ВОзвращает список болезней. Можно фильтр/искать

search, age, gender, parent, symptoms, sort_name, sort_by, rand, branches
GET /disease/?format=api&ordering=icd_name&page=459
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/json
Vary: Accept

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            },
            "code": "C33",
            "name": "Рак трахеи",
            "icd_name": "Рак трахеи",
            "gender": 0,
            "age_min": 40,
            "age_max": 70,
            "cause": [
                "0"
            ],
            "periodicity": 1,
            "slug": "c33_rak_trahei",
            "lead": "онкологическое заболевание дыхательных путей, характеризующееся наличием новообразования, которое произрастает из тканей стенки трахеи",
            "description": "",
            "etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Одна из основных причин возникновения рака трахеи &ndash; отягощенная наследственность. Риск развития злокачественного новообразования значительно увеличивается, если подобный диагноз был поставлен близким родственникам.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">К другим причинам относятся:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Активное и пассивное курение.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Вирусная инфекция. Главный инфекционный агент &ndash; вирус папилломы человека.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Применение лучевой терапии в борьбе с онкологией смежных с трахеей органов.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Выделяют 4 стадии первичной онкопатологии трахеи. Учитывается степень распространенности опухолевого процесса, вовлеченность лимфатических узлов, наличие отдаленных от опухоли метастатических очагов.</span></p>",
            "pathogenesis": "",
            "diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При обращении в клинику пациент направляется на комплексное обследование, которое включает:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лабораторные исследования. Диагностика включает биохимическое и развернутое клиническое исследование крови, определение онкомаркеров РЭА, коагулограмму и общий анализ мочи. При проведении исследования крови могут быть определены характерные специфические изменения.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Физикальное обследование. Врач оценивает функциональный статус для определения сопутствующих патологий и вторичных признаков заболевания, оказывающих влияние на выбор лечебной тактики.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инструментальные методы. Проводится трахео-бронхоскопию, при которой делают биопсия. Данный метод является наиболее информативным, т. к. позволяет не только визуализировать опухоль, но и определить ее размеры, а также область локализации. Бронхоскопия оценивает угрозу осложнений и позволяет получить материал для проведения морфологического исследования.</span></li>\r\n</ul>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Среди дополнительных диагностических мер следует выделить УЗИ шейной и надключичной зоны, рентген грудины, компьютерной томографии органов грудной клетки и ЭКГ.</span></p>",
            "treatment": "<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Основным методом лечения рака трахеи является хирургическое удаление опухоли. Хирург удаляет пораженный участок трахеи с захватом небольших участков выше и ниже, затем соединяет оставшиеся концы. Такие операции очень сложны из-за особенностей кровоснабжения трахеи. Если сильно повредить кровеносные сосуды, то заживление будет происходить дольше и хуже.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Некоторым пациентам, которым противопоказано хирургическое лечение, могут быть выполнены эндоскопические вмешательства. Они помогают уменьшить злокачественную опухоль и впоследствии упросить ее удаление:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лазерная хирургия предполагает уничтожение опухолевой ткани с помощью луча лазера высокой интенсивности.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Криохирургия. Во время процедуры на злокачественное новообразование наносят жидкий азот в виде спрея, и низкая температура уничтожает раковые клетки.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Брахитерапия является разновидностью лучевой терапии. Источник излучения находится на конце бронхоскопа, его направляют непосредственно на злокачественную опухоль. Раковые клетки получают максимальную дозу облучения, при этом практически не затрагиваются здоровые ткани.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Фотодинамическая терапия. На поверхность опухоли наносят специальное вещество &mdash; фотосенсибилизатор, а затем воздействуют на нее светом определенной длины волны. Под действием света фотосенсибилизатор активируется и разрушает опухолевые клетки.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Если неоперабельная опухоль блокирует просвет трахеи, можно выполнить паллиативные хирургические вмешательства. Во время стентирования в заблокированный участок устанавливают короткую трубку с сетчатой стенкой из металла &mdash; стент. Это эндоскопическая процедура. Также можно выполнить трахеостомию &mdash; сформировать отверстие, которое будет сообщать просвет трахеи с передней поверхностью шеи ниже места сужения. Через эту трахеостому пациент сможет дышать.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лучевая терапия</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лучевую терапию зачастую назначают после удаления рака трахеи, чтобы уничтожить опухолевые клетки, которые могли остаться в организме пациента. </span></p>",
            "prevention": "<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Отказ от курения и алкоголя</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Своевременное лечение хронических заболеваний</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Соблюдение правил работы с токсичными веществами</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ежегодное прохождение профилактических осмотров</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>\r\n<p>&nbsp;</p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\">&nbsp;</p>",
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            "code": "C53",
            "name": "Рак шейки матки",
            "icd_name": "Рак шейки матки",
            "gender": 2,
            "age_min": 20,
            "age_max": 85,
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            "slug": "c53_rak_sheyki_matki",
            "lead": "Злокачественное новообразование шейки матки- онкологическое заболевание.",
            "description": "Злокачественное новообразование шейки матки- онкологическое заболевание. В структуре онкологической заболеваемости женщин злокачественные опухоли шейки матки составляют почти 15% и среди поражений органов репродуктивной системы стабильно занимают третье место после рака молочной железы и рака эндометрия.",
            "etiology": "<p>Ведущую роль в канцерогенезе рака шейки матки отводят вирусу папилломы человека как наиболее частому виду инфекций, передающихся половым путем Возбудитель вируса папилломы человека — группа ДНКсодержащих вирусов, относящихся к семейству Papavaviriade (HPV — human papilloma virus), обладающих способностью инфицировать и трансформировать эпителиальные клетки шейки матки.</p>",
            "pathogenesis": "",
            "diagnostics": "<p>При выяснении анамнеза необходимо обратить внимание на перенесённые заболевания, нарушения менструальной и репродуктивной функций, изменения в работе кишечника и мочевого пузыря, возраст больной, семейное положение, образ жизни.</p>\r\n<p>Шейка матки доступна для визуальных и инвазивных методов исследования, что способствует выявлению РШМ на ранних стадиях. Ранняя диагностика включает несколько различных исследований.</p>\r\n<p>Расширенная кольпоскопия позволяет изучать состояния эпителия шейки матки под 7,5–40кратным увеличением. Особое внимание уделяют зоне трансформации. Для повышения информативности исследования используют ряд специфических проб. Одна из них состоит в аппликации на шейку матки 3–5% раствора уксусной кислоты, что позволяет оценить состояние терминальной сосудистой сети, питающей эпителий шейки матки.</p>\r\n<p>В качестве опухолевого маркёра плоскоклеточного рака шейки матки в сыворотке крови пациентки определяют уровень специфического Аг — SCC. В норме он не превышает 1,5 нг/мл.</p>\r\n<p>При подозрении на предопухолевую патологию или рака шейки матки необходимо проводить углублённую диагностику (биопсия шейки матки, выскабливание цервикального канала).</p>\r\n<p>Гистологическое исследование считают заключительным и решающим методом диагностики РШМ, позволяющим определить характер морфологических и структурных изменений.</p>\r\n<p>Стадию РШМ определяют с помощью УЗИ, рентгенографии лёгких, цистоскопии, ирригоскопии. По показаниям выполняют КТ и МРТ.</p>",
            "treatment": "<p>При раке шейки матки IА1 стадии (без неблагоприятных факторов прогноза) у лиц молодого, репродуктивного возраста, соматически отягощённых больных может быть выполнена высокая конусовидная ампутация шейки матки. После этой операции (в пределах здоровых тканей) показано строгое динамическое наблюдение.</p>\r\n<p>Для сохранения репродуктивной функции можно выполнить высокую конусовидную ампутацию шейки матки с забрюшинной или лапароскопической тазовой лимфодиссекцией.</p>\r\n<p>Стандартное хирургическое лечение РШМ IB1 стадии: расширенная экстирпация матки с придатками.</p>\r\n<p>У больных репродуктивного возраста яичники могут быть сохранены и выведены за пределы таза (возможно проведение послеоперационной лучевой терапии). Транспозиция яичников может быть выполнена при плоскоклеточном раке высокой и умеренной степени дифференцировки и отсутствии опухолевой сосудистой эмболии.</p>\r\n<p>Выбор метода лечения зависит от возраста, соматического статуса, мнения больной. Тактику лечения определяют на консилиуме.</p>",
            "prevention": "<p>Риск заболеть раком шейки матки наиболее высок у женщин группы риска (раннее начало половой жизни, частая смена сексуальных партнеров, наличие инфекций, передающихся половым путем, первые роды в очень раннем возрасте, частые аборты). Основным способом профилактики рака шейки матки считают своевременное выявление фоновых, особенно предраковых, процессов и их лечение. Не менее важно использование барьерных средств контрацепции, препятствующих распространению инфекций, передающихся половым путем к которым относят и вирус папилломы человека, считаемый этиологическим фактором развития вируса папилломы человека. </p>",
            "clinical_picture": "<p>Рак шейки матки принадлежит к опухолям, которые длительное время протекают бессимптомно. Появление клинических симптомов и жалоб говорит о далеко зашедшем опухолевом процессе. Наиболее часто больные предъявляют жалобы на обильные , кровянистые выделения и боли.</p>\r\n<p>Первые симптомы рака шейки матки.  носят жидкий, водянистый характер и обусловлены лимфореей из участка опухоли, подвергшегося некрозу или распаду.</p>\r\n<p>Кровотечения — самый частый клинический симптом. Кровотечения при раке шейки матки носят характер многократно беспорядочно повторяющихся кровянистых выделений, усиливающихся в предменструальном и постменструальном периодах. В начале заболевания кровянистые выделения часто носят характер контактных, возникают после полового акта, натуживания или пальцевого исследования шейки матки.</p>\r\n<p>Боли по своему характеру, локализации, интенсивности бывают различны, бывают локализованы в поясничной области, крестце и под лоном.</p>\r\n<p>Поздние симптомы рака шейки матки. Развиваются в результате регионарного метастазирования, прорастания соседних органов, присоединения воспалительного компонента. К ним относят боли,  тела, появление отёков конечностей, нарушения работы кишечника, мочевыделительной системы.</p>\r\n<p>Общие симптомы рака шейки матки. К ним относят общую , повышенную \"></a>, .</p>",
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