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"lead": "наследственное заболевание кожи, характеризующееся диффузным нарушением кератинизации по типу гиперкератоза.",
"description": "<p>Ихтиоз - это <span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">болезнь кожных покровов, при которой у человека нарушается процесс ороговения эпидермиса, в результате чего на нем появляются твердые чешуйки.</span></p>",
"etiology": "<p>Основная причина ихтиоза – это генная мутация. Эта мутация передается из поколения в поколение. Причем в некоторых случаях она связана с Х-хромосомой (женской). В этом случае женщины – всего лишь носительницы измененного гена, а вот мужчины с такой хромосомой страдают ихтиозом.</p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нарушения белкового обмена, когда в крови накапливаются аминокислоты и нарушения жирового обмена, которые проявляются повышенным содержанием холестерина, являются основным проявлением генной мутации, которая приводит к ихтиозу.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Все процессы обмена веществ снижаются, терморегуляция организма нарушается, а активность ферментов в окислительных процессах кожного дыхания наоборот усиливается. У пациентов с генной мутацией, которая является причиной ихтиоза, постепенно нарастают или же появляются сразу снижение активности щитовидной железы, надпочечников и половых желез, увеличивается дефицит гуморального и клеточного иммунитета. Нарушение усвоения витамина А вместе со сниженными функциями потовых желез и приводят к нарушению ороговения кожи в сторону гиперкератоза, так как происходит избыточная продукция кератина с измененной структурой, что вместе с замедлением процесса отторжения ороговевшего слоя эпидермиса и вызывает проявления ихтиоза. При ихтиозе между чешуйками скапливаются аминокислотные комплексы, которые обладают цементирующим действием, поэтому чешуйки плотно сцеплены между собой, а их отделение от тела резко болезненно.</span></p>",
"diagnostics": "<p>При подозрении на ихтиоз нужно обратиться к дерматовенерологу, сдать общий и биохимический анализы крови, общий анализ мочи и соскоб кожи на гистологическое исследование. Диагноз ставится на основании характерных симптомов и результатов анализов.</p>\r\n<p>Пренатальную диагностику проводят в том случае, если кто-то из членов семьи родителей страдает ихтиозом. В этом случае в период между 19-й и 21-й неделей делают биопсию кожи плода. Таким образом, можно диагностировать «плод Арлекина».</p>",
"treatment": "<p>Ихтиоз неизлечим. Однако можно снизить тяжесть проявлений и уменьшить частоту обострений. Для этого назначают витамин А курсами по 2-3 месяца, витамины Е, РР, С и группы В. В некоторых случаях назначают кортикостероидные гормоны.</p>\r\n<p>Страдающему ихтиозом обязательно нужно тщательно ухаживать за кожей. Нужно очень сильно увлажнять ее, так как она склонна к сухости. Причем увлажняющий крем обязательно должен содержать витамин А. Взрослым врачи рекомендуют использовать салициловую мазь и мазь с мочевиной для размягчения ороговевших участков кожи.</p>\r\n<p>Страдающим ихтиозом показана бальнеотерапия – ванны с крахмалом, мочевиной, винилином, углекислые ванны. Они стимулируют обмен веществ в тканях и улучшают состояние кожи. Полезно и обертывание грязями.</p>",
"prevention": "<p>Ихтиоз – заболевание, передающееся по наследству. Единственный способ профилактики – это медико-генетическое консультирование и пренатальная диагностика в случае, если есть риск рождения ребенка, страдающего ихтиозом.</p>",
"clinical_picture": "<p>Самая распространенная форма – это простой или вульгарный ихтиоз. В большинстве случаев он проявляется уже на первом году жизни ребенка, но может начаться и через три года после рождения. У таких детей кожа сухая, шелушащаяся, особенно на ногах. При этом кожа на лице и в зоне, где тело ребенка соприкасается с подгузниками, нормальная. На ладонях и подошвах у этих детей кожа складчатая.</p>\r\n<p>По мере взросления состояние кожи у многих становится лучше, однако складчатость на ладонях и стопах остается на всю жизнь.</p>",
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"description": "<p>Ихтиоз - это <span style=\"background-color: transparent; font-family: Verdana; font-size: 7pt; white-space: pre-wrap;\">болезнь кожных покровов, при которой у человека нарушается процесс ороговения эпидермиса, в результате чего на нем появляются твердые чешуйки.</span></p>",
"etiology": "<p>Основная причина ихтиоза – это генная мутация. Эта мутация передается из поколения в поколение. Причем в некоторых случаях она связана с Х-хромосомой (женской). В этом случае женщины – всего лишь носительницы измененного гена, а вот мужчины с такой хромосомой страдают ихтиозом.</p>",
"pathogenesis": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Нарушения белкового обмена, когда в крови накапливаются аминокислоты и нарушения жирового обмена, которые проявляются повышенным содержанием холестерина, являются основным проявлением генной мутации, которая приводит к ихтиозу.</span></p>\r\n<p> </p>\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 6.999999999999999pt; font-family: Verdana; color: #000000; background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;\">Все процессы обмена веществ снижаются, терморегуляция организма нарушается, а активность ферментов в окислительных процессах кожного дыхания наоборот усиливается. У пациентов с генной мутацией, которая является причиной ихтиоза, постепенно нарастают или же появляются сразу снижение активности щитовидной железы, надпочечников и половых желез, увеличивается дефицит гуморального и клеточного иммунитета. Нарушение усвоения витамина А вместе со сниженными функциями потовых желез и приводят к нарушению ороговения кожи в сторону гиперкератоза, так как происходит избыточная продукция кератина с измененной структурой, что вместе с замедлением процесса отторжения ороговевшего слоя эпидермиса и вызывает проявления ихтиоза. При ихтиозе между чешуйками скапливаются аминокислотные комплексы, которые обладают цементирующим действием, поэтому чешуйки плотно сцеплены между собой, а их отделение от тела резко болезненно.</span></p>",
"diagnostics": "<p>При подозрении на ихтиоз нужно обратиться к дерматовенерологу, сдать общий и биохимический анализы крови, общий анализ мочи и соскоб кожи на гистологическое исследование. Диагноз ставится на основании характерных симптомов и результатов анализов.</p>\r\n<p>Пренатальную диагностику проводят в том случае, если кто-то из членов семьи родителей страдает ихтиозом. В этом случае в период между 19-й и 21-й неделей делают биопсию кожи плода. Таким образом, можно диагностировать «плод Арлекина».</p>",
"treatment": "<p>Ихтиоз неизлечим. Однако можно снизить тяжесть проявлений и уменьшить частоту обострений. Для этого назначают витамин А курсами по 2-3 месяца, витамины Е, РР, С и группы В. В некоторых случаях назначают кортикостероидные гормоны.</p>\r\n<p>Страдающему ихтиозом обязательно нужно тщательно ухаживать за кожей. Нужно очень сильно увлажнять ее, так как она склонна к сухости. Причем увлажняющий крем обязательно должен содержать витамин А. Взрослым врачи рекомендуют использовать салициловую мазь и мазь с мочевиной для размягчения ороговевших участков кожи.</p>\r\n<p>Страдающим ихтиозом показана бальнеотерапия – ванны с крахмалом, мочевиной, винилином, углекислые ванны. Они стимулируют обмен веществ в тканях и улучшают состояние кожи. Полезно и обертывание грязями.</p>",
"prevention": "<p>Ихтиоз – заболевание, передающееся по наследству. Единственный способ профилактики – это медико-генетическое консультирование и пренатальная диагностика в случае, если есть риск рождения ребенка, страдающего ихтиозом.</p>",
"clinical_picture": "<p>Самая распространенная форма – это простой или вульгарный ихтиоз. В большинстве случаев он проявляется уже на первом году жизни ребенка, но может начаться и через три года после рождения. У таких детей кожа сухая, шелушащаяся, особенно на ногах. При этом кожа на лице и в зоне, где тело ребенка соприкасается с подгузниками, нормальная. На ладонях и подошвах у этих детей кожа складчатая.</p>\r\n<p>По мере взросления состояние кожи у многих становится лучше, однако складчатость на ладонях и стопах остается на всю жизнь.</p>",
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},
"code": "L20",
"name": "Атопический дерматит",
"icd_name": "Атопический дерматит",
"gender": 0,
"age_min": 0,
"age_max": 100,
"cause": [
"0"
],
"periodicity": 3,
"slug": "l20_atopicheskiy_dermatit",
"lead": "мультифакториальное воспалительное заболевание кожи, характеризующееся зудом, хроническим рецидивирующим течением и возрастными особенностями локализации и морфологии очагов поражения.",
"description": "<p>Атопический дерматит — одно из наиболее распространенных заболеваний (от 20% до 40% в структуре кожных заболеваний), встречающееся во всех странах, у лиц обоих полов и в разных возрастных группах.</p>",
"etiology": "<p>Причины атопического дерматита разнообразны. Главная из них – наследственность генетических факторов, способствующих формированию патологии. В случае заболевания атопическим дерматитом обоих родителей, риск развития патологии у ребенка составляет 81 %. Если болен только один родитель, риск составляет 56 %, причем он повышается, если больна мать. У однояйцевых близнецов частота атопического дерматита составляет 80 %, у разнояйцовых – 20 %.</p>\r\n<p>Преимущественно развитие болезни провоцируется аллергическими реакциями, чаще всего на пищу, немедленного или замедленного типа. Среди остальных причин – стрессы, умственные нагрузки, психологические расстройства, заболевания различных систем организма, в том числе эндокринной и пищеварительной систем.</p>",
"pathogenesis": "<p>В патогенезе АтД важную роль играет наследственная детерминированность, приводящая к нарушению состояния кожного барьера, дефектам иммунной системы (стимуляция Th2-клеток с последующей гиперпродукцией IgE), гиперчувствительности к аллергенам и неспецифическим раздражителям, колонизации патогенными микроорганизмами (Staphylococcus aureus, Malassezia furfur), а также дисбалансу вегетативной нервной системы с повышением продукции медиаторов воспаления.</p>",
"diagnostics": "<p>Обязательные лабораторные исследования:</p>\r\n<p>1. Клинический анализ крови.</p>\r\n<p>2. Клинический анализ мочи.</p>\r\n<p>3. Биохимический анализ крови.</p>\r\n<p> </p>\r\n<p>Дополнительные лабораторные исследования:</p>\r\n<p>1. Определение уровня общего IgE в сыворотке крови методом иммуноферментного анализа.</p>\r\n<p>2. Аллергологическое исследование сыворотки крови — определение специфических IgE к пищевым, бытовым антигенам, антигенам растительного, животного и химического происхождения.</p>\r\n<p> </p>",
"treatment": "<p>Лечение атопического дерматита должно преследовать несколько целей:</p>\r\n<ul>\r\n<li>элиминационная терапия – прекращение контакта больного с аллергеном и прием противоаллергических препаратов;</li>\r\n<li>базисная терапия – подавление воспалительного процесса в коже;</li>\r\n<li>лечение сопутствующих заболеваний;</li>\r\n<li>коррекция иммунных нарушений, укрепление иммунитета.</li>\r\n</ul>\r\n<p>Лечение атопического дерматита проходит только под контролем врача, который подбирает необходимые препараты и регулирует длительность их применения.</p>\r\n<p>Противоаллергические средства внутреннего приема назначаются для блокады воздействия гистамина на организм, вследствие этого происходит торможение воспалительных процессов в коже. Прием антигистаминных препаратов может быть длительным (от 2 недель до 4 месяцев), возможна комбинация средств различных поколений. Стоит отметить, что существует 3 поколения лекарственных препаратов после аллергии, и с каждым последующим поколением уменьшается вероятность привыкания, количество и сила побочных эффектов и увеличивается продолжительность действия.</p>\r\n<p>Препараты после аллергии принимают 1 раз в день. При длительном приеме возможно чередование нескольких препаратов по 1-2 месяцам. Так как даже препараты последнего поколения нередко вызывают <a title=\"Перейти на страницу симптома Сонливость\" href=\"/symptom/sonlivost/\">сонливость</a>, их предпочтительно принимать перед сном.</p>\r\n<p>Антигистаминной активностью обладают препараты, в составе которых присутствуют следующие вещества:</p>\r\n<ul>\r\n<li>первое поколение: клемастин, прометазин, хлорфенамин, диметинден, мебгидролин, дифенгидрамин, хлоропирамин, меклизин;</li>\r\n<li>второе поколение: азеластин, астемизол, акривастин, эбасин, цетризин, терфенадин, лоратадин;</li>\r\n<li>третье поколение: сехифенадин, хифенадин, фексофенадин, дезлоратадин, левоцетризин.</li>\r\n</ul>\r\n<p>Для лечения атопического дерматита обычно используются антигистаминные препараты в форме таблеток или растворов для инъекций.</p>\r\n<p>Лечение атопического дерматита преследует несколько целей: избавление пациента от симптомов, главным из которых является <a title=\"Перейти на страницу симптома Зуд\" href=\"/symptom/zud/\">зуд</a>, и профилактика обострений. Основная часть терапии представляет собой использование наружных средств, таких как:</p>\r\n<ul>\r\n<li>мази – препараты, изготавливаемые на основе жиров или жироподобных веществ и лечебного вещества, обладающие смягчающими, согревающими и питательными эффектами;</li>\r\n<li>кремы – препараты на водной основе, с меньшим содержанием лечебных веществ, лучшей впитываемостью и охлаждающим эффектом;</li>\r\n<li>гели – смеси из высокомолекулярных и низкомолекулярных веществ;</li>\r\n<li>пасты – смеси равных частей мази и порошка, обладают антиэкссудативным эффектом;</li>\r\n<li>примочки – водный раствор противовоспалительных, противозудных, дезинфицирующих веществ, часто средств фитотерапии. Благодаря способу применения примочка впитывает <a title=\"Перейти на страницу симптома Выпот\" href=\"/symptom/vypot/\">экссудат</a> из эрозивных участков и обладает подсушивающим эффектом;</li>\r\n<li>болтушки (взбалтываемые взсеси) – смесь растительных масел либо воды и водно-спиртового раствора с добавлением порошка. Оказывают антиэкссудативное и противозудное действия;</li>\r\n<li>пластыри – используются преимущественно в хроническом периоде в местах утолщения кожи. Представляют собой смесь воска, полимеров, смол, окиси цинка, натуральных масел.</li>\r\n</ul>\r\n<p>Противовоспалительной и противозудной активностью обладают глюкокортикостероидные препараты, нестероидные противовоспалительные средства (например, с пимекролимусом, раствором тиосульфата натрия), жидкость Бурова, свинцовая примочка, нитрат серебра, отвары и настои череды лекарственных трав. К наружной фитотерапии рекомендуется прибегать в хронический период атопического дерматита. Такие растения и их части, как вероника лекарственная, березовые почки, огуречник, кора дуба, листья груши, базилик, цветы ромашки и иван-чая, могут снять <a title=\"Перейти на страницу симптома Зуд\" href=\"/symptom/zud/\">зуд</a> и <a title=\"Перейти на страницу симптома Покраснение кожи\" href=\"/symptom/pokrasnenie_kozhi/\">покраснение</a>, уменьшить <a title=\"Перейти на страницу симптома воспаление\" href=\"/symptom/vospalenie/\">воспаление</a> и ускорить заживление кожи. Растительные компоненты входят в большинство наружных препаратов, предназначенных для лечения атопического дерматита, а также их можно использовать для лечебных ванн и примочек.</p>\r\n<p>При инфильтрации и утолщении кожи применяют рассасывающие (редуцирующие) мази, пластыри и кремы с нафталанской нефтью, серой, дегтем, ихтиолом, метилурациловой мазью. В начале лечения назначаются более слабые вещества в малой дозе. Постепенно концентрацию действующих веществ увеличивают, а слабые компоненты заменяют более мощными.</p>\r\n<p> </p>",
"prevention": "<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">К профилактике заболевания относят:</span></p>\r\n<ul style=\"margin-top: 0; margin-bottom: 0; padding-inline-start: 48px;\">\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">обучение пациента и членов его семьи правилам ухода за кожей, грамотному использованию лекарств и пр.;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">консультирование по поводу коррекции факторов риска развития неинфекционных заболеваний;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">проведение мероприятий по сохранению беременности у пациенток с атопическим дерматитом, начиная с первой половины срока беременности;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">соблюдение диеты кормящей матерью и новорождённым;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">лечение сопутствующих заболеваний;</span></p>\r\n</li>\r\n<li style=\"list-style-type: disc; font-size: 7pt; font-family: Verdana; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre;\" dir=\"ltr\">\r\n<p style=\"line-height: 1.38; margin-top: 0pt; margin-bottom: 0pt;\" dir=\"ltr\"><span style=\"font-size: 7pt; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; vertical-align: baseline; white-space: pre-wrap;\">длительный приём \"Дезлоратадина\".</span></p>\r\n</li>\r\n</ul>",
"clinical_picture": "<p>Экссудативная форма наблюдается преимущественно у детей грудного возраста, характеризуется симметричными эритематозными, папуловезикулезными высыпаниями на коже лица и волосистой части головы, отмеча- ется экссудация с образованием чешуйкокорок. В дальнейшем <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">высыпания</a> распространяются на кожу наружной поверхности голеней, предплечий, туловища и ягодиц, а также могут появляться в естественных складках кожи. Дермографизм красный или смешанный. Субъективно отмечается <a title=\"Перейти на страницу симптома Зуд\" href=\"/symptom/zud/\">зуд</a> кожных покровов различной интенсивности. Эритематозно-сквамозная форма чаще наблюдается у детей в возрасте от 1,5 до 3 лет, характеризуется наличием зудящих узелков, эрозий и экскориаций, а также незначительной эритемой и инфильтрацией в области высыпаний на коже туловища, верхних и нижних конечностей, реже — на коже лица. Дермографизм розовый или смешанный. Эритематозно-сквамозная форма с лихенификацией наблюдается у детей в возрасте от 3 лет и взрослых лиц, характеризуется эритематозно-сквамозными и папулезными очагами. Кожа сухая, лихенифицированная, с большим количеством экскориаций и мелкопластинчатых чешуек. <a title=\"Перейти на страницу симптома Сыпь\" href=\"/symptom/syp/\">Высыпания</a> локализуются преимущественно на сгибательной поверхности конечностей, тыльной поверхности кистей, передней и боковой поверхностях шеи. 43 Атопический дерматит Наблюдаются гиперпигментация кожи периорбитальной области, появ- ление складки под нижним веком (линии Денни — Моргана). Отмечается повышенная <a title=\"Перейти на страницу симптома Изменения структуры кожи\" href=\"/symptom/izmeneniya_struktury_kozhi/\">сухость кожи</a>. Дермографизм белый стойкий или смешанный. <a title=\"Перейти на страницу симптома Зуд\" href=\"/symptom/zud/\">Зуд</a> выраженный, постоянный, реже — приступообразный. Лихеноидная форма наблюдается чаще всего у подростков и характеризуется сухостью, выраженным рисунком, отечностью и инфильтрацией кожных покровов. Имеются крупные сливающиеся очаги лихенизации кожи. <a title=\"Перейти на страницу симптома Зуд\" href=\"/symptom/zud/\">Зуд</a> упорный, стойкий. Пруригинозная форма наблюдается относительно редко, чаще у взрослых лиц и характеризуется высыпаниями в виде множественных изолированных плотных отечных папул, на вершинах которых могут появляться мелкие пузырьки. Очаги поражения могут иметь распространенный характер с преимущественной локализацией на коже конечностей. Дермографизм выраженный белый стойкий. Наиболее тяжелым проявлением АтД является эритродермия, которая характеризуется универсальным поражением кожных покровов в виде эрите- мы, инфильтрации, лихенификации, шелушения и сопровождается симптомами интоксикации и нарушением терморегуляции (<a title=\"Перейти на страницу симптома Высокая температура 38-42° \" href=\"/symptom/vysokaya_temperatura_38-42/\">гипертермия</a>, <a title=\"Перейти на страницу симптома Озноб\" href=\"/symptom/oznob/\">озноб</a>, <a title=\"Перейти на страницу симптома Увеличение лимфатических узлов\" href=\"/symptom/uvelichenie_limfaticheskih_uzlov/\">лимфаденопатия</a>). </p>",
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