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"name": "Дискинезия пищевода",
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"lead": "расстройство продвижения пищевого комка из глотки в желудок, не связанное с органическим поражением пищеводной стенки",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дискинезии пищевода - это нарушения его моторной (двигательной) функции, заключающиеся в изменении продвижения пищи из полости глотки в желудок при отсутствии органических поражений пищевода.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дискинезия пищевода может развиться первично (при отсутствии другой патологических процессов) либо вторично - на фоне заболеваний пищевода (эзофагиты, грыжа пищеводного отверстия диафрагмы, дивертикулы и рак пищевода) и других органов (системные заболевания соединительной ткани, сахарный диабет, тяжелая патология нервной системы, язвенная болезнь желудка, хронический холецистит), приема некоторых лекарственных препаратов.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нарушение моторики и формирование первичной дискинезии пищевода происходит в результате воздействия стрессов, сбоев в развитии мышечной оболочки и нервного аппарата пищевода. В результате этих причин возникает дискоординация нервной и гуморальной регуляции сокращения стенки пищевода, развивается двигательная дисфункция.</span></p>",
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"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Консультация врача-гастроэнтеролога и эндоскописта требуется всем пациентам с подозрением на дискинезию пищевода. Наиболее информативным методом диагностики является рентгеноскопия пищевода. На гипермоторную дискинезию во время исследования указывают зубчатые контуры пищеводной стенки, задержка прохождения контраста более 5 сек., локальные деформации, неперистальтические сокращения пищевода при глотании; на другие виды дискинезии - спазм сфинктеров, отсутствие газового пузыря желудка (при ахалазии кардии).</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эзофагеальная манометрия выявляет спастические сократительные волны в пищеводе с повышением давления более 30 мм. рт. ст., неполную релаксацию нижнего сфинктера, эпизоды нормальной перистальтики (дифференцируют спазм пищевода и ахалазию кардии). Эзофагоскопия, анализ кала на скрытую кровь используются для выявления осложнений дискинезии пищевода и сопутствующих заболеваний. Эндоскопическое исследование может провоцировать усиление болей за грудиной, не несет большой информационной нагрузки.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для лечения широко используется диета – частое дробное питание небольшими порциями. Пища должна быть термически, механически и химически щадящей, исключаются продукты с высоким содержанием клетчатки. Следует избегать физических нагрузок, нагибания, переедания.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Из медикаментов, нормализующих моторику пищевода и обладающих спазмолитическим действием, назначают блокаторы кальциевых каналов, антихолинолитики, нитраты. Широкое применение нашли и седативные средства. Проводится лечение осложнений дискинезии (ГЭРБ, эзофагитов). Хирургическое вмешательство показано только при неэффективности консервативного и тяжелых формах заболевания.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика заключается в регулярном прохождении медосмотров, своевременной терапии заболеваний, которые могут привести к дискинезии пищевода.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Наиболее распространёнными симптомами, сопровождающими спазм пищевода, являются:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">острая загрудинная боль, напоминающая приступ стенокардии;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">дисфагия (затруднённое глотание);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">одинофагия (болезненное глотание);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">жжение за грудиной;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">регургитация (возврат содержимого желудка в полость рта);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">болезненная обструкция с ощущением застревания.</span></li>\r\n</ul>",
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},
"code": "L93.0",
"name": "Дискоидная красная волчанка",
"icd_name": "Дискоидная красная волчанка",
"gender": 0,
"age_min": 1,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 3,
"slug": "l93.0_diskoidnaya_krasnaya_volchanka",
"lead": "хроническое воспалительное аутоиммунное заболевание кожи, развивающееся на фоне фотосенсибилизации (повышенной чувствительности к свету)",
"description": "",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Точно выявить механизм возникновения болезни пока нельзя. Но считается, что наиболее подвержены волчанке люди, проживающие во влажном климате с холодной зимой.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Несмотря на то, что точная причина дискоидной красной волчанки до сих пор не определена, известны факторы, которые способствуют развитию болезни и её обострению:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">травматизация кожи;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">воздействие ультрафиолета;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">прием некоторых медикаментов;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">наследственные факторы;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">инфекционные заболевания;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">воздействие на кожу низких температур;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">болезнь Рейно.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Наиболее часто развитие заболевания сопряжено с воздействием солнечного или искусственного ультрафиолетового облучения, а также с чрезмерным охлаждением кожи или обморожениями. В таких случаях патология возникает на поврежденных участках кожных покровов.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ультрафиолетовые лучи и инфекции угнетают защитные функции организма, вызывая выделение иммунных частиц на поверхность, и под их воздействием начинает формироваться заболевание. Почти 50% людей, страдающих волчанкой, являются светочувствительными.</span></p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При дискоидной красной волчанке наблюдается патогенетическое сходство с СКВ, однако патологические реакции ограничиваются кожными покровами. В основе заболевания лежит аутоиммунное воспаление. Под действием ультрафиолетовых лучей в совокупности с другими провоцирующими факторами в клетках кожи нарушаются процессы метилирования ДНК (механизма регуляции транскрипции генов). Это приводит к повышению экспрессии белков, индуцирующих апоптоз (запрограммированную клеточную гибель).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Т- и В-лимфоциты стимулируют синтез цитокинов и антител к компонентам клеточных ядер (нуклеиновым кислотам, нуклеосомам). Образующиеся иммунные комплексы оседают на эндотелии сосудов, вызывая их повреждение. Выработку аутоантител у генетически предрасположенных лиц также способны вызывать антигены некоторых вирусов (Эпштейна-Барр, цитомегаловирус, парвовирус 19), имеющие сходную молекулярную структуру с белками клеточных мембран. Дополнительным повреждающим агентом выступает индукция свободнорадикального окисления липидов. Результатом этих процессов является массивное воспаление и разрушение клеток кожи.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заболевание необходимо дифференцировать от псориаза, экземы, красных комедонов, саркоидоза, красного лишая, розовых угрей, себорейного дерматита и других кожных болезней. Для этого необходимо провести диагностику. Определяется волчанка по внешнему виду пораженной кожи, а также по результатам лабораторных и инструментальных исследований, таких как:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Гистология ткани. Для ее проведения берут часть кожи и проводят анализ под микроскопом. Делают его от 5 до 10 дней. </span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Исследование</span><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\"> волос и чешуек кожи под микроскопом. </span></li>\r\n<li><span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">Иммунофлюоресцентный метод исследования биоптата кожи на волчанку. </span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При этом лабораторные анализы крови и мочи каких-либо отклонений, позволяющих выявить заболевание, не обнаруживают.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В большинстве случаев пациенты проходят лечение амбулаторно, но при тяжелом течении может потребоваться госпитализация в отделение ревматологии или дерматологии. Важным моментом является исключение приема фотосенсибилизирующих медикаментов и лечение сопутствующих аллергических или инфекционных заболеваний. Рекомендуется носить закрытую одежду, применять солнцезащитные крема или мази, содержащие вещества, которые задерживают ультрафиолетовые лучи (мексорил, двуокись титана, оксид цинка).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основное патогенетическое лечение включает антималярийные аминохинолиновые препараты (Гидроксихлорохин), топические глюкокортикостероиды (тГКС), производные витамина А - ретиноиды (Изотретиноин, Ацитретин). Ввиду частого развития ретинопатий на фоне приема гидроксихлорохина обязателен регулярный осмотр офтальмолога. В зависимости от локализации дискоидных очагов применяются тГКС разной активности. При расположении очагов только на коже лица используют тГКС слабой и средней степени активности (Гидрокортизона ацетат, Метилпреднизолон), при поражении кожи конечностей и туловища рекомендуются тГКС сильной активности (Бетаметазон, Триамцинолон). Если дискоидные очаги имеются на ладонях и подошвах, назначаются тГКС сверхвысокой активности (Клобетазон).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для подавления свободнорадикального повреждения клеток кожи эффективны антиоксиданты (альфа-токоферол). При неэффективности стандартного лечения прибегают к средствам, обладающим выраженным иммуносупрессивным действием – Такролимус, Метотрексат, Азатиоприн.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Профилактика дискоидной волчанки заключается в ограничении времени пребывания на солнце, ношении закрытой одежды, применении солнцезащитных препаратов, исключении приема лекарств, повышающих чувствительность кожных покровов к ультрафиолетовому излучению.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В большей части случаев болезнь начинается с лица. На коже в зонах носа и щек появляются красно-розовые пятна, которые постепенно приобретают плотность и покрываются у основания волосяных фолликулов небольшими чешуйками. Их удаление сопровождается болью. Обнаженная кожа напоминает лимонную кожуру. С развитием болезни появляются следующие симптомы:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">зуд, жжение;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">краснота (эритема);</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отеки тканей (инфильтрация);</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">расширение площади поражения;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">сосудистые звездочки (телеангиоэктация);</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">истончение кожи (инволюция);</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">утолщение рогового слоя эпидермиса (гиперкератоз).</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В местах поражения выпадают волосы. Пятна распространяются на ушные раковины и слизистую рта, грудь, живот, плечи, поясницу, пальцы. Пораженные участки могут атрофически изменяться, пятна заменяются на белые рубцы либо образования другого цвета. Иногда болезнь затрагивает не только кожу, но и:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">суставы;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">мышцы;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">глаза.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Процесс нарушает работу некоторых органов и систем организма. Формируется волчаночный артрит, в основном, кистей рук. Патологические клетки могут быть обнаружены даже в костном мозге человека. Замечено, что недуг нарушает работу:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">половой системы;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">эндокринных желез;</span></li>\r\n<li><span style=\"font-size: 7pt; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">коры надпочечников.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В результате описанных признаков, у больного часто наблюдается угнетение нервно-психического состояния, что приводит к депрессии. Все описанные симптомы могут выражаться неодинаково, на что влияет уровень иммунной системы больного и длительность заболевания.</span></p>",
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},
"code": "N94.1",
"name": "Диспареуния",
"icd_name": "Диспареуния",
"gender": 2,
"age_min": 16,
"age_max": 70,
"cause": [
"0"
],
"periodicity": 1,
"slug": "n94.1_dispareuniya",
"lead": "болевые ощущения в области половых органов, испытываемые во время полового акта",
"description": "",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Физические причины диспареунии</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Боли, провоцируемые половым контактом, могут возникать при воспалительных патологиях малого таза, при хронических инфекциях, травмах, опухолях, кистах, эндометриозе. После излечения основного заболевания симптомы проходит самостоятельно.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Заболевания женской половой сферы, сопровождающиеся диспареунией:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инфекционные заболевания: бактериальные и грибковые поражения преддверия влагалища (вульвиты), влагалища (вагиниты), шейки матки (цервициты, эндоцервициты), придатков матки (сальпингоофориты, аднекситы), в т.ч. инфекции, передающиеся половым путём;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инфекции мочевыводящего тракта (воспаление мочеиспускательного канала, мочевого пузыря);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эндометриоз (аденомиоз);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">* Эрозия (эктопия) шейки матки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Гормональные нарушения (дефицит женских половых гормонов);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Миома;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кисты яичников;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Травмы (родовые, хирургические);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Доброкачественные и злокачественные опухоли;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Врождённые пороки развития женских половых органов;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Патологии мышц тазового дна.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При любой из вышеперечисленных патологий половой акт способен провоцировать появление болевого синдрома, вплоть до полного неприятия любых видов сексуальной активности.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Психологические факторы диспареунии</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Психологические (психические) расстройства, такие как депрессия, неврозы, тревожные состояния и фобии оказывают значительное влияние на сексуальную активность, способствуя снижению либидо и степени сексуального возбуждения. Эта связь может приводить к различным сексуальным расстройствам, таким как вагинизм (спазм мышц влагалища, препятствующий вагинальному контакту) и диспареуния.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В нормальных условиях половой акт состоит из прелюдии, соития и сексуального удовлетворения (оргазма). Наличие негативного психологического фона сопровождается снижением сексуального возбуждения, либидо, а в тяжелых случаях приводит к полному отсутствию полового влечения. Отсутствие адекватного физиологического ответа на интимную близость, предшествующую половому акту (фаза прелюдии), проявляется в виде недостатка или отсутствия секрета желез, расположенных в области преддверия влагалища (бартолиновы железы). Дефицит смазки приводит к тому, что женщине больно заниматься сексом.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К диспареунии, обусловленной психологическими факторами, могут приводить следующие аффективные и психогенные расстройства:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Депрессия;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Тревожные расстройства;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Навязчивые состояния и фобии (страх перед нежелательной беременностью, заражением инфекциями, передающимися половым путём, неспособностью удовлетворить партнёра).</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Дополнительные факторы, способные приводить к психогенной диспареунии:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Негативный сексуальный опыт, вызвавший чувство стыда, вины или снижение самооценки;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Физическое, психическое или сексуальное насилие в детском и подростковом возрасте;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Потеря близких: родителей, супруга, жениха;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Психологические травмы, вызвавшие снижение самооценки (могут быть связаны с бесплодием, преждевременным климаксом, последствиями калечащих травм, перенесенными заболеваниями и оперативными вмешательствами, включая удаление матки, молочных желез);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Проблемы между партнёрами: отсутствие доверия, измены, обиды, ссоры, негативные эмоции.</span></li>\r\n</ul>\r\n<p> </p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К болевым ощущениям приводят различные расстройства. Каждое из них имеет свой механизм формирования и определяет патогенез диспареунии:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При нехватке смазки, атрофических или воспалительных заболеваниях влагалища боль возникает из-за раздражения и травматизации слизистой оболочки.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При вагинизме, пороках развития, стенозе влагалища дискомфорт вызывают анатомические особенности, которые препятствуют половому акту.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При эндометриозе неприятные ощущения связаны с расположением эндометриоидных очагов. Давление и их физическое растяжение при половом акте вызывают боль.</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">При загибе и опущении матки, низко расположенных миоматозных узлах происходит смещение органов, что ведёт к дискомфорту при половой жизни.</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">При воспалительных заболеваниях матки, придатков и мочевого пузыря боль может присутствовать и вне полового акта, а во время него — усиливаться из-за давления на воспалённые ткани.</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">При психосоматической диспареунии стресс и сопутствующие негативные эмоции вызывают спазмы мышц тазового дна. Это сопровождается болью и нарушением микроциркуляции крови в тканях при половом акте. Поначалу такое нарушение временно и обратимо, но в дальнейшем становится постоянным и приводит к структурным изменениям. Таким образом психогенетические и органические расстройства влияют друг на друга.</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">При психогенной диспареунии к боли приводит неразрешённый внутренний конфликт. Дискомфорт возникает из-за невозможности изменить сложившуюся ситуацию и от неудовлетворённости отношениями. Женщина ищет возможность избежать половую близость, а боль служит наиболее психологически и социально приемлемым способом для этого.</span></li>\r\n</ul>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для диагностики диспареунии требуется проведение гинекологического, психологического и сексологического обследования. Иногда консультация психолога и сексолога необходима и постоянному партнеру пациентки.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При беседе с женщиной выясняют различные аспекты, которые могут пролить свет на этиологию возникшей проблемы (время начала болей, их локализация, характер и интенсивность, обстоятельства появления, предшествующие методы лечения). Тщательным образом собирают акушерско-гинекологический анамнез, особое внимание обращают на наличие вагинальных симптомов (патологических белей, жжения, зуда), перенесенные половые инфекции и другие заболевания, родовые травмы, операции на брюшной полости, способы контрацепции.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При обследовании пациентки на кресле гинеколог внимательно осматривает область вульвы, визуально определяя признаки воспаления, атрофии, поражения кожи промежности. Бимануальное исследование позволяет обнаружить болезненность в области преддверия влагалища, матки, придатков. С целью исключения или подтверждения органических причин диспареунии производится забор мазков на флору, половые инфекции, онкоцитологию; выполняется УЗИ органов малого таза. При отсутствии данных за органическую диспареунию женщину направляют к психотерапевту или сексологу для проведения специализированной диагностики.</span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При наличии подтвержденных органических причин диспареунии лечение проводится специалистами соответствующего профиля (гинекологами, урологами, венерологами). С учетом выявленных этиологических факторов назначается лекарственная терапия (противовоспалительные, седативные средства, ЗГТ, местные анестетики), гинекологический массаж, физиотерапия. </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">По показаниям производится хирургическое вмешательство (коррекция анатомических дефектов, вагинопластика, рассечение фиброзированной девственной плевы, удаление кондилом, удаления кисты бартолиниевой железы и пр.). При необходимости подбирается подходящий метод контрацепции. При пролапсе гениталий рекомендуется использование маточного кольца.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В лечении психогенной диспареунии могут использоваться индивидуальная и парная психотерапия, психокоррекция супружеской пары, гипносуггестивная терапия, телесно-ориентированная терапия, аутотренинг, секс-терапия. Целью психотерапевтического лечения является изменение отношения к половому акту, устранение ожидания боли, гармонизация супружеских отношений. Даются рекомендации по изменению сексуальной техники, подбору лубрикантов, использованию приемов для расслабления мышц влагалища. Важно помнить, что эффективное устранение психогенной диспареунии возможно лишь при заинтересованном участии обоих партнеров.</span></p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Для профилактики органической формы диспареунии необходимо своевременное лечение гинекологической патологии.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Сохранению сексуальной функции способствует:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Родительское воспитание с позитивным отношением к сексуальным аспектам жизни.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Гармоничное психосексуальное развитие и личностные особенности.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-style: normal; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Удовлетворённость партнёрскими отношениями.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При психогенной диспареунии важную роль играет партнёр. Его невротические личностные черты (повышенная тревожность, неуверенность в себе, зависимость), особенно в сочетании с нехваткой позитивного сексуального опытом, ухудшают ситуацию.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Боли могут возникать в разное время. Однако признаки возникновения болей можно обнаружить заранее:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Тянущая/резкая/блуждающая боль в паху;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Неопределенные боли в области малого таза;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Частые позывы, рези и зуд при мочеиспускании;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пульсация в половых губах при возбуждении;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Болезненные месячные.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Боли могут быть во время проникновения члена во влагалище:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ощущение сжатости;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Неприятное трение;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Уплотнение во влагалище после проникновения пениса;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Резкие боли с правой и/или левой сторон при глубоком проникновении;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Пульсирующая и/или спазматическая боль внизу живота;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Резь, пронзающая и отдающая в ногу.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Во время секса и после могут возникать следующие симптомы:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Раздражение наружных половых органов, сопровождающееся покраснением;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Цистит;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Выделения, вплоть до гнойных, неприятного цвета и запаха;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Припухлость и отечность в паху.</span></li>\r\n</ul>\r\n<p> </p>",
"image": null,
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},
"code": "K30",
"name": "Расстройство пищеварения",
"icd_name": "Диспепсия",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "k30_rasstroystvo_pischevareniya",
"lead": "расстройство пищеварения, возникающее в результате недостатка ферментов или в результате нерационального питания",
"description": "<p><span id=\"docs-internal-guid-b3f153a7-7fff-101c-8391-328f5edcadcb\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Диспепсия - это расстройства пищеварения и желудочно-кишечном тракте, комплекс симптомов, свойственных многим заболеваниям, а также пограничным состояниям. </span></span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Выделяют несколько форм в зависимости от причин, которые вызывают развитие синдрома:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">простую диспепсию. Она еще называется алиментарной. Вызвана проблемами с питанием. В свою очередь бывает жировой (мыльной), бродильной и гнилостной диспепсией. В последнем случае она развивается, если в еде преобладают белковые продукты или используется несвежее мясо. Бродильная развивается от чрезмерного употребления углеводов (хлеба, капусты, бобовых, сахара) и напитков, вызывающих брожение (пиво и квас). Жировая диспепсия развивается при неумеренном потреблении жирной еды, особенно это касается свинины и баранины;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">диспепсию, связанную с дефицитом выделяемых ферментов для переваривания еды в кишечнике и желудке. В свою очередь она бывает гастрогенной (недостаток ферментов в желудке), панкреатогенной (дефицит веществ поджелудочной железы), энтерогенной (нехватка кишечных соков), гепатогенной (недостаточное выделение желчи из печени);</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">диспепсию, которая связана с проблемами всасывания еды в кишечнике при синдроме мальабсорбции. В результате этого питательные компоненты не поступают из кишечника в кровь;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">диспепсия, которая связана с кишечными инфекциями. В данном случае это может быть как дизентерия, так и сальмонеллез.</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">интоксикационную. Она проявляется из-за отравления при разных болезнях, в том числе гриппе, хирургических патологиях в острой форме, а также при употреблении ядов.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Все эти факторы могут способствовать возникновению болезни. Симптомы и лечение диспепсии желудка и кишечника напрямую зависят именно от причин.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-family: Verdana; font-size: xx-small;\"><span style=\"white-space: pre-wrap;\"> </span></span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span><span style=\"font-family: Verdana; font-size: xx-small;\"><span style=\"white-space: pre-wrap;\">К факторам риска относятся:</span></span></span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">частые и сильные стрессы, эмоциональное напряжение. В этом случае патология будет иметь невротический генезис;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">некоторое употребление медикаментов. Это касается антибиотиков, гормональных или противоопухолевых и других средств;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">неправильное питание. Чаще всего это касается переедания;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">интоксикация. В данном случае может быть как заболевание вирусного или бактериального происхождения, так и бытовое отравление;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">чрезмерное выделение соляной кислоты;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">проблемы с моторикой желудочно-кишечного тракта.</span></li>\r\n</ul>",
"pathogenesis": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">В результате воздействия различных факторов на стенку желудка повышается чувствительность висцеральных рецепторов, возникает дискоординация моторики желудка и тонкого кишечника, нарушается нормальная секреция пищеварительных соков. Проявлениями данных расстройств служат гастропарез (сопровождается тяжестью в эпигастрии, тошнотой и рвотой), повышенная висцеральная восприимчивость к растяжению (ощущение переполненности желудка, голодные боли в подложечной области), неполное расслабление мышечного слоя органа (чувство раннего насыщения), замедление продвижения пищевых масс из желудка в кишечник.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Прежде чем начать лечение диспепсии, необходимо пройти обследование, которое включает не только описание жалоб, внешний осмотр, но и следующее:</span></p>\r\n<p> </p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #465a63; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">лабораторные исследования – общий и биохимический анализ крови, изучение кала на наличие крови, копрограмму;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 8pt; font-family: Verdana; color: #465a63; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">инструментальные исследования – тест на выделения кислоты желудком, эзофагогастродуоденоскопию, исследование желудочных материалов на наличие хеликобактер пилори, УЗИ органов брюшной полости, колоноскопию, рентгенографию, компьютерную томографию, эзофагеальную и антродуоденальную манометрию.</span></p>\r\n</li>\r\n</ul>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Лекарственная терапия включает в себя ферментные препараты.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">В качестве симптоматического лечения диспепсии можно применять следующие препараты: альмагель, маалокс и другие средства, снижающие кислотность; препараты, которые снижают желудочную секрецию — омепразол, ранитидин, фамотидин и др.; ферментные препараты — ацидинпепсин, абомин, панкреатин и др.; прокинетики — мотилиум и др.; препараты для восстановления микрофлоры — бификол, колибактерин и ряд других групп.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Очень большую роль в лечении диспепсии играет нормализация питания.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Обычно назначается голодание в течение 1–1,5 суток, затем:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">при гнилостной диспепсии в суточном рационе необходимо увеличение количество углеводов</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">при бродильной диспепсии — белков (одновременно уменьшают количество низкомолекулярных углеводов)</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">при жировой диспепсии ограничивают поступление в организм жиров, особенно тугоплавких, животного происхождения</span></li>\r\n</ul>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Необходимо перейти на рациональное питание, отказаться от вредных и несвежих продуктов, курения. Обязательно соблюдать нормы гигиены, вести здоровый образ жизни. Допускаются умеренные физические нагрузки. Регулярно необходимо проходить плановые осмотры у врача, своевременно лечить любые болезни.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Синдром диспепсии представляет собой расстройства пищеварения и симптомы, которые свойственные различным заболеваниям желудочно-кишечного тракта и их пограничным фазам.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Когда нарушается пищеварение, то появляются симптомы, которые объединены общим названием – диспепсия желудка, сюда относится:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">проблемы с глотанием;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">тошнота и рвотные приступы;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отрыжка;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">боли в области желудка;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">изжога;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">урчание в животе;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">вздутие живота;</span></li>\r\n<li><span style=\"font-size: 7pt; color: #000000; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">запор, диарея.</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Диспепсия желудка и кишечника вызывает боли в эпигастральной области. Они могут быть как достаточно интенсивными, так и в виде легкого дискомфорта. Возникает чувство быстрого насыщения и переполненности, а вследствие этого еще и тошнота, отрыжка, изжога. Еще один тревожный признак – утрата аппетита, причем быстро и резко. После этого у человека начинается беспричинно снижаться вес. Кишечная диспепсия сопровождается урчанием в животе, метеоризмом, поносом или запором.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Нарушение процесса переваривания еды в кишечнике может указывать на такие патологии как дисбактериоз, дивертикулит, энзимопатия, энтерит, колит, опухоли в кишечнике, синдром раздраженного кишечника, заболевания поджелудочной железы, патологии метаболизма. Также диспепсия кишечника может свидетельствовать о том, что в нем развивается инфекция (дизентерия, холера, туберкулез кишечника, сальмонеллез и пр.).</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Выделяют 2 основные группы диспепсических расстройств – функциональную диспепсию и органическую. В первом случае обнаруживаются только нарушения деятельности органа, то есть функциональные поражения, а во втором они носят исключительно органический характер. В последнем случае симптоматика будет более выраженной, при этом расстройства продолжаются долгое время.</span></p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
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},
"code": "N90.3",
"name": "Дисплазия вульвы неуточненная",
"icd_name": "Дисплазия вульвы неуточненная",
"gender": 2,
"age_min": 40,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 1,
"slug": "n90.3_displaziya_vulvy_neutochnennaya",
"lead": "болезнь наружных половых органов женщины, проявляющаяся аномальными изменениями в строении эпителия гениталий",
"description": "",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хроническая прогрессирующая инфекция ВПЧ является одной из основных причин развития дисплазии вульвы. Помимо вируса папилломы человека дисплазия может быть обусловлена следующими факторами:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">ЗППП</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">воспалительные болезни влагалища и наружных половых органов, носящие хронический характер</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">низкий иммунный статус</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">сбои в обмене веществ</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">дисфункция эндокринной системы</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">раннее вступление в половую жизнь</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">табакокурение</span></li>\r\n</ul>\r\n<p> </p>",
"pathogenesis": "",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Чтобы диагностировать появление дисплазии вульвы у пациентки и определить ее онкогенность, врачу акушеру-гинекологу нужно провести целый ряд медицинских мероприятий:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Осмотр на кресле. Первое, что сделает доктор — проведет осмотр наружных и внутренних органов пациентки. Множественные очаги поражения, язвочки, белые бляшки насторожат врача.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Кольпоскопия. Позволит провести более детальный осмотр под многократным увеличением.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Шиллер-тест. Этот метод укажет врачу, есть ли изменения эпителия в половых органах женщины. Если ткани женщины равномерно окрашиваются йодом – они здоровы. Если же врач замечает неравномерность окраса, это позволяет заподозрить развитие неблагоприятных процессов в организме пациентки.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Анализы. Первый, и самый главный в этом случае анализ, который назначит доктор – анализ на вирус папилломы человека. Этот анализ позволит не только установить, есть ли в организме пациентки ВПЧ, но и также определить его тип, если этот вирус имеется. Этот анализ играет важную роль в скрининге дисплазии вульвы, потому что именно вирус папилломы человека, по многочисленным данным, провоцирует развитие дисплазии вульвы.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Онкоцитология (цитологическое исследование). Этот анализ позволит ответить на вопрос – есть ли атипичные клетки в половых органах женщины, развивается ли у нее онкопроцесс.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Биопсия. Биопсия позволит отправить атипичные клетки на анализ и подтвердить или опровергнуть подозрение на злокачественные образования.</span></li>\r\n</ul>\r\n<p> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Терапия атипической гиперплазии вульвы основана на следующих подходах:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Консервативная терапия. Базируется на использовании гормональных средств, общеукрепляющих, седативных и других препаратов, а также следовании предписанному рациону. Целью консервативной терапии является уменьшение локальных проявлений заболевания, ремиссия и улучшение психологического статуса. При в положительном тесте на ВПЧ необходим прием иммуностимулирующих и противовирусных препаратов.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хирургическая операция. Требуется в случае тяжелых форм заболевания, выраженной онкоугрозе, рецидивировании болезни и обширном поражении эпителия. Проводится поверхностная вульвэктомия, направленная на удаление наружного эпидермиса с последующей пластической реконструкцией гениталий.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Методы, альтернативные хирургической операции. Для замены оперативного вмешательства может применяться воздействие с помощью лазера, жидкого азота и радиоволн. Однако эти методики эффективны лишь на ранних стадиях болезни и нацелены на пациенток, не достигших климактерического возраста.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Фотодинамическая терапия. Метод основан на воздействии особого светового излучения на патологические клетки, которое приводит их гибели.</span></li>\r\n</ul>\r\n<p> </p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Специфические меры профилактики не разработаны. Женщинам необходимо правильно питаться, избегать беспорядочных половых связей, отказаться от пагубных привычек, применять барьерную контрацепцию во время полового акта, санировать очаги хронических инфекций и регулярно посещать врача-гинеколога.</span></p>",
"clinical_picture": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Часто атипическая гиперплазия вульвы протекает скрытно, что создает большие сложности с ее своевременным выявлением. Обнаружение заболевания почти всегда происходит при плановом осмотре или в ходе обращения к гинекологу по какой-либо проблеме. Однако иногда незначительные проявления </span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">дисплазии может заметить и не специалист. К таковым относится появление кондилом на анусе и наружных половых органах.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При прогрессировании атипической гиперплазии вульвы в районе гениталий возникает непрекращающийся зуд, распространяющийся на влагалище и анус. К сожалению, эти проявления не являются специфическими для данного заболевания и могут отмечаться при других гинекологических патологиях. Например, они присутствуют при кольпите и вагините.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К другим симптомам дисплазии вульвы относятся:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">отечность гениталий</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">гнойные и слизистые выделения из влагалища</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">белые бляшки на гениталиях</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">язвочки и сухость слизистых оболочек наружных половых органов</span></li>\r\n</ul>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При переходе заболевания на более поздние стадии степень и масштаб поражения слизистых гениталий возрастают. Из-за смазанности клинической картины диагностика атипической гиперплазии на начальных этапах представляется затруднительной, что повышает риски, сопряженные с этим заболеванием.</span></p>",
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"code": "N87",
"name": "Дисплазия шейки матки",
"icd_name": "Дисплазия шейки матки",
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"lead": "Нарушение здоровья, относящееся к группе невоспалительные болезни женских половых органов",
"description": "Дисплазия шейки матки (цервикальная дисплазия) – это состояние покрывающего шейку матки эпителия, которое характеризуется изменением числа слоев и строения образующих его клеток. При этом в процесс не вовлекается базальная мембрана и самые верхние клеточные слои. Дисплазия относится к заболеваниям, которые при стечении обстоятельств могут стать причиной развития злокачественной опухоли шейки матки.",
"etiology": "<p>Основной причиной считают инфицирование вирусом папилломы человека (ВПЧ). Заражение ВПЧ происходит только половым путем. Риск инфицирования повышен в следующих случаях:</p>\r\n<ul>\r\n<li>иммунодефицит – подавление иммунной реактивности хроническими заболеваниями, стрессами, лекарственными препаратами, неправильным питанием и т. д.;</li>\r\n<li>табакокурение активное и пассивное – увеличивает вероятность развития дисплазии шейки матки в 4 раза;</li>\r\n<li>затяжные хронические воспаления половых органов;</li>\r\n<li>нарушения гормонального фона, вызванные менопаузой, беременностью, употреблением гормоносодержащих лекарств;</li>\r\n<li>ранняя половая жизнь и роды;</li>\r\n<li>травматические повреждения шейки матки.</li>\r\n</ul>",
"pathogenesis": "<p>При формировании патологического процесса происходит нарушение слоев эпителия, поверхностные и переходные эпителиоциты содержат делящиеся (митотически активные) клетки, которых в норме быть не должно. Это приводит к гиперплазии (увеличение количества эпителиоцитов) слизистой. Механизмом формирования дисплазии шейки матки является нарушение регуляции митоза клеток, вследствие которого происходит их деление в тех слоях слизистой, в которых этого не должно быть.</p>",
"diagnostics": "<p>Диагностика дисплазии шейки матки включает:</p>\r\n<ul>\r\n<li>осмотршейки матки при помощи влагалищных зеркал – с целью обнаружения видимых глазом, клинически выраженных форм дисплазии (изменение окраски слизистой, блеск вокруг наружного зева, пятна, разрастание эпителия и др.);</li>\r\n<li>кольпоскопия – осмотр шейки матки специальным оптическим аппаратом, увеличивающим изображение более чем в 10 раз и одновременное проведение диагностических проб - обработки шейки матки раствором Люголя и уксусной кислоты;</li>\r\n<li>ПАП-мазок ф– при дисплазии шейки матки исследование под микроскопом соскоба, полученного с разных участков, позволяет выявить атипичные клетки. Также с помощью ПАП-мазка обнаруживаются клетки-маркеры папилломавирусной инфекции, имеющие сморщенные ядра и ободок, являющиеся местом локализации вируса папилломы человека;</li>\r\n<li>гистологического исследованиябиоптата – фрагмента ткани, взятого в ходе биопсии шейки матки из зоны, подозрительной на дисплазию. Является наиболее информативным методом выявления дисплазии шейки матки;</li>\r\n</ul>\r\n<p>иммунологических ПЦР-методов – для выявления ВПЧ-инфекции, установления штаммов вируса и вирусной нагрузки (концентрации вируса папилломы в организме). Выявление наличия или отсутствия онкогенных типов ВПЧ позволяет определить выбор метода лечения и тактику ведения пациентки с дисплазией шейки матки.</p>",
"treatment": "<p>Медикаментозное лечение включает в себя препараты для повышения иммунитета в виде иммуномодуляторов, а также средств интерферона. Применяют их при обширных поражениях и рецидивирующей форме дисплазии.</p>\r\n<p>К хирургическому лечению прибегают в случае двукратного положительного результата анализа на дисплазию. Перед любой оперативной методикой назначаются противовоспалительные препараты для санации очага. Очень часто после предоперационного лечения степень поражения дисплазией уменьшается в размерах или полностью исчезает. Операции всегда выполняют в первую фазу месячного цикла, а именно на 6-10 день, при условии отсутствия воспалительного процесса во влагалище и матке, а также беременности.</p>\r\n<p>Современные хирургические методики лечения дисплазии шейки матки следующие:</p>\r\n<ul>\r\n<li>Лазерная хирургия(лазерная вапоризация, лазерная конизация, лазерное прижигание). Это способ воздействия на патологические ткани посредством пучка лазера с низкой интенсивностью. Благодаря этому участки дисплазии нагреваются и разрушаются, на их месте образуется некроз.</li>\r\n<li>Холодовая деструкция(криодеструкции, криоконизация).</li>\r\n<li>Электрическая эксцизия(диатермокоагуляция, процедура петлевой электрической эксцизии).</li>\r\n<li>Конизация шейки матки. При ней специальным ножом в виде петли удаляют участок шейки конусовидной формы.</li>\r\n<li>Криотерапия.Данная технология предусматривает ликвидацию очага на шейке жидким азотом.</li>\r\n<li>Радиоволновая хирургия.</li>\r\n<li>Ампутация шейки матки. Радикальное удаление шейки при невозможности проведения или неэффективности других методов.</li>\r\n</ul>\r\n<p> </p>",
"prevention": "<p>Для профилактики дисплазии шейки матки и ее рецидивов рекомендуется:</p>\r\n<ul>\r\n<li>включение в рацион питания всех микроэлементов и витаминов, в особенности витаминов А, группы В, селена;</li>\r\n<li>своевременная санация всех очагов инфекций;</li>\r\n<li>отказ от табакокурения;</li>\r\n<li>применение барьерной контрацепции (при случайных половых контактах);</li>\r\n<li>регулярное наблюдение гинеколога(1-2 раза в год) с исследованием цитологического соскоба с шейки матки</li>\r\n</ul>\r\n<p> </p>",
"clinical_picture": "<p>Типичная клиническая картина провялятся в большинстве случаев уже в тяжелой степени дисплазии шейки матки и присоединении вторичной инфекции с развитием воспаления (цервицит, кольпит). </p>\r\n<p>Пациентка с дисплазией шейки матки может предъявлять следующие жалобы:</p>\r\n<ul>\r\n<li>бели (выделения) – обильные, с неприятным запахом;</li>\r\n<li>кровянистые выделения (часто контактные, то есть после полового акта, гинекологического осмотра);</li>\r\n<li>зуд;</li>\r\n<li>чувство жжения;</li>\r\n<li>боль, возникающая во время секса.</li>\r\n</ul>\r\n<p> </p>",
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