровов, мраморность, пастозность тканей, снижение температуры кожи конечностей, влажность ладоней и стоп, учащенное сердцебиение. Нередко выявляется снижение аппетита, тошнота, не связанная с приемом пищи, периодические боли в животе, запоры, головные боли.</p>\r\n<p>Гипертензивный тип характеризуется транзиторным повышением АД и связанные с ним головные боли, боли в области сердца, головокружения, сердцебиения, мелькание мушек перед глазами, чувство жара, приливов к голове и шее. Головная боль возникает преимущественно при психоэмоциональных и физических перегрузках, носит ноющий, иногда пульсирующий характер с преимущественной локализацией в затылке. Отмечается эмоциональная лабильность, повышенная утомляемость, раздражительность, нарушения сна, ипохондрию, метеозависимость.</p>\r\n<p>Кардиалгический тип устанавливают, если нет изменений АД, но есть жалобы на сердцебиение или перебои в сердце, боли в области сердца, одышку. Объективно выявляется тахикардия, выраженная синусовая аритмия или экстрасистолия.</p>\r\n<p>В крайней степени выраженности заболевание может проявляться вегетативными кризами, нейрорефлекторными синкопальными состояниями, перманентными вегетативными нарушениями. Вегетативные кризы могут быть симпатическими, парасимпатическими и смешанными. </p>\r\n<p>При преобладании тонуса симпатической нервной системы (симпатикотония) возникают типичные вегетативные кризы (панические атаки). При осмотре выявляются тахикардия, побледнение кожных покровов, повышение АД, ослабление перистальтики кишечника, расширение зрачков, озноб, ощущение нехватки воздуха, одышка. Важно присутствие тревоги, беспокойства, ощущение страха, который может носить витальную окраску (больной опасается за свою жизнь, хотя видимой угрозы не существует). Возможен страх сойти с ума, совершить неконтролируемое действие, нанести увечья себе или близким.</p>\r\n<p>Гипервентиляционный криз также включает в себя сочетание вегетативных и аффективных нарушений. У больного наблюдаются усиленное, учащенное дыхание, ощущение нехватки воздуха с преимущественным затруднением вдоха. Возможно появление чувства кома в горле, «мурашек» на коже, похолодания рук и ног, неустойчивости походки. Появляется страх потерять сознание, умереть. Вследствие преходящей гипокалиемии возможно развитие гипервентиляционной тетании с напряжением мышц предплечий и кисти («рука акушера»), голеней и стоп (карпопедальные спазмы). Кисти и стопы становятся влажными, холодными на ощупь. Приступ может закончиться обмороком.</p>\r\n<p>Ваготонические кризы сопровождаются брадикардией, затруднением дыхания, покраснением кожи лица, потливостью, саливацией, понижением АД, желудочно-кишечными дискинезиями. Возможно снижение уровня глюкозы в крови. Приступ также может заканчиваться кратковременной утратой сознания. У отдельных больных возможны аллергические явления в виде крапивницы или отека Квинке. Такие кризы могут провоцироваться пребыванием в душном помещении, несвоевременным приемом пищи («голодный обморок»), интенсивными нагрузками, волнением.</p>\r\n<p>Смешанные кризы проявляются сочетанием симптомов, типичных для преобладания тонуса симпатической или парасимпатической нервной системы, либо поочередным их появлением.</p>",
"image": null,
"image_alt": null,
"standard_type": 3,
"danger": 1,
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"description": "Ячмень (гордеолум) представляет собой острое гнойное воспаление волосяного мешочка или сальной железы края века. \r\n\r\nХалазион – доброкачественное опухолевидное уплотнение (градина) в толще века, развивающееся на фоне закупорки и хронического воспаления мейбомиевой железы.",
"etiology": "<p>Причиной гордеолума выступает бактериальная инфекция, в 90% наблюдений – золотистый стафилококк. В некоторых случаях первопричиной ячменя может являться микроскопический клещ демодекс, обитающий на ресницах, или грибки. Попаданию инфекции в волосяной фолликул и полость сальной железы способствует несоблюдения правил гигиены – вытирание лица грязным полотенцем, привычка тереть глаза руками, расчесывание век, использование некачественной косметики, загрязненных щеточек, аппликаторов для нанесения макияжа и т. д. </p>\r\n<p>Формирование халазиона происходит на фоне предшествующего ячменя, особенно в случаях неполного излечения или рецидива последнего. </p>\r\n<p>К развитию гордеолума и халазиона предрасполагает хронический блефарит, розацеа, жирная кожа, себорея, сахарный диабет, заболевания ЖКТ. Способствующими факторами могут выступать стрессы, переохлаждения, ОРВИ, гиповитаминозы, попадание инфекции в глаз при нарушениях правил личной гигиены, некорректном обращении с контактными линзами.</p>",
"pathogenesis": "<p>Проникновение микроорганизмов в полость сальной железы или волосяного мешочка приводит к закупорке выводного протока, открывающегося в фолликул, воспалению стенок полостей и скоплению гнойного секрета. </p>\r\n<p>Причиной развития халязиона служит закупорка протока мейбомиевой (сальной) железы века, в результате которой образуемый липидный секрет не имеет оттока наружу и скапливается в просвете протока железы. Этот механизм приводит к воспалению тканей вокруг железы, инкапсуляцией очага и образованию доброкачественного узелкового уплотнения на веке. <br class=\"SCXW72539199\" /> </p>",
"diagnostics": "<p>Диагностика гордеолума и халазиона проводится путем визуального осмотра глаза с выворотом век при боковом освещении. Дополнительная офтальмологическая диагностика в большинстве случаев не требуется. </p>",
"treatment": "<p>Лечение гордеолума включает инстилляции в конъюнктивальную полость раствора сульфацетамида или антибиотиков, закладывание глазных мазей с противомикробным действием. </p>\r\n<p>В стадии созревания ячменя показано применение сухого тепла, проведение физиотерапевтических процедур – тубус-кварц, УВЧ. </p>\r\n<p>После самопроизвольного прорыва ячменя продолжают инстилляции глазных капель и закладывание за веко антибактериальных глазных мазей. </p>\r\n<p>Лечение халазиона </p>\r\n<p>Хорошим лечебным эффектом обладают инъекции в халязион кортикостероидных препаратов. Кортикостероиды вводятся в полость халязиона тонкой иглой и приводят к постепенному рассасыванию новообразования. </p>\r\n<p>Радикальное лечение халязиона проводится хирургическим путем. Операция проводится под местной анестезией через трансконъюнктивальный или кожный разрез. В ходе операции халязион вылущивают вместе с капсулой. После удаления халязиона на веко накладывают швы, а на глаз - тугую давящую повязку. В послеоперационном периоде в течение 5-7 дней рекомендуется применение противовоспалительных глазных капель или мазей. </p>\r\n<p>Альтернативой классическому хирургическому методу служит лазерное удаление халязиона. </p>",
"prevention": "<p>Профилактика ячменя должна включать выявление и устранение предрасполагающих факторов, укрепление иммунитета, полноценное питание, соблюдение правил гигиены и требований ухода за контактными линзами, отказ от использования некачественной косметики и т. д. </p>\r\n<p>Для недопущения развития халязиона необходимо проведение полного объема лечения ячменя, блефарита, соблюдение требований гигиены при использовании контактных линз, повышение общей реактивности организма. </p>\r\n<p> </p>",
"clinical_picture": "<p>Развитие ячменя обычно происходит остро, в короткие сроки. Сначала появляется зуд края века, затем развивается гиперемия и локальная припухлость, которая сопровождается болью в покое и при надавливании на воспаленный очаг. Иногда отек века выражен настолько сильно, что пациент не может открыть глаз. Образование множественных ячменей на глазу сопровождается общими симптомами: повышением температуры тела, головной болью, недомоганием, припухлостью околоушных и подчелюстных лимфоузлов. </p>\r\n<p>Спустя 2-3 дня в области воспалительного фокуса появляется пустула – гнойная головка; одновременно с этим болевые ощущения стихают. При самостоятельном двскрытии ячменя из него выделяется гнойное содержимое, после чего все симптомы постепенно регрессируют. Обычно гнойно-воспалительный процесс при ячмене занимает около одной недели. </p>\r\n<p>Внутренний ячмень располагается изнутри века, в глубине хряща. Он определяется при выворачивании века как локальная гиперемия и отек конъюнктивы. Через 2-3 дня, по мере созревания ячменя, через слизистую просвечивает желтоватый гной. Самопроизвольное вскрытие внутреннего ячменя происходит со стороны конъюнктивы. В дальнейшем на слизистой оболочке века нередко разрастаются листовидные грануляции. </p>\r\n<p>При халазионе на веке прощупывается плотное образование размером с небольшую градину (горошину), кожа над ним приподнята, подвижна, со стороны конъюнктивы отмечается участок гиперемии (покраснения) и зона сероватого цвета в центре.Иногда происходит нагноение, тогда присоединяются признаки воспаления: боль, покраснение кожи век, может быть самопроизвольное вскрытие с выделением содержимого (гноя) со стороны конъюнктивы. </p>",
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"code": "H10",
"name": "Конъюнктивит",
"icd_name": "Конъюнктивит",
"gender": 0,
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"cause": [
1,
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"slug": "h10_konyunktivit",
"lead": "Нарушение здоровья, относящееся к группе болезни конъюнктивы",
"description": "Конъюнктивит – воспаление слизистой оболочки глаза (конъюнктивы), вызванное аллергией, бактериями, вирусами, грибами и другими патогенными факторами. ",
"etiology": "<p>Выделяют следующие причины развития конъюнктивита: </p>\r\n<ul>\r\n<li>Бактерии (пневмококковый, дифтерийный, диплобациллярный, гонококковый и др.);</li>\r\n<li>Хламидии (трахома, паратрахома);</li>\r\n<li>Вирусы (аденовирусный, герпетический, контагиозном моллюске и пр.);</li>\r\n<li>Грибки (при актиномикозе, споротрихозе, риноспородиозе, кокцидиозе, аспергиллезе, кандидозе и др.); </li>\r\n<li>Аллергия и аутоиммунные причины (при поллинозе, весеннем катаре, пузырчатке конъюнктивы, атопической экземе, демодекозе, подагре, саркоидозе, псориазе, синдроме Рейтера);</li>\r\n<li>Травмы (термические, химические);</li>\r\n<li>Метастатические конъюнктивиты при общих заболеваниях. </li>\r\n</ul>",
"pathogenesis": "<p>При инфекционном конъюнктивите возбудитель попадает в глаза контактно-бытовым или воздушно-капельным путем. При этом развивается воспалительный процесс, который состоит из нескольких этапов: </p>\r\n<ol>\r\n<li>Альтерация – повреждение, разрушение и частичная гибель клеток конъюнктивы под действием негативных факторов окружающей среды. </li>\r\n<li>Экссудация – окружение области повреждения лейкоцитами (клетки иммунной системы), которые выделяют соединения простагландины, инициирующие воспалительный процесс и оказывающие несколько основных биологических эффектов. К таким эффектам относится гиперемия (покраснение участка слизистой вследствие повышенного кровенаполнения), отек (выход плазмы крови в межклеточное пространство) и болевые ощущения (непосредственное раздражение чувствительных нервных окончаний простагландинами). </li>\r\n<li>Пролиферация – постепенное снижение воспалительной реакции с заменой поврежденных или погибших клеток новыми структурами, область значительной гибели клеток замещается соединительной тканью (фиброз). </li>\r\n</ol>\r\n<p>Эти фазы воспалительного процесса в конъюнктиве следуют в строгой очередности, независимо от причинного фактора, который привел к повреждению и разрушению клеток. </p>",
"diagnostics": "<p>При наружном осмотре выявляется гиперемия и отек конъюнктивы, инъекция глазного яблока, наличие отделяемого. </p>\r\n<p>Для установления причины конъюнктивита проводятся лабораторные анализы: цитологическое исследование соскоба или мазка-отпечатка, бактериологическое исследование мазка с конъюнктивы, определение титра антител (IgA и IgG) к предполагаемому возбудителю в слезной жидкости или сыворотке крови. </p>\r\n<p>При аллергическом конъюнктивите прибегают к проведению кожно-аллергических, назальной, конъюнктивальной, подъязычной проб.</p>",
"treatment": "<p>Для снятия симптомов вирусного конъюнктивита используются теплые компрессы и капли искусственной слезы. Специфическим противовирусным препаратом для лечения вирусных конъюнктивитов являются глазные капли, содержащие рекомбинантный интерферонтипа альфа 2. При присоединении вторичной бактериальной инфекции или для профилактики заражения воспаленной конъюнктивы, назначаются капли, содержащие антибиотики. </p>\r\n<p>При бактериальных конъюнктивитах используют глахные капли, содержащие антибиотик. </p>\r\n<p>Для лечения аллергического конъюнктивита используют антигистаминные препараты в форме капель для глаз и таблеток. Такие капли для глаз эффективны для снятия зуда, но могут вызвать покраснение глаз, отечность век. Такие капли в отличие от антигистаминных таблеток воздействуют быстрее и меньше способствуют сухости глаз. Помимо этого, уменьшить дискомфорт помогают капли искусственной слезы. В сложных случаях назначают нестероидные противовоспалительные препараты. </p>",
"prevention": "<p>Мероприятия, направленные на предотвращение развития конъюнктивита, включают исключение попадания чужеродных частиц, химических соединений и инфекции в глаза. Также необходимо контролировать время, проводимое за компьютером, просмотра телевизора или чтения книги для профилактики переутомления глаз, воздействия электромагнитного излучения и пересыхания слизистой оболочки. </p>",
"clinical_picture": "<p>Течение конъюнктивитов различного генеза характеризуется рядом общих признаков. К ним относятся: </p>\r\n<ul>\r\n<li>отечность и гиперемия слизистой век и переходных складок; </li>\r\n<li>выделение слизистого или гнойного секрета из глаз; </li>\r\n<li>зуд, жжение, слезотечение; </li>\r\n<li>ощущение «песка» или инородного тела в глазу; </li>\r\n<li>светобоязнь, блефароспазм (интенсивное смыкание век). </li>\r\n</ul>\r\n<p>Часто основным симптомом конъюнктивита служит невозможность разомкнуть веки по утрам ввиду их склеивания подсохшим отделяемым. При развитии аденовирусного или язвенного кератита возможно снижение остроты зрения. При конъюнктивитах, как правило, поражаются оба глаза: иногда воспаление возникает в них поочередно и протекает с разной степенью выраженности. </p>\r\n<p>Острый конъюнктивит манифестирует внезапно с боли и рези в глазах. Выражены инъекция (покраснение) глазных яблок, отек слизистой; из глаз выделяется обильный слизистый, слизисто-гнойный или гнойный секрет. При остром конъюнктивите часто нарушается общее самочувствие: появляется недомогание, головная боль, повышается температура тела. Острый конъюнктивит может продолжаться от одной до двух-трех недель. </p>\r\n<p>Подострый конъюнктивит характеризуется менее выраженной симптоматикой, чем острая форма заболевания. </p>\r\n<p>Развитие хронического конъюнктивита происходит постепенно, а течение носит упорный и длительный характер. Отмечаются дискомфорт и ощущения инородного тела в глазах, быстрая утомляемость глаз, умеренная гиперемия и рыхлость конъюнктивы, которая приобретает бархатистый вид. На фоне хронического конъюнктивита нередко развивается кератит. </p>\r\n<p>Аллергические конъюнктивиты, как правило, протекают с сильным зудом, болью в глазах, слезотечением, отеком век. </p>\r\n<p>Особенности клиники грибковых конъюнктивитов определяются видом грибка. При актиномикозе развивается катаральный или гнойный конъюнктивит; при бластомикозе – пленчатый с сероватыми или желтоватыми легко снимающимися пленками. Для кандидамикоза характерно образование узелков, состоящих из скопления эпителиоидных и лимфоидных клеток; аспергиллез протекает с гиперемией конъюнктивы и поражением роговицы. </p>\r\n<p>При конъюнктивитах, вызванных токсическими воздействиями химических веществ, возникают сильные боли при перемещении взгляда, моргании, попытке открыть или закрыть глаза. </p>\r\n<p>Основные симптомы развития блефароконъюнктивита: </p>\r\n<ul>\r\n<li>отёчность век и кожи вокруг глаза; </li>\r\n<li>покраснение глазного яблока; </li>\r\n<li>слезотечение; </li>\r\n<li>выделения гнойного или слизисто-гнойного характера; </li>\r\n<li>светобоязнь; </li>\r\n<li>жжение и зуд в глазах. </li>\r\n</ul>",
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},
"code": "H16",
"name": "Кератит",
"icd_name": "Кератит",
"gender": 0,
"age_min": 1,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "h16_keratit",
"lead": "заболевание роговой оболочки глаза воспалительного характера, проявляющееся преимущественно болью и покраснением глаза, помутнением и изъязвлением роговицы",
"description": "<p><span id=\"docs-internal-guid-d622b4ee-7fff-e7b3-1602-de4b76c0153c\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Кератит — это воспалительное заболевание роговицы, которое характеризуется ее помутнением, а также ухудшением зрения.</span></span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">На появление патологии могут повлиять различные факторы, которые условно можно разделить на внешние и внутренние. В одной ситуации кератит будет развиваться как самостоятельное заболевание (экзогенная группа кератитов), в другом — как осложнение общего заболевания организма (эндогенная группа кератитов).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основные внешние факторы:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Бактерии — пневмококки, стрептококки, стафилококки; гемофильная, синегнойная и кишечная палочки и т. п.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Вирусы — простой герпес, аденовирус, корь и т. д.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Грибы — аспергиллы, плесневые грибки, фузарии, кандиды и т. п.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Простейшие организмы — токсоплазмы, лейшмании, глисты, амебы и т. п.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Механические и термические травмы глаза и, в частности, роговицы.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Несоблюдение гигиены глаз (прикасание грязными руками, неправильное использование контактных линз и прочее).</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основные внутренние факторы:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Аллергические процессы (аллергический ринит, медикаментозная аллергия и т. д.).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Аутоиммунные заболевания (синдром Шегрена, ревматоидный артрит и т. д.).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Офтальмологические заболевания (дистрофия роговицы, блефарит, конъюнктивит и т. д.).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Патологии при нарушении обменных процессов (сахарный диабет, псориаз и т. д.).</span></li>\r\n</ul>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В роговой оболочке появляются отек и инфильтраты. Инфильтраты состоят преимущественно из лимфоидных клеток, полинуклеарных лейкоцитов и небольшого количества плазматических клеток, а также из измененных клеток стромы роговицы. Эпителий над инфильтратами может отслаиваться и слущиваться, появляются эрозии, роговица становится шероховатой и теряет свой блеск. После развития инфильтрата или одновременно с ним из конъюнктивы и склеры в роговую оболочку врастают поверхностные и глубокие сосуды. Небольшие поверхностные инфильтраты обычно рассасываются бесследно, глубокие - оставляют помутнения различной выраженности.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При осложнении гнойной инфекцией инфильтраты протекают с некрозом ткани роговицы и обычно изъязвляются. Язвенный дефект в дальнейшем заполняется рубцовой тканью, образуя лейкому.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для того, чтобы диагностировать заболевание на ранней стадии, определить очаг поражения, проводят:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">бактериологическое исследование</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">бактериоскопическое исследование</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">биомикроскопию</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">зеркальную микроскопию заднего эпителия роговицы</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">иммунологические исследования</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">кожно-аллергические пробы</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">пробу с флюоресцеином</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">цитологическое исследование эпителия конъюнктивы и роговицы</span></li>\r\n</ul>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для корректного назначения лечения заболевания важно определить причину его возникновения. Так при инфекционных (бактериальном, вирусном и грибковом) кератитах назначают антибактериальную, противовирусную или противогрибковую терапию; при аллергических ­— антигистаминные и гормональные препараты и т. д. Точную схему лечения может разработать только специалист после проведения обследования.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При этом лечение может состоять из медикаментозной терапии в виде использования глазных капель и мазей, таблеток или внутривенных инъекций, а также хирургического лечения — кератопластика (трансплантация роговицы), лазерокоагуляция (шлифовка роговицы) и т. д. Операции проводятся только в том случае, если консервативные методы не дали положительного результата.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика кератита заключается, во-первых, в предупреждении травм (в т.ч. микротравм) глаза. При выполнении различных работ (электросварка, резка металла и дерева электроинструментом, работа с химикатами и др.) следует пользоваться защитными очками. Так же следует обращать внимание на здоровье своих глаз: своевременно обращаться к врачу и проводить лечение блефарита, конъюнктивита, дакриоцистита, иммунодефицитных состояний и различных заболеваний, способствующих развитию эндогенного кератита.</span></p>",
"clinical_picture": "<ul>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Болевые ощущения в глазах. Это наиболее распространенное проявление заболевания: человек чувствует резь, покалывания, возникает ощущение, что в глазах есть инородное тело.</span></li>\r\n<li><span style=\"background-color: transparent; font-size: 7pt; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Покраснение склеры. Глаза краснеют, роговица становится тусклой.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Светобоязнь. Яркий свет вызывает болезненные ощущения.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Слезоточивость.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Непроизвольное смыкание век (рефлекторный блефароспазм).</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Пониженная чувствительность роговицы.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При осмотре офтальмолог может заметить на роговице следы крови или лимфы. Из-за этих инфильтратов острый кератит может вызвать рубцевание ткани: это негативно скажется на зрении и может привести к необходимости операции.</span></p>",
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}
]
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