Disease List

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            "code": "C69.2",
            "name": "Рак сетчатки",
            "icd_name": "Рак сетчатки",
            "gender": 0,
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            "lead": "злокачественная опухоль глаза, развивающаяся преимущественно в детском возрасте из тканей эмбрионального происхождения",
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            "etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Среди причин развития ретинобластомы принято выделять наследственные и внешние факторы. При этом, в соответствии с причиной, определяют 2 формы заболевания:</span></p>\r\n<p>&nbsp;</p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Наследственная ретинобластома составляет примерно 60-70% случаев и носит генетический характер. У родителей, в детстве болевших ретинобластомой, дети тоже рождаются с этим недугом. Данная форма заболевания развивается достаточно быстро, как правило, поражая оба глаза, и со временем, проникая в ближайшие ткани. Наследственную ретинобластому, обычно сопровождает множество других пороков развития, таких как кортикальный детский гиперостоз, расщелина нёба, пороки сердца и предрасположенность к возникновению опухолей в остальных тканях и органах.</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Спорадическая ретнобластома возникает случайно, как результат неблагоприятного воздействия экологической среды и генномодифицированных продуктов. В случае этой формы заболевания, поражается обычно только один глаз. Проявляется спорадическая опухоль намного позже наследственной и лечится проще.</span></li>\r\n</ul>",
            "pathogenesis": "",
            "diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для оценки распространенности опухоли, назначаются следующие диагностические исследования:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Магнитно-резонансная и компьютерная томография пораженного глаза (глаз).</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Пункция головного мозга (с целью выявления степени поражения);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Рентген легких;</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">УЗИ брюшной полости (с целью выявления очагов метастаз);</span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Анализ мочи и крови (с целью оценки работы внутренних органов).</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">У детей ретинобластома нередко сопровождается сбоями функций других органов, поэтому в комплекс диагностических мероприятий включают консультации с неврологом и ЛОР-врачом.</span></p>",
            "treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">План лечения разрабатывается врачом в зависимости от стадии ретинобластомы. Если имеется двустороннее поражение, тактику лечения разрабатывают для каждого глаза отдельно.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В ходе лечения может быть использовано несколько разных методов, их правильное сочетание во многом определяет шансы на сохранение зрения и глаза. Современные методы диагностики позволяют выявить ретинобластому на ранней стадии, когда для успешного лечения еще достаточно криотерапии, фотокоагуляции и лучевого воздействия.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Методы лечения ретинобластомы:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">хирургическое вмешательство;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">лучевая химиотерапия;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">лекарственная химиотерапия;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">криотерапия;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">лазерная коагуляция;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">термотерапия.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Современная медицина предпочитает консервативное лечение ретинобластомы. Такая тактика эффективна только при наличии небольших единичных образований, которые остаются в пределах глаза, но за границами макулярной и перипапиллярной зон.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для лечения рака глаза активно применяют криотерапию и фотокоагуляцию, позволяющие сохранить зрение и редко дающие осложнения. Криотерапия воздействует на поражения в передней камере глазного яблока, а фотокоагуляция &ndash; в задней. Контроль за ходом лечения осуществляют при помощи офтальмоскопии и ультразвукового исследования.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Методы локального лечения ретинобластомы:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Брахитерапия. Техника локального облучения опухолей, которая заключается в подшивании к глазу офтальмоаппликатора (радиоактивная пластинка). Преимущество метода заключается в том, что можно подводить максимальные дозы излучения непосредственно к очагу без воздействия на здоровые ткани глаза и организм.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Криодеструкция. Метод воздействия низкими температурами. При замораживании клетки опухоли перестают расти и разрушаются. Лечение осуществляют при помощи аппарата с наконечником в несколько миллиметров. Криодеструкция применима к опухолям в переднем отделе сетчатки, которые не превышают 7 мм в диаметре.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Фотокоагуляция. Лечение с применением лазерного луча. Эффективно при размерах ретинобластомы до 4 мм и расположении в заднем отделе сетчатки.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Транспупиллярная диод-лазерная термотерапия (ТТТ). Бесконтактное лечение внутриглазных опухолей, основанное на инфракрасном излучении. Метод заключается в длительном прогревании ретинобластомы до 45-55&deg;С.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>",
            "prevention": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Поскольку в подавляющем большинстве случаев заболевание имеет врожденную природу, профилактикой будет генетическое консультирование семей, в которых были случаи рака сетчатки. Очень важно регулярно обследовать детей из групп риска и соответствующих по возрасту.</span></p>",
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            "code": "C71",
            "name": "Рак головного мозга",
            "icd_name": "Рак головного мозга",
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            "age_min": 1,
            "age_max": 100,
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            "description": "Опухоль мозга сильно отличается от других видов новообразований и составляет примерно 2% от всех случаев раковых болезней. Из-за неудобства расположения, симптомы заболевания трудно поддаются действенному диагностированию и удалению, что осложняет возможность их лечения. ",
            "etiology": "<ol>\r\n<li>Генетика: некоторые заболевания являются катализатором рака на протяжении жизни. Например, синдром Туркота или синдром Ли-Фраумени, а также синдром Горлина или болезнь фон Хиппель-Ландау.</li>\r\n<li>Облучение головы, ствола, мозжечка – к сожалению, лечение от одной болезни, например, рака крови или лейкемии, может привести к развитию другой, рака мозга. Люди, которые живут в регионах с неблагоприятным радиоактивным фоном, имеют в несколько раз больший риск носить в себе опухоль.</li>\r\n<li>Наличие вирусов в крови, инфекций ствола.</li>\r\n<li>Влияние электромагнитных импульсов: сколько уже выпущено публикаций на эту тему – воздействие мобильных телефонов и других устройств на появление рака и продолжительность жизни в целом. Впрочем, научных доказательств, более-менее убедительных, пока не представлено.</li>\r\n<li>Вторично опухоль развивается практически во всех случаях ввиду наличия рака в другой части тела.</li>\r\n<li>Перенесенные травмы мозга, сотрясения ствола.</li>\r\n<li>Вредная нагрузка – работа в условиях химических выбросов и т.п.</li>\r\n<li>Курение и злоупотребление алкоголем.</li>\r\n</ol>",
            "pathogenesis": "",
            "diagnostics": "<p>Чтобы помочь классификации опухолей головного мозга, выявить ее локализацию, размеры, природу, врачи назначают такое обследование, как магниторезонансная томография. Либо компьютерная томография – часто их сочетают, чтобы понять, расположена ли опухоль в отделе ствола или корковых слоях, или раковые клетки распространились на другие доли.</p>\r\n<p>Также с целью выявления развития заболевания на поздних стадиях требуется анализ взятого «кусочка» опухоли, для чего проводят стереотаксическую биопсию, внедряясь в область головного мозга с помощью тонкой иглы.</p>",
            "treatment": "<p>Для лечения обычно выбирается комплекс мероприятий, среди которых: хирургическое вмешательство, лучевая терапия, радиохирургия, химиотерапия, криохирургия, а также проводится симптоматическая терапия, направленная на облегчение состояния больного, купирование болевого синдрома и снятие отёка головного мозга.</p>",
            "prevention": "",
            "clinical_picture": "<ul>\r\n<li>Сильная <a href=\"/symptom/golovnaya_bol/\" title=\"Перейти на страницу симптома Головная боль\">головная боль</a> – при возникновении опухоли в конкретной доле мозга, стволе или в области гипофиза концентрируется именно там. Боль может усиливаться при кашле, чихании, резких усилиях, а также часто появляется у взрослых под утро после сна.</li>\r\n<li><a href=\"/symptom/toshnota/\" title=\"Перейти на страницу симптома Тошнота\">Тошнота</a> и <a href=\"/symptom/rvota/\" title=\"Перейти на страницу симптома Рвота\">рвота</a> – присутствуют у малышей в виде частых срыгиваний. У взрослых на последних стадиях рака может наблюдаться и <a href=\"/symptom/krovavaya_rvota/\" title=\"Перейти на страницу симптома Кровавая рвота\">кровавая рвота</a>.</li>\r\n<li><a href=\"/symptom/golovokruzhenie/\" title=\"Перейти на страницу симптома Головокружение\">Головокружение</a> – также относится к симптомам опухоли головного мозга, если возникает в любом положении и долго не проходит. Объясняется изменениями гипофиза или вестибулярного аппарата, а также повышением внутричерепного давления.</li>\r\n<li>Ватность суставов и конечностей. На 1й стадии проявляется только как <a href=\"/symptom/slabost/\" title=\"Перейти на страницу симптома Слабость\">слабость</a>, на последних рак может приводить к параличу или частичному парезу конечностей. Так как отказывают те центры головного мозга, которые отвечают за движение и координацию у взрослых. Большинство из них расположено, кстати, в районе гипофиза.</li>\r\n<li>Проблемы со зрением – первые признаки рака мозга проявляются в ухудшении зрения без причин, появлении звездочек и пятен перед глазами, болезненности глазного нерва. Может проявляться <a href=\"/symptom/nistagm/\" title=\"Перейти на страницу симптома Нистагм\">нистагм</a> глазного яблока уже на 1-2 стадии.</li>\r\n<li>Проблемы со слухом – <a href=\"/symptom/shum_v_ushah/\" title=\"Перейти на страницу симптома Шум в ушах\">звон в ушах</a> или <a href=\"/symptom/snizhenie_sluha/\" title=\"Перейти на страницу симптома Снижение слуха\">глухота</a> одностороннего характера говорит о давлении опухоли головного мозга на сосуды или систему слухового аппарата.</li>\r\n<li>Эпилептические припадки – появляются не у всех, а лишь в 5-10% случаев, да и то далеко не на 1й стадии.</li>\r\n</ul>",
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