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},
"code": "O40",
"name": "Многоводие",
"icd_name": "Многоводие",
"gender": 2,
"age_min": 15,
"age_max": 50,
"cause": [
"0"
],
"periodicity": 1,
"slug": "o40_mnogovodie",
"lead": "состояние, для которого характерно увеличение количества околоплодных вод в амнионе",
"description": "",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Многоводие не заболевание, а симптом различных патологических процессов, протекающих в организме матери и плода, поэтому причины его возникновения многочисленны.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Причины со стороны беременной: сахарный диабет, перенесенные инфекции, несовместимость крови плода и матери, порок сердца, сифилис, нефрит, тяжелая анемия.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Осложнения беременности: трансфузионный синдром (при многопладной беременности), гестоз.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Плацентарные причины: патология плаценты (хорионангиома), фетоплацентарная дисфункция, характеризующаяся снижением всасывания околоплодных вод и увеличением их продукции.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Со стороны плода отмечаются различные пороки развития: атрезия пищевода или кишечника на разных уровнях, диафрагмальная грыжа, болезнь Гиршпрунга, анэнцефалия, микроцефалия, опухоли, тяжелые пороки сердца, генетическая патология, миастения, почечная обструкция, гипоплазия легких, внутриутробное инфицирование краснухой, токсоплазмозом, сифилисом. Предполагается, что при анэнцефалии или микроэнцефалии снижается выработка антидиуретического гормона, что вызывает полиурию (обильное мочеиспускание) у плода и увеличение количества вод. При анэнцефалии, миастении и пороках ЖКТ нарушается глотание плодом вод, что ведет к их повышенному накоплению.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Многоплодная беременность.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Большую роль в развитии этой патологии играют вирусные и бактериальные инфекции, которые и составляют основные причины на поздних сроках, независимо от того, когда женщина перенесла вирусную инфекцию (грипп, ОРВИ, вирус простого герпеса) или воспалительные заболевания половой системы. Внутриутробную инфекцию у плода вызывают урогенитальный микоплазмоз матери, уреаплазмоз, хламидиоз, бактериальный вагиноз, кандидоз. У плода может наблюдаться не только острая, но и медленно текущая хроническая инфекция.</span></p>\r\n<p><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основную роль в развитии многоводия играет плацента и плодные оболочки. При этой патологии выявляют инволютивные изменения в плаценте и амнионе. В плодных оболочках увеличивается число микроворсинок и их усиленное ветвление, что сопровождается увеличением толщины зародышевой оболочки. При данной патологии, с одной стороны, усиливается секретирующая активность эпителия амниона, а с другой — происходят деструктивные изменения в нем, которые ведут к некрозу ткани. Некроз влияет на развитие плода и вызывает различные патологии развития. Изменения претерпевают и вены хориона — они сужаются, а иногда в ворсинах хориона они полностью зарастают. При многоводии через оболочки и через расширенные межклеточные каналы в эпителии увеличивается транспорт жидкости внутрь. А за счет утолщения плодных оболочек частично блокируется обратное всасывание вод, что способствует увеличению их количества.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заподозрить многоводие при беременности акушер-гинеколог может уже на основании объективного осмотра и жалоб пациентки. Помимо ухудшения общего состояния женщины характерным признаком является увеличение стояния дна матки, не соответствующее сроку гестации. Также о многоводии при беременности свидетельствует значительное увеличение окружности живота, показатели порой превышают 100-120 см. При пальпации может определяться патологическое положение плода в маточной полости – косое, поперечное или тазовое. При подозрении на многоводие при беременности женщине назначается лабораторная диагностика: общие анализы крови и мочи, мазок из половых путей на микрофлору с целью обнаружения инфекций.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если многоводие при беременности вызвано резус-конфликтом, показано исследование на определение количества антител. Диагноз окончательно устанавливается после проведения УЗИ. В ходе процедуры удается измерить количество ОПВ, а также оценить функциональность плаценты и самочувствие плода. В редких случаях осуществляется амниоцентез. Многоводие при беременности требует тщательного наблюдения за малышом. С этой целью проводятся КТГ и маточно-плацентарная допплерография, позволяющие оценить степень гипоксии, работу сердца, двигательную активность, уровень кровотока в сосудах пуповины и определиться с дальнейшей врачебной тактикой.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Многоводие при беременности требует госпитализации в акушерский стационар и тщательного наблюдения за состоянием женщины и плода. Назначается полный покой, важно исключить стрессовые факторы и физические нагрузки. Медикаментозное лечение многоводия при беременности зависит от причины возникновения данного состояния. Обязательно осуществляется терапия основного заболевания, которое способствовало развитию патологического увеличения объема ОПВ. Если этиология многоводия при беременности не установлена, применяется классическая схема – антибактериальная терапия с целью предупреждения занесения внутриутробной инфекции.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Консервативное лечение многоводия при беременности также предполагает использование препаратов для улучшения маточно-плацентарного кровотока, витаминных комплексов, мочегонных лекарственных средств. В случае острого многоводия при беременности и значительного ухудшения состояния пациентки, сопряженного с угрозой для ее жизни, в зависимости от срока эмбриогенеза показано прерывание или преждевременное родоразрешение путем кесарева сечения. Если консервативный подход дает положительную динамику, ведение беременности продолжают до 37-38 недель.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Родоразрешение в случае многоводия при беременности проводится с помощью планового кесарева сечения. Важно предупредить самопроизвольное вскрытие плодного пузыря. Из-за большого объема амниотической жидкости ее стремительное излитие может привести к выпадению мелких частей плода, а также слабости родовой деятельности. Если принято решение об осуществлении естественных родов на фоне многоводия при беременности, требуется проведение амниотомии. Это дополнительно стимулирует схватки.</span></p>",
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},
"code": "O73",
"name": "Задержка плаценты и плодных оболочек без кровотечения",
"icd_name": "Задержка плаценты и плодных оболочек без кровотечения",
"gender": 2,
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0
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"slug": "o73_zaderzhka_placenty_i_plodnyh_obolochek_bez_krovotecheniya",
"lead": "Плотное прикрепление — прикрепление плаценты в базальном слое слизистой оболочки матки. Приращение плаценты — врастание плаценты в мышечный слой матки.\r\n\r\n",
"description": "Плотное прикрепление — прикрепление плаценты в базальном слое слизистой оболочки матки. Приращение плаценты — врастание плаценты в мышечный слой матки.\r\n\r\n",
"etiology": "<p>В норме плацента формируется в функциональном слое слизистой оболочки, который трансформируется вдецидуальный. Отделение плаценты от стенки матки в третьем периоде родов происходит на уровне губчатого слоя децидуальной оболочки.</p>\r\n<p>При воспалительных заболеваниях или дистрофических изменениях эндометрия губчатый слой подвергаетсярубцовому перерождению, вследствие чего самостоятельное отделение ткани вместе с плацентой в третьем периоде родов невозможно. Указанное состояние называют плотным прикреплением. При атрофии функционального и базального слоя слизистой оболочки один или несколько котиледонов формирующейся плаценты доходят до мышечного слоя или прорастают в него (истинное врастание).</p>\r\n<p>К патологическому прикреплению плаценты приводят либо изменения слизистой матки, либо особенности хориона. К изменениям слизистой матки, способствующим нарушению формирования трофобласта, приводят следующие заболевания:</p>\r\n<p>· неспецифические и специфические воспалительные поражения эндометрия (хламидиоз, гонорея, туберкулёз и т.д.);<br />· чрезмерное выскабливание во время удаления плодного яйца или диагностических манипуляций;<br />· послеоперационные рубцы на матке (кесарево сечение и миомэктомия).</p>\r\n<p>Нарушение отделения плаценты и выделения последа может быть обусловлено местом прикрепления плаценты: в нижнем маточном сегменте (при низком расположении и предлежании), в углу или на боковых стенках матки, наперегородке, над миоматозным узлом. В указанных местах мускулатура неполноценна и не может развить силысокращений, необходимой для отделения плаценты.</p>",
"pathogenesis": "",
"diagnostics": "<p>Точно определить вариант патологического прикрепления плаценты можно при целенаправленном УЗИ и ручномотделении плаценты. При УЗИ для врастания плаценты характерно следующее:<br />· расстояние между серозной оболочкой матки и ретроплацентарными сосудами менее 1 см;<br />· наличие большого количества интраплацентарных гиперэхогенных включений или кист.</p>",
"treatment": "<p>При ручном отделении плаценты при плотном её прикреплении, как правило, можно рукойудалить все доли плаценты. При истинном врастании ворсин хориона невозможно отделить плаценту от стенки без нарушения её целостности.</p>\r\n<p>Нередко истинное врастание плаценты устанавливают только при гистологическом исследовании матки, удалённой в связи с предполагаемой гипотонией и массивным кровотечением в послеродовом периоде.</p>",
"prevention": "<p>Профилактика патологического прикрепления плаценты состоит в снижении частоты абортов, воспалительныхзаболеваний, приводящих к дистрофическим изменениям слизистой матки.</p>\r\n<p> </p>\r\n<p> </p>\r\n<p> </p>",
"clinical_picture": "<p>Клиническая картина нарушения отделения плаценты и выделения последа зависит от наличия участковотделившейся плаценты. Если плацента не отделяется на всём протяжении (полное патологическое прикрепление), клинически определяют отсутствие признаков отделения плаценты и отсутствие кровотечения.</p>\r\n<p>Чаще наблюдают частичное отделение плаценты (неполное прикрепление), когда тот или иной участок отделяется от стенки, а остальная часть остаётся прикреплённой к матке. В указанной ситуации <a href=\"/symptom/neproizvolnye_dvizheniya/\" title=\"Перейти на страницу симптома Непроизвольные движения\">сокращение мышц</a> на уровне отделившейся плаценты недостаточно для того, чтобы пережать сосуды и остановить <a href=\"/symptom/krovotechenie/\" title=\"Перейти на страницу симптома Кровотечение\">кровотечение</a> из плацентарной площадки. Основные симптомы при частичном отделении плаценты — отсутствие признаков отделения плаценты и <a href=\"/symptom/krovotechenie/\" title=\"Перейти на страницу симптома Кровотечение\">кровотечение</a>.</p>\r\n<p><a href=\"/symptom/krovotechenie/\" title=\"Перейти на страницу симптома Кровотечение\">Кровотечение</a> из плацентарной площадки возникает через несколько минут после рождения ребёнка. Кровь жидкая, с примесью сгустков различной величины, вытекает толчками, неравномерно.</p>",
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