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"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Миокардиты включают большую группу заболеваний сердечной мышцы воспалительного генеза, проявляющихся поражением и нарушением функции миокарда. Частой причиной миокардита являются различные инфекционные заболевания:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">вирусные (вирусы Коксаки, гриппа, аденовирусы, герпеса, гепатита В и С);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">бактериальные (коринеобактерии дифтерии, стафилококки, стрептококки, сальмонеллы, хламидии, риккетсии);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">грибковые (аспергиллы, кандиды),;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">паразитарные (трихинеллы, эхинококки) и др.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Тяжелая форма миокардита может возникать при дифтерии, скарлатине, сепсисе. Высокой кардиотропностью обладают вирусы, вызывающие миокардит в 50% случаев. Иногда миокардит развивается при системных заболеваниях соединительной ткани: системной красной волчанке, ревматизме, васкулитах, ревматоидном артрите, при аллергических заболеваниях. Также причиной миокардита может служить токсическое воздействие некоторых лекарственных препаратов, алкоголя, ионизирующее излучение. Тяжелое прогрессирующее течение отличает идиопатический миокардит невыясненной этиологии.</span></p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Провоцирующими моментами возникновения миокардита являются острые инфекции (чаще вирусные), очаги хронической инфекции; аллергозы, нарушенные иммунологические реакции; токсическое воздействие на организм (лекарств, алкоголя, наркотиков, ионизирующего излучения, при тиреотоксикозе, уремии и др.).</span></p>\r\n<p> </p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Наиболее важную патогенетическую роль играет М-протеин, который обладает сильной иммуногенностью, т. е. способностью вызывать иммунный ответ. Этот белок входит в состав мембраны стрептококка и имеет ту же молекулярную структуру, что и мембраны кардиомиоцитов (феномен молекулярной мимикрии). Благодаря такому феномену возникает перекрестная аутоиммунная реакция, при которой Т-лимфоциты наряду с бактериями атакуют собственные клетки сердца. В патогенезе также принимают участие экзоферменты стрептококка, которые обладают прямым повреждающим действием на клетки соединительной ткани (стрептолизин О, стрептолизин S, гиалуронидаза, стрептокиназа).</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Патоморфологически ревмокардит протекает в 4 стадии, каждая из которых продолжается 1-2 месяца: мукоидное набухание, фибриноидное набухание, образование ревматической гранулемы, склероз. В процессе этих стадий происходит разрушение основного вещества соединительной ткани, образуются очаги некроза и ревматические гранулемы. Исходом является склероз, т. е. рубцевание. Наиболее пагубное влияние эти процессы оказывают на сердечные клапаны, которые деформируются, что приводит к формированию сердечных пороков. Именно пороки сердца в исходе ревматического воспаления и являются чрезвычайно актуальной проблемой.</span></p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Ревмокардит является основным проявлением ОРЛ, для диагностирования которой используются специально разработанные клинические и лабораторные критерии. Они включают кардит, артрит, малую хорею, кольцевидную эритему, подкожные узелки, лихорадку и данные, свидетельствующие о наличии стрептококковой инфекции в организме. Диагностика непосредственно ревмокардита проводится следующими методами:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Аускультативными. При ревмокардите аускультативная картина разнообразна. У пациентов выслушиваются шумы в проекции митрального и аортального клапанов (наиболее специфичны протодиастолический шум и мезосистолический шум Кера-Кумбса), ослабление и глухость тонов сердца, дополнительные тоны, трение перикарда, изменение частоты сердечных сокращений, неритмичное сердцебиение, ритм галопа.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Лабораторными. В общем и биохимическом анализе крови выявляется наличие воспалительных маркеров (нейтрофильный лейкоцитоз, сдвиг лейкоцитарной формулы влево, увеличение скорости оседания эритроцитов, С-реактивного белка). Также обнаруживаются высокие титры антител к стрептококку - антистретолизин-О (АСЛО), антистрептогиалуронидаза (АСГ), антистрептокиназа (АСК), антидезоксирибонуклеаза-В (АДНК-В).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Инструментальными. На ЭКГ обнаруживаются нарушения ритма и проводимости сердца – тахи- или брадикардия, удлинение интервала PQ, экстрасистолия, предсердно-желудочковая блокада I или II степени, признаки перегрузки левых отделов сердца. Эхо-КГ – наиболее точный визуализирующий метод. Выявляет утолщение или деформацию створок клапанов, признаки регургитации (обратного тока крови), снижение сократительной функции сердца (фракции выброса), расширение полостей сердца, утолщение листков перикарда, выпот в перикардиальную полость.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Первым условием успешного лечения является госпитализация в кардиологический стационар или отделение ревматологии. Необходимо соблюдать постельный режим минимум 4 недели. При тяжелом ревмокардите обязателен строгий постельный режим до исчезновения симптомов недостаточности кровообращения. Рекомендуется питание с повышенным содержанием белка и витаминов. Лечение ревмокардита следующее:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Этиотропная терапия. Так как основной причиной ревмокардита является стрептококковая инфекция, этиотропная терапия направлена на ее эрадикацию. Для этого применяются антибиотики пенициллинового ряда – бензилпенициллин, феноксиметилпенициллин. При развитии аллергических реакций на пенициллины их заменяют другими группами антибиотиков – макролидами (азитромицин), цефалоспоринами (цефуроксим), линкозамидами (линкомицин).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Патогенетическая терапия. Подразумевает лечение непосредственного ревматического воспаления. Обычно применяются нестероидные противовоспалительные средства (в основном, это диклофенак). Однако при тяжелом течении ревмокардита необходимы препараты, обладающие мощным противовоспалительным действием. В таких случаях используют глюкокортикостероиды (преднизолон).</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Симптоматическая терапия. Заключается в коррекции сердечной недостаточности. Обязательно нужно ограничить употребление поваренной соли (менее 3 грамм в сутки). Лекарственные средства применяют у пациентов с уже имеющимся пороком сердца и тяжелой недостаточностью кровообращения. Это ингибиторы АПФ, диуретики, бета-блокаторы, сердечные гликозиды, антагонисты альдостерона.</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Хирургическое лечение. Показано при сформировавшихся тяжелых пороках сердца, вызывающих грубые гемодинамические нарушения и резистентных к лекарственной терапии. В зависимости от вида порока (стеноз или недостаточность), а также от пораженного клапана применяются коммисуротомия, вальвулопластика или протезирование клапана искусственными или биологическими протезами.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">При выписке из стационара необходимо постоянное диспансерное наблюдение у кардиолога или ревматолога, периодическое проведение эхокардиографии для оценки состояния клапанов сердца. Обязательно посещение оториноларинголога, который проводит промывание лакун миндалин. При неэффективности промывания прибегают к радикальному методу ‒ тонзиллэктомии. Ее следует выполнять при стихании активного ревматического процесса и стабильном состоянии пациента.</span></p>",
"prevention": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Первичная профилактика подразумевает правильное и своевременное лечение тонзиллита. С этой целью применяются те же антибиотики, что и для лечения ревмокардита. Для предупреждения рецидива ревмокардита существует так называемая вторичная профилактика. Она заключается в ежемесячном внутримышечном введении антибиотиков пенициллинового ряда пролонгированного действия (бензатина бензилпенициллин). Продолжительность такой профилактики зависит от того, сформировался после ревмокардита порок сердца или нет.</span></p>",
"clinical_picture": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Клинические проявления начинают развиваться через 2-3 недели после стрептококковой инфекции верхних дыхательных путей. В начале заболевания симптоматика неспецифична – утомляемость, повышение температуры тела до субфебрильных или фебрильных цифр, потливость. Примерно через неделю присоединяются симптомы со стороны сердца - затруднение дыхания, ощущение сильного сердцебиения и перебоев в работе сердца, боли в области сердца неопределенного характера. В случае тяжелого течения ревмокардита наряду с вышеперечисленными симптомами возникают выраженная одышка, кашель, отеки ног, тяжесть в правом подреберье из-за увеличенной печени. Период атаки ревмокардита продолжается от 2-х до 6-ти месяцев, после чего либо наступает выздоровление, либо формируется порок сердца.</span></p>",
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"name": "Другие ревматические болезни сердца",
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"lead": "Нарушение здоровья, относящееся к группе хронические ревматические болезни сердца",
"description": "Ревмокардит — это основное клиническое проявление ревматизма, относящегося к системным заболеваниям соединительной ткани, при котором патологический процесс локализуется преимущественно в сердце. Ревматизм поражает чаще детей в возрасте 7—15 лет, реже встречается в дошкольном возрасте. ",
"etiology": "<p>Ревматической атаке обычно предшествует стрептококковая инфекция, вызываемая β-гемолитическим стрептококком группы А: скарлатина, тонзиллит, родильная горячка, острый отит, фарингит, рожа. У 97% пациентов, перенесших стрептококковую инфекцию, формируется стойкий иммунный ответ. У остальных лиц стойкого иммунитета не вырабатывается, и при повторном инфицировании β-гемолитическим стрептококком развивается сложная аутоиммунная воспалительная реакция. </p>\r\n<p>Развитию ревматизма способствуют сниженный иммунитет, молодой возраст, большие коллективы (школы, интернаты, общежития), неудовлетворительные социальные условия (питание, жилье), переохлаждение, отягощенный семейный анамнез.</p>",
"pathogenesis": "<p> В патогенезе ОРЛ также можно говорить о ревматической патогенетической триаде: </p>\r\n<ol>\r\n<li>Прямое повреждение миокарда факторами патогенности стрептококка </li>\r\n<li>Аутоиммунный механизм - повреждение миокарда циркулирующими иммунными комплексами (антиген-антитело). </li>\r\n<li>Сосудистый механизм (поражение сосудов миокарда по вышеописанным механизмам ведет к нарушению циркуляции в миокарде — ишемии, ацидозу, — способствуя развитию воспаления, с одной стороны, и реактивному фиброзу, с другой). </li>\r\n</ol>",
"diagnostics": "<p>Клинико-диагностические критерии ОРЛ Киселя-Джонса: </p>\r\n<p>Большие: </p>\r\n<ul>\r\n<li>ревмокардит (преимущественно поражения миокарда в виде миокардита и эндокардит с пороками сердца и без); </li>\r\n<li>полиартрит (преимущественно крупных суставов, мигрирующий характер, без остаточных деформаций, рентгенологически негативный); </li>\r\n<li>малая хорея; </li>\r\n<li>ревматические узелки (подкожные узловатые уплотнения); </li>\r\n<li>анулярная эритема (кольцевидные покраснения кожи туловища и проксимальных отделов конечностей). </li>\r\n</ul>\r\n<p>Малые: </p>\r\n<ul>\r\n<li>клинические: лихорадка, боли в суставах; </li>\r\n<li>лабораторно-инструментальные: </li>\r\n</ul>\r\n<p>а) лабораторные (С-реактивный белок, антистрептолизин-О, ревматоидный фактор); </p>\r\n<p>б) инструментальные (ЭКГ, электромиография, УЗИ сердца). </p>",
"treatment": "<p> Активная фаза ревматизма требует госпитализации пациента и соблюдения постельного режима. Лечение проводится ревматологом и кардиологом. Применяются гипосенсибилизирующие и противовоспалительные препараты, кортикостероидные гормоны, нестероидные противовоспалительные препараты, иммунодепрессанты.</p>",
"prevention": "<p>Первичная: своевременная санация стрептококковых инфекций (ангины, стрептодермии, лечение болезней полости рта, болезней ЛОР-органов, правильная гигиена и т. д.), закаливание и т. д. </p>\r\n<p>Вторичная (бициллинопрофилактика): экстенциллин 2,4 млн единиц раз в 3 недели: </p>\r\n<ul>\r\n<li>стандартно — в течение 5 лет; </li>\r\n<li>при манифестации ОРЛ в препубертате/пубертате без порока сердца — до 18 лет; </li>\r\n<li>при манифестации ОРЛ в препубертате/пубертате с пороком сердца — до 25 лет. </li>\r\n</ul>\r\n<p>Текущая: обязательное назначение при интеркуррентных заболеваниях пенициллинов и НПВС. </p>",
"clinical_picture": "<p>Поражение сердца при ревматизме отмечается у 70-85% пациентов. При ревмокардите воспаляются все или отдельные оболочки сердца. Чаще происходит одновременное поражение эндокарда и миокарда (эндомиокардит), иногда с вовлеченностью перикарда (панкардит), возможно развитие изолированного поражения миокарда (миокардит). Во всех случаях при ревматизме в патологический процесс вовлекается миокард. </p>\r\n<p>При диффузном миокардите появляются одышка, сердцебиения, перебои и боли в сердце, кашель при физической нагрузке, в тяжелых случаях – недостаточность кровообращения, сердечная астма или отек легких. Пульс малый, тахиаритмичный. Благоприятным исходом диффузного миокардита считается миокардитический кардиосклероз. </p>\r\n<p>При эндокардите и эндомиокардите в ревматический процесс чаще вовлекается митральный (левый предсердно-желудочковый) клапан, реже аортальный и трикуспидальный (правый предсердно-желудочковый) клапаны. Клиника ревматического перикардита аналогична перикардитам иной этиологии. </p>",
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},
"code": "I10",
"name": "Эссенциальная гипертензия",
"icd_name": "Эссенциальная [первичная] гипертензия",
"gender": 0,
"age_min": 40,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 0,
"slug": "i10_essencialnaya_gipertenziya",
"lead": "заболевание, характеризующееся повышением артериального давления (более 140/90 мм рт. ст.)",
"description": "<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Эссенциальная артериальная гипертензия представляет собой повышение систолического давления крови в момент сокращения сердца и выброса крови до показателей 140 мм рт. ст. и выше этой отметки и/или диастолического давления крови в момент расслабления сердечной мышцы до отметки 90 мм рт. ст. и выше.</span></p>",
"etiology": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Наиболее вероятными причинами для беспокойства в этом плане принято считать:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">курение и злоупотребление алкоголем;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">наличие постоянных стрессов;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">некачественное вредное питание;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">проникновение в организм патогенных микроорганизмов;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">наличие большого количества соли в пище;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">период климакса у женщин.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Развиваться опасная для жизни патология может на основании расстройств деятельности ЦНС или поражения эндокринной системы. Данные факторы способствуют в первую очередь нарушениям тонуса сосудов и сильным спазмам сосудистого русла. Результатом подобных процессов в организме является чрезмерно повышенное давление. Существуют и дополнительные факторы, влияющие на развитие такого заболевания, как эссенциальная артериальная гипертензия:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">пассивный образ жизни;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">вредное воздействие экологии;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">наследственность.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"pathogenesis": "<p>Перенапряжение основных нервных механизмов регуляции артериального давления приводит к повышению возбудимости в гипоталамических центрах симпатической вегетативной нервной системы, что вызывает повышение уровня минутного выброса сердца и, следовательно, повышение артериального давления. Кроме того, происходит активация ренин-ангиотензин-альдостероновой системы, что приводит к задержке натрия в стенке сосудов, гипертрофии мышечного слоя и дисфункции эндотелия сосудов. В результате дисфункции эндотелия сосуды становятся гиперреактивными, т. е. проявляют склонность к спазму. При артериальной гипертензии также наблюдается недостаточность депрессорных механизмов (кининовой системы).</p>\r\n<p>Факторы риска развития артериальной гипертензии: возраст более 55 лет у мужчин, 65 лет – у женщин, курение, уровень холестерина выше 6,5 ммоль/л, семейный анамнез ранних сердечно-сосудистых заболеваний, ожирение, снижение липидов высокой плотности и повышение липидов низкой плотности, повышение фибриногена, снижение толерантности к глюкозе, абдоминальное ожирение, гиподинамия, социально-экономическое неблагополучие.</p>",
"diagnostics": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Виды диагностики эссенциальной гипертензии следующие:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">анализ жалоб пациента. Врач уточняет, как давно у больного появились проблемы с артериальным давлением, какие меры он предпринимал, обращался ли за лечением в больницу. Также немаловажно уточнить, какое давление у пациента является рабочим;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">анализ образа жизни: специалист обязательно проводит исследования касательно режима питания больного, его физической нагрузки, подверженности вредным факторам производства и пр.;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">проводится анализ наличия эссенциальной гипертензии у родственников больного;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">во время проведения осмотра врач выявляет шумы в сердце, хрипы в легких, признаки увеличения массы и размеров левого желудочка сердца, недостаточность сократительной функции левого желудочка, потерю эластичности и уплотнения стенок артерий;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">общий анализ крови. Позволяет выявить признаки развития воспаления в организме. Об этом факте свидетельствует повышенное содержание в крови уровня лейкоцитов;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">биохимический анализ крови. Его результаты позволяют провести оценку состояния липидного, белкового, углеводного, минерального обменов. По уровню содержания в крови микроэлементов можно провести оценку работы многих систем и органов;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">анализ мочи: определяется низкая плотность мочи, свидетельствующая о нарушениях в работе почек;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">ЭКГ (электрокардиография): выявляет увеличение размеров левого желудочка сердца, а также степень его «перегрузки»;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">ЭхоКГ (эхокардиография): дает возможность оценить размеры сердца, состояние клапанов, наличие нарушений сократительной функции сердца;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">СМАД (проведение суточного мониторинга артериального давления): обследование проводится с использованием специального прибора. Его закрепляют на поясе пациента и соединяют с манжетой, наложенной на плечо при помощи тонкого гибкого шланга. Через определенные промежутки времени прибор нагнетает воздух в манжету и измеряет артериальное давление. Все результаты исследований сохраняются в памяти прибора. Такие мероприятия позволяют с точностью определить изменения давления в течение суток и оценить эффективность лечения;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">рентгенологическое исследование органов грудной клетки: выявляют патологии в легких, расширение полости левого желудочка, изменения, вызванные уплотнением стенок сосудов и ряд других осложнений;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">ультразвуковое исследование почек: дает возможность отследить патологические процессы, вызванные заболеванием;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">исследование глазного дна при помощи офтальмоскопа. Метод позволяет выявить изменения в сосудах, служащие следствием повышенного артериального давления.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"treatment": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Выбор тактики лечения врач проводит после оценки состояния больного и стадии развития патологии. На начальных стадиях больным назначают немедикаментозную терапию, подразумевающую:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">особую диету, направленную на ограничение потребления соли и пищи с высоким содержанием животных жиров;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отказ от вредных привычек, в частности курения и злоупотребления алкогольных напитков;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">избавление от стрессов. В данном случае хорошо помогают занятия йогой, аутотренинг, сеансы у психотерапевта;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">больным с диагнозом эссенциальная гипертензия нельзя работать в условиях сильного шума и вибраций;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отказ от чрезмерных физических нагрузок: интенсивные изматывающие тренировки на беговых дорожках следует заменить получасовыми пешими прогулками.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Медикаментозное лечение подразумевает прием следующих медицинских препаратов:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">ингибиторов ангиотензинпревращающего фермента. В данную группу относят огромное количество препаратов, снижающих уровень артериального давления несколькими путями одновременно;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">блокаторы рецепторов к ангиотензину 2. Препараты расширяют сосуды, тем самым понижая артериальное давление;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">бета-блокаторы: данный вид препаратов снимает боли в сердце, замедляет сердцебиение и расширяет сосуды;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">блокаторы кальциевых каналов: замедляют проникновение кальция в ткани сосудов и сердца, замедляют сердцебиение, расширяют сосуды;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">мочегонные препараты: подавляют всасывание натрия в почках, выводя его с мочой. К этой группе препаратов причисляют и те, которые сохраняют в организме калий. При этом они обладают слабым мочегонным эффектом;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">препараты центрального действия, направленные на понижение активности нервной системы. Также сюда относятся медикаменты, понижающие содержание в организме холестерина.</span></li>\r\n</ul>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Необходимо обратить внимание на следующие пункты профилактики:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">правильное питание (избегание чрезмерного употребления мяса и животных жиров; пища должна быть умеренно калорийной, с ограниченным содержанием белков и холестерина);</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">систематический контроль веса, для людей с избыточным весом – разгрузочные диеты;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">умеренное потребления соли;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">целесообразное распределение часов работы и отдыха;</span></li>\r\n<li><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">занятия физической культурой.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>",
"clinical_picture": "<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">регулярное головокружение;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">появление головных болей;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">мелькание точек перед глазами;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">появление шума в ушах;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">покраснение лица;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">учащение сердцебиения;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">повышенная раздражительность.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">Чаще всего головная боль локализуется в области лобной или затылочной части головы. В такие периоды показатели нижнего давления могут достигать отметки до 95 мм рт. ст., верхнего — до 150. Второстепенные симптомы могут быть и такими:</span></p>\r\n<ul>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">пульсация в голове;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">беспокойство;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">тошнота;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">рвота;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">одышка;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">потливость;</span></li>\r\n<li><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">отечность.</span></li>\r\n</ul>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"> </p>\r\n<p><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\"> </span></p>",
"image": "http://api.symptomd.ru/storage/e9b8e723fc1254364b6954999a195910_XyLhQ9F.jpg",
"image_alt": "гипертоническая болезнь",
"standard_type": 1,
"danger": 51,
"published": 1,
"parent": null,
"block_rubric": 92,
"standards": [
5173,
5396
]
},
{
"id": 10986,
"symptoms": [],
"alternative_names": [],
"complications": [],
"medicine_branches": [],
"who": [
{
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},
{
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